Details for: HSP90B1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 820.5973
Cell Significance Index: -127.6400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 492.5419
Cell Significance Index: -124.9300 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 376.7348
Cell Significance Index: -155.2000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 331.2927
Cell Significance Index: -134.5900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 326.7054
Cell Significance Index: -154.2500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 297.4036
Cell Significance Index: -152.9800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 230.8158
Cell Significance Index: -154.8800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 141.9126
Cell Significance Index: -135.4900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 113.7997
Cell Significance Index: -140.3100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 50.8500
Cell Significance Index: -136.2200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 36.1552
Cell Significance Index: -142.6700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 35.4278
Cell Significance Index: -108.8200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 17.6712
Cell Significance Index: -38.6800 - Cell Name: peg cell (CL4033014)
Fold Change: 9.5575
Cell Significance Index: 220.8100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 7.0708
Cell Significance Index: 189.1400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 5.1468
Cell Significance Index: 706.8100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 4.7681
Cell Significance Index: 2603.9800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 4.4790
Cell Significance Index: 128.4000 - Cell Name: kidney cell (CL1000497)
Fold Change: 4.4657
Cell Significance Index: 35.6600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 4.3848
Cell Significance Index: 117.0800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 4.2825
Cell Significance Index: 54.8500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.2254
Cell Significance Index: 197.0100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 4.2233
Cell Significance Index: 219.9900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 3.8339
Cell Significance Index: 80.2500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.7778
Cell Significance Index: 102.8300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 3.4110
Cell Significance Index: 676.9300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 3.1607
Cell Significance Index: 148.5500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 3.1514
Cell Significance Index: 82.8700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 3.1296
Cell Significance Index: 384.8100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 3.1239
Cell Significance Index: 563.1400 - Cell Name: odontoblast (CL0000060)
Fold Change: 2.7167
Cell Significance Index: 348.2700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.3547
Cell Significance Index: 26.7500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 2.0251
Cell Significance Index: 70.3700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.9492
Cell Significance Index: 145.2700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.9075
Cell Significance Index: 54.9600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.6629
Cell Significance Index: 735.2100 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.5276
Cell Significance Index: 197.3600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.2549
Cell Significance Index: 214.2800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.2402
Cell Significance Index: 236.0200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.0741
Cell Significance Index: 116.8300 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.0526
Cell Significance Index: 6.5400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.9724
Cell Significance Index: 68.7700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7908
Cell Significance Index: 158.6300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.7804
Cell Significance Index: 43.7900 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.7718
Cell Significance Index: 8.3900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5802
Cell Significance Index: 208.1100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.4411
Cell Significance Index: 323.3900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.3558
Cell Significance Index: 269.2800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.3145
Cell Significance Index: 11.0500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.2465
Cell Significance Index: 2.2700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.2098
Cell Significance Index: 13.5400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.1873
Cell Significance Index: 5.5000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1676
Cell Significance Index: 115.9000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1082
Cell Significance Index: 5.6800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0571
Cell Significance Index: 0.9500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0436
Cell Significance Index: 1.9700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0217
Cell Significance Index: 3.5300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.0033
Cell Significance Index: -0.0200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0050
Cell Significance Index: -9.4400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0549
Cell Significance Index: -101.2100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0568
Cell Significance Index: -42.0900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0569
Cell Significance Index: -5.8100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0656
Cell Significance Index: -101.0000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0882
Cell Significance Index: -55.0800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.1099
Cell Significance Index: -149.4900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1245
Cell Significance Index: -14.6800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.1585
Cell Significance Index: -100.6800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1873
Cell Significance Index: -105.6500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2245
Cell Significance Index: -25.6300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.2548
Cell Significance Index: -115.6300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2899
Cell Significance Index: -61.0500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3960
Cell Significance Index: -20.5700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.4250
Cell Significance Index: -122.2900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.4444
Cell Significance Index: -43.9700 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.4483
Cell Significance Index: -8.7500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5252
Cell Significance Index: -16.8200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.5357
Cell Significance Index: -14.9700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.5790
Cell Significance Index: -15.5200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.6803
Cell Significance Index: -77.9400 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.7023
Cell Significance Index: -12.9800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.8011
Cell Significance Index: -116.4600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.9169
Cell Significance Index: -106.8500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.9910
Cell Significance Index: -60.9100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -1.0050
Cell Significance Index: -77.1200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.1726
Cell Significance Index: -81.0900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -1.1834
Cell Significance Index: -79.5700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.3398
Cell Significance Index: -139.5100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.3525
Cell Significance Index: -33.8100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.3598
Cell Significance Index: -29.4600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.5185
Cell Significance Index: -32.3400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.6119
Cell Significance Index: -41.1800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.6484
Cell Significance Index: -130.5500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.6950
Cell Significance Index: -106.8300 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -1.8121
Cell Significance Index: -30.5300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.8479
Cell Significance Index: -27.2800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -2.0146
Cell Significance Index: -101.8100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -2.0433
Cell Significance Index: -90.3800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -2.5159
Cell Significance Index: -154.2500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -2.5290
Cell Significance Index: -26.1800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -2.6508
Cell Significance Index: -100.3800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1597284859
Symbol: ENPL_HUMAN
Name: Endoplasmin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2377606
Title: Human homologue of murine tumor rejection antigen gp96: 5'-regulatory and coding regions and relationship to stress-induced proteins.
