Gene RPS6 - ENSG00000137154 | NCBI Gene ID: 6194

Details for: RPS6

Gene ID: 6194

Symbol: RPS6

Ensembl ID: ENSG00000137154

Description: ribosomal protein S6

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-HSA-72662)
Axon guidance
(R-HSA-422475)
Cap-dependent translation initiation
(R-HSA-72737)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Eukaryotic translation elongation
(R-HSA-156842)
Eukaryotic translation initiation
(R-HSA-72613)
Eukaryotic translation termination
(R-HSA-72764)
Formation of a pool of free 40s subunits
(R-HSA-72689)
Formation of the ternary complex, and subsequently, the 43s complex
(R-HSA-72695)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(R-HSA-163841)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-HSA-72706)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
L13a-mediated translational silencing of ceruloplasmin expression
(R-HSA-156827)
Major pathway of rrna processing in the nucleolus and cytosol
(R-HSA-6791226)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of proteins
(R-HSA-392499)
Metabolism of rna
(R-HSA-8953854)
Mtorc1-mediated signalling
(R-HSA-166208)
Mtor signalling
(R-HSA-165159)
Nervous system development
(R-HSA-9675108)
Nonsense-mediated decay (nmd)
(R-HSA-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-HSA-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-HSA-975956)
Nuclear events stimulated by alk signaling in cancer
(R-HSA-9725371)
Peptide chain elongation
(R-HSA-156902)
Post-translational protein modification
(R-HSA-597592)
Protein hydroxylation
(R-HSA-9629569)
Regulation of expression of slits and robos
(R-HSA-9010553)
Response of eif2ak4 (gcn2) to amino acid deficiency
(R-HSA-9633012)
Ribosomal scanning and start codon recognition
(R-HSA-72702)
Rrna modification in the nucleus and cytosol
(R-HSA-6790901)
Rrna processing in the nucleus and cytosol
(R-HSA-8868773)
Sars-cov-1 infection
(R-HSA-9678108)
Sars-cov-1 modulates host translation machinery
(R-HSA-9735869)
Sars-cov-1-host interactions
(R-HSA-9692914)
Sars-cov-2 infection
(R-HSA-9694516)
Sars-cov-2 modulates host translation machinery
(R-HSA-9754678)
Sars-cov-2-host interactions
(R-HSA-9705683)
Sars-cov infections
(R-HSA-9679506)
Selenoamino acid metabolism
(R-HSA-2408522)
Selenocysteine synthesis
(R-HSA-2408557)
Signaling by alk fusions and activated point mutants
(R-HSA-9725370)
Signaling by alk in cancer
(R-HSA-9700206)
Signaling by robo receptors
(R-HSA-376176)
Signal transduction
(R-HSA-162582)
Srp-dependent cotranslational protein targeting to membrane
(R-HSA-1799339)
Translation initiation complex formation
(R-HSA-72649)
Viral infection pathways
(R-HSA-9824446)
Viral mrna translation
(R-HSA-192823)
Cell body
(GO:0044297)
Cytoplasm
(GO:0005737)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Cytoplasmic translation
(GO:0002181)
Cytosol
(GO:0005829)
Cytosolic ribosome
(GO:0022626)
Cytosolic small ribosomal subunit
(GO:0022627)
Dendrite
(GO:0030425)
Endoplasmic reticulum
(GO:0005783)
Glucose homeostasis
(GO:0042593)
Membrane
(GO:0016020)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cell population proliferation
(GO:0008284)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Ribonucleoprotein complex
(GO:1990904)
Ribosomal small subunit biogenesis
(GO:0042274)
Rna binding
(GO:0003723)
Rrna processing
(GO:0006364)
Small-subunit processome
(GO:0032040)
Small ribosomal subunit
(GO:0015935)
Structural constituent of ribosome
(GO:0003735)
Tor signaling
(GO:0031929)
Translation
(GO:0006412)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: epithelial cell of exocrine pancreas (CL1001433)
Fold Change: 8.44
Marker Score: 4756
Cell Name: cord blood hematopoietic stem cell (CL2000095)
Fold Change: 6.73
Marker Score: 5080
Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 6.19
Marker Score: 25791.5
Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 6.14
Marker Score: 30151
Cell Name: endocardial cell (CL0002350)
Fold Change: 6
Marker Score: 3391
Cell Name: malignant cell (CL0001064)
Fold Change: 5.78
Marker Score: 77677
Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 5.69
Marker Score: 11927
Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 5.57
Marker Score: 4041
Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: 5.48
Marker Score: 2817
Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: 5.46
Marker Score: 2817
Cell Name: acinar cell (CL0000622)
Fold Change: 5.45
Marker Score: 3843
Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 5.44
Marker Score: 7090
Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 5.37
Marker Score: 15676
Cell Name: naive T cell (CL0000898)
Fold Change: 5.34
Marker Score: 3437
Cell Name: radial glial cell (CL0000681)
Fold Change: 5.31
Marker Score: 1959
Cell Name: mature T cell (CL0002419)
Fold Change: 5.31
Marker Score: 52603
Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: 5.21
Marker Score: 3961
Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
Fold Change: 5.16
Marker Score: 8856
Cell Name: theca cell (CL0000503)
Fold Change: 5.1
Marker Score: 3655
Cell Name: IgA plasma cell (CL0000987)
Fold Change: 5.04
Marker Score: 4290
Cell Name: naive B cell (CL0000788)
Fold Change: 5.02
Marker Score: 4486.5
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 4.98
Marker Score: 169561
Cell Name: taste receptor cell (CL0000209)
Fold Change: 4.9
Marker Score: 4235
Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 4.81
Marker Score: 15191
Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 4.74
Marker Score: 250859
Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 4.71
Marker Score: 24762
Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 4.68
Marker Score: 7210
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 4.68
