Details for: ADARB1

Gene ID: 104

Symbol: ADARB1

Ensembl ID: ENSG00000197381

Description: adenosine deaminase RNA specific B1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 167.6040
    Cell Significance Index: -26.0700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 100.9291
    Cell Significance Index: -25.6000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 52.5283
    Cell Significance Index: -21.3400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 22.3516
    Cell Significance Index: -21.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.2497
    Cell Significance Index: -26.2000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.5899
    Cell Significance Index: -25.6900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.1018
    Cell Significance Index: -19.9200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.6776
    Cell Significance Index: -26.3500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.3130
    Cell Significance Index: -19.3900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 6.2774
    Cell Significance Index: 77.8600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.4379
    Cell Significance Index: 249.0300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.1489
    Cell Significance Index: 68.9500
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 2.4858
    Cell Significance Index: 19.1600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.9958
    Cell Significance Index: 28.7100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.9763
    Cell Significance Index: 396.4500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.9533
    Cell Significance Index: 131.3400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.5534
    Cell Significance Index: 68.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.5486
    Cell Significance Index: 58.6400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.1536
    Cell Significance Index: 413.7700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9481
    Cell Significance Index: 24.3700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9422
    Cell Significance Index: 651.6500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.8981
    Cell Significance Index: 15.3900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8449
    Cell Significance Index: 167.6800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.7247
    Cell Significance Index: 55.6100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.6385
    Cell Significance Index: 18.2200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.5079
    Cell Significance Index: 73.8300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4317
    Cell Significance Index: 82.1600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.4189
    Cell Significance Index: 10.2200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.3430
    Cell Significance Index: 528.0400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3189
    Cell Significance Index: 19.6000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.3088
    Cell Significance Index: 6.6000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2302
    Cell Significance Index: 22.7800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.2268
    Cell Significance Index: 5.4400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2035
    Cell Significance Index: 183.7800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1870
    Cell Significance Index: 3.6500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1618
    Cell Significance Index: 71.5400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1410
    Cell Significance Index: 3.9400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1357
    Cell Significance Index: 86.1800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1174
    Cell Significance Index: 19.0900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1040
    Cell Significance Index: 5.4600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0685
    Cell Significance Index: 12.3500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0664
    Cell Significance Index: 122.3800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0634
    Cell Significance Index: 34.6300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0456
    Cell Significance Index: 85.9300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0362
    Cell Significance Index: 49.2700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0320
    Cell Significance Index: 3.9400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0320
    Cell Significance Index: 14.5300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0181
    Cell Significance Index: 1.1400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0137
    Cell Significance Index: 1.4900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0059
    Cell Significance Index: 0.0700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0007
    Cell Significance Index: -0.0200
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0085
    Cell Significance Index: -0.0700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0209
    Cell Significance Index: -0.2600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0231
    Cell Significance Index: -1.4200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0280
    Cell Significance Index: -3.8400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0282
    Cell Significance Index: -20.6800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0341
    Cell Significance Index: -25.2900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0355
    Cell Significance Index: -26.8700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0454
    Cell Significance Index: -28.3300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0460
    Cell Significance Index: -25.9400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0701
    Cell Significance Index: -8.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0711
    Cell Significance Index: -2.5000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0720
    Cell Significance Index: -1.8000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0749
    Cell Significance Index: -9.6000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0787
    Cell Significance Index: -22.6500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1034
    Cell Significance Index: -17.6600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1122
    Cell Significance Index: -13.0700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1141
    Cell Significance Index: -5.1700
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.1185
    Cell Significance Index: -1.6700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1258
    Cell Significance Index: -0.7600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1278
    Cell Significance Index: -26.9200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1282
    Cell Significance Index: -7.7000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.1373
    Cell Significance Index: -0.9300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.1417
    Cell Significance Index: -1.8900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1500
    Cell Significance Index: -10.3800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1519
    Cell Significance Index: -2.1800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1691
    Cell Significance Index: -21.8500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1717
    Cell Significance Index: -3.7200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1809
    Cell Significance Index: -2.6700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1846
    Cell Significance Index: -18.8600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1947
    Cell Significance Index: -9.1500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1954
    Cell Significance Index: -20.3500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2008
    Cell Significance Index: -23.0000
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.2035
    Cell Significance Index: -2.1200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2095
    Cell Significance Index: -14.8200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2196
    Cell Significance Index: -4.6600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2214
    Cell Significance Index: -7.0900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2312
    Cell Significance Index: -12.0100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2349
    Cell Significance Index: -2.9700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2367
    Cell Significance Index: -12.3300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2575
    Cell Significance Index: -7.4200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2624
    Cell Significance Index: -19.5600
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: -0.2831
    Cell Significance Index: -2.9300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2971
    Cell Significance Index: -13.8500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2977
    Cell Significance Index: -23.5800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2987
    Cell Significance Index: -19.2700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3005
    Cell Significance Index: -9.5700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3103
    Cell Significance Index: -6.2300
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.3151
    Cell Significance Index: -3.8200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3170
    Cell Significance Index: -10.3800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **RNA Editing Function:** ADARB1 catalyzes the conversion of adenosine to inosine in dsRNA, a process essential for regulating gene expression, viral replication, and immune response. 2. **Immune Response:** ADARB1 plays a critical role in the innate immune response, particularly in the defense against viral infections. 3. **Cellular Expression:** ADARB1 is expressed in various cell types, including neurons, immune cells, and epithelial cells, suggesting its involvement in multiple physiological processes. 4. **Pathway Involvement:** ADARB1 is involved in several cellular pathways, including adenosine to inosine editing, base conversion or substitution editing, C6 deamination of adenosine, and regulation of cell cycle. **Pathways and Functions:** 1. **Adenosine to Inosine Editing:** ADARB1 catalyzes the conversion of adenosine to inosine in dsRNA, which regulates gene expression, viral replication, and immune response. 2. **Base Conversion or Substitution Editing:** ADARB1 is involved in base conversion or substitution editing, which is essential for the regulation of gene expression and immune response. 3. **C6 Deamination of Adenosine:** ADARB1 participates in the C6 deamination of adenosine, which is involved in the regulation of gene expression and immune response. 4. **Regulation of Cell Cycle:** ADARB1 regulates the cell cycle by modulating the expression of genes involved in cell proliferation and differentiation. 5. **Immune Response:** ADARB1 plays a critical role in the innate immune response, particularly in the defense against viral infections. **Clinical Significance:** Dysregulation of ADARB1 has been implicated in various diseases, including: 1. **Viral Infections:** ADARB1 plays a critical role in the defense against viral infections, and dysregulation of ADARB1 can lead to increased susceptibility to viral infections. 2. **Neurological Disorders:** ADARB1 is expressed in neurons, and dysregulation of ADARB1 has been implicated in neurological disorders, including Alzheimer's disease and Parkinson's disease. 3. **Cancer:** ADARB1 is involved in the regulation of cell cycle, and dysregulation of ADARB1 can contribute to cancer development and progression. 4. **Immune-Mediated Diseases:** ADARB1 plays a critical role in the innate immune response, and dysregulation of ADARB1 can contribute to immune-mediated diseases, including rheumatoid arthritis and lupus. In conclusion, ADARB1 is a critical gene involved in RNA editing, immune response, and various cellular processes. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms of ADARB1 and its role in disease pathogenesis.

