Gene RPL36AL - ENSG00000165502 | NCBI Gene ID: 6166

Details for: RPL36AL

Gene ID: 6166

Symbol: RPL36AL

Ensembl ID: ENSG00000165502

Description: ribosomal protein L36a like

Associated with

Axon guidance
(R-HSA-422475)
Cap-dependent translation initiation
(R-HSA-72737)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Eukaryotic translation elongation
(R-HSA-156842)
Eukaryotic translation initiation
(R-HSA-72613)
Eukaryotic translation termination
(R-HSA-72764)
Formation of a pool of free 40s subunits
(R-HSA-72689)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-HSA-72706)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
L13a-mediated translational silencing of ceruloplasmin expression
(R-HSA-156827)
Major pathway of rrna processing in the nucleolus and cytosol
(R-HSA-6791226)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of proteins
(R-HSA-392499)
Metabolism of rna
(R-HSA-8953854)
Nervous system development
(R-HSA-9675108)
Nonsense-mediated decay (nmd)
(R-HSA-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-HSA-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-HSA-975956)
Peptide chain elongation
(R-HSA-156902)
Regulation of expression of slits and robos
(R-HSA-9010553)
Response of eif2ak4 (gcn2) to amino acid deficiency
(R-HSA-9633012)
Rrna processing
(R-HSA-72312)
Rrna processing in the nucleus and cytosol
(R-HSA-8868773)
Selenoamino acid metabolism
(R-HSA-2408522)
Selenocysteine synthesis
(R-HSA-2408557)
Signaling by robo receptors
(R-HSA-376176)
Srp-dependent cotranslational protein targeting to membrane
(R-HSA-1799339)
Viral infection pathways
(R-HSA-9824446)
Viral mrna translation
(R-HSA-192823)
Cytosol
(GO:0005829)
Cytosolic large ribosomal subunit
(GO:0022625)
Endoplasmic reticulum
(GO:0005783)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Structural constituent of ribosome
(GO:0003735)
Translation
(GO:0006412)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 4.95
Marker Score: 3874.5
Cell Name: mature T cell (CL0002419)
Fold Change: 4.95
Marker Score: 48997.5
Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 4.68
Marker Score: 22999
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 4.55
Marker Score: 154724.5
Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 4.38
Marker Score: 12790
Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 4.38
Marker Score: 13822
Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 4.25
Marker Score: 224966
Cell Name: malignant cell (CL0001064)
Fold Change: 4.22
Marker Score: 56754.5
Cell Name: IgA plasma cell (CL0000987)
Fold Change: 4.21
Marker Score: 3584
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 4.12
Marker Score: 10053.5
Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
Fold Change: 4.11
Marker Score: 7043
Cell Name: cord blood hematopoietic stem cell (CL2000095)
Fold Change: 4.08
Marker Score: 3079.5
Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: 4.02
Marker Score: 2076
Cell Name: blood cell (CL0000081)
Fold Change: 4.02
Marker Score: 46743
Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 3.99
Marker Score: 2898
Cell Name: elicited macrophage (CL0000861)
Fold Change: 3.99
Marker Score: 24254
Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 3.99
Marker Score: 11179
Cell Name: epithelial cell of exocrine pancreas (CL1001433)
Fold Change: 3.95
Marker Score: 2227.5
Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 3.94
Marker Score: 10892
Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 3.93
Marker Score: 3354
Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 3.92
Marker Score: 16825.5
Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: 3.89
Marker Score: 1999.5
Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 3.83
Marker Score: 4091
Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 3.83
Marker Score: 3697
Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 3.82
Marker Score: 2240
Cell Name: naive B cell (CL0000788)
Fold Change: 3.8
Marker Score: 3390.5
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 3.79
Marker Score: 211889.5
Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 3.78
Marker Score: 4919
Cell Name: renal intercalated cell (CL0005010)
Fold Change: 3.73
Marker Score: 1990.5
Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 3.73
Marker Score: 5488
Cell Name: type I NK T cell (CL0000921)
Fold Change: 3.72
Marker Score: 2920.5
Cell Name: supporting cell (CL0000630)
Fold Change: 3.68
Marker Score: 6921
Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 3.68
Marker Score: 3625
Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 3.67
Marker Score: 23399
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 3.66
Marker Score: 8340
Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 3.63
Marker Score: 5589
Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 3.62
Marker Score: 8826
Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 3.6
Marker Score: 2411
Cell Name: germinal center B cell (CL0000844)
Fold Change: 3.59
Marker Score: 2184
Cell Name: radial glial cell (CL0000681)
Fold Change: 3.58
Marker Score: 1319
Cell Name: naive T cell (CL0000898)
Fold Change: 3.55
Marker Score: 2286
Cell Name: intraepithelial lymphocyte (CL0002496)
Fold Change: 3.55
Marker Score: 3943
Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 3.55
Marker Score: 3699
Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 3.51
Marker Score: 2364
Cell Name: type II pneumocyte (CL0002063)
Fold Change: 3.51
Marker Score: 22885
Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 3.5
Marker Score: 3116
Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 3.49
Marker Score: 2936
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 3.48
Marker Score: 832
Cell Name: basophil (CL0000767)
Fold Change: 3.48
Marker Score: 1651
Cell Name: theca cell (CL0000503)
Fold Change: 3.47
Marker Score: 2487
Cell Name: lung secretory cell (CL1000272)
Fold Change: 3.47
Marker Score: 3092
Cell Name: chondrocyte (CL0000138)
Fold Change: 3.46
Marker Score: 1557
Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 3.45
Marker Score: 3032
Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 3.42
Marker Score: 7167.5
Cell Name: epithelial cell (CL0000066)
Fold Change: 3.4
Marker Score: 5415
Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 3.4
Marker Score: 1555
Cell Name: class switched memory B cell (CL0000972)
Fold Change: 3.4
Marker Score: 3196
Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
Fold Change: 3.39
Marker Score: 1870
Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 3.37
Marker Score: 3156
Cell Name: memory B cell (CL0000787)
Fold Change: 3.37
Marker Score: 2550
Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 3.37
Marker Score: 1401.5
Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 3.35
Marker Score: 5496.5
Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 3.35
Marker Score: 2379
Cell Name: club cell (CL0000158)
Fold Change: 3.34
Marker Score: 3893.5
Cell Name: cell in vitro (CL0001034)
Fold Change: 3.31
Marker Score: 114784
Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
Fold Change: 3.31
Marker Score: 1077
Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 3.31
Marker Score: 17372
Cell Name: exhausted T cell (CL0011025)
Fold Change: 3.3
Marker Score: 1901
Cell Name: regulatory T cell (CL0000815)
Fold Change: 3.3
Marker Score: 3654
Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 3.29
Marker Score: 2377
Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 3.27
Marker Score: 2579
Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 3.27
Marker Score: 1634
Cell Name: memory T cell (CL0000813)
Fold Change: 3.25
Marker Score: 1395
Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 3.24
Marker Score: 2650.5
Cell Name: T follicular helper cell (CL0002038)
Fold Change: 3.23
Marker Score: 2685
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 3.23
Marker Score: 12453
Cell Name: memory regulatory T cell (CL0002678)
Fold Change: 3.23
Marker Score: 1126
Cell Name: mesodermal cell (CL0000222)
Fold Change: 3.22
Marker Score: 42526
Cell Name: serous secreting cell (CL0000313)
Fold Change: 3.22
Marker Score: 1285
Cell Name: unswitched memory B cell (CL0000970)
Fold Change: 3.21
Marker Score: 1881
Cell Name: mucous neck cell (CL0000651)
Fold Change: 3.2
Marker Score: 7262
Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 3.19
Marker Score: 8554.5
Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 3.18
Marker Score: 23674
Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 3.18
Marker Score: 1095
Cell Name: smooth muscle cell (CL0000192)
Fold Change: 3.17
Marker Score: 2083
Cell Name: lung macrophage (CL1001603)
Fold Change: 3.16
Marker Score: 3617.5
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 3.16
Marker Score: 24638
Cell Name: granulocyte (CL0000094)
Fold Change: 3.14
Marker Score: 1409
Cell Name: Kupffer cell (CL0000091)
Fold Change: 3.14
Marker Score: 3136.5
Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 3.13
Marker Score: 11125
Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
Fold Change: 3.12
Marker Score: 2754
Cell Name: reticular cell (CL0000432)
Fold Change: 3.12
Marker Score: 1137
Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 3.11
Marker Score: 819
Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 3.11
Marker Score: 1608
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 3.1
Marker Score: 20150.5
Cell Name: centroblast (CL0009112)
Fold Change: 3.09
Marker Score: 1522
Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 3.09
Marker Score: 7587
Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 3.08
Marker Score: 5509
Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 3.08
Marker Score: 1330
Cell Name: fibroblast of breast (CL4006000)
Fold Change: 3.08
Marker Score: 1756.5

