Details for: TPP2

Gene ID: 7174

Symbol: TPP2

Ensembl ID: ENSG00000134900

Description: tripeptidyl peptidase 2

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 2.69
    Marker Score: 11209
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.97
    Marker Score: 74684
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.84
    Marker Score: 14088
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.82
    Marker Score: 7597
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.74
    Marker Score: 64092
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.68
    Marker Score: 6512
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.65
    Marker Score: 24723
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.64
    Marker Score: 3610.5
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.59
    Marker Score: 31680
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.59
    Marker Score: 15114
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.58
    Marker Score: 13589
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.58
    Marker Score: 97254
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.57
    Marker Score: 6492
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.51
    Marker Score: 14190
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.47
    Marker Score: 1696
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.47
    Marker Score: 5968
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.42
    Marker Score: 1569
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.35
    Marker Score: 2082
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.33
    Marker Score: 28321
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.28
    Marker Score: 12961
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.28
    Marker Score: 1697
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.27
    Marker Score: 402
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.27
    Marker Score: 549
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.24
    Marker Score: 655
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.24
    Marker Score: 691
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.24
    Marker Score: 614.5
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.23
    Marker Score: 714
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.22
    Marker Score: 12549
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.19
    Marker Score: 13793
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.18
    Marker Score: 344
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.16
    Marker Score: 61585
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.16
    Marker Score: 652
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.15
    Marker Score: 3117
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.14
    Marker Score: 2732
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.14
    Marker Score: 830
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.14
    Marker Score: 1144
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.13
    Marker Score: 1209
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.13
    Marker Score: 5215
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.12
    Marker Score: 1391
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.12
    Marker Score: 1359
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.11
    Marker Score: 2145
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.11
    Marker Score: 1590
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.11
    Marker Score: 463
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.1
    Marker Score: 1478
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.09
    Marker Score: 1176
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.07
    Marker Score: 434
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.06
    Marker Score: 16548
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.06
    Marker Score: 631
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 1.04
    Marker Score: 360
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.04
    Marker Score: 388
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.04
    Marker Score: 658
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.03
    Marker Score: 1241
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.03
    Marker Score: 889
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.01
    Marker Score: 1399
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.01
    Marker Score: 925
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.01
    Marker Score: 349
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1
    Marker Score: 1260
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1
    Marker Score: 6447
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71612
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.99
    Marker Score: 47837
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: 0.99
    Marker Score: 261
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.99
    Marker Score: 400
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 0.99
    Marker Score: 1944
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.99
    Marker Score: 4272
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 0.99
    Marker Score: 1765
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.98
    Marker Score: 311
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30374
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.98
    Marker Score: 586
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.97
    Marker Score: 645
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 0.97
    Marker Score: 267
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.96
    Marker Score: 2031.5
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.96
    Marker Score: 657
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 0.96
    Marker Score: 753
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 0.96
    Marker Score: 653
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.96
    Marker Score: 1016
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.96
    Marker Score: 465
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 0.95
    Marker Score: 690
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.95
    Marker Score: 1002
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.95
    Marker Score: 227
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 0.94
    Marker Score: 1134
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.94
    Marker Score: 15122
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2386
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.94
    Marker Score: 876
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.93
    Marker Score: 456
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.93
    Marker Score: 1163
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.92
    Marker Score: 341.5
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 476
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 0.92
    Marker Score: 890
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.92
    Marker Score: 574.5
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.92
    Marker Score: 709
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 0.92
    Marker Score: 295
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 433
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 0.91
    Marker Score: 250
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.91
    Marker Score: 200
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.91
    Marker Score: 372
  • Cell Name: cardiac mesenchymal cell (CL0000569)
    Fold Change: 0.91
    Marker Score: 224
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 0.91
    Marker Score: 2545
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.9
    Marker Score: 260
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.9
    Marker Score: 901
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2683

