Details for: TPI1

Gene ID: 7167

Symbol: TPI1

Ensembl ID: ENSG00000111669

Description: triosephosphate isomerase 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 6.55
    Marker Score: 4382
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 5.01
    Marker Score: 3535.5
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 4.54
    Marker Score: 5478
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 4.5
    Marker Score: 2733
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 4.39
    Marker Score: 1285.5
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 4.22
    Marker Score: 17511
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 4.14
    Marker Score: 3907
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 3.95
    Marker Score: 1457.5
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 3.85
    Marker Score: 3271
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 3.76
    Marker Score: 10399.5
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 3.71
    Marker Score: 48922
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 3.7
    Marker Score: 3300
  • Cell Name: blood cell (CL0000081)
    Fold Change: 3.64
    Marker Score: 42339.5
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 3.64
    Marker Score: 27101
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 3.62
    Marker Score: 1158.5
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 3.62
    Marker Score: 202283
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 3.6
    Marker Score: 35623
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.53
    Marker Score: 8610
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 3.51
    Marker Score: 5401.5
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 3.47
    Marker Score: 9305
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 3.41
    Marker Score: 4735
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 3.41
    Marker Score: 3556
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 3.36
    Marker Score: 6827
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 3.33
    Marker Score: 44683
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 3.32
    Marker Score: 9680
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 3.32
    Marker Score: 2503
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.31
    Marker Score: 21516.5
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 3.31
    Marker Score: 25823.5
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 3.29
    Marker Score: 11667.5
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 3.28
    Marker Score: 10284
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 3.27
    Marker Score: 113286
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 3.16
    Marker Score: 7974
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 3.15
    Marker Score: 1036
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 3.11
    Marker Score: 18428.5
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 3.1
    Marker Score: 2062.5
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 3.08
    Marker Score: 4365
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 3.06
    Marker Score: 8744
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 3.05
    Marker Score: 1740
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 3.04
    Marker Score: 3380
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 3.04
    Marker Score: 19811
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 3.04
    Marker Score: 14585
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 3.04
    Marker Score: 5918
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 3.03
    Marker Score: 2384
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 2.99
    Marker Score: 1666
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 2.98
    Marker Score: 4947
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 2.98
    Marker Score: 25709.5
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.98
    Marker Score: 9398
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 2.96
    Marker Score: 1680
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 2.95
    Marker Score: 4843.5
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 2.95
    Marker Score: 2513.5
  • Cell Name: ventricular cardiac muscle cell (CL2000046)
    Fold Change: 2.92
    Marker Score: 1213.5
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 2.92
    Marker Score: 2826
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 2.91
    Marker Score: 3332
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.91
    Marker Score: 98989
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 2.89
    Marker Score: 1899
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 2.88
    Marker Score: 926
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 2.87
    Marker Score: 5398
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 2.87
    Marker Score: 3944
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.86
    Marker Score: 11028
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 2.86
    Marker Score: 4543.5
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 2.86
    Marker Score: 1520
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 2.85
    Marker Score: 1573
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.83
    Marker Score: 2218.5
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.83
    Marker Score: 1775
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 2.82
    Marker Score: 1475
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.81
    Marker Score: 17965.5
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 2.8
    Marker Score: 7125
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.8
    Marker Score: 4047
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.78
    Marker Score: 27982
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.77
    Marker Score: 662.5
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 2.77
    Marker Score: 14557
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: 2.77
    Marker Score: 1246.5
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 2.77
    Marker Score: 2468
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 2.76
    Marker Score: 1128
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.75
    Marker Score: 11805.5
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 2.75
    Marker Score: 1675
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 2.74
    Marker Score: 929
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 2.74
    Marker Score: 1184.5
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 2.74
    Marker Score: 1141
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 2.74
    Marker Score: 2777
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.74
    Marker Score: 5717
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 2.73
    Marker Score: 4387
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.73
    Marker Score: 11759.5
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.73
    Marker Score: 7418
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 2.72
    Marker Score: 2826
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 2.7
    Marker Score: 2705
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 2.7
    Marker Score: 2112
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 2.69
    Marker Score: 3962
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 2.68
    Marker Score: 928
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 2.68
    Marker Score: 6937
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.67
    Marker Score: 7936
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.67
    Marker Score: 2834
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.66
    Marker Score: 2842.5
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.66
    Marker Score: 1937
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 2.66
    Marker Score: 2176.5
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 2.66
    Marker Score: 1368
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.66
    Marker Score: 29915
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 2.66
    Marker Score: 6952
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 2.64
    Marker Score: 1494
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 2.64
    Marker Score: 1408