PubMed ID: 2377606
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2546060
Title: Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors.
PubMed ID: 2546060
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 12475965
Title: A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.
PubMed ID: 12475965
PubMed ID: 12643545
Title: Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.
PubMed ID: 12643545
DOI: 10.1021/pr025562r
PubMed ID: 12754519
Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.
PubMed ID: 12754519
DOI: 10.1038/nbt827
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18663603
Title: Guidelines for the nomenclature of the human heat shock proteins.
PubMed ID: 18663603
PubMed ID: 20865800
Title: Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone.
PubMed ID: 20865800
DOI: 10.1038/ncomms1070
PubMed ID: 17081065
Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
PubMed ID: 17081065
DOI: 10.1021/pr060363j
PubMed ID: 16263699
Title: Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.
PubMed ID: 16263699
PubMed ID: 18264092
Title: OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.
PubMed ID: 18264092
DOI: 10.1038/ncb1689
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23349634
Title: A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
PubMed ID: 23349634
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 29192674
Title: Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway.
PubMed ID: 29192674
DOI: 10.1038/cr.2017.149
PubMed ID: 32272059
Title: A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.
PubMed ID: 32272059
Sequence Information:
- Length: 803
- Mass: 92469
- Checksum: 9BF6705A7A2ED0D0
- Sequence:
MRALWVLGLC CVLLTFGSVR ADDEVDVDGT VEEDLGKSRE GSRTDDEVVQ REEEAIQLDG LNASQIRELR EKSEKFAFQA EVNRMMKLII NSLYKNKEIF LRELISNASD ALDKIRLISL TDENALSGNE ELTVKIKCDK EKNLLHVTDT GVGMTREELV KNLGTIAKSG TSEFLNKMTE AQEDGQSTSE LIGQFGVGFY SAFLVADKVI VTSKHNNDTQ HIWESDSNEF SVIADPRGNT LGRGTTITLV LKEEASDYLE LDTIKNLVKK YSQFINFPIY VWSSKTETVE EPMEEEEAAK EEKEESDDEA AVEEEEEEKK PKTKKVEKTV WDWELMNDIK PIWQRPSKEV EEDEYKAFYK SFSKESDDPM AYIHFTAEGE VTFKSILFVP TSAPRGLFDE YGSKKSDYIK LYVRRVFITD DFHDMMPKYL NFVKGVVDSD DLPLNVSRET LQQHKLLKVI RKKLVRKTLD MIKKIADDKY NDTFWKEFGT NIKLGVIEDH SNRTRLAKLL RFQSSHHPTD ITSLDQYVER MKEKQDKIYF MAGSSRKEAE SSPFVERLLK KGYEVIYLTE PVDEYCIQAL PEFDGKRFQN VAKEGVKFDE SEKTKESREA VEKEFEPLLN WMKDKALKDK IEKAVVSQRL TESPCALVAS QYGWSGNMER IMKAQAYQTG KDISTNYYAS QKKTFEINPR HPLIRDMLRR IKEDEDDKTV LDLAVVLFET ATLRSGYLLP DTKAYGDRIE RMLRLSLNID PDAKVEEEPE EEPEETAEDT TEDTEQDEDE EMDVGTDEEE ETAKESTAEK DEL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.