Details for: PEA15

Gene ID: 8682

Symbol: PEA15

Ensembl ID: ENSG00000162734

Description: proliferation and apoptosis adaptor protein 15

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 346.6516
    Cell Significance Index: -53.9200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 209.6644
    Cell Significance Index: -53.1800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 131.5701
    Cell Significance Index: -54.2000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 107.8533
    Cell Significance Index: -50.9200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 100.5767
    Cell Significance Index: -40.8600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 91.3906
    Cell Significance Index: -47.0100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 43.8986
    Cell Significance Index: -54.1300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 42.9121
    Cell Significance Index: -40.9700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.7725
    Cell Significance Index: -47.6100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.7859
    Cell Significance Index: -54.4000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.9715
    Cell Significance Index: -36.7700
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 8.8170
    Cell Significance Index: 67.9600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 3.4432
    Cell Significance Index: 180.7800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.9739
    Cell Significance Index: 85.2500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.5397
    Cell Significance Index: 160.0700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.1478
    Cell Significance Index: 37.9600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.1083
    Cell Significance Index: 109.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.5535
    Cell Significance Index: 115.7800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1867
    Cell Significance Index: 238.0500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.9930
    Cell Significance Index: 115.7200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8197
    Cell Significance Index: 38.5300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.8111
    Cell Significance Index: 104.7900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.7232
    Cell Significance Index: 48.6300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.5908
    Cell Significance Index: 16.0800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5531
    Cell Significance Index: 499.3800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5359
    Cell Significance Index: 68.7000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5232
    Cell Significance Index: 64.3400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5119
    Cell Significance Index: 26.5900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4856
    Cell Significance Index: 174.1700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.4810
    Cell Significance Index: 56.7200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3873
    Cell Significance Index: 63.0000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3567
    Cell Significance Index: 64.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3095
    Cell Significance Index: 14.4300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2912
    Cell Significance Index: 39.9900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2806
    Cell Significance Index: 27.7600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2268
    Cell Significance Index: 24.6700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2076
    Cell Significance Index: 113.3600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1335
    Cell Significance Index: 59.0300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1181
    Cell Significance Index: 7.2600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1008
    Cell Significance Index: 19.1900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0757
    Cell Significance Index: 2.1800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0603
    Cell Significance Index: 11.9700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0226
    Cell Significance Index: 0.4900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0069
    Cell Significance Index: -9.3900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0108
    Cell Significance Index: -0.2700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0130
    Cell Significance Index: -0.7800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0138
    Cell Significance Index: -21.2300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0164
    Cell Significance Index: -10.2700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0167
    Cell Significance Index: -31.4000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0182
    Cell Significance Index: -13.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0187
    Cell Significance Index: -3.2000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0197
    Cell Significance Index: -36.3600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0329
    Cell Significance Index: -24.9300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0344
    Cell Significance Index: -3.5200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0425
    Cell Significance Index: -29.3700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0458
    Cell Significance Index: -25.8400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0461
    Cell Significance Index: -1.2300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0490
    Cell Significance Index: -35.9100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0585
    Cell Significance Index: -37.1500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0611
    Cell Significance Index: -7.0100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0930
    Cell Significance Index: -42.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1048
    Cell Significance Index: -4.7500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1085
    Cell Significance Index: -1.8600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1189
    Cell Significance Index: -8.2300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1284
    Cell Significance Index: -27.0400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1350
    Cell Significance Index: -38.8400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1980
    Cell Significance Index: -14.0000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2066
    Cell Significance Index: -23.5800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2164
    Cell Significance Index: -2.5800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2339
    Cell Significance Index: -8.2200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2757
    Cell Significance Index: -15.4700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2775
    Cell Significance Index: -40.3400
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.3312
    Cell Significance Index: -2.0800
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.3496
    Cell Significance Index: -3.0800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3709
    Cell Significance Index: -5.0600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3904
    Cell Significance Index: -10.2700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4374
    Cell Significance Index: -7.3200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4579
    Cell Significance Index: -35.1400
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.4688
    Cell Significance Index: -2.8900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.4707
    Cell Significance Index: -8.7000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4724
    Cell Significance Index: -30.4800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4949
    Cell Significance Index: -30.3400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5205
    Cell Significance Index: -54.1900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5241
    Cell Significance Index: -10.9700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5350
    Cell Significance Index: -14.3400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5382
    Cell Significance Index: -42.6300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.5810
    Cell Significance Index: -3.5100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.5942
    Cell Significance Index: -6.7500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.6181
    Cell Significance Index: -17.6400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.6323
    Cell Significance Index: -17.6700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.6962
    Cell Significance Index: -15.2500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7403
    Cell Significance Index: -23.7100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.7582
    Cell Significance Index: -18.1800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.8377
    Cell Significance Index: -17.8400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.8774
    Cell Significance Index: -30.4900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.9123
    Cell Significance Index: -33.4900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.9499
    Cell Significance Index: -27.9800
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -1.0137
    Cell Significance Index: -7.2800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.0576
    Cell Significance Index: -46.7800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.0794
    Cell Significance Index: -31.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PEA15 is a phosphoprotein that belongs to the 14-3-3 family of proteins. It is highly expressed in various cell types, including respiratory basal cells, glycinergic neurons, and fibroblasts from mammary gland and prostate tissue. PEA15 is characterized by its ability to interact with multiple signaling pathways, including MAPK, PI3K, and NF-κB pathways. Its unique structure and function enable it to modulate the activity of various proteins, including kinases, phosphatases, and transcription factors. **Pathways and Functions:** PEA15 is involved in multiple signaling pathways that regulate cell survival, proliferation, and apoptosis. Some of its key functions and pathways include: 1. **Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors**: PEA15 interacts with death domain receptors, such as Fas and TNF-α receptors, to inhibit the activation of caspases and prevent apoptosis. 2. **Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors**: PEA15 can also enhance the activation of caspases, promoting apoptosis in certain cell types. 3. **MAPK cascade regulation**: PEA15 interacts with MAPK kinases, such as JNK and p38, to modulate the activity of these kinases and influence cell survival and proliferation. 4. **Negative regulation of glucose import**: PEA15 can inhibit the activity of glucose transporters, such as GLUT1, to regulate glucose metabolism in cells. 5. **Raf-independent MAPK1/3 activation**: PEA15 can activate MAPK1 and MAPK3 independently of Raf, a key kinase in the MAPK pathway. **Clinical Significance:** PEA15 has been implicated in various diseases and disorders, including cancer, neurodegenerative diseases, and metabolic disorders. Its dysregulation has been linked to: 1. **Cancer**: PEA15 is overexpressed in various types of cancer, including breast, prostate, and lung cancer, and is associated with poor prognosis. 2. **Neurodegenerative diseases**: PEA15 has been implicated in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, where it may play a role in regulating cell survival and apoptosis. 3. **Metabolic disorders**: PEA15 has been linked to metabolic disorders, such as diabetes and obesity, where it may regulate glucose metabolism and insulin signaling. In conclusion, PEA15 is a multifunctional adaptor protein that plays a critical role in regulating cell survival, proliferation, and apoptosis. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of further research into the molecular mechanisms of PEA15 and its potential therapeutic applications.

