Details for: RNMT
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 408.2414
Cell Significance Index: -63.5000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 236.3949
Cell Significance Index: -59.9600 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 154.7648
Cell Significance Index: -63.7600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 151.5708
Cell Significance Index: -71.5600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 142.4713
Cell Significance Index: -57.8800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 127.8225
Cell Significance Index: -65.7500 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 106.7476
Cell Significance Index: -71.6300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 61.2364
Cell Significance Index: -58.4700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 55.7846
Cell Significance Index: -68.7800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 25.0106
Cell Significance Index: -67.0000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 17.8584
Cell Significance Index: -70.4700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 16.0543
Cell Significance Index: -49.3100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 13.3282
Cell Significance Index: -29.1700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 3.2904
Cell Significance Index: 535.1500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 3.1719
Cell Significance Index: 219.3600 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 2.8425
Cell Significance Index: 21.9100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.8538
Cell Significance Index: 49.5000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.7312
Cell Significance Index: 23.6200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.7156
Cell Significance Index: 49.1800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.5208
Cell Significance Index: 79.8500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.4399
Cell Significance Index: 75.0000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.3412
Cell Significance Index: 241.7800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.2348
Cell Significance Index: 245.0500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.2262
Cell Significance Index: 1107.1800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.2071
Cell Significance Index: 148.4200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.1966
Cell Significance Index: 164.3300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.1856
Cell Significance Index: 72.8700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.1262
Cell Significance Index: 72.6600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.0797
Cell Significance Index: 589.6300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9387
Cell Significance Index: 336.6800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.9235
Cell Significance Index: 408.3200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.9209
Cell Significance Index: 70.6700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.8719
Cell Significance Index: 40.9800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.6356
Cell Significance Index: 29.6400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6158
Cell Significance Index: 60.9200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.6112
Cell Significance Index: 34.3000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.5697
Cell Significance Index: 40.2900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5092
Cell Significance Index: 352.1500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.4698
Cell Significance Index: 60.2300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4676
Cell Significance Index: 24.2900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.4611
Cell Significance Index: 12.5500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4569
Cell Significance Index: 13.1700 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.4475
Cell Significance Index: 5.5500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4218
Cell Significance Index: 19.1200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3987
Cell Significance Index: 750.6700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.3941
Cell Significance Index: 606.7300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3763
Cell Significance Index: 23.7200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2986
Cell Significance Index: 35.2100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2573
Cell Significance Index: 6.1700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2184
Cell Significance Index: 402.8500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2156
Cell Significance Index: 43.2500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.2056
Cell Significance Index: 279.5600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1720
Cell Significance Index: 109.2300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1605
Cell Significance Index: 20.7300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1505
Cell Significance Index: 68.3100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0945
Cell Significance Index: 17.9800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0865
Cell Significance Index: 6.4500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0501
Cell Significance Index: 8.5600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.0154
Cell Significance Index: 0.6800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0068
Cell Significance Index: 0.1900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0328
Cell Significance Index: -24.0500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0332
Cell Significance Index: -24.5800 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0426
Cell Significance Index: -1.1200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0444
Cell Significance Index: -33.6300 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0482
Cell Significance Index: -0.9400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0495
Cell Significance Index: -27.9000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0796
Cell Significance Index: -49.7300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0852
Cell Significance Index: -3.2300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1154
Cell Significance Index: -11.7900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1249
Cell Significance Index: -4.3900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1266
Cell Significance Index: -8.5100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1531
Cell Significance Index: -2.2600 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.1830
Cell Significance Index: -1.6900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1849
Cell Significance Index: -3.8700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2046
Cell Significance Index: -43.0900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2089
Cell Significance Index: -30.3700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2104
Cell Significance Index: -60.5300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2124
Cell Significance Index: -3.6400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2925
Cell Significance Index: -6.2300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3273
Cell Significance Index: -37.5000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3454
Cell Significance Index: -5.7800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3853
Cell Significance Index: -40.1200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3959
Cell Significance Index: -46.1400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.5088
Cell Significance Index: -17.6800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5257
Cell Significance Index: -60.0100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.5961
Cell Significance Index: -14.9000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.6349
Cell Significance Index: -69.0600 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.6573
Cell Significance Index: -7.8400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7165
Cell Significance Index: -56.7500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.8420
Cell Significance Index: -51.6200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.8507
Cell Significance Index: -22.7600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.8981
Cell Significance Index: -25.6300 - Cell Name: peg cell (CL4033014)
Fold Change: -0.9137
Cell Significance Index: -21.1100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.9364
Cell Significance Index: -29.9900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.9459
Cell Significance Index: -23.0800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -1.0069
Cell Significance Index: -18.6100 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -1.0191
Cell Significance Index: -8.3100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.1356
Cell Significance Index: -29.1900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -1.1979
Cell Significance Index: -35.1800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.2735
Cell Significance Index: -27.5900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1021970630
Symbol: MCES_HUMAN
Name: mRNA cap guanine-N7 methyltransferase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9790902
Title: Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)methyltransferase, an mRNA cap methylase.
