Details for: LTBP4

Gene ID: 8425

Symbol: LTBP4

Ensembl ID: ENSG00000090006

Description: latent transforming growth factor beta binding protein 4

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 4.32
    Marker Score: 16736
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 3.74
    Marker Score: 3191
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 3.22
    Marker Score: 2122
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 3
    Marker Score: 1250
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.89
    Marker Score: 38167
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.77
    Marker Score: 17997
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 2.76
    Marker Score: 7226
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.39
    Marker Score: 26921
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 2.25
    Marker Score: 559
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 2.23
    Marker Score: 559
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 2.16
    Marker Score: 560
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 2.15
    Marker Score: 8970
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.14
    Marker Score: 9247
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.13
    Marker Score: 2654
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 2.06
    Marker Score: 473
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.03
    Marker Score: 69054
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.91
    Marker Score: 1116
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 1.9
    Marker Score: 1840
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.87
    Marker Score: 1056
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.63
    Marker Score: 1083
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.58
    Marker Score: 11739
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.57
    Marker Score: 2419.5
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 1.53
    Marker Score: 1010
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.5
    Marker Score: 481
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1.48
    Marker Score: 333
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 1.42
    Marker Score: 611
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.4
    Marker Score: 2692
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 1.38
    Marker Score: 926
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 1.36
    Marker Score: 1679
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.34
    Marker Score: 1411
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.34
    Marker Score: 1431
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 1.31
    Marker Score: 1126
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1.3
    Marker Score: 2436
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.27
    Marker Score: 1645
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.27
    Marker Score: 1364
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.26
    Marker Score: 2569
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.26
    Marker Score: 310
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 1.25
    Marker Score: 320
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.25
    Marker Score: 19483
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.23
    Marker Score: 2151
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 1.23
    Marker Score: 464
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.19
    Marker Score: 1345
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.18
    Marker Score: 2012
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.18
    Marker Score: 2784
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 1.16
    Marker Score: 403
  • Cell Name: theca cell (CL0000503)
    Fold Change: 1.16
    Marker Score: 831
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.14
    Marker Score: 1758
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.14
    Marker Score: 2372
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.13
    Marker Score: 3086
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 1.13
    Marker Score: 330
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.12
    Marker Score: 1192
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1.1
    Marker Score: 693
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.05
    Marker Score: 1444
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.05
    Marker Score: 628
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.02
    Marker Score: 6133
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.02
    Marker Score: 4254
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 1
    Marker Score: 364
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71691
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1
    Marker Score: 8557
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1
    Marker Score: 1100
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47914
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.99
    Marker Score: 281
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.99
    Marker Score: 4013.5
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30392
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.97
    Marker Score: 1140.5
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 0.95
    Marker Score: 381
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2399
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.94
    Marker Score: 8965
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 482
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.93
    Marker Score: 459
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 439
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: 0.91
    Marker Score: 239
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2702
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 0.9
    Marker Score: 501
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.9
    Marker Score: 372
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.89
    Marker Score: 288
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 0.89
    Marker Score: 1075
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.89
    Marker Score: 3437
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 0.87
    Marker Score: 499
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.87
    Marker Score: 8214
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.87
    Marker Score: 422
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.87
    Marker Score: 8967
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.86
    Marker Score: 5232
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 310
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.86
    Marker Score: 499
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.86
    Marker Score: 426
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.84
    Marker Score: 4051
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.84
    Marker Score: 292
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.84
    Marker Score: 293
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.84
    Marker Score: 4777
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.83
    Marker Score: 1280
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.83
    Marker Score: 1344
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.83
    Marker Score: 516
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.82
    Marker Score: 904
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.82
    Marker Score: 992
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.81
    Marker Score: 386
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.8
    Marker Score: 610
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.8
    Marker Score: 466
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 0.79
    Marker Score: 177
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.79
    Marker Score: 298

