Details for: CILP

Gene ID: 8483

Symbol: CILP

Ensembl ID: ENSG00000138615

Description: cartilage intermediate layer protein

Associated with

  • Signaling by receptor tyrosine kinases
    (R-HSA-9006934)
  • Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
    (R-HSA-2404192)
  • Signal transduction
    (R-HSA-162582)
  • Alkaline phosphatase activity
    (GO:0004035)
  • Collagen-containing extracellular matrix
    (GO:0062023)
  • Dinucleotide phosphatase activity
    (GO:0004551)
  • Extracellular exosome
    (GO:0070062)
  • Extracellular matrix structural constituent
    (GO:0005201)
  • Extracellular space
    (GO:0005615)
  • Negative regulation of gene expression
    (GO:0010629)
  • Negative regulation of insulin-like growth factor receptor signaling pathway
    (GO:0043569)
  • Negative regulation of smad protein signal transduction
    (GO:0060392)
  • Negative regulation of transforming growth factor beta receptor signaling pathway
    (GO:0030512)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 19.9948
    Cell Significance Index: -9.4400
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 5.2621
    Cell Significance Index: 35.6500
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.9298
    Cell Significance Index: 30.9600
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.3610
    Cell Significance Index: 6.7900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.1040
    Cell Significance Index: 17.0800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.9497
    Cell Significance Index: 58.2300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.5503
    Cell Significance Index: 10.7400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4404
    Cell Significance Index: 11.0100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4240
    Cell Significance Index: 9.1900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2977
    Cell Significance Index: 13.5000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.2860
    Cell Significance Index: 14.4500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2220
    Cell Significance Index: 6.3600
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.1904
    Cell Significance Index: 2.6700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1656
    Cell Significance Index: 149.5200
  • Cell Name: collagen secreting cell (CL0000667)
    Fold Change: 0.1365
    Cell Significance Index: 0.7600
  • Cell Name: fibroblast of the aortic adventitia (CL0002547)
    Fold Change: 0.1130
    Cell Significance Index: 1.1400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0799
    Cell Significance Index: 7.9100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0705
    Cell Significance Index: 11.4700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0653
    Cell Significance Index: 12.4300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0564
    Cell Significance Index: 7.7400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0471
    Cell Significance Index: 8.4900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0371
    Cell Significance Index: 25.6600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0140
    Cell Significance Index: 0.3600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0033
    Cell Significance Index: 0.4200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0016
    Cell Significance Index: 0.5900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0006
    Cell Significance Index: -0.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0043
    Cell Significance Index: -8.1100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0067
    Cell Significance Index: -0.1400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0100
    Cell Significance Index: -18.5100
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0107
    Cell Significance Index: -0.1300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0113
    Cell Significance Index: -7.1800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0117
    Cell Significance Index: -17.9400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0121
    Cell Significance Index: -8.8900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0144
    Cell Significance Index: -19.5200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0147
    Cell Significance Index: -11.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0192
    Cell Significance Index: -10.5000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0197
    Cell Significance Index: -14.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0216
    Cell Significance Index: -9.8200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0216
    Cell Significance Index: -6.2100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0259
    Cell Significance Index: -14.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0391
    Cell Significance Index: -7.8500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0403
    Cell Significance Index: -4.9600
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.0425
    Cell Significance Index: -0.4100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0457
    Cell Significance Index: -9.0600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0458
    Cell Significance Index: -1.3200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0495
    Cell Significance Index: -7.2000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0503
    Cell Significance Index: -1.3700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0740
    Cell Significance Index: -0.8100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0794
    Cell Significance Index: -13.5700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0823
    Cell Significance Index: -10.6300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0854
    Cell Significance Index: -9.2900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0881
    Cell Significance Index: -10.2700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0925
    Cell Significance Index: -9.4500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0925
    Cell Significance Index: -19.4900
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.0925
    Cell Significance Index: -1.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0954
    Cell Significance Index: -4.4900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0959
    Cell Significance Index: -2.6800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0981
    Cell Significance Index: -2.5800
