Details for: SUPT4H1

Gene ID: 6827

Symbol: SUPT4H1

Ensembl ID: ENSG00000213246

Description: SPT4 homolog, DSIF elongation factor subunit

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 152.0458
    Cell Significance Index: -23.6500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 97.9251
    Cell Significance Index: -40.3400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 85.5532
    Cell Significance Index: -21.7000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 83.8341
    Cell Significance Index: -39.5800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 78.3654
    Cell Significance Index: -40.3100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 58.8654
    Cell Significance Index: -39.5000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.1056
    Cell Significance Index: -33.4200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.2390
    Cell Significance Index: -34.5200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.9872
    Cell Significance Index: -39.4100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.8097
    Cell Significance Index: -23.6000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 4.1807
    Cell Significance Index: 33.3800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 4.0686
    Cell Significance Index: 86.6500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 4.0003
    Cell Significance Index: 276.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 3.3287
    Cell Significance Index: 387.9200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.8173
    Cell Significance Index: 458.2100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.7788
    Cell Significance Index: 51.3600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.4434
    Cell Significance Index: 64.2500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.2029
    Cell Significance Index: 132.2500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.0590
    Cell Significance Index: 71.5500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.0581
    Cell Significance Index: 132.7800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 2.0158
    Cell Significance Index: 219.2600
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.8018
    Cell Significance Index: 23.0800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.6912
    Cell Significance Index: 49.6700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.5489
    Cell Significance Index: 182.6600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.4636
    Cell Significance Index: 30.6400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.4212
    Cell Significance Index: 195.1700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.3016
    Cell Significance Index: 14.1500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.0794
    Cell Significance Index: 50.7300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9726
    Cell Significance Index: 531.1600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.9658
    Cell Significance Index: 71.9800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9513
    Cell Significance Index: 116.9700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.8943
    Cell Significance Index: 10.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8929
    Cell Significance Index: 114.4700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.8528
    Cell Significance Index: 377.0400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8468
    Cell Significance Index: 152.6500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.8000
    Cell Significance Index: 103.3600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7353
    Cell Significance Index: 72.7400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6292
    Cell Significance Index: 124.8700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.6038
    Cell Significance Index: 42.7000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5186
    Cell Significance Index: 13.9000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4883
    Cell Significance Index: 25.6400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.2897
    Cell Significance Index: 5.1200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2843
    Cell Significance Index: 7.5900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1170
    Cell Significance Index: 22.2700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0746
    Cell Significance Index: 14.9600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0733
    Cell Significance Index: 66.1700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0498
    Cell Significance Index: 1.1500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0276
    Cell Significance Index: 20.9200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0217
    Cell Significance Index: 0.4700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0038
    Cell Significance Index: 2.7900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0007
    Cell Significance Index: -0.1200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0019
    Cell Significance Index: -0.1900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0036
    Cell Significance Index: -0.0600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0056
    Cell Significance Index: -0.1600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0067
    Cell Significance Index: -4.9500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0081
    Cell Significance Index: -5.0700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0176
    Cell Significance Index: -0.6200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0206
    Cell Significance Index: -38.8500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0322
    Cell Significance Index: -3.6800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0327
    Cell Significance Index: -1.4800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0327
    Cell Significance Index: -11.7200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0502
    Cell Significance Index: -28.3200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0514
    Cell Significance Index: -35.5800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0532
    Cell Significance Index: -0.4900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0541
    Cell Significance Index: -11.4000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0623
    Cell Significance Index: -39.5700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0754
    Cell Significance Index: -2.1600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0915
    Cell Significance Index: -41.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1048
    Cell Significance Index: -30.1400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1143
    Cell Significance Index: -2.9200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1239
    Cell Significance Index: -3.3200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1480
    Cell Significance Index: -16.9600
  • Cell Name: theca cell (CL0000503)
    Fold Change: -0.1906
    Cell Significance Index: -1.1200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2214
    Cell Significance Index: -7.0900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2709
    Cell Significance Index: -7.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2720
    Cell Significance Index: -39.5400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3477
    Cell Significance Index: -27.5400
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.3611
    Cell Significance Index: -5.0700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3798
    Cell Significance Index: -39.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3826
    Cell Significance Index: -21.4700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4518
    Cell Significance Index: -27.7700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.4521
    Cell Significance Index: -2.7800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4971
    Cell Significance Index: -38.1500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.5081
    Cell Significance Index: -5.2600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5729
    Cell Significance Index: -14.7300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5825
    Cell Significance Index: -36.7100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6016
    Cell Significance Index: -40.4500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.6308
    Cell Significance Index: -9.7600
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: -0.6438
    Cell Significance Index: -4.0300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6444
    Cell Significance Index: -39.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.6884
    Cell Significance Index: -32.1000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6970
    Cell Significance Index: -20.5300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.7283
    Cell Significance Index: -36.8100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.7319
    Cell Significance Index: -38.0200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.7867
    Cell Significance Index: -28.8800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.8286
    Cell Significance Index: -36.6500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.8597
    Cell Significance Index: -23.4000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.8706
    Cell Significance Index: -5.2600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.9001
    Cell Significance Index: -10.7300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.9383
    Cell Significance Index: -16.0800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Homolog of SPT4:** SPT4H1 shares structural and functional similarities with the SPT4 protein, a key component of the negative elongation factor complex (NELC) in mammals. 2. **RNA Polymerase II Regulation:** SPT4H1 is involved in the negative regulation of transcription elongation by RNA polymerase II, a process critical for the control of gene expression. 3. **HIV Transcription Elongation:** SPT4H1 plays a crucial role in the modulation of HIV transcription elongation, particularly in the absence of the Tat protein, which is essential for viral transcription. 4. **Cell Type-Specific Expression:** SPT4H1 is highly expressed in various cell types, including immune cells, such as CD14-positive and CD16-positive monocytes. **Pathways and Functions:** 1. **HIV Transcription Elongation:** SPT4H1 acts as a negative regulator of HIV transcription elongation, thereby influencing the progression of the disease. 2. **RNA Polymerase II Regulation:** SPT4H1 is involved in the negative regulation of transcription elongation by RNA polymerase II, a process critical for the control of gene expression. 3. **Gene Expression (Transcription):** SPT4H1 is involved in the regulation of gene expression through its role in transcription elongation. 4. **Disease Pathways:** SPT4H1 is implicated in various disease pathways, including infectious diseases, such as HIV infection, and cancer, where it regulates transcription elongation and cell growth. **Clinical Significance:** 1. **HIV Infection:** SPT4H1 plays a critical role in the regulation of HIV transcription elongation, and its dysregulation may contribute to the progression of the disease. 2. **Immune Regulation:** SPT4H1 is involved in the regulation of immune responses, particularly in the context of HIV infection, where it modulates the expression of genes involved in immune cell activation and function. 3. **Cancer:** SPT4H1 may also play a role in cancer development and progression, where it regulates transcription elongation and cell growth. 4. **Therapeutic Targets:** Understanding the role of SPT4H1 in HIV transcription elongation and immune regulation may lead to the identification of new therapeutic targets for the treatment of HIV infection and other diseases. In conclusion, SPT4H1 is a crucial gene involved in the regulation of HIV transcription elongation and immune regulation. Its dysregulation may contribute to the progression of HIV infection and other diseases. Further research is needed to fully understand the role of SPT4H1 in these contexts and to identify potential therapeutic targets for the treatment of these diseases.

