Details for: BBS7 DT

Gene ID: 119545622

Symbol: BBS7 DT

Ensembl ID: ENSG00000261501

Description: BBS7 divergent transcript

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.6034
    Cell Significance Index: 3.2900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3157
    Cell Significance Index: 19.9000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1923
    Cell Significance Index: 4.2100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.1152
    Cell Significance Index: 2.1300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0671
    Cell Significance Index: 3.0400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.0487
    Cell Significance Index: 0.7000
  • Cell Name: helper T cell (CL0000912)
    Fold Change: 0.0310
    Cell Significance Index: 0.4400
  • Cell Name: obsolete animal cell (CL0000548)
    Fold Change: 0.0232
    Cell Significance Index: 0.2400
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.0029
    Cell Significance Index: 0.0400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0004
    Cell Significance Index: -0.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0006
    Cell Significance Index: -0.4700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0009
    Cell Significance Index: -0.5100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0010
    Cell Significance Index: -0.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0014
    Cell Significance Index: -0.6400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0022
    Cell Significance Index: -3.9900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0025
    Cell Significance Index: -3.9200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0025
    Cell Significance Index: -0.4300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0028
    Cell Significance Index: -1.5400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0033
    Cell Significance Index: -2.4700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0034
    Cell Significance Index: -0.1600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0057
    Cell Significance Index: -2.0400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0061
    Cell Significance Index: -1.2200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0079
    Cell Significance Index: -2.2700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0093
    Cell Significance Index: -0.4000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0096
    Cell Significance Index: -0.5000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0109
    Cell Significance Index: -1.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0134
    Cell Significance Index: -2.6500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0143
    Cell Significance Index: -2.0800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0158
    Cell Significance Index: -0.4300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0161
    Cell Significance Index: -1.9800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0163
    Cell Significance Index: -2.2400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0172
    Cell Significance Index: -1.7600
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: -0.0184
    Cell Significance Index: -0.1800
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.0217
    Cell Significance Index: -0.2800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0248
    Cell Significance Index: -1.3000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0282
    Cell Significance Index: -0.7000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0297
    Cell Significance Index: -0.7200
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.0312
    Cell Significance Index: -0.3400
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0336
    Cell Significance Index: -0.6700
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0386
    Cell Significance Index: -0.6200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0387
    Cell Significance Index: -0.8100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0389
    Cell Significance Index: -1.2800
  • Cell Name: adipocyte (CL0000136)
    Fold Change: -0.0398
    Cell Significance Index: -0.5300
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.0398
    Cell Significance Index: -0.4300
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.0415
    Cell Significance Index: -0.3000
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0433
    Cell Significance Index: -0.3000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0435
    Cell Significance Index: -1.3900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0447
    Cell Significance Index: -2.5100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0468
    Cell Significance Index: -0.6700
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0473
    Cell Significance Index: -0.6300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0483
    Cell Significance Index: -1.6800
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0493
    Cell Significance Index: -0.5100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0496
    Cell Significance Index: -1.5900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0517
    Cell Significance Index: -0.6900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0537
    Cell Significance Index: -1.8800
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0552
    Cell Significance Index: -0.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0557
    Cell Significance Index: -2.6200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0566
    Cell Significance Index: -1.6300
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0567
    Cell Significance Index: -0.6900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0579
    Cell Significance Index: -1.4500
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0593
    Cell Significance Index: -1.4800
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.0594
    Cell Significance Index: -0.6000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0608
    Cell Significance Index: -0.8300
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0613
    Cell Significance Index: -0.8600
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0619
    Cell Significance Index: -0.8500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0627
    Cell Significance Index: -1.3600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0627
    Cell Significance Index: -0.7100
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.0640
    Cell Significance Index: -0.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0651
    Cell Significance Index: -2.8800
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.0661
    Cell Significance Index: -0.4100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0662
    Cell Significance Index: -1.9500
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.0668
    Cell Significance Index: -0.4200
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0669
    Cell Significance Index: -0.7900
  • Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
    Fold Change: -0.0683
    Cell Significance Index: -0.6900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0690
    Cell Significance Index: -1.4400
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: -0.0712
    Cell Significance Index: -0.8600
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0727
    Cell Significance Index: -1.2400
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.0741
    Cell Significance Index: -0.8400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0743
    Cell Significance Index: -1.9900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0747
    Cell Significance Index: -1.5900
  • Cell Name: basal-myoepithelial cell of mammary gland (CL0002324)
    Fold Change: -0.0756
    Cell Significance Index: -0.5600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0758
    Cell Significance Index: -2.8700
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0760
    Cell Significance Index: -1.0100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0771
    Cell Significance Index: -2.7100
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0787
    Cell Significance Index: -1.1800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0791
    Cell Significance Index: -0.8600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0807
    Cell Significance Index: -1.6200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0824
    Cell Significance Index: -1.6300
  • Cell Name: paneth cell (CL0000510)
    Fold Change: -0.0836
    Cell Significance Index: -0.8700
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: -0.0858
    Cell Significance Index: -1.3800
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.0872
    Cell Significance Index: -1.0300
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.0906
    Cell Significance Index: -0.9400
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0930
    Cell Significance Index: -2.3700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0958
    Cell Significance Index: -2.5200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0960
    Cell Significance Index: -1.6600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0965
    Cell Significance Index: -1.9000
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0981
    Cell Significance Index: -1.4300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1000
    Cell Significance Index: -3.6700
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: -0.1026
    Cell Significance Index: -1.0900
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.1036
    Cell Significance Index: -1.4100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The BBS7 DT gene is a divergent transcript, meaning it is transcribed into multiple distinct mRNAs, each with a unique 5' untranslated region (UTR) and coding sequence. This unique feature allows for the production of multiple proteins from a single gene, potentially enabling the gene to regulate multiple cellular processes. The divergent transcript of BBS7 DT is significantly expressed in various cell types, suggesting its involvement in multiple physiological and pathological processes. **Pathways and Functions:** The signaling pathways and functions of BBS7 DT are not yet fully understood. However, based on its expression in various cell types, it is likely involved in regulating cellular processes such as cell migration, differentiation, and survival. The divergent transcript of BBS7 DT may also be involved in modulating the immune response, as it is expressed in B cells, natural killer cells, and other immune cells. Furthermore, its expression in cerebral cortex GABAergic interneurons and forebrain radial glial cells suggests a potential role in neural development and function. **Clinical Significance:** The clinical significance of BBS7 DT is an area of ongoing research. However, its expression in various cell types and tissues suggests that it may be involved in multiple diseases. For example, its expression in intestinal crypt stem cells and absorptive cells suggests a potential role in gastrointestinal disorders, such as inflammatory bowel disease. Additionally, its expression in B cells and natural killer cells may be relevant to immunological disorders, such as autoimmune diseases or cancer. The divergent transcript of BBS7 DT may also be involved in neurological disorders, such as Alzheimer's disease or Parkinson's disease, given its expression in cerebral cortex GABAergic interneurons and forebrain radial glial cells. Further research is needed to fully understand the functional significance of BBS7 DT and its potential role in human disease. **Conclusion:** In conclusion, the BBS7 DT gene is a complex and multifunctional gene that is significantly expressed in various cell types and tissues. Its divergent transcript and unique expression pattern suggest that it may be involved in multiple physiological and pathological processes. Further research is needed to fully understand the functional significance of BBS7 DT and its potential role in human disease. As an expert immunologist, it is essential to continue studying this gene to unravel its mysteries and uncover its clinical significance.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.