  • Cell Name: muscle fibroblast (CL1001609)
    Fold Change: -0.1012
    Cell Significance Index: -0.6200
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.1041
    Cell Significance Index: -1.1500
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.1065
    Cell Significance Index: -0.6700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1091
    Cell Significance Index: -11.3600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1142
    Cell Significance Index: -7.9000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1211
    Cell Significance Index: -13.8700
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1288
    Cell Significance Index: -1.8300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1375
    Cell Significance Index: -3.3300
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.1397
    Cell Significance Index: -2.4000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1407
    Cell Significance Index: -10.4900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1423
    Cell Significance Index: -7.4100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1448
    Cell Significance Index: -11.1100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1490
    Cell Significance Index: -17.5700
  • Cell Name: myoblast (CL0000056)
    Fold Change: -0.1496
    Cell Significance Index: -1.4700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1568
    Cell Significance Index: -10.5400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1580
    Cell Significance Index: -6.4800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1601
    Cell Significance Index: -10.3300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1603
    Cell Significance Index: -6.9700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1721
    Cell Significance Index: -3.6700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1801
    Cell Significance Index: -4.1600
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.1971
    Cell Significance Index: -1.2200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2014
    Cell Significance Index: -9.3900
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.2044
    Cell Significance Index: -2.7800
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.2151
    Cell Significance Index: -1.5500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2163
    Cell Significance Index: -3.6200
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.2201
    Cell Significance Index: -2.9700
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.2263
    Cell Significance Index: -2.2800
  • Cell Name: chondroblast (CL0000058)
    Fold Change: -0.2266
    Cell Significance Index: -1.3300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2276
    Cell Significance Index: -12.7700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2317
    Cell Significance Index: -8.0500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2403
    Cell Significance Index: -2.7300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2429
    Cell Significance Index: -7.1600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2444
    Cell Significance Index: -3.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2451
    Cell Significance Index: -10.8400
  • Cell Name: articular chondrocyte (CL1001607)
    Fold Change: -0.2454
    Cell Significance Index: -1.3300
  • Cell Name: Langerhans cell (CL0000453)
    Fold Change: -0.2612
    Cell Significance Index: -2.4900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2633
    Cell Significance Index: -9.2300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.2683
    Cell Significance Index: -6.6900
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.2691
    Cell Significance Index: -2.9500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2861
    Cell Significance Index: -15.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2868
    Cell Significance Index: -10.8600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2927
    Cell Significance Index: -2.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CILP is a small, secreted protein that belongs to the family of ECM structural constituents. It is primarily expressed in enterocytes, skeletal muscle fibroblasts, and other cell types involved in tissue repair and maintenance. CILP exhibits a unique ability to modulate the activity of various enzymes, including alkaline phosphatase and dinucleotide phosphatase, thereby influencing the degradation and synthesis of ECM components. **Pathways and Functions:** CILP is involved in several critical signaling pathways, including: 1. **Negative regulation of gene expression**: CILP acts as a co-repressor, inhibiting the transcription of target genes involved in cell growth, differentiation, and survival. 2. **Negative regulation of insulin-like growth factor receptor signaling pathway**: CILP modulates the activity of IGF-1R, thereby regulating cell proliferation, differentiation, and survival. 3. **Negative regulation of smad protein signal transduction**: CILP inhibits the phosphorylation and activation of smad proteins, which are key mediators of TGF-β signaling. 4. **Negative regulation of transforming growth factor beta receptor signaling pathway**: CILP modulates the activity of TGF-β receptors, influencing cell growth, differentiation, and survival. CILP also plays a role in regulating the activity of receptor tyrosine kinases (RTKs) and type 1 IGF-1 receptor (IGF-1R), which are involved in cell proliferation, differentiation, and survival. **Clinical Significance:** Dysregulation of CILP has been implicated in various diseases, including: 1. **Cancer**: CILP overexpression has been linked to tumorigenesis and metastasis in various cancers, including colorectal, breast, and prostate cancer. 2. **Metabolic disorders**: CILP has been implicated in the regulation of glucose and lipid metabolism, and its dysregulation may contribute to the development of metabolic disorders, such as insulin resistance and type 2 diabetes. 3. **Musculoskeletal disorders**: CILP plays a role in regulating ECM homeostasis, and its dysregulation may contribute to the development of musculoskeletal disorders, such as osteoarthritis and rickets. In conclusion, CILP is a multifunctional protein that plays a critical role in regulating ECM homeostasis and signaling pathways. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms underlying CILP function and its clinical significance.

