RPS7 | ENSG00000171863 | NCBI 6201

Details for: RPS7

Gene ID: 6201

Symbol: RPS7

Ensembl ID: ENSG00000171863

Description: ribosomal protein S7

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-HSA-72662)
Axon guidance
(R-HSA-422475)
Cap-dependent translation initiation
(R-HSA-72737)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Eukaryotic translation elongation
(R-HSA-156842)
Eukaryotic translation initiation
(R-HSA-72613)
Eukaryotic translation termination
(R-HSA-72764)
Formation of a pool of free 40s subunits
(R-HSA-72689)
Formation of the ternary complex, and subsequently, the 43s complex
(R-HSA-72695)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-HSA-72706)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
L13a-mediated translational silencing of ceruloplasmin expression
(R-HSA-156827)
Major pathway of rrna processing in the nucleolus and cytosol
(R-HSA-6791226)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of proteins
(R-HSA-392499)
Metabolism of rna
(R-HSA-8953854)
Nervous system development
(R-HSA-9675108)
Nonsense-mediated decay (nmd)
(R-HSA-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-HSA-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-HSA-975956)
Peptide chain elongation
(R-HSA-156902)
Regulation of expression of slits and robos
(R-HSA-9010553)
Response of eif2ak4 (gcn2) to amino acid deficiency
(R-HSA-9633012)
Ribosomal scanning and start codon recognition
(R-HSA-72702)
Rrna modification in the nucleus and cytosol
(R-HSA-6790901)
Rrna processing in the nucleus and cytosol
(R-HSA-8868773)
Sars-cov-1 infection
(R-HSA-9678108)
Sars-cov-1 modulates host translation machinery
(R-HSA-9735869)
Sars-cov-1-host interactions
(R-HSA-9692914)
Sars-cov-2 infection
(R-HSA-9694516)
Sars-cov-2 modulates host translation machinery
(R-HSA-9754678)
Sars-cov-2-host interactions
(R-HSA-9705683)
Sars-cov infections
(R-HSA-9679506)
Selenoamino acid metabolism
(R-HSA-2408522)
Selenocysteine synthesis
(R-HSA-2408557)
Signaling by robo receptors
(R-HSA-376176)
Srp-dependent cotranslational protein targeting to membrane
(R-HSA-1799339)
Translation initiation complex formation
(R-HSA-72649)
Viral infection pathways
(R-HSA-9824446)
Viral mrna translation
(R-HSA-192823)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Cytoplasmic translation
(GO:0002181)
Cytosol
(GO:0005829)
Cytosolic ribosome
(GO:0022626)
Cytosolic small ribosomal subunit
(GO:0022627)
Endoplasmic reticulum
(GO:0005783)
Focal adhesion
(GO:0005925)
Membrane
(GO:0016020)
Mrna 3'-utr binding
(GO:0003730)
Mrna 5'-utr binding
(GO:0048027)
Negative regulation of ubiquitin-dependent protein catabolic process
(GO:2000059)
Negative regulation of ubiquitin protein ligase activity
(GO:1904667)
Neural crest cell differentiation
(GO:0014033)
Neural tube closure
(GO:0001843)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
(GO:1902255)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Protein stabilization
(GO:0050821)
Ribonucleoprotein complex
(GO:1990904)
Ribosomal small subunit biogenesis
(GO:0042274)
Ribosome
(GO:0005840)
Rna binding
(GO:0003723)
Rrna processing
(GO:0006364)
Small-subunit processome
(GO:0032040)
Structural constituent of ribosome
(GO:0003735)
Synapse
(GO:0045202)
Translation
(GO:0006412)
Ubiquitin ligase inhibitor activity
(GO:1990948)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: embryonic stem cell (CL0002322)
Fold Change: 702.0553
Cell Significance Index: -289.2100
Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 585.3775
Cell Significance Index: -276.3700
Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 558.3121
Cell Significance Index: -287.1900
Cell Name: ileal goblet cell (CL1000326)
Fold Change: 413.4141
Cell Significance Index: -277.4100
Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 35.7428
Cell Significance Index: -95.7500
Cell Name: pro-T cell (CL0000827)
Fold Change: 17.8725
Cell Significance Index: 456.5900
Cell Name: theca cell (CL0000503)
Fold Change: 16.1208
Cell Significance Index: 94.7100
Cell Name: abnormal cell (CL0001061)
Fold Change: 15.4331
Cell Significance Index: 1576.4900
Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 15.2669
Cell Significance Index: 408.3800
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 13.9337
Cell Significance Index: 178.4500
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 12.6013
Cell Significance Index: 592.2500
Cell Name: granulosa cell (CL0000501)
Fold Change: 11.6243
Cell Significance Index: 305.6600
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 10.7029
Cell Significance Index: 371.9200
Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 9.7518
Cell Significance Index: 204.1200
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 9.6254
Cell Significance Index: 275.9200
Cell Name: lactocyte (CL0002325)
Fold Change: 9.2077
Cell Significance Index: 1189.5700
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 9.2073
Cell Significance Index: 1264.4200
Cell Name: sebum secreting cell (CL0000317)
Fold Change: 8.8803
Cell Significance Index: 628.0500
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 8.7820