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Other Information

**Key Characteristics:** 1. **Enzymatic Activity:** TPP2 is a serine-type endopeptidase that hydrolyzes tripeptides, which are essential for the processing and presentation of antigens to the immune system. 2. **Expression Pattern:** TPP2 is widely expressed in various cell types, including GABAergic neurons, immune cells, and epithelial cells. 3. **Pathway Involvement:** TPP2 is involved in several key pathways, including adaptive immune system, antigen processing, and ubiquitination of proteins. 4. **Protein Binding:** TPP2 interacts with various proteins, including ubiquitin, which is essential for protein degradation and homeostasis. **Pathways and Functions:** 1. **Adaptive Immune System:** TPP2 plays a crucial role in the adaptive immune system by processing and presenting antigens to T-cells through MHC class I molecules. 2. **Antigen Processing:** TPP2 is involved in the ubiquitination and proteasomal degradation of antigens, which is essential for the presentation of antigens to T-cells. 3. **Intracellular Amino Acid Homeostasis:** TPP2 regulates intracellular amino acid levels by hydrolyzing tripeptides, which are essential for protein synthesis and degradation. 4. **Protein Polyubiquitination:** TPP2 interacts with ubiquitin, which is essential for protein degradation and homeostasis. **Clinical Significance:** 1. **Autoimmune Disorders:** Dysregulation of TPP2 has been implicated in several autoimmune disorders, including rheumatoid arthritis and multiple sclerosis. 2. **Neurological Conditions:** TPP2 has been linked to neurological conditions, including epilepsy and schizophrenia, due to its role in GABAergic neurotransmission. 3. **Cancer:** TPP2 has been found to be overexpressed in certain types of cancer, including lung and breast cancer, suggesting its potential role in tumorigenesis. 4. **Therapeutic Targeting:** TPP2 has been identified as a potential therapeutic target for the treatment of autoimmune disorders and neurological conditions. In conclusion, TPP2 is a crucial regulator of the immune response and cellular homeostasis. Its dysregulation has been implicated in several diseases, and its therapeutic targeting has shown promise in treating autoimmune disorders and neurological conditions. Further research is necessary to fully understand the mechanisms of TPP2 and its role in human disease.

Genular Protein ID: 2594628091

Symbol: TPP2_HUMAN

Name: Tripeptidyl-peptidase 2

UniProtKB Accession Codes:

P29144 Q5VZU8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 5 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 12 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SAM 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1840501

Title: Nucleotide sequence of cDNA covering the N-terminus of human tripeptidyl peptidase II.

PubMed ID: 1840501

PubMed ID: 1670990

Title: Characterization of cDNA for human tripeptidyl peptidase II: the N-terminal part of the enzyme is similar to subtilisin.

PubMed ID: 1670990

DOI: 10.1021/bi00215a025

PubMed ID: 1691635

Title: Immunological cross-reactivity between human tripeptidyl peptidase II and fibronectin.

PubMed ID: 1691635

DOI: 10.1042/bj2670149

PubMed ID: 3313395

Title: Active site of tripeptidyl peptidase II from human erythrocytes is of the subtilisin type.

PubMed ID: 3313395

DOI: 10.1073/pnas.84.21.7508

PubMed ID: 19747897

Title: A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.

PubMed ID: 19747897

DOI: 10.1016/j.bbrc.2009.09.021

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25525876

Title: Dual proteolytic pathways govern glycolysis and immune competence.

PubMed ID: 25525876

DOI: 10.1016/j.cell.2014.12.001

PubMed ID: 30533531

Title: TPP2 mutation associated with sterile brain inflammation mimicking MS.

PubMed ID: 30533531

DOI: 10.1212/nxg.0000000000000285

Sequence Information:

  • Length: 1249
  • Mass: 138350
  • Checksum: A26A6249DBF7F3DD
  • Sequence:
    • MATAATEEPF PFHGLLPKKE TGAASFLCRY PEYDGRGVLI AVLDTGVDPG APGMQVTTDG 
KPKIVDIIDT TGSGDVNTAT EVEPKDGEIV GLSGRVLKIP ASWTNPSGKY HIGIKNGYDF 
YPKALKERIQ KERKEKIWDP VHRVALAEAC RKQEEFDVAN NGSSQANKLI KEELQSQVEL 
LNSFEKKYSD PGPVYDCLVW HDGEVWRACI DSNEDGDLSK STVLRNYKEA QEYGSFGTAE 
MLNYSVNIYD DGNLLSIVTS GGAHGTHVAS IAAGHFPEEP ERNGVAPGAQ ILSIKIGDTR 
LSTMETGTGL IRAMIEVINH KCDLVNYSYG EATHWPNSGR ICEVINEAVW KHNIIYVSSA 
GNNGPCLSTV GCPGGTTSSV IGVGAYVSPD MMVAEYSLRE KLPANQYTWS SRGPSADGAL 
GVSISAPGGA IASVPNWTLR GTQLMNGTSM SSPNACGGIA LILSGLKANN IDYTVHSVRR 
ALENTAVKAD NIEVFAQGHG IIQVDKAYDY LVQNTSFANK LGFTVTVGNN RGIYLRDPVQ 
VAAPSDHGVG IEPVFPENTE NSEKISLQLH LALTSNSSWV QCPSHLELMN QCRHINIRVD 
PRGLREGLHY TEVCGYDIAS PNAGPLFRVP ITAVIAAKVN ESSHYDLAFT DVHFKPGQIR 
RHFIEVPEGA TWAEVTVCSC SSEVSAKFVL HAVQLVKQRA YRSHEFYKFC SLPEKGTLTE 
AFPVLGGKAI EFCIARWWAS LSDVNIDYTI SFHGIVCTAP QLNIHASEGI NRFDVQSSLK 
YEDLAPCITL KNWVQTLRPV SAKTKPLGSR DVLPNNRQLY EMVLTYNFHQ PKSGEVTPSC 
PLLCELLYES EFDSQLWIIF DQNKRQMGSG DAYPHQYSLK LEKGDYTIRL QIRHEQISDL 
ERLKDLPFIV SHRLSNTLSL DIHENHSFAL LGKKKSSNLT LPPKYNQPFF VTSLPDDKIP 
KGAGPGCYLA GSLTLSKTEL GKKADVIPVH YYLIPPPTKT KNGSKDKEKD SEKEKDLKEE 
FTEALRDLKI QWMTKLDSSD IYNELKETYP NYLPLYVARL HQLDAEKERM KRLNEIVDAA 
NAVISHIDQT ALAVYIAMKT DPRPDAATIK NDMDKQKSTL VDALCRKGCA LADHLLHTQA 
QDGAISTDAE GKEEEGESPL DSLAETFWET TKWTDLFDNK VLTFAYKHAL VNKMYGRGLK 
FATKLVEEKP TKENWKNCIQ LMKLLGWTHC ASFTENWLPI MYPPDYCVF

