Details for: REV3L
Gene ID: 5980
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: REV3L
Ensembl ID: ENSG00000009413
Description: REV3 like, DNA directed polymerase zeta catalytic subunit
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 74.68rCSI 89.2%PRS 11.3
-
CSI 65.5rCSI 84.44%PRS 12.06
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CSI 64.93rCSI 80.78%PRS 10.73
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CSI 53.89rCSI 86.67%PRS 12.54
-
CSI 50.6rCSI 84.94%PRS 11.51
-
CSI 49.09rCSI 86.69%PRS 11.45
-
CSI 48.57rCSI 88.26%PRS 16.35
-
CSI 45.75rCSI 92.82%PRS 9.76
-
CSI 44.64rCSI 83.61%PRS 13.99
-
CSI 40.06rCSI 88.16%PRS 15.58
-
CSI 36.23rCSI 46.52%PRS 18.94
-
CSI 33.02rCSI 74.03%PRS 12.03
-
CSI 31.3rCSI 76.07%PRS 11.3
-
CSI 31.23rCSI 45.91%PRS 17.93
-
CSI 30.82rCSI 74.09%PRS 28.7
-
CSI 30.71rCSI 44.07%PRS 15.11
-
CSI 27.13rCSI 48.75%PRS 16.14
-
CSI 26.6rCSI 70.85%PRS 16.45
-
CSI 26.15rCSI 81.79%PRS 13.21
-
CSI 25.17rCSI 17.5%PRS 23.29
-
CSI 24.71rCSI 54.59%PRS 13.97
-
CSI 24.7rCSI 64.34%PRS 19.44
-
CSI 24.35rCSI 76.11%PRS 12.27
-
CSI 23.08rCSI 79.05%PRS 16.87
-
CSI 21.81rCSI 20.29%PRS 19.55
-
CSI 21.38rCSI 76.95%PRS 10.82
-
CSI 21.13rCSI 18.13%PRS 31.9
-
CSI 21.03rCSI 79.49%PRS 11.85
-
CSI 20.19rCSI 94.96%PRS 21.03
-
CSI 19.66rCSI 32.2%PRS 15
-
CSI 18.86rCSI 26.19%PRS 19.93
-
CSI 18.05rCSI 67.63%PRS 16.44
-
CSI 17.44rCSI 25.57%PRS 25.59
-
CSI 17.29rCSI 27.57%PRS 16.7
-
CSI 16.8rCSI 15.43%PRS 22.75
-
CSI 15.49rCSI 12.51%PRS 30.43
-
CSI 15.13rCSI 61.04%PRS 17.62
-
CSI 14.54rCSI 29.18%PRS 14.43
-
CSI 14.52rCSI 12.02%PRS 19.75
-
CSI 14.51rCSI 25.97%PRS 18.04
-
CSI 14.45rCSI 80.56%PRS 48.55
-
CSI 14.36rCSI 46.72%PRS 23.62
-
CSI 14.36rCSI 9.54%PRS 23.35
-
CSI 13.82rCSI 10.45%PRS 26.67
-
CSI 13.82rCSI 30.43%PRS 29.55
-
CSI 13.7rCSI 97.95%PRS 20.33
-
CSI 13.58rCSI 19.68%PRS 29.26
-
CSI 13.37rCSI 23.12%PRS 14.86
-
CSI 13.15rCSI 69.14%PRS 22.94
-
CSI 13.12rCSI 77.27%PRS 12.03
-
CSI 12.85rCSI 14.83%PRS 17.07
-
CSI 12.63rCSI 36.59%PRS 14.96
-
CSI 12.36rCSI 10.85%PRS 22.4
-
CSI 12.21rCSI 41.37%PRS 20.2
-
CSI 12.04rCSI 9.16%PRS 25.73
-
CSI 12.02rCSI 9.5%PRS 13.37
-
CSI 11.78rCSI 58.58%PRS 21.05
-
CSI 11.77rCSI 27.18%PRS 15.72
-
CSI 11.71rCSI 16.01%PRS 22.06
-
