Details for: NOP14

Gene ID: 8602

Symbol: NOP14

Ensembl ID: ENSG00000087269

Description: NOP14 nucleolar protein

Associated with

  • Major pathway of rrna processing in the nucleolus and cytosol
    (R-HSA-6791226)
  • Metabolism of rna
    (R-HSA-8953854)
  • Rrna modification in the nucleus and cytosol
    (R-HSA-6790901)
  • Rrna processing in the nucleus and cytosol
    (R-HSA-8868773)
  • 90s preribosome
    (GO:0030686)
  • Endonucleolytic cleavage in 5'-ets of tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000480)
  • Endonucleolytic cleavage in its1 to separate ssu-rrna from 5.8s rrna and lsu-rrna from tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000447)
  • Endonucleolytic cleavage to generate mature 5'-end of ssu-rrna from (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000472)
  • Enzyme binding
    (GO:0019899)
  • Maturation of ssu-rrna
    (GO:0030490)
  • Maturation of ssu-rrna from tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000462)
  • Membrane
    (GO:0016020)
  • Noc4p-nop14p complex
    (GO:0030692)
  • Nucleolus
    (GO:0005730)
  • Nucleoplasm
    (GO:0005654)
  • Ribosomal small subunit biogenesis
    (GO:0042274)
  • Rna binding
    (GO:0003723)
  • Rrna processing
    (GO:0006364)
  • Small-subunit processome
    (GO:0032040)
  • Snorna binding
    (GO:0030515)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 114.5969
    Cell Significance Index: -17.8300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 66.1165
    Cell Significance Index: -16.7700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 53.6961
    Cell Significance Index: -22.1200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 46.1533
    Cell Significance Index: -21.7900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 43.0762
    Cell Significance Index: -17.5000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 18.7956
    Cell Significance Index: -17.9500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.1279
    Cell Significance Index: -19.8900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.4173
    Cell Significance Index: -19.8700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.1976
    Cell Significance Index: -20.5100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.0697
    Cell Significance Index: -12.5000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.6416
    Cell Significance Index: -7.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.3941
    Cell Significance Index: 137.9100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.2614
    Cell Significance Index: 17.2100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.2430
    Cell Significance Index: 64.5700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.0608
    Cell Significance Index: 28.4300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0403
    Cell Significance Index: 127.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.0320
    Cell Significance Index: 186.0300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9526
    Cell Significance Index: 860.0900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.9174
    Cell Significance Index: 24.9700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.8997
    Cell Significance Index: 8.2900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.8686
    Cell Significance Index: 23.2400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7731
    Cell Significance Index: 22.2800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.6105
    Cell Significance Index: 9.8000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5584
    Cell Significance Index: 38.6200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5323
    Cell Significance Index: 27.7300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4475
    Cell Significance Index: 31.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4277
    Cell Significance Index: 84.8700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4115
    Cell Significance Index: 26.5500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.3914
    Cell Significance Index: 10.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3554
    Cell Significance Index: 48.8000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3535
    Cell Significance Index: 193.0400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3256
    Cell Significance Index: 14.7600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3117
    Cell Significance Index: 137.8000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.3038
    Cell Significance Index: 14.2800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2975
    Cell Significance Index: 35.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2833
    Cell Significance Index: 56.8200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2534
    Cell Significance Index: 5.4900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2477
    Cell Significance Index: 7.1000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1793
    Cell Significance Index: 34.1300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1774
    Cell Significance Index: 63.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1594
    Cell Significance Index: 7.4300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1487
    Cell Significance Index: 102.8200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1295
    Cell Significance Index: 16.7300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0864
    Cell Significance Index: 6.6300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0767
    Cell Significance Index: 12.4800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0740
    Cell Significance Index: 2.6000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0650
    Cell Significance Index: 1.9100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0174
    Cell Significance Index: 26.7500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0154
    Cell Significance Index: 28.3700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0134
    Cell Significance Index: 25.2000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0131
    Cell Significance Index: 0.2800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0115
    Cell Significance Index: 1.9700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0028
    Cell Significance Index: 0.2100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0003
    Cell Significance Index: 0.3400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0081