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Other Information

**Key Characteristics** TPI1 exhibits several key characteristics that underscore its significance in cellular metabolism: 1. **Enzymatic activity**: TPI1 is a triosephosphate isomerase, catalyzing the isomerization of DHAP to G3P, a reaction that is essential for the progression of glycolysis. 2. **Subcellular localization**: TPI1 is primarily associated with the cytosol, where it can access its substrates and interact with other glycolytic enzymes. 3. **Expression patterns**: TPI1 is expressed in a wide range of cell types, including immune cells, neurons, and muscle cells, suggesting its involvement in various physiological processes. 4. **Regulation**: TPI1 is subject to various regulatory mechanisms, including post-translational modifications and transcriptional control, which allow for fine-tuned expression in response to changing cellular needs. **Pathways and Functions** TPI1 plays a critical role in several metabolic pathways, including: 1. **Glycolysis**: TPI1 catalyzes the conversion of DHAP to G3P, enabling the efficient breakdown of glucose for energy production. 2. **Gluconeogenesis**: TPI1 participates in the gluconeogenic pathway, generating G3P from non-carbohydrate sources, such as lactate and glycerol. 3. **Glyceraldehyde-3-phosphate biosynthetic process**: TPI1 is involved in the generation of G3P from glyceraldehyde, a precursor molecule for glycolysis. 4. **Methylglyoxal biosynthetic process**: TPI1 catalyzes the formation of methylglyoxal, a key intermediate in the glyoxalase pathway. **Clinical Significance** Dysregulation of TPI1 expression or activity has been implicated in various diseases and conditions, including: 1. **Diabetes**: Altered TPI1 expression has been observed in diabetic patients, suggesting a potential role in glucose metabolism and insulin resistance. 2. **Cancer**: TPI1 has been identified as a prognostic marker for various types of cancer, including colorectal and breast cancer. 3. **Neurological disorders**: TPI1 expression has been linked to neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. 4. **Immune system dysregulation**: TPI1 has been implicated in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and lupus. In conclusion, TPI1 is a critical enzyme involved in various metabolic pathways, with significant implications for cellular homeostasis and function. Further research into the regulation and clinical significance of TPI1 will provide valuable insights into the molecular mechanisms underlying various diseases and conditions.

Genular Protein ID: 3910351010

Symbol: TPIS_HUMAN

Name: Triose-phosphate isomerase

UniProtKB Accession Codes:

P60174 B7Z5D8 D3DUS9 P00938 Q6FHP9 Q6IS07 Q8WWD0 Q96AG5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CPTAC 1 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DOSAC-COBS-2DPAGE 1 DisGeNET 1 DrugBank 17 EC 2 EMBL 17 EPD 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 MoonProt 1 NCBI Taxonomy 1 NCBIfam 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 30 PDBsum 27 PIR 1 PRIDE 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 2 RefSeq 3 Rhea 2 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SWISS-2DPAGE 1 SignaLink 1 SwissPalm 1 TopDownProteomics 3 TreeFam 1 UCD-2DPAGE 1 UCSC 1 UniPathway 2 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2579079

Title: Human triosephosphate isomerase cDNA and protein structure. Studies of triosephosphate isomerase deficiency in man.

PubMed ID: 2579079

DOI: 10.1016/s0021-9258(19)83687-6

PubMed ID: 4022011

Title: Characterization of the functional gene and several processed pseudogenes in the human triosephosphate isomerase gene family.

PubMed ID: 4022011

DOI: 10.1128/mcb.5.7.1694-1706.1985

PubMed ID: 8723724

Title: A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.

PubMed ID: 8723724

DOI: 10.1101/gr.6.4.314

PubMed ID: 9074930

Title: Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination.

PubMed ID: 9074930

DOI: 10.1101/gr.7.3.268

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 2925688

Title: Transcriptional regulatory sequences of the housekeeping gene for human triosephosphate isomerase.

PubMed ID: 2925688

DOI: 10.1016/s0021-9258(18)83716-4

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6434534

Title: Primary structure of human triosephosphate isomerase.