Cell Significance Index: 155.1900
Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 8.7637
Cell Significance Index: 99.5600
Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 8.4249
Cell Significance Index: 91.5900
Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 8.3691
Cell Significance Index: 986.9700
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 7.9271
Cell Significance Index: 974.7100
Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 7.8789
Cell Significance Index: 3483.4600
Cell Name: cell in vitro (CL0001034)
Fold Change: 7.7920
Cell Significance Index: 4255.4100
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 7.7073
Cell Significance Index: 1389.3900
Cell Name: peg cell (CL4033014)
Fold Change: 7.3646
Cell Significance Index: 170.1500
Cell Name: early pro-B cell (CL0002046)
Fold Change: 7.0260
Cell Significance Index: 453.2900
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 6.9629
Cell Significance Index: 518.9400
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 6.1074
Cell Significance Index: 112.8800
Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 6.0753
Cell Significance Index: 178.4300
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 5.8819
Cell Significance Index: 160.1000
Cell Name: odontoblast (CL0000060)
Fold Change: 5.0486
Cell Significance Index: 647.2000
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.4629
Cell Significance Index: 208.0800
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 4.0954
Cell Significance Index: 699.3200
Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 3.9875
Cell Significance Index: 24.5400
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.6841
Cell Significance Index: 193.4300
Cell Name: neoplastic cell (CL0001063)
Fold Change: 3.2430
Cell Significance Index: 643.5800
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.4366
Cell Significance Index: 65.0600
Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 2.3228
Cell Significance Index: 21.3900
Cell Name: kidney cell (CL1000497)
Fold Change: 2.2269
Cell Significance Index: 17.7800
Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 2.2027
Cell Significance Index: 1667.2500
Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 1.0849
Cell Significance Index: 795.4500
Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8812
Cell Significance Index: 795.6600
Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.7510
Cell Significance Index: 142.9200
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5236
Cell Significance Index: 27.2000
Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 0.4259
Cell Significance Index: 3.6600
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2906
Cell Significance Index: 13.1700
Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1930
Cell Significance Index: 19.0900
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.0960
Cell Significance Index: 27.6200
Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 0.0790
Cell Significance Index: 6.2600
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0410
Cell Significance Index: 8.2300
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0105
Cell Significance Index: 1.7000
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0792
Cell Significance Index: -149.1200
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1053
Cell Significance Index: -77.9900
Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1290
Cell Significance Index: -237.9800
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1588
Cell Significance Index: -99.1900
Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1658
Cell Significance Index: -255.1700
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.2295
Cell Significance Index: -129.4200
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.2302
Cell Significance Index: -312.9700
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.2975
Cell Significance Index: -106.7200
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.3405
Cell Significance Index: -216.2700
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.5324
Cell Significance Index: -241.6300
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.5582
Cell Significance Index: -117.5700
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.9190
Cell Significance Index: -57.9200
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -1.1041
Cell Significance Index: -126.4900
Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -1.1074
Cell Significance Index: -126.4100
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -1.3641
Cell Significance Index: -83.8400
Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -1.4201
Cell Significance Index: -8.5800
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -1.4388
Cell Significance Index: -80.7400
Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.5093
Cell Significance Index: -25.2600
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.7262
Cell Significance Index: -250.9300
Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.8180
Cell Significance Index: -31.3400
Cell Name: hepatic pit cell (CL2000054)