    Cell Significance Index: -5.9600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0105
    Cell Significance Index: -6.6500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0119
    Cell Significance Index: -9.0400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0178
    Cell Significance Index: -0.5700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0227
    Cell Significance Index: -16.8000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0230
    Cell Significance Index: -10.4500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0286
    Cell Significance Index: -0.8000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0353
    Cell Significance Index: -19.9200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0377
    Cell Significance Index: -4.8300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0384
    Cell Significance Index: -24.0000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0394
    Cell Significance Index: -4.0200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0415
    Cell Significance Index: -2.6200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0495
    Cell Significance Index: -7.1900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0533
    Cell Significance Index: -2.6900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0565
    Cell Significance Index: -16.2700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0617
    Cell Significance Index: -1.4300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0673
    Cell Significance Index: -7.8400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1053
    Cell Significance Index: -5.9100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1096
    Cell Significance Index: -2.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1115
    Cell Significance Index: -23.4900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1127
    Cell Significance Index: -6.9300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1146
    Cell Significance Index: -13.1300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1490
    Cell Significance Index: -0.9000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1569
    Cell Significance Index: -6.9400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1737
    Cell Significance Index: -3.3900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1776
    Cell Significance Index: -4.4400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1788
    Cell Significance Index: -18.6200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1881
    Cell Significance Index: -11.5300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2033
    Cell Significance Index: -13.6700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2051
    Cell Significance Index: -4.3900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2163
    Cell Significance Index: -17.1300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2314
    Cell Significance Index: -8.0400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2365
    Cell Significance Index: -6.2200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2430
    Cell Significance Index: -9.2000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2445
    Cell Significance Index: -4.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2592
    Cell Significance Index: -13.6100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.2962
    Cell Significance Index: -3.2200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3007
    Cell Significance Index: -7.7300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3063
    Cell Significance Index: -3.4800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3355
    Cell Significance Index: -5.6200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3621
    Cell Significance Index: -7.5800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3947
    Cell Significance Index: -7.3000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4507
    Cell Significance Index: -15.7900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.4565
    Cell Significance Index: -18.7100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.4823
    Cell Significance Index: -8.1300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4892
    Cell Significance Index: -17.9600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NOP14 is a nucleolar protein that belongs to the Nop complex, a group of proteins involved in ribosome biogenesis and function. The NOP14 protein is characterized by its ability to bind to rRNA precursors and participate in the endonucleolytic cleavage of these precursors, generating mature rRNA molecules. This process is essential for the assembly and maturation of ribosomes, which are composed of rRNA and proteins. NOP14 is also involved in the regulation of rRNA processing and modification, which are critical for ribosome function and protein synthesis. **Pathways and Functions** NOP14 is involved in several key pathways and processes, including: 1. **Ribosome biogenesis**: NOP14 is essential for the maturation of the small subunit of ribosomes, which are critical for protein synthesis. 2. **Endonucleolytic cleavage**: NOP14 participates in the endonucleolytic cleavage of rRNA precursors, generating mature rRNA molecules. 3. **RNA processing**: NOP14 is involved in the regulation of rRNA processing and modification, which are critical for ribosome function and protein synthesis. 4. **Nucleolus**: NOP14 is localized to the nucleolus, a specialized region within the nucleus responsible for ribosome biogenesis and function. **Clinical Significance** Dysregulation of NOP14 has been implicated in various diseases, including: 1. **Neurodegenerative disorders**: NOP14 has been shown to play a critical role in the regulation of rRNA processing and modification, which are essential for neuronal function and survival. 2. **Cancer**: NOP14 has been implicated in the regulation of rRNA processing and modification, which can contribute to cancer development and progression. 3. **Ribosomopathies**: NOP14 mutations have been associated with ribosomopathies, a group of disorders characterized by defects in ribosome function and protein synthesis. In summary, NOP14 is a critical component of the nucleolus, involved in the maturation of ribosomes and regulation of rRNA processing and modification. Dysregulation of NOP14 has been implicated in various diseases, highlighting the importance of this gene in maintaining cellular homeostasis and normal physiological function.