CSI 11.5rCSI 86.47%PRS 19.79
-
CSI 11.47rCSI 76.13%PRS 20.8
-
CSI 11.46rCSI 50.36%PRS 17.18
-
CSI 11.43rCSI 84.05%PRS 11.33
-
CSI 11.37rCSI 29.54%PRS 25.11
-
CSI 11.08rCSI 15.34%PRS 27.54
-
CSI 10.89rCSI 12.76%PRS 26.67
-
CSI 10.85rCSI 17.25%PRS 16.45
-
CSI 10.78rCSI 15.55%PRS 27.22
-
CSI 10.75rCSI 51.49%PRS 15.11
-
CSI 10.68rCSI 29.43%PRS 18.11
-
CSI 10.65rCSI 34.55%PRS 23.49
-
CSI 10.42rCSI 9.13%PRS 25.97
-
CSI 10.32rCSI 7.41%PRS 26.74
-
CSI 10.29rCSI 19.61%PRS 30.79
-
CSI 10.21rCSI 7.11%PRS 27.5
-
CSI 10.19rCSI 17.87%PRS 14.72
-
CSI 10.16rCSI 26.28%PRS 18.15
-
CSI 10.13rCSI 49.95%PRS 26.41
-
CSI 10.03rCSI 9.66%PRS 20.18
-
CSI 9.97rCSI 14.22%PRS 21.94
-
CSI 9.96rCSI 10.25%PRS 31.54
-
CSI 9.88rCSI 58.32%PRS 20.98
-
CSI 9.83rCSI 76.18%PRS 21
-
CSI 9.81rCSI 37.02%PRS 26.16
-
CSI 9.73rCSI 7.27%PRS 32.7
-
CSI 9.67rCSI 8.5%PRS 14.17
-
CSI 9.63rCSI 21.21%PRS 22
-
CSI 9.63rCSI 22.02%PRS 18.93
-
CSI 9.56rCSI 15.39%PRS 14.92
-
CSI 9.35rCSI 7.49%PRS 34.7
-
CSI 9.35rCSI 23.72%PRS 14.79
-
CSI 9.31rCSI 7.17%PRS 18.03
-
CSI 9.06rCSI 8.25%PRS 29.68
-
CSI 9.05rCSI 12.37%PRS 21.59
-
CSI 8.97rCSI 18.62%PRS 19.44
-
CSI 8.95rCSI 13.76%PRS 26.76
-
CSI 8.86rCSI 21.94%PRS 18.01
-
CSI 8.85rCSI 26.12%PRS 23.46
-
CSI 8.84rCSI 13.14%PRS 23.26
-
CSI 8.81rCSI 12.46%PRS 26.82
-
CSI -3.0rCSI -4.1%PRS 17.2%
-
CSI 0.1rCSI 1.8%PRS 46.3%
-
CSI 0.2rCSI 2.7%PRS 34.6%
-
CSI 0.3rCSI 2.2%PRS 37.6%
-
CSI 0.3rCSI 1.3%PRS 32.0%
-
CSI 0.5rCSI 2.7%PRS 28.9%
-
CSI 0.6rCSI 4.5%PRS 50.6%
-
CSI 0.6rCSI 3.1%PRS 25.7%
-
CSI 0.6rCSI 1.5%PRS 34.6%
-
CSI 0.7rCSI 2.3%PRS 31.1%
-
CSI 0.8rCSI 3.5%PRS 46.7%
-
CSI 0.9rCSI 8.0%PRS 62.4%
-
CSI 0.9rCSI 3.8%PRS 33.3%
-
CSI 1.0rCSI 3.6%PRS 33.4%
-
CSI 1.0rCSI 10.5%PRS 25.4%
-
CSI 1.0rCSI 7.3%PRS 22.0%
-
CSI 1.1rCSI 4.1%PRS 38.3%
-
CSI 1.1rCSI 6.9%PRS 72.2%
-
CSI 1.2rCSI 8.8%PRS 35.4%
-
CSI 1.2rCSI 1.6%PRS 21.4%
-
CSI 1.2rCSI 6.3%PRS 33.3%
-
CSI 1.3rCSI 2.5%PRS 19.9%
-
CSI 1.3rCSI 4.2%PRS 50.4%
-
CSI 1.3rCSI 16.6%PRS 57.5%
-
CSI 1.3rCSI 1.9%PRS 30.4%
-
CSI 1.3rCSI 7.7%PRS 29.3%
-
CSI 1.4rCSI 8.5%PRS 47.8%
-
CSI 1.4rCSI 4.0%PRS 36.3%
-
CSI 1.4rCSI 2.1%PRS 22.3%
-
CSI 1.4rCSI 1.7%PRS 33.6%
-
CSI 1.4rCSI 6.6%PRS 43.0%
-
CSI 1.4rCSI 7.6%PRS 34.4%
-
CSI 1.4rCSI 6.7%PRS 48.0%
-
CSI 1.4rCSI 4.1%PRS 34.2%
-