Genular Protein ID: 3419575640

Symbol: SPT4H_HUMAN

Name: Transcription elongation factor SPT4

UniProtKB Accession Codes:

P63272 B2R4X8 D3DTZ4 Q16550 Q62387 Q6ZP89

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 4 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EMDB 20 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 15 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 15 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8786137

Title: Isolation and characterization of the human and mouse homologues (SUPT4H and Supt4h) of the yeast SPT4 gene.

PubMed ID: 8786137

DOI: 10.1006/geno.1996.0299

PubMed ID: 8649394

Title: Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae.

PubMed ID: 8649394

DOI: 10.1128/mcb.16.6.2848

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9857195

Title: Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro.

PubMed ID: 9857195

DOI: 10.1093/emboj/17.24.7395

PubMed ID: 9450929

Title: DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.

PubMed ID: 9450929

DOI: 10.1101/gad.12.3.343

PubMed ID: 10199401

Title: NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation.

PubMed ID: 10199401

DOI: 10.1016/s0092-8674(00)80713-8

PubMed ID: 10075709

Title: Structure and function of the human transcription elongation factor DSIF.

PubMed ID: 10075709

DOI: 10.1074/jbc.274.12.8085

PubMed ID: 10454543

Title: Tat-SF1 protein associates with RAP30 and human SPT5 proteins.

PubMed ID: 10454543

DOI: 10.1128/mcb.19.9.5960

PubMed ID: 10912001

Title: FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH.

PubMed ID: 10912001

DOI: 10.1016/s1097-2765(00)80272-5

PubMed ID: 10757782

Title: Domains in the SPT5 protein that modulate its transcriptional regulatory properties.

PubMed ID: 10757782

DOI: 10.1128/mcb.20.9.2970-2983.2000

PubMed ID: 11112772

Title: DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation.

PubMed ID: 11112772

DOI: 10.1074/jbc.m006130200

PubMed ID: 11553615

Title: A highly purified RNA polymerase II elongation control system.

PubMed ID: 11553615

DOI: 10.1074/jbc.m104967200

PubMed ID: 12653964

Title: Structure-function analysis of human Spt4: evidence that hSpt4 and hSpt5 exert their roles in transcriptional elongation as parts of the DSIF complex.

PubMed ID: 12653964

DOI: 10.1046/j.1365-2443.2003.00638.x

PubMed ID: 12718890

Title: Methylation of SPT5 regulates its interaction with RNA polymerase II and transcriptional elongation properties.

PubMed ID: 12718890

DOI: 10.1016/s1097-2765(03)00101-1

PubMed ID: 15380072

Title: Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila.

PubMed ID: 15380072

DOI: 10.1016/j.cub.2004.08.066

PubMed ID: 15060154

Title: Human Spt6 stimulates transcription elongation by RNA polymerase II in vitro.

PubMed ID: 15060154

DOI: 10.1128/mcb.24.8.3324-3336.2004

PubMed ID: 15136722

Title: Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II.

PubMed ID: 15136722

DOI: 10.1073/pnas.0401493101

PubMed ID: 16214896

Title: A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS.

PubMed ID: 16214896

DOI: 10.1073/pnas.0409405102

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 37478862

Title: Orphan quality control shapes network dynamics and gene expression.

PubMed ID: 37478862

DOI: 10.1016/j.cell.2023.06.015

PubMed ID: 19860741

Title: Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface.

PubMed ID: 19860741

DOI: 10.1042/bj20091422

PubMed ID: 28892040

Title: Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp.

PubMed ID: 28892040

DOI: 10.1038/nsmb.3465

Sequence Information:

  • Length: 117
  • Mass: 13193
  • Checksum: 09EDF007501D0F03
  • Sequence:
    • MALETVPKDL RHLRACLLCS LVKTIDQFEY DGCDNCDAYL QMKGNREMVY DCTSSSFDGI 
IAMMSPEDSW VSKWQRVSNF KPGVYAVSVT GRLPQGIVRE LKSRGVAYKS RDTAIKT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.