Genular Protein ID: 1824727773

Symbol: NOP14_HUMAN

Name: Nucleolar protein 14

UniProtKB Accession Codes:

P78316 D3DVR6 Q7LGI5 Q7Z6K0 Q8TBR6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 3 ExpressionAtlas 1 GO 16 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9661704

Title: Exon trapping and sequence-based methods of gene finding in transcript mapping of human 4p16.3.

PubMed ID: 9661704

DOI: 10.1007/bf02673751

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9734812

Title: The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3.

PubMed ID: 9734812

DOI: 10.1093/dnares/5.3.177

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 857
  • Mass: 97668
  • Checksum: CDADFB91083DBB75
  • Sequence:
    • MAKAKKVGAR RKASGAPAGA RGGPAKANSN PFEVKVNRQK FQILGRKTRH DVGLPGVSRA 
RALRKRTQTL LKEYKERDKS NVFRDKRFGE YNSNMSPEEK MMKRFALEQQ RHHEKKSIYN 
LNEDEELTHY GQSLADIEKH NDIVDSDSDA EDRGTLSAEL TAAHFGGGGG LLHKKTQQEG 
EEREKPKSRK ELIEELIAKS KQEKRERQAQ REDALELTEK LDQDWKEIQT LLSHKTPKSE 
NRDKKEKPKP DAYDMMVREL GFEMKAQPSN RMKTEAELAK EEQEHLRKLE AERLRRMLGK 
DEDENVKKPK HMSADDLNDG FVLDKDDRRL LSYKDGKMNV EEDVQEEQSK EASDPESNEE 
EGDSSGGEDT EESDSPDSHL DLESNVESEE ENEKPAKEQR QTPGKGLISG KERAGKATRD 
ELPYTFAAPE SYEELRSLLL GRSMEEQLLV VERIQKCNHP SLAEGNKAKL EKLFGFLLEY 
VGDLATDDPP DLTVIDKLVV HLYHLCQMFP ESASDAIKFV LRDAMHEMEE MIETKGRAAL 
PGLDVLIYLK ITGLLFPTSD FWHPVVTPAL VCLSQLLTKC PILSLQDVVK GLFVCCLFLE 
YVALSQRFIP ELINFLLGIL YIATPNKASQ GSTLVHPFRA LGKNSELLVV SAREDVATWQ 
QSSLSLRWAS RLRAPTSTEA NHIRLSCLAV GLALLKRCVL MYGSLPSFHA IMGPLQALLT 
DHLADCSHPQ ELQELCQSTL TEMESQKQLC RPLTCEKSKP VPLKLFTPRL VKVLEFGRKQ 
GSSKEEQERK RLIHKHKREF KGAVREIRKD NQFLARMQLS EIMERDAERK RKVKQLFNSL 
ATQEGEWKAL KRKKFKK

Genular Protein ID: 4009680238

Symbol: A8KA74_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8KA74

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 3 SAM 1

Sequence Information:

  • Length: 857
  • Mass: 97670
  • Checksum: 440812675040B532
  • Sequence:
    • MAKAKKVGAR RKASGAPAGA RGGPAKANSN PFEVKVNRQK FQILGRKTRH DVGLPGVSRA 
RALRKRTQTL LKEYKERDKS NVFRDKRFGE YNSNMSPEEK MMKRFALEQQ RHHEKKSIYN 
LNEDEELTHY GQSLADIEKH NDIVDSDSDA EDRGTLSAEL TAAHFGGGGG LLHKKTQQEG 
EEREKPKSRK ELIEELIAKS KQEKRERQAQ REDALELTEK LDQDWKEIQT LLSHKTPKSE 
NRDKKEKPKP DAYDMMVREL GFEMKAQPSN RMKTEAELAK EEQEHLRKLE AERLRRMLGK 
DEDENVKKPK HMSADDLNDG FVLDKDDRRL LSYKDGKMNV EEDVQEEQSK EASDPESNEE 
EGDSSGGEDT EESDSPDSHS DLESNVESEE ENEKPAKEQR QTPGKGLISG KERAGKATRD 
ELPYTFAAPE SYEELRSLLL GRSMEEQLLV VERIQKCNHP SLAEGNKAKL EKLFGFLLEY 
VGDLATDDPP DLTVIDKLVV HLYHLCQMFP ESASDAIKFV LRDAMHEMEE MIETKGRAAL 
PGLDVLIYLK ITGLLFPTSD FWHPVVTPAL VCLSQLLTKC PILSLQDVVK GLFVCCLFLE 
YVALSQRFIP ELINFLLGIL YIATPNKASQ GSTLVHPFRA LGKNSELLVV SAREDVATWQ 
QSSLSLRWAS RLRAPTSTEA NHIRLSCLAV GLALLKRCVL MYGSLPSFHA IMGPLRALLT 
DHLADCSHPQ ELQELCQSTL TEMESQKQLC RPLTCEKSKP VPLKLFTPRL VKVLEFGRKQ 
GSSKEEQERK RLIHKHKREF KGAVREIRKD NQFLARMQLS EIMERDAERK RKVKQLFNSL 
ATQEGEWKAL KRKKFKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.