Details for: CRADD
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 244.9448
Cell Significance Index: -38.1000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 157.1103
Cell Significance Index: -39.8500 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 100.3526
Cell Significance Index: -41.3400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 76.7987
Cell Significance Index: -31.2000 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 57.7030
Cell Significance Index: -38.7200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 32.9209
Cell Significance Index: -40.5900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 15.6996
Cell Significance Index: -34.3600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.4605
Cell Significance Index: -33.3800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 11.9976
Cell Significance Index: -36.8500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 10.5295
Cell Significance Index: -41.5500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 7.9024
Cell Significance Index: 1148.7000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 4.3811
Cell Significance Index: 336.2000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 3.0419
Cell Significance Index: 78.1900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.7456
Cell Significance Index: 154.0700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.6024
Cell Significance Index: 516.4500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.5600
Cell Significance Index: 54.7200 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 2.2877
Cell Significance Index: 31.9900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.1649
Cell Significance Index: 58.0100 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 2.0599
Cell Significance Index: 50.2600 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.7593
Cell Significance Index: 28.2300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.5314
Cell Significance Index: 549.2900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.4650
Cell Significance Index: 64.8000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.4537
Cell Significance Index: 291.6200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.4308
Cell Significance Index: 54.1800 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.4054
Cell Significance Index: 27.4300 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.2703
Cell Significance Index: 18.2700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.1624
Cell Significance Index: 78.1600 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 1.1439
Cell Significance Index: 11.5400 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.0708
Cell Significance Index: 9.5100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.9733
Cell Significance Index: 27.2000 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.9458
Cell Significance Index: 5.8400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.9285
Cell Significance Index: 15.6400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7724
Cell Significance Index: 697.4000 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 0.7617
Cell Significance Index: 12.2900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.6930
Cell Significance Index: 16.6200 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.6776
Cell Significance Index: 8.4100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.6446
Cell Significance Index: 409.4000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.6191
Cell Significance Index: 37.1700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.5823
Cell Significance Index: 1096.4900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5364
Cell Significance Index: 58.3500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.5198
Cell Significance Index: 31.9500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4509
Cell Significance Index: 73.3400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4498
Cell Significance Index: 44.5000 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.4482
Cell Significance Index: 6.3000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.4300
Cell Significance Index: 12.2700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.3940
Cell Significance Index: 606.5300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.3910
Cell Significance Index: 177.4400 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 0.3002
Cell Significance Index: 3.7800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2773
Cell Significance Index: 7.9900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2727
Cell Significance Index: 17.1900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.2573
Cell Significance Index: 29.9900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2414
Cell Significance Index: 445.1700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2328
Cell Significance Index: 3.9900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2315
Cell Significance Index: 5.0200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2264
Cell Significance Index: 15.6600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1883
Cell Significance Index: 35.8400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1660
Cell Significance Index: 225.7400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.1451
Cell Significance Index: 1.7300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1354
Cell Significance Index: 8.7400 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.1314
Cell Significance Index: 1.9400 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.1121
Cell Significance Index: 1.6100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0939
Cell Significance Index: 16.9400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0772
Cell Significance Index: 3.5000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0714
Cell Significance Index: 8.7800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0680
Cell Significance Index: 42.4500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0618
Cell Significance Index: 3.2100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0120
Cell Significance Index: 6.5700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0018
Cell Significance Index: 0.3000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0138
Cell Significance Index: -6.0900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0148
Cell Significance Index: -11.0000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0326
Cell Significance Index: -18.4000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0383
Cell Significance Index: -28.1100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0425
Cell Significance Index: -32.1800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0506
Cell Significance Index: -1.3500 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: -0.0599
Cell Significance Index: -0.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0641
Cell Significance Index: -6.6800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0780
Cell Significance Index: -10.7100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1056
Cell Significance Index: -22.2500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1167
Cell Significance Index: -33.5900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1205
Cell Significance Index: -13.8100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1255
Cell Significance Index: -12.8200 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.1315
Cell Significance Index: -1.6400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1329
Cell Significance Index: -4.6700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1373
Cell Significance Index: -6.4000 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.1594
Cell Significance Index: -1.3000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1612
Cell Significance Index: -2.3800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1871
Cell Significance Index: -23.9900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1906
Cell Significance Index: -24.6300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1983
Cell Significance Index: -23.3900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2045
Cell Significance Index: -6.5500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2568
Cell Significance Index: -19.1400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2985
Cell Significance Index: -15.6800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3119
Cell Significance Index: -14.6600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3133
Cell Significance Index: -6.6500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3292
Cell Significance Index: -37.5800 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.3336
Cell Significance Index: -4.2100 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.3476
Cell Significance Index: -6.0100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.4121
Cell Significance Index: -2.4900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4157
Cell Significance Index: -32.9200 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.4299
Cell Significance Index: -6.5400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 281098821
Symbol: CRADD_HUMAN
Name: Death domain-containing protein CRADD
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9044836
Title: CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP.
PubMed ID: 9044836
PubMed ID: 8985253
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15073321
Title: The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress.
PubMed ID: 15073321
PubMed ID: 16652156
Title: Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage.
PubMed ID: 16652156
PubMed ID: 9695946
Title: Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment.
PubMed ID: 9695946
PubMed ID: 17159900
Title: Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway.
PubMed ID: 17159900
PubMed ID: 17289572
Title: Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
PubMed ID: 17289572
PubMed ID: 22279524
Title: Genetic mapping and exome sequencing identify variants associated with five novel diseases.
PubMed ID: 22279524
Sequence Information:
- Length: 199
- Mass: 22745
- Checksum: 3437CC612C85E402
- Sequence:
MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE
Genular Protein ID: 4103484518
Symbol: Q8IY43_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 199
- Mass: 22732
- Checksum: 73AE79B1BA066756
- Sequence:
MEARDKQVLR SLRLELGAEV LVEGLVLQYV YEEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE
Genular Protein ID: 1239319037
Symbol: F8VVY5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
Sequence Information:
- Length: 130
- Mass: 14759
- Checksum: FDC5ABE77609ABCA
- Sequence:
MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG LEEKGRTGRR MGWGAGEEKG QKCQTVGMRT
Genular Protein ID: 561311829
Symbol: B4DJT6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 121
- Mass: 13958
- Checksum: A1433D9285A1634D
- Sequence:
MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGVLTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTGLPAE MRKLRPKDSV TCLASQLTWR F
Genular Protein ID: 2498899220
Symbol: F5H7C2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
Sequence Information:
- Length: 121
- Mass: 14030
- Checksum: 5FB1E2BF6AA17537
- Sequence:
MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAE MRKLRPKDSV TCLASQLTWR F
Genular Protein ID: 1486343851
Symbol: F8VV49_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
Sequence Information:
- Length: 115
- Mass: 13168
- Checksum: 4700DF296A775C9B
- Sequence:
MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAV AIIRLPRELS LPTLL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.