CSI 1.4rCSI 8.3%PRS 28.6%
-
CSI 1.6rCSI 6.1%PRS 41.0%
-
CSI 1.6rCSI 4.0%PRS 52.1%
-
CSI 1.7rCSI 5.4%PRS 27.9%
-
CSI 1.7rCSI 11.0%PRS 42.5%
-
CSI 1.7rCSI 9.5%PRS 50.3%
-
CSI 1.7rCSI 14.9%PRS 30.4%
-
CSI 1.8rCSI 2.7%PRS 34.0%
-
CSI 1.8rCSI 2.4%PRS 36.9%
-
CSI 1.8rCSI 4.8%PRS 31.0%
-
CSI 1.8rCSI 8.1%PRS 35.8%
-
CSI 1.9rCSI 6.6%PRS 31.6%
-
CSI 1.9rCSI 2.7%PRS 20.7%
-
CSI 1.9rCSI 4.4%PRS 29.1%
-
CSI 1.9rCSI 1.6%PRS 24.4%
-
CSI 1.9rCSI 5.2%PRS 31.9%
-
CSI 1.9rCSI 3.0%PRS 23.3%
-
CSI 2.0rCSI 2.4%PRS 17.1%
-
CSI 2.1rCSI 3.9%PRS 41.0%
-
CSI 2.1rCSI 5.4%PRS 48.8%
-
CSI 2.1rCSI 2.2%PRS 20.3%
-
CSI 2.2rCSI 9.9%PRS 40.1%
-
CSI 2.2rCSI 10.1%PRS 59.9%
-
CSI 2.3rCSI 1.9%PRS 21.9%
-
CSI 2.3rCSI 9.3%PRS 27.4%
-
CSI 2.3rCSI 2.9%PRS 22.6%
-
CSI 2.3rCSI 4.5%PRS 46.6%
-
CSI 2.3rCSI 4.6%PRS 32.4%
-
CSI 2.3rCSI 5.4%PRS 38.5%
-
CSI 2.3rCSI 5.2%PRS 38.2%
-
CSI 2.4rCSI 4.2%PRS 25.6%
-
CSI 2.5rCSI 12.8%PRS 37.7%
-
CSI 2.5rCSI 9.7%PRS 6.5%
-
CSI 2.5rCSI 22.0%PRS 12.9%
-
CSI 2.5rCSI 6.6%PRS 37.6%
-
CSI 2.6rCSI 6.9%PRS 25.2%
-
CSI 2.6rCSI 4.1%PRS 19.6%
-
CSI 2.6rCSI 16.5%PRS 13.2%
-
CSI 2.8rCSI 3.3%PRS 23.3%
-
CSI 2.8rCSI 26.0%PRS 49.9%
-
CSI 2.9rCSI 29.5%PRS 22.5%
-
CSI 2.9rCSI 3.7%PRS 22.6%
-
CSI 2.9rCSI 3.3%PRS 31.1%
-
CSI 3.0rCSI 2.4%PRS 34.5%
-
CSI 3.0rCSI 15.7%PRS 33.0%
-
CSI 3.1rCSI 3.1%PRS 21.1%
-
CSI 3.1rCSI 4.8%PRS 19.6%
-
CSI 3.2rCSI 7.5%PRS 22.4%
-
CSI 3.2rCSI 14.1%PRS 19.1%
-
CSI 3.2rCSI 8.2%PRS 48.3%
-
CSI 3.2rCSI 8.9%PRS 30.1%
-
CSI 3.2rCSI 35.9%PRS 45.6%
-
CSI 3.3rCSI 14.5%PRS 11.8%
-
CSI 3.3rCSI 8.5%PRS 29.7%
-
CSI 3.3rCSI 79.9%PRS 10.8%
-
CSI 3.3rCSI 4.2%PRS 25.2%
-
CSI 3.4rCSI 80.2%PRS 9.8%
-
CSI 3.5rCSI 4.5%PRS 27.8%
-
CSI 3.5rCSI 21.7%PRS 15.2%
-
CSI 3.5rCSI 7.2%PRS 29.0%
-
CSI 3.5rCSI 3.1%PRS 19.6%
-
CSI 3.6rCSI 10.3%PRS 22.0%
-
CSI 3.7rCSI 3.8%PRS 23.0%
-
CSI 3.7rCSI 5.7%PRS 29.0%
-
CSI 3.7rCSI 10.3%PRS 26.2%
-
CSI 3.7rCSI 7.7%PRS 19.4%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 2657122083
Symbol: REV3L_HUMAN
Name: DNA polymerase zeta catalytic subunit
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9618506
Title: A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta.
PubMed ID: 9618506
PubMed ID: 10102035
Title: A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans.
