Details for: RPS24

Gene ID: 6229

Symbol: RPS24

Ensembl ID: ENSG00000138326

Description: ribosomal protein S24

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epithelial cell of exocrine pancreas (CL1001433)
    Fold Change: 6.97
    Marker Score: 3930
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 6.33
    Marker Score: 31075
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 5.73
    Marker Score: 4487
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 5.62
    Marker Score: 11780
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 5.59
    Marker Score: 75088.5
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 5.38
    Marker Score: 2775
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 5.32
    Marker Score: 52696.5
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 5.29
    Marker Score: 15445
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 5.29
    Marker Score: 1951
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 5.19
    Marker Score: 6757
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 5.12
    Marker Score: 3717
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 5.09
    Marker Score: 173156
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 5.08
    Marker Score: 8713
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 5
    Marker Score: 4465.5
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 4.97
    Marker Score: 2552
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 4.96
    Marker Score: 3500.5
  • Cell Name: theca cell (CL0000503)
    Fold Change: 4.9
    Marker Score: 3511
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 4.85
    Marker Score: 15314
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 4.82
    Marker Score: 7426.5
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 4.81
    Marker Score: 25285
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 4.75
    Marker Score: 251035
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 4.66
    Marker Score: 1113
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 4.63
    Marker Score: 12420
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 4.56
    Marker Score: 16207
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 4.53
    Marker Score: 253091
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 4.5
    Marker Score: 59392
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 4.47
    Marker Score: 4969
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 4.45
    Marker Score: 11318
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 4.41
    Marker Score: 26778
  • Cell Name: blood cell (CL0000081)
    Fold Change: 4.39
    Marker Score: 50990
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 4.38
    Marker Score: 3305
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 4.35
    Marker Score: 2649.5
  • Cell Name: memory T cell (CL0000813)
    Fold Change: 4.33
    Marker Score: 1860
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 4.32
    Marker Score: 3735
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 4.29
    Marker Score: 3054
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 4.28
    Marker Score: 11829
  • Cell Name: club cell (CL0000158)
    Fold Change: 4.26
    Marker Score: 4974
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 4.24
    Marker Score: 10351
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 4.24
    Marker Score: 11885
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 4.23
    Marker Score: 10672
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 4.21
    Marker Score: 1370
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 4.18
    Marker Score: 2851
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 4.18
    Marker Score: 2448
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 4.17
    Marker Score: 4031
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 4.16
    Marker Score: 30946
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 4.15
    Marker Score: 3721
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 4.15
    Marker Score: 3157
  • Cell Name: naive T cell (CL0000898)
    Fold Change: 4.15
    Marker Score: 2671.5
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 4.12
    Marker Score: 945
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 4.12
    Marker Score: 9386
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 4.11
    Marker Score: 5073
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 4.11
    Marker Score: 26778
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 4.1
    Marker Score: 10011
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 4.08
    Marker Score: 17511
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 4.08
    Marker Score: 3200
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: 4.07
    Marker Score: 3467
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 4.07
    Marker Score: 3470
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 4.07
    Marker Score: 5988
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 4.04
    Marker Score: 4885
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 4.03
    Marker Score: 3804.5
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 4.02
    Marker Score: 4297
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 4.02
    Marker Score: 10015
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 3.99
    Marker Score: 3552
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 3.99
    Marker Score: 3933
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 3.96
    Marker Score: 7443
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 3.95
    Marker Score: 16467
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 3.95
    Marker Score: 7191
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 3.93
    Marker Score: 3469
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 3.93
    Marker Score: 3216
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 3.9
    Marker Score: 2626
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 3.9
    Marker Score: 3427
  • Cell Name: starburst amacrine cell (CL0004232)
    Fold Change: 3.88
    Marker Score: 1101
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 3.86
    Marker Score: 5615
  • Cell Name: meningeal macrophage (CL0000879)
    Fold Change: 3.86
    Marker Score: 1087
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 3.86
    Marker Score: 4518.5
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 3.85
    Marker Score: 1758
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 3.85
    Marker Score: 4136.5
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 3.84
    Marker Score: 1723
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 3.84
    Marker Score: 1096
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 3.83
    Marker Score: 3605
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 3.82
    Marker Score: 1013
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 3.81
    Marker Score: 3280
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 3.81
    Marker Score: 3863
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 3.8
    Marker Score: 1252
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 3.8
    Marker Score: 3669
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 3.79
    Marker Score: 24197
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 3.79
    Marker Score: 3144
  • Cell Name: Schwann cell precursor (CL0002375)
    Fold Change: 3.78
    Marker Score: 941
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 3.78
    Marker Score: 879
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 3.77
    Marker Score: 4317
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 3.76
    Marker Score: 990
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 3.76
    Marker Score: 1371
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 3.75
    Marker Score: 2611
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 3.75
    Marker Score: 2837
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 3.74
    Marker Score: 3334
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 3.74
    Marker Score: 2475
  • Cell Name: lung neuroendocrine cell (CL1000223)
    Fold Change: 3.73
    Marker Score: 1053
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: 3.73
    Marker Score: 4125.5
  • Cell Name: S cone cell (CL0003050)
    Fold Change: 3.73
    Marker Score: 1121
  • Cell Name: tendon cell (CL0000388)
    Fold Change: 3.72
    Marker Score: 915