Marker Score: 1118
Cell Name: memory T cell (CL0000813)
Fold Change: 4.63
Marker Score: 1991
Cell Name: intraepithelial lymphocyte (CL0002496)
Fold Change: 4.53
Marker Score: 5038.5
Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
Fold Change: 4.5
Marker Score: 1461.5
Cell Name: mesodermal cell (CL0000222)
Fold Change: 4.47
Marker Score: 59015
Cell Name: germinal center B cell (CL0000844)
Fold Change: 4.39
Marker Score: 2672
Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 4.37
Marker Score: 11716
Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 4.37
Marker Score: 11108
Cell Name: glial cell (CL0000125)
Fold Change: 4.36
Marker Score: 4796.5
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 4.36
Marker Score: 77352.5
Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 4.35
Marker Score: 15449
Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 4.33
Marker Score: 27612
Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 4.31
Marker Score: 11912
Cell Name: endocrine cell (CL0000163)
Fold Change: 4.31
Marker Score: 2228
Cell Name: elicited macrophage (CL0000861)
Fold Change: 4.29
Marker Score: 26047
Cell Name: chondrocyte (CL0000138)
Fold Change: 4.29
Marker Score: 1929
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.26
Marker Score: 238089
Cell Name: blood cell (CL0000081)
Fold Change: 4.25
Marker Score: 49448
Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 4.24
Marker Score: 6168
Cell Name: renal intercalated cell (CL0005010)
Fold Change: 4.23
Marker Score: 2258
Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 4.22
Marker Score: 11851
Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 4.22
Marker Score: 2474
Cell Name: club cell (CL0000158)
Fold Change: 4.22
Marker Score: 4921
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 4.21
Marker Score: 10278
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.14
Marker Score: 9439
Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 4.13
Marker Score: 947
Cell Name: endothelial cell (CL0000115)
Fold Change: 4.11
Marker Score: 3682
Cell Name: type II pneumocyte (CL0002063)
Fold Change: 4.1
Marker Score: 26725
Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 4.09
Marker Score: 3953.5
Cell Name: myofibroblast cell (CL0000186)
Fold Change: 4.09
Marker Score: 5044
Cell Name: type I NK T cell (CL0000921)
Fold Change: 4.08
Marker Score: 3202
Cell Name: supporting cell (CL0000630)
Fold Change: 4.08
Marker Score: 7660
Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 4.07
Marker Score: 17452
Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 4.07
Marker Score: 3466.5
Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 4.05
Marker Score: 9888
Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 4.04
Marker Score: 4317
Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 4.04
Marker Score: 5949
Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 4.03
Marker Score: 10027
Cell Name: hepatocyte (CL0000182)
Fold Change: 4
Marker Score: 2734
Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 4
Marker Score: 4300
Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 3.99
Marker Score: 29717
Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 3.99
Marker Score: 3550
Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 3.98
Marker Score: 3923
Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 3.97
Marker Score: 4138.5
Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
Fold Change: 3.96
Marker Score: 3495
Cell Name: starburst amacrine cell (CL0004232)
Fold Change: 3.96
Marker Score: 1123
Cell Name: reticular cell (CL0000432)
Fold Change: 3.94
Marker Score: 1437.5
Cell Name: ventricular cardiac muscle cell (CL2000046)
Fold Change: 3.93
Marker Score: 1631
Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 3.93
Marker Score: 9902
Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 3.92
Marker Score: 2786
Cell Name: stromal cell (CL0000499)
Fold Change: 3.91
Marker Score: 4582
Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 3.91
Marker Score: 2629
Cell Name: endothelial tip cell (CL0000704)
Fold Change: 3.91
Marker Score: 909
Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 3.9
Marker Score: 3197
Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
Fold Change: 3.89
Marker Score: 2148
Cell Name: granulocyte (CL0000094)
Fold Change: 3.89
Marker Score: 1742.5
Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 3.88
Marker Score: 2011.5
Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 3.88
Marker Score: 1021
Cell Name: paneth cell (CL0000510)
Fold Change: 3.87
Marker Score: 2694
Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 3.86
Marker Score: 3638
Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 3.84
Marker Score: 1096
Cell Name: class switched memory B cell (CL0000972)
Fold Change: 3.83
Marker Score: 3603
Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 3.83
Marker Score: 3364
Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 3.83
Marker Score: 2901
Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 3.82
Marker Score: 3291
Cell Name: regulatory T cell (CL0000815)
Fold Change: 3.82
Marker Score: 4227
Cell Name: columnar/cuboidal epithelial cell (CL0000075)
Fold Change: 3.81
Marker Score: 1010
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.81
Marker Score: 4601
Cell Name: meningeal macrophage (CL0000879)
Fold Change: 3.81
Marker Score: 1073
Cell Name: fibroblast (CL0000057)
Fold Change: 3.81
Marker Score: 3677
Cell Name: Schwann cell precursor (CL0002375)
Fold Change: 3.8
Marker Score: 946
Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 3.8
Marker Score: 1249.5
Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 3.78
Marker Score: 1213