PubMed ID: 10102035
PubMed ID: 9925914
Title: Alternative splicing, genomic structure, and fine chromosome localization of REV3L.
PubMed ID: 9925914
DOI: 10.1159/000015157
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 10660610
Title: A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2.
PubMed ID: 10660610
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24449906
Title: Human Pol zeta purified with accessory subunits is active in translesion DNA synthesis and complements Pol eta in cisplatin bypass.
PubMed ID: 24449906
PubMed ID: 20164194
Title: Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1.
PubMed ID: 20164194
Sequence Information:
- Length: 3130
- Mass: 352776
- Checksum: 4FBAA214639DF3C6
- Sequence:
MFSVRIVTAD YYMASPLQGL DTCQSPLTQA PVKKVPVVRV FGATPAGQKT CLHLHGIFPY LYVPYDGYGQ QPESYLSQMA FSIDRALNVA LGNPSSTAQH VFKVSLVSGM PFYGYHEKER HFMKIYLYNP TMVKRICELL QSGAIMNKFY QPHEAHIPYL LQLFIDYNLY GMNLINLAAV KFRKARRKSN TLHATGSCKN HLSGNSLADT LFRWEQDEIP SSLILEGVEP QSTCELEVDA VAADILNRLD IEAQIGGNPG LQAIWEDEKQ RRRNRNETSQ MSQPESQDHR FVPATESEKK FQKRLQEILK QNDFSVTLSG SVDYSDGSQE FSAELTLHSE VLSPEMLQCT PANMVEVHKD KESSKGHTRH KVEEALINEE AILNLMENSQ TFQPLTQRLS ESPVFMDSSP DEALVHLLAG LESDGYRGER NRMPSPCRSF GNNKYPQNSD DEENEPQIEK EEMELSLVMS QRWDSNIEEH CAKKRSLCRN THRSSTEDDD SSSGEEMEWS DNSLLLASLS IPQLDGTADE NSDNPLNNEN SRTHSSVIAT SKLSVKPSIF HKDAATLEPS SSAKITFQCK HTSALSSHVL NKEDLIEDLS QTNKNTEKGL DNSVTSFTNE STYSMKYPGS LSSTVHSENS HKENSKKEIL PVSSCESSIF DYEEDIPSVT RQVPSRKYTN IRKIEKDSPF IHMHRHPNEN TLGKNSFNFS DLNHSKNKVS SEGNEKGNST ALSSLFPSSF TENCELLSCS GENRTMVHSL NSTADESGLN KLKIRYEEFQ EHKTEKPSLS QQAAHYMFFP SVVLSNCLTR PQKLSPVTYK LQPGNKPSRL KLNKRKLAGH QETSTKSSET GSTKDNFIQN NPCNSNPEKD NALASDLTKT TRGAFENKTP TDGFIDCHFG DGTLETEQSF GLYGNKYTLR AKRKVNYETE DSESSFVTHN SKISLPHPME IGESLDGTLK SRKRRKMSKK LPPVIIKYII INRFRGRKNM LVKLGKIDSK EKQVILTEEK MELYKKLAPL KDFWPKVPDS PATKYPIYPL TPKKSHRRKS KHKSAKKKTG KQQRTNNENI KRTLSFRKKR SHAILSPPSP SYNAETEDCD LNYSDVMSKL GFLSERSTSP INSSPPRCWS PTDPRAEEIM AAAEKEAMLF KGPNVYKKTV NSRIGKTSRA RAQIKKSKAK LANPSIVTKK RNKRNQTNKL VDDGKKKPRA KQKTNEKGTS RKHTTLKDEK IKSQSGAEVK FVLKHQNVSE FASSSGGSQL LFKQKDMPLM GSAVDHPLSA SLPTGINAQQ KLSGCFSSFL ESKKSVDLQT FPSSRDDLHP SVVCNSIGPG VSKINVQRPH NQSAMFTLKE STLIQKNIFD LSNHLSQVAQ NTQISSGMSS KIEDNANNIQ RNYLSSIGKL SEYRNSLESK LDQAYTPNFL HCKDSQQQIV CIAEQSKHSE TCSPGNTASE ESQMPNNCFV