Fold Change: -2.0027
Cell Significance Index: -5.3600
Cell Name: gut absorptive cell (CL0000677)
Fold Change: -2.6198
Cell Significance Index: -157.2800
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -2.6234
Cell Significance Index: -273.1600
Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -3.0190
Cell Significance Index: -96.7000
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -3.3584
Cell Significance Index: -257.7200
Cell Name: perivascular cell (CL4033054)
Fold Change: -3.6017
Cell Significance Index: -16.6300
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -3.8355
Cell Significance Index: -257.9000
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -3.9674
Cell Significance Index: -54.1300
Cell Name: retinal rod cell (CL0000604)
Fold Change: -4.1357
Cell Significance Index: -49.3000
Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -4.3329
Cell Significance Index: -265.6500
Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -4.3830
Cell Significance Index: -91.4100
Cell Name: paneth cell of colon (CL0009009)
Fold Change: -4.6710
Cell Significance Index: -69.9900
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -4.9695
Cell Significance Index: -174.6200
Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -5.0113
Cell Significance Index: -85.8800
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -5.4706
Cell Significance Index: -118.5200
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -5.5121
Cell Significance Index: -162.3600
Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -5.6668
Cell Significance Index: -30.9000
Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -6.1216
Cell Significance Index: -51.4200
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -6.3600
Cell Significance Index: -281.3200
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -6.6534
Cell Significance Index: -244.2400
Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -6.8014
Cell Significance Index: -42.2600
Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -7.1433
Cell Significance Index: -55.0600
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -7.1886
Cell Significance Index: -92.5800
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -7.3107
Cell Significance Index: -187.9200
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -7.5910
Cell Significance Index: -287.4500
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -7.6860
Cell Significance Index: -269.2600
Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -7.6915
Cell Significance Index: -251.8200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics** RPS7 is a highly conserved protein, with significant sequence homology across species. It is a small, acidic protein (approximately 115 amino acids) that is localized to the cytosol and cytosolic ribosomes. RPS7 is a key component of the 40S small subunit, interacting with eIF2, eIF4E, and eIF3 to facilitate the binding of mRNA to the ribosome. This protein is also involved in the regulation of gene expression, with studies suggesting its involvement in the positive regulation of gene expression and the negative regulation of ubiquitin-dependent protein catabolic process. **Pathways and Functions** RPS7 is involved in various cellular pathways, including: 1. **Translation initiation**: RPS7 plays a critical role in the initiation of translation, binding to mRNA and facilitating the recruitment of the 43S complex. 2. **Stress response**: RPS7 is involved in the cellular response to stress, including starvation and viral infections. 3. **Viral infection**: RPS7 has been implicated in the modulation of host translation machinery by SARS-CoV-1 and SARS-CoV-2. 4. **Gene expression**: RPS7 is involved in the positive regulation of gene expression and the negative regulation of ubiquitin-dependent protein catabolic process. 5. **Ribosome biogenesis**: RPS7 is involved in the biogenesis of the 40S small subunit and the small-subunit processome. **Clinical Significance** Dysregulation of RPS7 has been implicated in various diseases, including: 1. **Cancer**: RPS7 has been found to be overexpressed in certain types of cancer, including breast and lung cancer. 2. **Infectious diseases**: RPS7 has been implicated in the modulation of host translation machinery by SARS-CoV-1 and SARS-CoV-2. 3. **Neurological disorders**: RPS7 has been found to be involved in the pathogenesis of certain neurological disorders, including Alzheimer's disease and Parkinson's disease. 4. **Metabolic disorders**: RPS7 has been implicated in the regulation of gene expression in metabolic disorders, including diabetes and obesity. In conclusion, RPS7 is a crucial component of the eukaryotic ribosome, playing a pivotal role in the initiation of translation and the regulation of gene expression. Its dysregulation has been implicated in various diseases, highlighting the importance of this protein in maintaining cellular homeostasis. Further research is needed to fully elucidate the functions of RPS7 and its role in disease.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