Hover over a box to see details here...

**Key characteristics:** - It is a large protein with a molecular weight of approximately 120 kDa. - It is expressed in a variety of cell types, including epithelial cells, hematopoietic stem cells, myoepithelial cells, and antigen presenting cells. - It is a key regulator of protein translation by binding to the 5' cap of mRNA and promoting translation initiation. - It is also involved in stress response and inflammation. **Pathways and functions:** - RS6 is involved in the initiation of protein translation. - It is a key regulator of the unfolded protein response (UPR), a cellular pathway that is activated in response to stress conditions. - It is also involved in the regulation of apoptosis, cell cycle regulation, and inflammation. - It plays a role in the development and function of immune cells, including dendritic cells and T cells. - It is also involved in the regulation of epithelial cell function. **Clinical significance:** - Mutations in the RPS6 gene have been linked to a number of human diseases, including cancer and metabolic disorders. - Targeting RS6 has been explored as a therapeutic strategy for these diseases. - In some cases, knockdown of RS6 has been shown to be effective in treating cancer. **Conclusion:** RS6 is a critical regulator of cellular metabolism and growth. Its expression and activity are tightly regulated to ensure that cells are properly translated and maintained. Mutations in the RPS6 gene can lead to a variety of human diseases, highlighting its important role in human health.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Phosphoprotein NP33

Genular Protein ID: 3470706467

Symbol: RS6_HUMAN

Name: Phosphoprotein NP33

UniProtKB Accession Codes:

P62753 P08227 P10660 Q4VBY7 Q8N6Z7

Database IDs:

Citations:

PubMed ID: 2840355

Title: Isolation and characterization of cloned cDNAs that code for human ribosomal protein S6.