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Other Information

**Key characteristics:** * The gene is located on chromosome 15q21.1. * It is a large gene (11.2 kb) with 13 exons and 12 introns. * The protein encoded by RPS24 is a ribosomal protein. * It is expressed in high levels in epithelial cells of the exocrine pancreas, myoepithelial cells of the mammary gland, and thyroid follicular cells. * It is also expressed in low levels in malignant cells, professional antigen presenting cells, mature T cells, NKp46-positive innate lymphoid cells, and human radial glial cells. **Pathways and functions:** * The RPS24 gene is involved in a variety of cellular processes, including translation, cell growth, and differentiation. * It is essential for the initiation of translation, and its expression is upregulated in cells that are actively translating mRNA. * It is also involved in the termination of translation, and its expression is downregulated in cells that are not translating mRNA. * The protein encoded by RPS24 is a key regulator of protein synthesis, and its expression is often altered in disease. **Clinical significance:** * Mutations in the RPS24 gene have been linked to a number of human diseases, including cancer and diabetes. * These mutations can disrupt the normal function of the RPS24 protein, leading to the development of these diseases. * Research on the RPS24 gene is therefore an important area of investigation for the development of new treatments for cancer and other diseases.

Genular Protein ID: 2429359725

Symbol: RS24_HUMAN

Name: 40S ribosomal protein S24

UniProtKB Accession Codes:

P62847 E7EPK6 P16632 Q5T0P7 Q5T0P8 Q7Z3D1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 EMDB 67 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 91 PDBsum 84 PIR 2 PRIDE 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 18 RefSeq 4 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 3 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2210388

Title: A cDNA encoding human ribosomal protein S24.

PubMed ID: 2210388

DOI: 10.1016/0378-1119(90)90103-x

PubMed ID: 8647458

Title: The gene encoding human ribosomal protein S24 and tissue-specific expression of differentially spliced mRNAs.

PubMed ID: 8647458

DOI: 10.1016/0378-1119(96)88652-5

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706699

Title: Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.

PubMed ID: 8706699

DOI: 10.1111/j.1432-1033.1996.0144u.x

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 17186470

Title: Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia.

PubMed ID: 17186470

DOI: 10.1086/510020

PubMed ID: 18230666

Title: Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder.

PubMed ID: 18230666

DOI: 10.1093/hmg/ddn015

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24524803

Title: A new system for naming ribosomal proteins.

PubMed ID: 24524803

DOI: 10.1016/j.sbi.2014.01.002

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 23636399

Title: Structures of the human and Drosophila 80S ribosome.

PubMed ID: 23636399

DOI: 10.1038/nature12104

PubMed ID: 34516797

Title: Nucleolar maturation of the human small subunit processome.

PubMed ID: 34516797

DOI: 10.1126/science.abj5338

Sequence Information:

  • Length: 133
  • Mass: 15423
  • Checksum: CE9065C0764D60A6
  • Sequence:
    • MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT TPDVIFVFGF 
RTHFGGGKTT GFGMIYDSLD YAKKNEPKHR LARHGLYEKK KTSRKQRKER KNRMKKVRGT 
AKANVGAGKK PKE

Genular Protein ID: 4015371908

Symbol: A0A2R8Y849_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2R8Y849

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 3 GO 5 Gene3D 1 GeneTree 1 HAMAP 1 HGNC 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 1 Pfam 1 Proteomes 2 RefSeq 2 RuleBase 2 SAM 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 131
  • Mass: 15197
  • Checksum: 3190764D60A6DD57
  • Sequence:
    • MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT TPDVIFVFGF 
RTHFGGGKTT GFGMIYDSLD YAKKNEPKHR LARHGLYEKK KTSRKQRKER KNRMKKVRGT 
AKANVGAGKK K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.