TSLRSPIKQI AWEQKQRGFI LDMSNFKPER VKPRSLSEAI SQTKALSQCK NRNVSTPSAF GEGQSGLAVL KELLQKRQQK AQNANTTQDP LSNKHQPNKN ISGSLEHNKA NKRTRSVTSP RKPRTPRSTK QKEKIPKLLK VDSLNLQNSS QLDNSVSDDS PIFFSDPGFE SCYSLEDSLS PEHNYNFDIN TIGQTGFCSF YSGSQFVPAD QNLPQKFLSD AVQDLFPGQA IEKNEFLSHD NQKCDEDKHH TTDSASWIRS GTLSPEIFEK STIDSNENRR HNQWKNSFHP LTTRSNSIMD SFCVQQAEDC LSEKSRLNRS SVSKEVFLSL PQPNNSDWIQ GHTRKEMGQS LDSANTSFTA ILSSPDGELV DVACEDLELY VSRNNDMLTP TPDSSPRSTS SPSQSKNGSF TPRTANILKP LMSPPSREEI MATLLDHDLS ETIYQEPFCS NPSDVPEKPR EIGGRLLMVE TRLANDLAEF EGDFSLEGLR LWKTAFSAMT QNPRPGSPLR SGQGVVNKGS SNSPKMVEDK KIVIMPCKCA PSRQLVQVWL QAKEEYERSK KLPKTKPTGV VKSAENFSSS VNPDDKPVVP PKMDVSPCIL PTTAHTKEDV DNSQIALQAP TTGCSQTASE SQMLPPVASA SDPEKDEDDD DNYYISYSSP DSPVIPPWQQ PISPDSKALN GDDRPSSPVE ELPSLAFENF LKPIKDGIQK SPCSEPQEPL VISPINTRAR TGKCESLCFH STPIIQRKLL ERLPEAPGLS PLSTEPKTQK LSNKKGSNTD TLRRVLLTQA KNQFAAVNTP QKETSQIDGP SLNNTYGFKV SIQNLQEAKA LHEIQNLTLI SVELHARTRR DLEPDPEFDP ICALFYCISS DTPLPDTEKT ELTGVIVIDK DKTVFSQDIR YQTPLLIRSG ITGLEVTYAA DEKALFHEIA NIIKRYDPDI LLGYEIQMHS WGYLLQRAAA LSIDLCRMIS RVPDDKIENR FAAERDEYGS YTMSEINIVG RITLNLWRIM RNEVALTNYT FENVSFHVLH QRFPLFTFRV LSDWFDNKTD LYRWKMVDHY VSRVRGNLQM LEQLDLIGKT SEMARLFGIQ FLHVLTRGSQ YRVESMMLRI AKPMNYIPVT PSVQQRSQMR APQCVPLIME PESRFYSNSV LVLDFQSLYP SIVIAYNYCF STCLGHVENL GKYDEFKFGC TSLRVPPDLL YQVRHDITVS PNGVAFVKPS VRKGVLPRML EEILKTRFMV KQSMKAYKQD RALSRMLDAR QLGLKLIANV TFGYTSANFS GRMPCIEVGD SIVHKARETL ERAIKLVNDT KKWGARVVYG DTDSMFVLLK GATKEQSFKI GQEIAEAVTA TNPKPVKLKF EKVYLPCVLQ TKKRYVGYMY ETLDQKDPVF DAKGIETVRR DSCPAVSKIL ERSLKLLFET RDISLIKQYV QRQCMKLLEG KASIQDFIFA KEYRGSFSYK PGACVPALEL TRKMLTYDRR SEPQVGERVP YVIIYGTPGV PLIQLVRRPV EVLQDPTLRL NATYYITKQI LPPLARIFSL IGIDVFSWYH ELPRIHKATS SSRSEPEGRK GTISQYFTTL HCPVCDDLTQ HGICSKCRSQ PQHVAVILNQ EIRELERQQE QLVKICKNCT GCFDRHIPCV SLNCPVLFKL SRVNRELSKA PYLRQLLDQF
Genular Protein ID: 1640975338
Symbol: Q9UG47_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 323
- Mass: 37386
- Checksum: 30A662AE83F6F68B
- Sequence:
MTSSLPYFIF NPPSMFVLLK GATKEQSFKI GQEIAEAVTA TNPKPVKLKF EKVYLPCVLQ TKKRYVGYMY ETLDQKDPVF DAKGIETVRR DSCPAVSKIL ERSLKLLFET RDISLIKQYV QRQCMKLLEG KASIQDFIFA KEYRGSFSYK PGACVPALEL TRKMLTYDRR SEPQVGERVP YVIIYGTPGV PLIQLVRRPV EVLQDPTLRL NATYYITKQI LPPLARIFSL IGIDVFSWYH ELPRGFIAAL FTIAKTWNQP KCPSMIDWIK KMWHIYTMEY YAAIKKDEFM SFAGTWMKLE TIILSKLSQG QKTKHRLFSL IDP