Genular Protein ID: 91027349

Symbol: RED1_HUMAN

Name: RNA-editing deaminase 1

UniProtKB Accession Codes:

P78563 A6NFK8 A6NJ84 C3TTQ1 C3TTQ2 C9JUP4 G5E9B4 O00395 O00465 O00691 O00692 P78555 Q4AE77 Q4AE79 Q6P0M9 Q8NFA1 Q8NFD1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CTD 1 ChEBI 17 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 24 Ensembl 8 EvolutionaryTrace 1 ExpressionAtlas 1 GO 34 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 10 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 2 RefSeq 13 Rhea 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9149227

Title: Two forms of human double-stranded RNA-specific editase 1 (hRED1) generated by the insertion of an Alu cassette.

PubMed ID: 9149227

PubMed ID: 9143496

Title: Cloning of a human RNA editing deaminase (ADARB1) of glutamate receptors that maps to chromosome 21q22.3.

PubMed ID: 9143496

DOI: 10.1006/geno.1997.4655

PubMed ID: 9111310

Title: Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases.

PubMed ID: 9111310

DOI: 10.1128/mcb.17.5.2413

PubMed ID: 9330641

Title: Map location, genomic organization and expression patterns of the human RED1 RNA editase.

PubMed ID: 9330641

DOI: 10.1007/bf02679972

PubMed ID: 12459255

Title: Phylogenetic comparison of the pre-mRNA adenosine deaminase ADAR2 genes and transcripts: conservation and diversity in editing site sequence and alternative splicing patterns.

PubMed ID: 12459255

DOI: 10.1016/s0378-1119(02)01016-8

PubMed ID: 16297572

Title: Novel splice variants of human ADAR2 mRNA: skipping of the exon encoding the dsRNA-binding domains, and multiple C-terminal splice sites.

PubMed ID: 16297572

DOI: 10.1016/j.gene.2005.07.028

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19156214

Title: Novel exon of mammalian ADAR2 extends open reading frame.

PubMed ID: 19156214

DOI: 10.1371/journal.pone.0004225

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 18178553

Title: Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation.

PubMed ID: 18178553

DOI: 10.1074/jbc.m708316200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20192758

Title: Functions and regulation of RNA editing by ADAR deaminases.

PubMed ID: 20192758

DOI: 10.1146/annurev-biochem-060208-105251

PubMed ID: 19908260

Title: Human BLCAP transcript: new editing events in normal and cancerous tissues.