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Other Information

**Key Characteristics:** 1. **ECM Organization:** LTBP4 is significantly expressed in various cell types, including fibroblasts, neural progenitor cells, and mesodermal cells, which are all involved in ECM production and remodeling. Its presence in these cells suggests a critical role in maintaining the integrity and organization of the ECM. 2. **TGF-β Signaling Regulation:** LTBP4 is a key regulator of TGF-β signaling by binding to latent TGF-β and facilitating its activation. This interaction enables TGF-β to signal through Smad proteins, leading to various cellular responses, including cell growth, differentiation, and ECM remodeling. 3. **Cellular Expression:** LTBP4 is expressed in multiple cell types, including fibroblasts, neural progenitor cells, and mesodermal cells, indicating its broad involvement in ECM regulation and TGF-β signaling. 4. **Protein-Protein Interactions:** LTBP4 interacts with various ECM components, including collagen, glycosaminoglycans, and elastic fibers, to modulate their organization and function. **Pathways and Functions:** 1. **Calcium Ion Binding:** LTBP4 interacts with calcium ions, which are essential for ECM organization and function. 2. **Collagen-Containing Extracellular Matrix:** LTBP4 is involved in regulating the organization of collagen-containing ECM components, which is critical for maintaining tissue structure and function. 3. **Elastic Fibre Formation:** LTBP4 plays a role in the formation and organization of elastic fibers, which are essential for maintaining tissue elasticity and resilience. 4. **Extracellular Matrix Organization:** LTBP4 is involved in regulating the organization of the ECM, including the arrangement of ECM components and the formation of microfibrils. 5. **Protein Binding:** LTBP4 interacts with various ECM components and signaling molecules, including TGF-β, to modulate their function and signaling. 6. **Signaling by TGF-β Receptor Complex:** LTBP4 is involved in regulating TGF-β signaling through the TGF-β receptor complex, which is critical for various cellular responses. **Clinical Significance:** 1. **Cancer Progression:** Alterations in LTBP4 expression and function have been linked to cancer progression, including tumor growth, invasion, and metastasis. 2. **Fibrotic Diseases:** LTBP4 is involved in regulating ECM organization and function, which is critical for maintaining tissue health. Alterations in LTBP4 expression and function have been linked to fibrotic diseases, including pulmonary fibrosis and liver fibrosis. 3. **Regenerative Medicine:** LTBP4 plays a critical role in regulating ECM organization and function, making it a potential target for regenerative medicine applications, including tissue engineering and wound healing. 4. **Inflammatory Diseases:** LTBP4 is involved in regulating TGF-β signaling, which is critical for maintaining tissue homeostasis. Alterations in LTBP4 expression and function have been linked to inflammatory diseases, including rheumatoid arthritis and atherosclerosis. In conclusion, LTBP4 is a multifunctional protein that plays a critical role in regulating ECM organization and TGF-β signaling. Its involvement in various cellular processes and diseases highlights the importance of LTBP4 in maintaining tissue health and homeostasis. Further research is needed to fully elucidate the mechanisms of LTBP4 and its clinical significance.

Genular Protein ID: 3131286244

Symbol: LTBP4_HUMAN

Name: Latent-transforming growth factor beta-binding protein 4

UniProtKB Accession Codes:

Q8N2S1 O00508 O75412 O75413

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 CarbonylDB 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 6 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 2 RefSeq 3 SAM 1 SMART 2 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9271198

Title: Sequence and expression of a novel member (LTBP-4) of the family of latent transforming growth factor-beta binding proteins.

PubMed ID: 9271198

DOI: 10.1016/s0014-5793(97)00685-6

PubMed ID: 9660815

Title: Identification and characterization of a new latent transforming growth factor-beta-binding protein, LTBP-4.

PubMed ID: 9660815

DOI: 10.1074/jbc.273.29.18459

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 16157329

Title: Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.

PubMed ID: 16157329

DOI: 10.1016/j.yexcr.2005.08.008

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27339457

Title: Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.

PubMed ID: 27339457

DOI: 10.1016/j.matbio.2016.06.003

PubMed ID: 19836010

Title: Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development.

PubMed ID: 19836010

DOI: 10.1016/j.ajhg.2009.09.013

PubMed ID: 23440719

Title: LTBP4 genotype predicts age of ambulatory loss in Duchenne muscular dystrophy.

PubMed ID: 23440719

DOI: 10.1002/ana.23819

PubMed ID: 25641372

Title: Genetic modifiers of ambulation in the Cooperative International Neuromuscular Research Group Duchenne Natural History Study.

PubMed ID: 25641372

DOI: 10.1002/ana.24370

Sequence Information:

  • Length: 1624
  • Mass: 173435
  • Checksum: 75682D1F6E40657A
  • Sequence:
    • MPRPGTSGRR PLLLVLLLPL FAAATSAASP SPSPSQVVEV PGVPSRPASV AVCRCCPGQT 
SRRSRCIRAF CRVRSCQPKK CAGPQRCLNP VPAVPSPSPS VRKRQVSLNW QPLTLQEARA 
LLKRRRPRGP GGRGLLRRRP PQRAPAGKAP VLCPLICHNG GVCVKPDRCL CPPDFAGKFC 
QLHSSGARPP APAVPGLTRS VYTMPLANHR DDEHGVASMV SVHVEHPQEA SVVVHQVERV 
SGPWEEADAE AVARAEAAAR AEAAAPYTVL AQSAPREDGY SDASGFGYCF RELRGGECAS 
PLPGLRTQEV CCRGAGLAWG VHDCQLCSER LGNSERVSAP DGPCPTGFER VNGSCEDVDE 
CATGGRCQHG ECANTRGGYT CVCPDGFLLD SSRSSCISQH VISEAKGPCF RVLRDGGCSL 
PILRNITKQI CCCSRVGKAW GRGCQLCPPF GSEGFREICP AGPGYHYSAS DLRYNTRPLG 
QEPPRVSLSQ PRTLPATSRP SAGFLPTHRL EPRPEPRPDP RPGPELPLPS IPAWTGPEIP 
ESGPSSGMCQ RNPQVCGPGR CISRPSGYTC ACDSGFRLSP QGTRCIDVDE CRRVPPPCAP 
GRCENSPGSF RCVCGPGFRA GPRAAECLDV DECHRVPPPC DLGRCENTPG SFLCVCPAGY 
QAAPHGASCQ DVDECTQSPG LCGRGACKNL PGSFRCVCPA GFRGSACEED VDECAQEPPP 
CGPGRCDNTA GSFHCACPAG FRSRGPGAPC QDVDECARSP PPCTYGRCEN TEGSFQCVCP 
MGFQPNTAGS ECEDVDECEN HLACPGQECV NSPGSFQCRT CPSGHHLHRG RCTDVDECSS 
GAPPCGPHGH CTNTEGSFRC SCAPGYRAPS GRPGPCADVN ECLEGDFCFP HGECLNTDGS 
FACTCAPGYR PGPRGASCLD VDECSEEDLC QSGICTNTDG SFECICPPGH RAGPDLASCL 
DVDECRERGP ALCGSQRCEN SPGSYRCVRD CDPGYHAGPE GTCDDVDECQ EYGPEICGAQ 
RCENTPGSYR CTPACDPGYQ PTPGGGCQDV DECRNRSFCG AHAVCQNLPG SFQCLCDQGY 
EGARDGRHCV DVNECETLQG VCGAALCENV EGSFLCVCPN SPEEFDPMTG RCVPPRTSAG 
TFPGSQPQAP ASPVLPARPP PPPLPRRPST PRQGPVGSGR RECYFDTAAP DACDNILARN 
VTWQECCCTV GEGWGSGCRI QQCPGTETAE YQSLCPHGRG YLAPSGDLSL RRDVDECQLF 
RDQVCKSGVC VNTAPGYSCY CSNGYYYHTQ RLECIDNDEC ADEEPACEGG RCVNTVGSYH 
CTCEPPLVLD GSQRRCVSNE SQSLDDNLGV CWQEVGADLV CSHPRLDRQA TYTECCCLYG 
EAWGMDCALC PAQDSDDFEA LCNVLRPPAY SPPRPGGFGL PYEYGPDLGP PYQGLPYGPE 
LYPPPALPYD PYPPPPGPFA RREAPYGAPR FDMPDFEDDG GPYGESEAPA PPGPGTRWPY 
RSRDTRRSFP EPEEPPEGGS YAGSLAEPYE ELEAEECGIL DGCTNGRCVR VPEGFTCRCF 
DGYRLDMTRM ACVDINECDE AEAASPLCVN ARCLNTDGSF RCICRPGFAP THQPHHCAPA 
RPRA

Genular Protein ID: 3316994112

Symbol: A0A0C4DH07_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DH07

Database IDs:

ARBA 9 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 8 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 8 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 3 Proteomes 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 3 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1587
  • Mass: 169456
  • Checksum: C221635636D13889
  • Sequence:
    • MGDVKALLFV AAARARRLGG AAASESLAVS EAFCRVRSCQ PKKCAGPQRC LNPVPAVPSP 
SPSVRKRQVS LNWQPLTLQE ARALLKRRRP RGPGGRGLLR RRPPQRAPAG KAPVLCPLIC 
HNGGVCVKPD RCLCPPDFAG KFCQLHSSGA RPPAPAVPGL TRSVYTMPLA NHRDDEHGVA 
SMVSVHVEHP QEASVVVHQV ERVSGPWEEA DAEAVARAEA AARAEAAAPY TVLAQSAPRE 
DGYSDASGFG YCFRELRGGE CASPLPGLRT QEVCCRGAGL AWGVHDCQLC SERLGNSERV 
SAPDGPCPTG FERVNGSCED VDECATGGRC QHGECANTRG GYTCVCPDGF LLDSSRSSCI 
SQHVISEAKG PCFRVLRDGG CSLPILRNIT KQICCCSRVG KAWGRGCQLC PPFGSEGFRE 
ICPAGPGYHY SASDLRYNTR PLGQEPPRVS LSQPRTLPAT SRPSAGFLPT HRLEPRPEPR 
PDPRPGPELP LPSIPAWTGP EIPESGPSSG MCQRNPQVCG PGRCISRPSG YTCACDSGFR 
LSPQGTRCID VDECRRVPPP CAPGRCENSP GSFRCVCGPG FRAGPRAAEC LDVDECHRVP 
PPCDLGRCEN TPGSFLCVCP AGYQAAPHGA SCQDVDECTQ SPGLCGRGAC KNLPGSFRCV 
CPAGFRGSAC EEDVDECAQE PPPCGPGRCD NTAGSFHCAC PAGFRSRGPG APCQDVDECA 
RSPPPCTYGR CENTEGSFQC VCPMGFQPNT AGSECEDVDE CENHLACPGQ ECVNSPGSFQ 
CRTCPSGHHL HRGRCTDVDE CSSGAPPCGP HGHCTNTEGS FRCSCAPGYR APSGRPGPCA 
DVNECLEGDF CFPHGECLNT DGSFACTCAP GYRPGPRGAS CLDVDECSEE DLCQSGICTN 
TDGSFECICP PGHRAGPDLA SCLDVDECRE RGPALCGSQR CENSPGSYRC VRDCDPGYHA 
GPEGTCDDVD ECQEYGPEIC GAQRCENTPG SYRCTPACDP GYQPTPGGGC QDVDECRNRS 
FCGAHAVCQN LPGSFQCLCD QGYEGARDGR HCVDVNECET LQGVCGAALC ENVEGSFLCV 
CPNSPEEFDP MTGRCVPPRT SAGTFPGSQP QAPASPVLPA RPPPPPLPRR PSTPRQGPVG 
SGRRECYFDT AAPDACDNIL ARNVTWQECC CTVGEGWGSG CRIQQCPGTE TAEYQSLCPH 
GRGYLAPSGD LSLRRDVDEC QLFRDQVCKS GVCVNTAPGY SCYCSNGYYY HTQRLECIDN 
DECADEEPAC EGGRCVNTVG SYHCTCEPPL VLDGSQRRCV SNESQSLDDN LGVCWQEVGA 
DLVCSHPRLD RQATYTECCC LYGEAWGMDC ALCPAQDSDD FEALCNVLRP PAYSPPRPGG 
FGLPYEYGPD LGPPYQGLPY GPELYPPPAL PYDPYPPPPG PFARREAPYG APRFDMPDFE 
DDGGPYGESE APAPPGPGTR WPYRSRDTRR SFPEPEEPPE GGSYAGSLAE PYEELEAEEC 
GILDGCTNGR CVRVPEGFTC RCFDGYRLDM TRMACVDINE CDEAEAASPL CVNARCLNTD 
GSFRCICRPG FAPTHQPHHC APARPRA

Genular Protein ID: 1219416924

Symbol: B3KXY6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KXY6

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 3 SAM 1 SMART 2 SUPFAM 3

Sequence Information:

  • Length: 844
  • Mass: 90751
  • Checksum: 05729D3A8F202D7A
  • Sequence:
    • MGFQPNTAGS ECEDVDECEN HLACPGQECV NSPGSFQCRT CPSGHHLHRG RCTDVDECSS 
GAPPCGPHGH CTNTEGSFRC SCAPGYRAPS GRPGPCADVN ECLEGDFCFP HGECLNTDGS 
FACTCAPGYR PGPRGASCLD VDECSEEDLC QSGICTNTDG SFECICPPGH RAGPDLASCL 
DVDECRERGP ALCGSQRCEN SPGSYRCVRD CDPGYHAGPE GTCDDVDECQ EYGPEICGAQ 
RCENTPGSYR CTPACDPGYQ PTPGGGCQDV DECRNRSFCG AHAVCQNLPG SFQCLCDQGY 
EGARDGRHCV DVNECETLQG VCGAALCENV EGSFLCVCPN SPEEFDPMTG RCVPPRTSAG 
TFPGSQPQAP ASPVLPARPP PPPLPRRPST PRQGPVGSGR RECYFDTAAP DACDNILARN 
VTWQECCCTV GEGWGSGCRI QQCPGTETAE YQSLCPHGRG YLAPSGDLSL RRDVDECQLF 
RDQVCKSGVC VNTAPGYSCY CSNGYYYHTQ RLECIDNDEC ADEEPACEGG RCVNTVGSYH 
CTCEPPLVLD GSQRRCVSNE SQSLDDNLGV CWQEVGADLV CSHPRLDRQA TYTECCCLYG 
EAWGMDCALC PAQDSDDFEA LCNVLRPPAY SPPRPGGFGL PYEYGPDLGP PYQGLPYGPE 
LYPPPALPYD PYPPPPGPFA RREAPYGAPR FDMPDFEDDG GPYGESEAPA PPGPGTRWPY 
RSRDTRRSFP EPEEPPEGGS YAGSLAEPYE ELEAEECGIL DGCTNGRCVR VPEGFTCRCF 
DGYRLDMTRM ACVDINECDE AEAASPLCVN ARCLNTDGSF RCICRPGFAP THQPHHCAPA 
RPRA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.