PubMed ID: 9790902
PubMed ID: 9705270
Title: Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes.
PubMed ID: 9705270
PubMed ID: 10589710
Title: The Candida albicans gene for mRNA 5'-cap methyltransferase: identification of the additional residues essential for catalysis.
PubMed ID: 10589710
PubMed ID: 9455477
Title: Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 9455477
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10347220
Title: Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes.
PubMed ID: 10347220
PubMed ID: 11114884
Title: Cap methyltransferase selective binding and methylation of GpppG-RNA are stimulated by importin-alpha.
PubMed ID: 11114884
DOI: 10.1101/gad.848200
PubMed ID: 15767670
Title: Human mRNA cap methyltransferase: alternative nuclear localization signal motifs ensure nuclear localization required for viability.
PubMed ID: 15767670
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22099306
Title: RAM/Fam103a1 is required for mRNA cap methylation.
PubMed ID: 22099306
PubMed ID: 27422871
Title: Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.
PubMed ID: 27422871
DOI: 10.1093/nar/gkw637
Sequence Information:
- Length: 476
- Mass: 54844
- Checksum: EC919BC41BD5E2B3
- Sequence:
MANSAKAEEY EKMSLEQAKA SVNSETESSF NINENTTASG TGLSEKTSVC RQVDIARKRK EFEDDLVKES SSCGKDTPSK KRKLDPEIVP EEKDCGDAEG NSKKRKRETE DVPKDKSSTG DGTQNKRKIA LEDVPEKQKN LEEGHSSTVA AHYNELQEVG LEKRSQSRIF YLRNFNNWMK SVLIGEFLEK VRQKKKRDIT VLDLGCGKGG DLLKWKKGRI NKLVCTDIAD VSVKQCQQRY EDMKNRRDSE YIFSAEFITA DSSKELLIDK FRDPQMCFDI CSCQFVCHYS FESYEQADMM LRNACERLSP GGYFIGTTPN SFELIRRLEA SETESFGNEI YTVKFQKKGD YPLFGCKYDF NLEGVVDVPE FLVYFPLLNE MAKKYNMKLV YKKTFLEFYE EKIKNNENKM LLKRMQALEP YPANESSKLV SEKVDDYEHA AKYMKNSQVR LPLGTLSKSE WEATSIYLVF AFEKQQ
Genular Protein ID: 2188507789
Symbol: A8K946_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 504
- Mass: 57751
- Checksum: 9AD0806CAA3F124D
- Sequence:
MANSAKAEEY EKMSLEQAKP SVNSETESSF NINENTTASG TGLSEKTSVC RQVDIARKRK EFEDDLVKES SSCGKDTPSK KRKLDPEIVP EEKDCGDAEG NSKKRKRETE DVPKDKSSTG DGTQNKRKIA LEDVPEKQKN LEEGHSSTVA AHYNELQEVG LEKRSQSRIF YLRNFNNWMK SVLIGEFLEK VRQKKKRDIT VLDLGCGKGG DLLKWKKGRI NKLVCTDIAD VSVKQCQQRY EDMKNRRDSE YIFSAEFITA DSSKELLIDK FRDPQMCFDI CSCQFVCHYS FESYEQADMM LRNACERLSP GGYFIGTTPN SFELIRRLEA SETESFGNEI YTVKFQKKGD YPLFGCKYDF NLEGVVDVPE FLVYFPLLNE MAKKYNMKLV YKKTFLEFYE EKIKNNENKM LLKRMQALEP YPANESSKLV SEKVDDYEHA AKYMKNSQVR LPLGTLSKSE WEATRLTVTI MREAWLSTVG PGRAPVAASS VKWGTPRPAM QFIL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.