Genular Protein ID: 3240840422

Symbol: PEA15_HUMAN

Name: Astrocytic phosphoprotein PEA-15

UniProtKB Accession Codes:

Q15121 B1AKZ3 O00511

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8662970

Title: The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human.

PubMed ID: 8662970

DOI: 10.1074/jbc.271.25.14800

PubMed ID: 9670003

Title: PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus.

PubMed ID: 9670003

DOI: 10.1093/emboj/17.14.3858

PubMed ID: 10607908

Title: Molecular characterization of the human PEA15 gene on 1q21-q22 and association with type 2 diabetes mellitus in Pima Indians.

PubMed ID: 10607908

DOI: 10.1016/s0378-1119(99)00455-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10442631

Title: PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis.

PubMed ID: 10442631

DOI: 10.1038/sj.onc.1202831

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 130
  • Mass: 15040
  • Checksum: 8D0F93A40B299FB2
  • Sequence:
    • MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL 
SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI 
IKLAPPPKKA

Genular Protein ID: 3282828145

Symbol: B1AKZ5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B1AKZ5

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 108
  • Mass: 12530
  • Checksum: 49F0527AE97FE9B5
  • Sequence:
    • MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKNNLSY IEHIFEISRR PDLLTMVVDY 
RTRVLKISEE DELDTKLTRI PSAKKYKDII RQPSEEEIIK LAPPPKKA

Genular Protein ID: 1005714896

Symbol: Q96FS5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96FS5

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 RefSeq 4

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 74
  • Mass: 8437
  • Checksum: 1BA1A8D70B3A12A2
  • Sequence:
    • MYIKTALPCL PFFVVSSINL LSRPERGWEG NATVKGVAES NCYIVQTKKK AFSKNIKFTC 
SLRDYLDKVQ VRSF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.