PubMed ID: 19908260

DOI: 10.1002/ijc.25022

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22022963

Title: RNA editing catalyzed by ADAR1 and its function in mammalian cells.

PubMed ID: 22022963

DOI: 10.1134/s0006297911080050

PubMed ID: 21289159

Title: ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor.

PubMed ID: 21289159

DOI: 10.1099/vir.0.028043-0

PubMed ID: 21182352

Title: Adenosine deaminases acting on RNA, RNA editing, and interferon action.

PubMed ID: 21182352

DOI: 10.1089/jir.2010.0097

PubMed ID: 21211811

Title: Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral.

PubMed ID: 21211811

DOI: 10.1016/j.virol.2010.12.004

PubMed ID: 22988838

Title: A-to-I editing of protein coding and noncoding RNAs.

PubMed ID: 22988838

DOI: 10.3109/10409238.2012.714350

PubMed ID: 21769729

Title: ADAR proteins: structure and catalytic mechanism.

PubMed ID: 21769729

DOI: 10.1007/82_2011_144

PubMed ID: 22113393

Title: Activity regulation of adenosine deaminases acting on RNA (ADARs).

PubMed ID: 22113393

DOI: 10.1007/s12035-011-8220-2

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 16141067

Title: Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing.

PubMed ID: 16141067

DOI: 10.1126/science.1113150

PubMed ID: 32220291

Title: Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures.

PubMed ID: 32220291

DOI: 10.1016/j.ajhg.2020.02.015

Sequence Information:

  • Length: 741
  • Mass: 80763
  • Checksum: 02B583414DD59C20
  • Sequence:
    • MDIEDEENMS SSSTDVKENR NLDNVSPKDG STPGPGEGSQ LSNGGGGGPG RKRPLEEGSN 
GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYTLLSQ TGPVHAPLFV MSVEVNGQVF 
EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF 
ETPDKAEPPF YVGSNGDDSF SSSGDLSLSA SPVPASLAQP PLPVLPPFPP PSGKNPVMIL 
NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALAAIFNLH 
LDQTPSRQPI PSEGLQLHLP QVLADAVSRL VLGKFGDLTD NFSSPHARRK VLAGVVMTTG 
TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYTQ LELYLNNKDD 
QKRSIFQKSE RGGFRLKENV QFHLYISTSP CGDARIFSPH EPILEGSRSY TQAGVQWCNH 
GSLQPRPPGL LSDPSTSTFQ GAGTTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ 
TWDGVLQGER LLTMSCSDKI ARWNVVGIQG SLLSIFVEPI YFSSIILGSL YHGDHLSRAM 
YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDSAIE VINATTGKDE 
LGRASRLCKH ALYCRWMRVH GKVPSHLLRS KITKPNVYHE SKLAAKEYQA AKARLFTAFI 
KAGLGAWVEK PTEQDQFSLT P

Genular Protein ID: 4078934013

Symbol: A0A994J4V7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A994J4V7

Database IDs:

CDD 2 CTD 1 EMBL 3 Ensembl 2 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 5 NCBI Taxonomy 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 733
  • Mass: 80117
  • Checksum: 582F10E015A4AA6A
  • Sequence:
    • MASSTTGPLH MGTFFSIMGR RYKRRRKKRS ERKDRNSLRQ SRNPQKYFAM DIEDEENMSS 
SSTDVKENRN LDNVSPKDGS TPGPGEGSQL SNGGGGGPGR KRPLEEGSNG HSKYRLKKRR 
KTPGPVLPKN ALMQLNEIKP GLQYTLLSQT GPVHAPLFVM SVEVNGQVFE GSGPTKKKAK 
LHAAEKALRS FVQFPNASEA HLAMGRTLSV NTDFTSDQAD FPDTLFNGFE TPDKAEPPFY 
VGSNGDDSFS SSGDLSLSAS PVPASLAQPP LPVLPPFPPP SGKNPVMILN ELRPGLKYDF 
LSESGESHAK SFVMSVVVDG QFFEGSGRNK KLAKARAAQS ALAAIFNLHL DQTPSRQPIP 
SEGLQLHLPQ VLADAVSRLV LGKFGDLTDN FSSPHARRKV LAGVVMTTGT DVKDAKVISV 
STGTKCINGE YMSDRGLALN DCHAEIISRR SLLRFLYTQL ELYLNNKDDQ KRSIFQKSER 
GGFRLKENVQ FHLYISTSPC GDARIFSPHE PILEGSRSYT QAGVQWCNHG SLQPRPPGLL 
SDPSTSTFQG AGTTEPADRH PNRKARGQLR TKIESGEGTI PVRSNASIQT WDGVLQGERL 
LTMSCSDKIA RWNVVGIQGS LLSIFVEPIY FSSIILGSLY HGDHLSRAMY QRISNIEDLP 
PLYTLNKPLL SGISNAEARQ PGKAPNFSVN WTVGDSAIEV INATTGKDEL GRASRLCSLP 
LTTLQDYQAQ RVP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.