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**Key characteristics:** - RPL36AL is a large protein (60S) that is found in the cytoplasm. - It is a member of the ribosomal protein L36 family of proteins. - RPL36AL is required for the initiation of translation. - It is involved in the processing of mRNA, including the removal of a processing signal from the 5' cap. - It is also involved in the translation of mRNA into proteins. **Pathways and functions:** - RPL36AL is involved in the initiation of translation. - It is a key component of the ribosome, which is responsible for protein synthesis. - It is also involved in the processing of mRNA, including the removal of a processing signal from the 5' cap. - It is involved in the translation of mRNA into proteins. **Clinical significance:** - Mutations in RPL36AL have been linked to several human diseases, including cancer and neurodegenerative disorders. - These mutations can lead to the production of a protein that is misfolded or truncated, which can disrupt protein synthesis and lead to disease. - Research on RPL36AL is ongoing, and new insights into the role of this protein in human health and disease are expected to emerge in the future.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

60S ribosomal protein L36a-like

Genular Protein ID: 656281534

Symbol: RL36L_HUMAN

Name: 60S ribosomal protein L36a-like

UniProtKB Accession Codes:

Q969Q0 Q3B7A5

Database IDs:

Citations:

PubMed ID: 3542712

Title: Characterisation of an mRNA encoding a human ribosomal protein homologous to the yeast L44 ribosomal protein.

PubMed ID: 3542712

DOI: 10.1016/0378-1119(86)90253-2

PubMed ID: 12490704

Title: Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes.

PubMed ID: 12490704

DOI: 10.1093/nar/gkf696

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

Length: 106
Mass: 12469
Checksum: 9C0E08264A578D31
Sequence:

MVNVPKTRRT FCKKCGKHQP HKVTQYKKGK DSLYAQGRRR YDRKQSGYGG QTKPIFRKKA 
KTTKKIVLRL ECVEPNCRSK RMLAIKRCKH FELGGDKKRK GQVIQF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.

Details for: RPL36AL

Associated with

Cells (max top 100)

Other Information

Characterisation of an mRNA encoding a human ribosomal protein homologous to the yeast L44 ribosomal protein. PubMed ID: 3542712

Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes. PubMed ID: 12490704

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Initial characterization of the human central proteome. PubMed ID: 21269460

Database document:

PubMed ID: 3542712

PubMed ID: 12490704

PubMed ID: 15489334

PubMed ID: 21269460