40S ribosomal protein S7

Genular Protein ID: 3556201778

Symbol: RS7_HUMAN

Name: 40S ribosomal protein S7

UniProtKB Accession Codes:

P62081 P23821 P24818 Q57Z92 Q6IPH1

Database IDs:

Citations:

PubMed ID: 8522193

Title: The human ribosomal protein S7-encoding gene: isolation, structure and localization in 2p25.

PubMed ID: 8522193

DOI: 10.1016/0378-1119(95)00405-u

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706699

Title: Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.

PubMed ID: 8706699

DOI: 10.1111/j.1432-1033.1996.0144u.x

PubMed ID: 9687515

Title: Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells.

PubMed ID: 9687515

DOI: 10.1093/emboj/17.15.4491

PubMed ID: 11823430

Title: Importins fulfill a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains.

PubMed ID: 11823430

DOI: 10.1093/emboj/21.3.377

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 19061985

Title: Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients.

PubMed ID: 19061985

DOI: 10.1016/j.ajhg.2008.11.004

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20873783

Title: Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome.

PubMed ID: 20873783

DOI: 10.1021/pr100562w

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24524803

Title: A new system for naming ribosomal proteins.

PubMed ID: 24524803

DOI: 10.1016/j.sbi.2014.01.002

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 23636399

Title: Structures of the human and Drosophila 80S ribosome.

PubMed ID: 23636399

DOI: 10.1038/nature12104

PubMed ID: 28483520

Title: PPPDE1 is a novel deubiquitinase belonging to a cysteine isopeptidase family.

PubMed ID: 28483520

DOI: 10.1016/j.bbrc.2017.04.161

PubMed ID: 34516797

Title: Nucleolar maturation of the human small subunit processome.

PubMed ID: 34516797

DOI: 10.1126/science.abj5338

Sequence Information:

Length: 194
Mass: 22127
Checksum: E21089929CC061E9
Sequence:

MFSSSAKIVK PNGEKPDEFE SGISQALLEL EMNSDLKAQL RELNITAAKE IEVGGGRKAI 
IIFVPVPQLK SFQKIQVRLV RELEKKFSGK HVVFIAQRRI LPKPTRKSRT KNKQKRPRSR 
TLTAVHDAIL EDLVFPSEIV GKRIRVKLDG SRLIKVHLDK AQQNNVEHKV ETFSGVYKKL 
TGKDVNFEFP EFQL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RPS7

Associated with

Cells (max top 100)

Other Information

The human ribosomal protein S7-encoding gene: isolation, structure and localization in 2p25. PubMed ID: 8522193

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. PubMed ID: 8706699

Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. PubMed ID: 9687515

Importins fulfill a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. PubMed ID: 11823430

Proteomic characterization of the human centrosome by protein correlation profiling. PubMed ID: 14654843

Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients. PubMed ID: 19061985

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome. PubMed ID: 20873783

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

A new system for naming ribosomal proteins. PubMed ID: 24524803

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

Structures of the human and Drosophila 80S ribosome. PubMed ID: 23636399

PPPDE1 is a novel deubiquitinase belonging to a cysteine isopeptidase family. PubMed ID: 28483520

Nucleolar maturation of the human small subunit processome. PubMed ID: 34516797