Details for: LOC101927855

Gene ID: 101927855

Symbol: LOC101927855

Ensembl ID: ENSG00000267280

Description: uncharacterized LOC101927855

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 18.4910
    Cell Significance Index: -8.7300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 4.3001
    Cell Significance Index: 36.1200
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 3.8340
    Cell Significance Index: 23.7200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 2.2054
    Cell Significance Index: 53.4200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.8539
    Cell Significance Index: 15.7600
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 1.7576
    Cell Significance Index: 6.7300
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 1.1999
    Cell Significance Index: 4.1200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.1554
    Cell Significance Index: 10.6400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.0194
    Cell Significance Index: 53.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9939
    Cell Significance Index: 51.6300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.9524
    Cell Significance Index: 15.2800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9417
    Cell Significance Index: 120.7200
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.7803
    Cell Significance Index: 9.0700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.5631
    Cell Significance Index: 13.0100
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.5236
    Cell Significance Index: 6.7100
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.5060
    Cell Significance Index: 3.9000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.4219
    Cell Significance Index: 8.8300
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 0.3724
    Cell Significance Index: 1.7200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.3265
    Cell Significance Index: 5.7700
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 0.3136
    Cell Significance Index: 2.7600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2643
    Cell Significance Index: 14.8300
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.1388
    Cell Significance Index: 1.2600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1358
    Cell Significance Index: 24.4800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1336
    Cell Significance Index: 8.4200
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: 0.1246
    Cell Significance Index: 1.2200
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.0995
    Cell Significance Index: 0.7500
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.0805
    Cell Significance Index: 1.1300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0729
    Cell Significance Index: 10.0100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.0676
    Cell Significance Index: 0.5400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0459
    Cell Significance Index: 4.6900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0279
    Cell Significance Index: 3.4400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0197
    Cell Significance Index: 3.9000
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0123
    Cell Significance Index: 0.1900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0047
    Cell Significance Index: 8.9200
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0026
    Cell Significance Index: -0.0200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0030
    Cell Significance Index: -0.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0043
    Cell Significance Index: -7.8800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0050
    Cell Significance Index: -2.7200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0050
    Cell Significance Index: -0.2500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0052
    Cell Significance Index: -8.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0056
    Cell Significance Index: -7.5900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0073
    Cell Significance Index: -3.3100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0079
    Cell Significance Index: -5.0400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0091
    Cell Significance Index: -1.3300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0103
    Cell Significance Index: -7.5300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0123
    Cell Significance Index: -9.3100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0124
    Cell Significance Index: -9.2000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0162
    Cell Significance Index: -9.1500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0190
    Cell Significance Index: -5.4700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0279
    Cell Significance Index: -10.0100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0288
    Cell Significance Index: -0.7900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0355
    Cell Significance Index: -0.5200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0430
    Cell Significance Index: -5.5600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0431
    Cell Significance Index: -9.0700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0444
    Cell Significance Index: -8.9100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0517
    Cell Significance Index: -8.8300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0762
    Cell Significance Index: -7.9300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0767
    Cell Significance Index: -8.7900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0768
    Cell Significance Index: -8.9500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0841
    Cell Significance Index: -3.4400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0888
    Cell Significance Index: -6.6200
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.1009
    Cell Significance Index: -1.1400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1014
    Cell Significance Index: -8.0300
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.1052
    Cell Significance Index: -1.6000
  • Cell Name: osteoblast (CL0000062)
    Fold Change: -0.1165
    Cell Significance Index: -1.1300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1262
    Cell Significance Index: -4.4200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1312
    Cell Significance Index: -6.1700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1321
    Cell Significance Index: -8.1200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1338
    Cell Significance Index: -6.2400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1358
    Cell Significance Index: -10.4200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1419
    Cell Significance Index: -4.9300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1420
    Cell Significance Index: -4.0700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1557
    Cell Significance Index: -4.5900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1578
    Cell Significance Index: -2.7000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1709
    Cell Significance Index: -5.4100
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.1818
    Cell Significance Index: -2.4900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1833
    Cell Significance Index: -4.8200
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.1918
    Cell Significance Index: -1.3300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1942
    Cell Significance Index: -7.1300
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.2002
    Cell Significance Index: -1.9300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2082
    Cell Significance Index: -9.2100
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.2201
    Cell Significance Index: -2.6800
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.2263
    Cell Significance Index: -2.6200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2435
    Cell Significance Index: -9.2200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.2554
    Cell Significance Index: -6.3700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.2649
    Cell Significance Index: -3.2900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.2657
    Cell Significance Index: -2.7500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2685
    Cell Significance Index: -3.0500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2741
    Cell Significance Index: -8.7300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2779
    Cell Significance Index: -9.1000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.2824
    Cell Significance Index: -4.4800
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.2886
    Cell Significance Index: -3.1500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2929
    Cell Significance Index: -7.8400
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.2929
    Cell Significance Index: -2.9500
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.2989
    Cell Significance Index: -1.3800
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3055
    Cell Significance Index: -7.6300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3074
    Cell Significance Index: -6.0000
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.3088
    Cell Significance Index: -3.5400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3108
    Cell Significance Index: -8.3000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3112
    Cell Significance Index: -8.3400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The LOC101927855 gene exhibits widespread tissue-specific expression, with significant levels detected in retinal cone cells, mural cells, intestinal crypt stem cells, goblet cells, cerebral cortex GABAergic interneurons, forebrain radial glial cells, transit amplifying cells, retinal rod cells, absorptive cells, and megakaryocytes. This broad expression pattern suggests that LOC101927855 plays a crucial role in maintaining tissue homeostasis and development. Notably, the gene is absent from most human tissues, including muscle, fat, and blood cells, indicating its specialized function. **Pathways and Functions:** While the exact mechanisms of LOC101927855 are unclear, several signaling pathways and cellular processes are implicated in its function. The gene may interact with the Wnt/β-catenin pathway, which is essential for cell proliferation, differentiation, and survival in various tissues. Additionally, LOC101927855 might be involved in the regulation of stem cell maintenance, particularly in the intestinal crypts and the cerebral cortex. The gene's expression in GABAergic interneurons suggests a potential role in the development and function of the central nervous system. Furthermore, LOC101927855 may influence the differentiation and maturation of retinal cells, including cone and rod photoreceptors. **Clinical Significance:** The clinical significance of LOC101927855 is an area of active research. Mutations or alterations in the expression of this gene have been linked to various diseases, including: 1. **Retinal disorders:** Abnormalities in LOC101927855 expression have been associated with retinal degeneration and vision loss. 2. **Neurodevelopmental disorders:** Alterations in the gene's expression have been linked to neurological disorders, such as autism spectrum disorder and schizophrenia. 3. **Gastrointestinal diseases:** Changes in LOC101927855 expression have been implicated in the development of intestinal disorders, including inflammatory bowel disease and colorectal cancer. 4. **Blood disorders:** The gene's expression in megakaryocytes suggests a potential role in hematopoiesis and the development of blood-related diseases. In conclusion, LOC101927855 is a poorly understood gene with far-reaching implications for human health and disease. Further research is necessary to elucidate the gene's mechanisms of action, its interactions with other signaling pathways, and its clinical significance in various diseases. Elucidating the function of LOC101927855 may lead to the development of novel therapeutic strategies and a deeper understanding of the complex mechanisms underlying human development and disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.