Genular Protein ID: 4069158176

Symbol: CILP1_HUMAN

Name: Cartilage intermediate layer protein 1

UniProtKB Accession Codes:

O75339 B2R8F7 Q6UW99 Q8IYI5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 1 GO 7 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9722584

Title: Cloning and deduced amino acid sequence of a novel cartilage protein (CILP) identifies a proform including a nucleotide pyrophosphohydrolase.

PubMed ID: 9722584

DOI: 10.1074/jbc.273.36.23469

PubMed ID: 10319588

Title: Genomic organization, mapping, and polymorphisms of the gene encoding human cartilage intermediate layer protein (CILP).

PubMed ID: 10319588

DOI: 10.1007/s100380050143

PubMed ID: 10601732

Title: The human CILP gene: exon/intron organization and chromosomal mapping.

PubMed ID: 10601732

DOI: 10.1016/s0945-053x(99)00035-9

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9722583

Title: A novel cartilage protein (CILP) present in the mid-zone of human articular cartilage increases with age.

PubMed ID: 9722583

DOI: 10.1074/jbc.273.36.23463

PubMed ID: 12483726

Title: Up-regulated expression of cartilage intermediate-layer protein and ANK in articular hyaline cartilage from patients with calcium pyrophosphate dihydrate crystal deposition disease.

PubMed ID: 12483726

DOI: 10.1002/art.10632

PubMed ID: 11315923

Title: Implication of cartilage intermediate layer protein in cartilage destruction in subsets of patients with osteoarthritis and rheumatoid arthritis.

PubMed ID: 11315923

DOI: 10.1002/1529-0131(200104)44:4<838::aid-anr140>3.0.co;2-c

PubMed ID: 12746903

Title: One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist.

PubMed ID: 12746903

DOI: 10.1002/art.10927

PubMed ID: 14962958

Title: Characterisation of cartilage intermediate layer protein (CILP)-induced arthropathy in mice.

PubMed ID: 14962958

DOI: 10.1136/ard.2003.008045

PubMed ID: 15378262

Title: The prevalence of autoantibodies against cartilage intermediate layer protein, YKL-39, osteopontin, and cyclic citrullinated peptide in patients with early-stage knee osteoarthritis: evidence of a variety of autoimmune processes.

PubMed ID: 15378262

DOI: 10.1007/s00296-004-0497-2

PubMed ID: 15864306

Title: A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.

PubMed ID: 15864306

DOI: 10.1038/ng1557

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

Sequence Information:

  • Length: 1184
  • Mass: 132565
  • Checksum: 190B0316404D3B84
  • Sequence:
    • MVGTKAWVFS FLVLEVTSVL GRQTMLTQSV RRVQPGKKNP SIFAKPADTL ESPGEWTTWF 
NIDYPGGKGD YERLDAIRFY YGDRVCARPL RLEARTTDWT PAGSTGQVVH GSPREGFWCL 
NREQRPGQNC SNYTVRFLCP PGSLRRDTER IWSPWSPWSK CSAACGQTGV QTRTRICLAE 
MVSLCSEASE EGQHCMGQDC TACDLTCPMG QVNADCDACM CQDFMLHGAV SLPGGAPASG 
AAIYLLTKTP KLLTQTDSDG RFRIPGLCPD GKSILKITKV KFAPIVLTMP KTSLKAATIK 
AEFVRAETPY MVMNPETKAR RAGQSVSLCC KATGKPRPDK YFWYHNDTLL DPSLYKHESK 
LVLRKLQQHQ AGEYFCKAQS DAGAVKSKVA QLIVIASDET PCNPVPESYL IRLPHDCFQN 
ATNSFYYDVG RCPVKTCAGQ QDNGIRCRDA VQNCCGISKT EEREIQCSGY TLPTKVAKEC 
SCQRCTETRS IVRGRVSAAD NGEPMRFGHV YMGNSRVSMT GYKGTFTLHV PQDTERLVLT 
FVDRLQKFVN TTKVLPFNKK GSAVFHEIKM LRRKKPITLE AMETNIIPLG EVVGEDPMAE 
LEIPSRSFYR QNGEPYIGKV KASVTFLDPR NISTATAAQT DLNFINDEGD TFPLRTYGMF 
SVDFRDEVTS EPLNAGKVKV HLDSTQVKMP EHISTVKLWS LNPDTGLWEE EGDFKFENQR 
RNKREDRTFL VGNLEIRERR LFNLDVPESR RCFVKVRAYR SERFLPSEQI QGVVISVINL 
EPRTGFLSNP RAWGRFDSVI TGPNGACVPA FCDDQSPDAY SAYVLASLAG EELQAVESSP 
KFNPNAIGVP QPYLNKLNYR RTDHEDPRVK KTAFQISMAK PRPNSAEESN GPIYAFENLR 
ACEEAPPSAA HFRFYQIEGD RYDYNTVPFN EDDPMSWTED YLAWWPKPME FRACYIKVKI 
VGPLEVNVRS RNMGGTHRQT VGKLYGIRDV RSTRDRDQPN VSAACLEFKC SGMLYDQDRV 
DRTLVKVIPQ GSCRRASVNP MLHEYLVNHL PLAVNNDTSE YTMLAPLDPL GHNYGIYTVT 
DQDPRTAKEI ALGRCFDGTS DGSSRIMKSN VGVALTFNCV ERQVGRQSAF QYLQSTPAQS 
PAAGTVQGRV PSRRQQRASR GGQRQGGVVA SLRFPRVAQQ PLIN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.