PubMed ID: 6434534

DOI: 10.1016/s0021-9258(20)71304-9

PubMed ID: 9150946

Title: Two-dimensional electrophoretic analysis of human breast carcinoma proteins: mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2.

PubMed ID: 9150946

DOI: 10.1002/elps.1150180342

PubMed ID: 9150948

Title: A two-dimensional gel database of human colon carcinoma proteins.

PubMed ID: 9150948

DOI: 10.1002/elps.1150180344

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16807684

Title: Phosphoproteomic analysis of the human pituitary.

PubMed ID: 16807684

DOI: 10.1007/s11102-006-8916-x

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 17693683

Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.

PubMed ID: 17693683

DOI: 10.1074/mcp.m700120-mcp200

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 8061610

Title: Crystal structure of recombinant human triosephosphate isomerase at 2.8-A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme.

PubMed ID: 8061610

DOI: 10.1002/pro.5560030510

PubMed ID: 16511037

Title: Structure of a high-resolution crystal form of human triosephosphate isomerase: improvement of crystals using the gel-tube method.

PubMed ID: 16511037

DOI: 10.1107/s1744309105008341

PubMed ID: 18562316

Title: Structural basis of human triosephosphate isomerase deficiency: mutation E104D is related to alterations of a conserved water network at the dimer interface.

PubMed ID: 18562316

DOI: 10.1074/jbc.m802145200

PubMed ID: 2876430

Title: Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme.

PubMed ID: 2876430

DOI: 10.1073/pnas.83.20.7903

PubMed ID: 1339398

Title: Human triosephosphate isomerase: substitution of Arg for Gly at position 122 in a thermolabile electromorph variant, TPI-Manchester.

PubMed ID: 1339398

DOI: 10.1007/bf02265287

PubMed ID: 8503454

Title: Human triosephosphate isomerase deficiency resulting from mutation of Phe-240.

PubMed ID: 8503454

PubMed ID: 8571957

Title: Molecular analysis of a series of alleles in humans with reduced activity at the triosephosphate isomerase locus.

PubMed ID: 8571957

PubMed ID: 9338582

Title: Evidence for founder effect of the Glu104Asp substitution and identification of new mutations in triosephosphate isomerase deficiency.

PubMed ID: 9338582

DOI: 10.1002/(sici)1098-1004(1997)10:4<290::aid-humu4>3.0.co;2-l

Sequence Information:

  • Length: 249
  • Mass: 26669
  • Checksum: 73844175635F858E
  • Sequence:
    • MAPSRKFFVG GNWKMNGRKQ SLGELIGTLN AAKVPADTEV VCAPPTAYID FARQKLDPKI 
AVAAQNCYKV TNGAFTGEIS PGMIKDCGAT WVVLGHSERR HVFGESDELI GQKVAHALAE 
GLGVIACIGE KLDEREAGIT EKVVFEQTKV IADNVKDWSK VVLAYEPVWA IGTGKTATPQ 
QAQEVHEKLR GWLKSNVSDA VAQSTRIIYG GSVTGATCKE LASQPDVDGF LVGGASLKPE 
FVDIINAKQ

Genular Protein ID: 1117654037

Symbol: Q53HE2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53HE2

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 5 DNASU 1 EC 2 EMBL 2 GO 4 Gene3D 1 Genevisible 1 GenomeRNAi 1 HAMAP 1 IntAct 1 InterPro 5 KEGG 1 MINT 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 PharmGKB 1 RefSeq 1 Rhea 2 RuleBase 1 SMR 1 SUPFAM 1 UniPathway 2 iPTMnet 1

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 249
  • Mass: 26713
  • Checksum: 73965259B19F4470
  • Sequence:
    • MAPSRKFFVG GNWKMNGRKQ SLGELIGTLN AAKVPADTEV VCAPPTAYID FARQKLDPKI 
AVAAQNCYKV TNGAFTGEIS PGMIKDCGAT WVVRGHSERR HVFGESDELI GQKVAHALAE 
GLGVIACIGE KLDEREAGIT EKVVFEQTKV IADNVKDWSK VVLAYEPVWA IGTGKTATPQ 
QAQEVHEKLR GWLKSNVSDA VAQSTRIIYG GSVTGATCKE LASQPDVDGF LVGGASLKPE 
FVDIINAKQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.