Details for: SSBP1

Gene ID: 6742

Symbol: SSBP1

Ensembl ID: ENSG00000106028

Description: single stranded DNA binding protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 426.2426
    Cell Significance Index: -66.3000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 227.9184
    Cell Significance Index: -57.8100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 213.2067
    Cell Significance Index: -87.8300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 191.2427
    Cell Significance Index: -90.2900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 187.4429
    Cell Significance Index: -76.1500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 164.6820
    Cell Significance Index: -84.7100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 134.9732
    Cell Significance Index: -90.5700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 80.3619
    Cell Significance Index: -76.7300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 65.5011
    Cell Significance Index: -80.7600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 23.1255
    Cell Significance Index: -61.9500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 21.7559
    Cell Significance Index: -85.8500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 19.5770
    Cell Significance Index: -60.1300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.9797
    Cell Significance Index: -24.0300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 4.9507
    Cell Significance Index: 41.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.9534
    Cell Significance Index: 138.8100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.5264
    Cell Significance Index: 346.9500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.5050
    Cell Significance Index: 65.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.3040
    Cell Significance Index: 415.3400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 2.2943
    Cell Significance Index: 162.2600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.2362
    Cell Significance Index: 274.9600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.2193
    Cell Significance Index: 1212.0100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.0055
    Cell Significance Index: 69.6900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.9585
    Cell Significance Index: 53.3100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.9445
    Cell Significance Index: 859.7000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.8913
    Cell Significance Index: 122.0200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.7399
    Cell Significance Index: 81.1200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.6571
    Cell Significance Index: 15.2600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.6456
    Cell Significance Index: 17.8900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.6241
    Cell Significance Index: 34.0000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.6082
    Cell Significance Index: 83.5400
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.5805
    Cell Significance Index: 36.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.5315
    Cell Significance Index: 180.6100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.5030
    Cell Significance Index: 44.1400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.4709
    Cell Significance Index: 190.0300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.2482
    Cell Significance Index: 14.1800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.2002
    Cell Significance Index: 89.4500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.1273
    Cell Significance Index: 30.1000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9604
    Cell Significance Index: 123.1200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9352
    Cell Significance Index: 185.6000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9060
    Cell Significance Index: 181.7500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7635
    Cell Significance Index: 273.8700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4777
    Cell Significance Index: 10.3500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4170
    Cell Significance Index: 71.2000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3779
    Cell Significance Index: 61.4600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2299
    Cell Significance Index: 22.7400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.2282
    Cell Significance Index: 11.5300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2070
    Cell Significance Index: 143.2000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1844
    Cell Significance Index: 139.5900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1258
    Cell Significance Index: 113.6000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0724
    Cell Significance Index: 3.8000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0630
    Cell Significance Index: 118.5500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0595
    Cell Significance Index: 43.6300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0400
    Cell Significance Index: 0.6700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0370
    Cell Significance Index: 57.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0309
    Cell Significance Index: 57.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0037
    Cell Significance Index: -2.3700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0103
    Cell Significance Index: -7.6200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0130
    Cell Significance Index: -17.7400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0314
    Cell Significance Index: -1.7600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0462
    Cell Significance Index: -4.7200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0568
    Cell Significance Index: -35.4700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0595
    Cell Significance Index: -11.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0711
    Cell Significance Index: -4.4800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0901
    Cell Significance Index: -40.9000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0931
    Cell Significance Index: -2.6700
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.1052
    Cell Significance Index: -0.8400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1095
    Cell Significance Index: -61.7300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1260
    Cell Significance Index: -3.5200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1614
    Cell Significance Index: -34.0000
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.1827
    Cell Significance Index: -1.5700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2057
    Cell Significance Index: -10.7200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2873
    Cell Significance Index: -33.4800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2999
    Cell Significance Index: -86.3000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3037
    Cell Significance Index: -10.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3114
    Cell Significance Index: -45.2700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3190
    Cell Significance Index: -36.5500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3640
    Cell Significance Index: -9.3000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.5145
    Cell Significance Index: -9.5100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.5922
    Cell Significance Index: -10.4700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.5977
    Cell Significance Index: -45.8700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6258
    Cell Significance Index: -49.5700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.6647
    Cell Significance Index: -9.9600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.7223
    Cell Significance Index: -9.8600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.7234
    Cell Significance Index: -32.7900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7273
    Cell Significance Index: -32.1700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7446
    Cell Significance Index: -23.8500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.7524
    Cell Significance Index: -85.8900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7669
    Cell Significance Index: -79.8500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.8873
    Cell Significance Index: -33.6000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.9471
    Cell Significance Index: -65.5000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -1.0293
    Cell Significance Index: -42.1800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -1.1025
    Cell Significance Index: -14.1200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1543
    Cell Significance Index: -70.7700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.3924
    Cell Significance Index: -35.7900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.5223
    Cell Significance Index: -38.0500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.5399
    Cell Significance Index: -26.3900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.5533
    Cell Significance Index: -45.7500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.6996
    Cell Significance Index: -55.6500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.7364
    Cell Significance Index: -60.8300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.7538
    Cell Significance Index: -55.8600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SSBP1 is a single-stranded DNA-binding protein that exhibits high affinity for single-stranded DNA (ssDNA), thereby regulating DNA replication, transcription, and repair. Its unique ability to bind ssDNA makes it an essential component in the regulation of mitochondrial DNA (mtDNA) replication and transcription. Furthermore, SSBP1 has been shown to interact with various proteins, including helicases, which are critical for DNA unwinding and replication. **Pathways and Functions:** SSBP1 is involved in multiple cellular pathways, including: 1. **Chromatin binding and DNA unwinding**: SSBP1 regulates chromatin structure and facilitates DNA unwinding during replication and transcription. 2. **Mitochondrial biogenesis and replication**: SSBP1 plays a crucial role in promoting mtDNA replication and transcription, which is essential for the proper functioning of mitochondria. 3. **Extracellular exosome and protein metabolism**: SSBP1 is involved in the regulation of protein degradation and secretion through the exosome pathway. 4. **Single-stranded DNA binding**: SSBP1's high affinity for ssDNA enables it to regulate DNA replication and repair. **Clinical Significance:** SSBP1's involvement in various cellular processes makes it a potential target for therapeutic interventions. Some of the clinical implications of SSBP1 dysregulation include: 1. **Mitochondrial disorders**: Altered SSBP1 expression has been linked to mitochondrial diseases, such as mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). 2. **Cancer**: SSBP1's role in regulating mtDNA replication and transcription suggests its potential involvement in cancer development and progression. 3. **Neurological disorders**: SSBP1's interaction with helicases may contribute to the pathogenesis of neurological disorders, such as Alzheimer's disease and Parkinson's disease. **Significantly Expressed Cells:** SSBP1 is highly expressed in various cell types, including: 1. **Erythroid progenitor cells**: SSBP1 plays a crucial role in the regulation of mtDNA replication and transcription in these cells. 2. **Myeloid dendritic cells**: SSBP1 is involved in the regulation of protein degradation and secretion through the exosome pathway. 3. **CD14-low, CD16-positive monocytes**: SSBP1's expression in these cells suggests its potential involvement in immune responses. 4. **Embryonic stem cells**: SSBP1's role in regulating mtDNA replication and transcription makes it essential for embryonic development. In conclusion, SSBP1 is a multifaceted protein that plays a critical role in various cellular processes, including DNA replication, transcriptional regulation, and mitochondrial biogenesis. Its dysregulation has been implicated in various clinical contexts, making it a potential target for therapeutic interventions. Further research is needed to fully elucidate the mechanisms underlying SSBP1's functions and to explore its potential applications in human disease.