PubMed ID: 2840355

DOI: 10.1016/0378-1119(88)90414-3

PubMed ID: 3279029

Title: The primary structure of the human ribosomal protein S6 derived from a cloned cDNA.

PubMed ID: 3279029

DOI: 10.1016/s0021-9258(18)68900-8

PubMed ID: 1301164

Title: The organization of the intron-containing human S6 ribosomal protein (rpS6) gene and determination of its location at chromosome 9p21.

PubMed ID: 1301164

DOI: 10.1093/hmg/1.8.565

PubMed ID: 1446836

Title: The human ribosomal protein S6 gene: isolation, primary structure and location in chromosome 9.

PubMed ID: 1446836

DOI: 10.1016/0378-1119(92)90149-j

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706699

Title: Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.

PubMed ID: 8706699

DOI: 10.1111/j.1432-1033.1996.0144u.x

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17360704

Title: RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.

PubMed ID: 17360704

DOI: 10.1074/jbc.m700906200

PubMed ID: 17220279

Title: hDREF regulates cell proliferation and expression of ribosomal protein genes.

PubMed ID: 17220279

DOI: 10.1128/mcb.01462-06

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18974095

Title: Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling.

PubMed ID: 18974095

DOI: 10.1074/jbc.m805165200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21418524

Title: Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN.

PubMed ID: 21418524

DOI: 10.1111/j.1742-4658.2011.08100.x

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24524803

Title: A new system for naming ribosomal proteins.

PubMed ID: 24524803

DOI: 10.1016/j.sbi.2014.01.002

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 29563586

Title: JMJD5 is a human L-arginyl C-3 hydroxylase.

PubMed ID: 29563586

DOI: 10.1038/s41467-018-03410-w

PubMed ID: 34314702

Title: Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers.

PubMed ID: 34314702

DOI: 10.1016/j.cell.2021.07.005

PubMed ID: 23636399

Title: Structures of the human and Drosophila 80S ribosome.

PubMed ID: 23636399

DOI: 10.1038/nature12104

PubMed ID: 34516797

Title: Nucleolar maturation of the human small subunit processome.

PubMed ID: 34516797

DOI: 10.1126/science.abj5338

Sequence Information:

Length: 249
Mass: 28681
Checksum: A61E435884E636AE
Sequence:

MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV RISGGNDKQG 
FPMKQGVLTH GRVRLLLSKG HSCYRPRRTG ERKRKSVRGC IVDANLSVLN LVIVKKGEKD 
IPGLTDTTVP RRLGPKRASR IRKLFNLSKE DDVRQYVVRK PLNKEGKKPR TKAPKIQRLV 
TPRVLQHKRR RIALKKQRTK KNKEEAAEYA KLLAKRMKEA KEKRQEQIAK RRRLSSLRAS 
TSKSESSQK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.

Details for: RPS6

Associated with

Cells (max top 100)

Other Information

Isolation and characterization of cloned cDNAs that code for human ribosomal protein S6. PubMed ID: 2840355

The primary structure of the human ribosomal protein S6 derived from a cloned cDNA. PubMed ID: 3279029

The organization of the intron-containing human S6 ribosomal protein (rpS6) gene and determination of its location at chromosome 9p21. PubMed ID: 1301164

The human ribosomal protein S6 gene: isolation, primary structure and location in chromosome 9. PubMed ID: 1446836

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. PubMed ID: 8706699

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. PubMed ID: 17360704

hDREF regulates cell proliferation and expression of ribosomal protein genes. PubMed ID: 17220279

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. PubMed ID: 18691976

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling. PubMed ID: 18974095

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN. PubMed ID: 21418524

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

A new system for naming ribosomal proteins. PubMed ID: 24524803

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

JMJD5 is a human L-arginyl C-3 hydroxylase. PubMed ID: 29563586

Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers. PubMed ID: 34314702

Structures of the human and Drosophila 80S ribosome. PubMed ID: 23636399

Nucleolar maturation of the human small subunit processome. PubMed ID: 34516797