Genular Protein ID: 1883449860

Symbol: Q5VZU9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5VZU9

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EC 1 EMBL 1 EPD 2 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 4 GeneTree 1 GenomeRNAi 1 HGNC 1 IntAct 1 InterPro 12 MANE-Select 1 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 Pfam 10 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1262
  • Mass: 139766
  • Checksum: FD7528A15433F987
  • Sequence:
    • MATAATEEPF PFHGLLPKKE TGAASFLCRY PEYDGRGVLI AVLDTGVDPG APGMQVTTDG 
KPKIVDIIDT TGSGDVNTAT EVEPKDGEIV GLSGRVLKIP ASWTNPSGKY HIGIKNGYDF 
YPKALKERIQ KERKEKIWDP VHRVALAEAC RKQEEFDVAN NGSSQANKLI KEELQSQVEL 
LNSFEKKYSD PGPVYDCLVW HDGEVWRACI DSNEDGDLSK STVLRNYKEA QEYGSFGTAE 
MLNYSVNIYD DGNLLSIVTS GGAHGTHVAS IAAGHFPEEP ERNGVAPGAQ ILSIKIGDTR 
LSTMETGTGL IRAMIEVINH KCDLVNYSYG EATHWPNSGR ICEVINEAVW KHNIIYVSSA 
GNNGPCLSTV GCPGGTTSSV IGVGAYVSPD MMVAEYSLRE KLPANQYTWS SRGPSADGAL 
GVSISAPGGA IASVPNWTLR GTQLMNGTSM SSPNACGGIA LILSGLKANN IDYTVHSVRR 
ALENTAVKAD NIEVFAQGHG IIQVDKAYDY LVQNTSFANK LGFTVTVGNN RGIYLRDPVQ 
VAAPSDHGVG IEPVFPENTE NSEKISLQLH LALTSNSSWV QCPSHLELMN QCRHINIRVD 
PRGLREGLHY TEVCGYDIAS PNAGPLFRVP ITAVIAAKVN ESSHYDLAFT DVHFKPGQIR 
RHFIEVPEGA TWAEVTVCSC SSEVSAKFVL HAVQLVKQRA YRSHEFYKFC SLPEKGTLTE 
AFPVLGGKAI EFCIARWWAS LSDVNIDYTI SFHGIVCTAP QLNIHASEGI NRFDVQSSLK 
YEDLAPCITL KNWVQTLRPV SAKTKPLGSR DVLPNNRQLY EMVLTYNFHQ PKSGEVTPSC 
PLLCELLYES EFDSQLWIIF DQNKRQMGSG DAYPHQYSLK LEKGDYTIRL QIRHEQISDL 
ERLKDLPFIV SHRLSNTLSL DIHENHSFAL LGKKKSSNLT LPPKYNQPFF VTSLPDDKIP 
KGAGPGCYLA GSLTLSKTEL GKKAGQSAAK RQGKFKKDVI PVHYYLIPPP TKTKNGSKDK 
EKDSEKEKDL KEEFTEALRD LKIQWMTKLD SSDIYNELKE TYPNYLPLYV ARLHQLDAEK 
ERMKRLNEIV DAANAVISHI DQTALAVYIA MKTDPRPDAA TIKNDMDKQK STLVDALCRK 
GCALADHLLH TQAQDGAIST DAEGKEEEGE SPLDSLAETF WETTKWTDLF DNKVLTFAYK 
HALVNKMYGR GLKFATKLVE EKPTKENWKN CIQLMKLLGW THCASFTENW LPIMYPPDYC 
VF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.