Genular Protein ID: 2266977016

Symbol: SSBP_HUMAN

Name: Single-stranded DNA-binding protein, mitochondrial

UniProtKB Accession Codes:

Q04837

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 11 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PIRSF 1 PRIDE 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 5 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8482537

Title: Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB).

PubMed ID: 8482537

DOI: 10.1016/0378-1119(93)90370-i

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19892738

Title: Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini.

PubMed ID: 19892738

DOI: 10.1073/pnas.0908958106

PubMed ID: 12975372

Title: TWINKLE has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein.

PubMed ID: 12975372

DOI: 10.1074/jbc.m306981200

PubMed ID: 15167897

Title: Reconstitution of a minimal mtDNA replisome in vitro.

PubMed ID: 15167897

DOI: 10.1038/sj.emboj.7600257

PubMed ID: 16428295

Title: PDIP38 associates with proteins constituting the mitochondrial DNA nucleoid.

PubMed ID: 16428295

DOI: 10.1093/jb/mvi169

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18063578

Title: The layered structure of human mitochondrial DNA nucleoids.

PubMed ID: 18063578

DOI: 10.1074/jbc.m708444200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21953457

Title: Reduced stimulation of recombinant DNA polymerase gamma and mitochondrial DNA (mtDNA) helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA replication in animal cells.

PubMed ID: 21953457

DOI: 10.1074/jbc.m111.289983

PubMed ID: 23290262

Title: Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB).

PubMed ID: 23290262

DOI: 10.1016/j.dnarep.2012.11.009

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26446790

Title: Mitochondrial Single-stranded DNA-binding Proteins Stimulate the Activity of DNA Polymerase gamma by Organization of the Template DNA.

PubMed ID: 26446790

DOI: 10.1074/jbc.m115.673707

PubMed ID: 25550423

Title: Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins.

PubMed ID: 25550423

DOI: 10.1093/nar/gku1321

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 9033597

Title: Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4-A resolution.

PubMed ID: 9033597

DOI: 10.1038/nsb0297-153

PubMed ID: 31298765

Title: SSBP1 mutations in dominant optic atrophy with variable retinal degeneration.

PubMed ID: 31298765

DOI: 10.1002/ana.25550

PubMed ID: 31550240

Title: SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder.

PubMed ID: 31550240

DOI: 10.1172/jci128514

PubMed ID: 31550237

Title: Dominant mutations in mtDNA maintenance gene SSBP1 cause optic atrophy and foveopathy.

PubMed ID: 31550237

DOI: 10.1172/jci128513

Sequence Information:

  • Length: 148
  • Mass: 17260
  • Checksum: 98EE9E396D5636C2
  • Sequence:
    • MFRRPVLQVL RQFVRHESET TTSLVLERSL NRVHLLGRVG QDPVLRQVEG KNPVTIFSLA 
TNEMWRSGDS EVYQLGDVSQ KTTWHRISVF RPGLRDVAYQ YVKKGSRIYL EGKIDYGEYM 
DKNNVRRQAT TIIADNIIFL SDQTKEKE

Genular Protein ID: 2319929383

Symbol: B7Z268_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z268 B7WNJ6

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 3 Gene3D 1 HAMAP 1 InterPro 3 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 1 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 4 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 159
  • Mass: 18558
  • Checksum: 50E062C1840DA638
  • Sequence:
    • MFRRPVLQVL RQFVRHESET TTSLVLERSL NRVHLLGRVG QDPVLRQVEG KNPVTIFSLA 
TNEMWRSGDS EVYQLGDVSQ KTTWHRISVF RPGLRDVAYQ YVKKGSRIYL EGKIDYGEYM 
DKNNVRRQAT TIIAGKKLVK IAVFFFFSFS FLKAWLHCN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.