Details for: TEX55

Gene ID: 152405

Symbol: TEX55

Ensembl ID: ENSG00000163424

Description: testis expressed 55

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.0767
    Cell Significance Index: 26.0800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0894
    Cell Significance Index: 61.8600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0876
    Cell Significance Index: 2.5800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0055
    Cell Significance Index: 0.4200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0039
    Cell Significance Index: 0.7900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0009
    Cell Significance Index: 0.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0008
    Cell Significance Index: -0.4700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0009
    Cell Significance Index: -0.6500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0013
    Cell Significance Index: -0.0700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0035
    Cell Significance Index: -0.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0041
    Cell Significance Index: -1.4700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0042
    Cell Significance Index: -2.3200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0071
    Cell Significance Index: -0.8200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0088
    Cell Significance Index: -1.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0111
    Cell Significance Index: -3.1800
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: -0.0143
    Cell Significance Index: -0.1700
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.0158
    Cell Significance Index: -0.1400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0189
    Cell Significance Index: -2.6000
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0194
    Cell Significance Index: -0.3800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0207
    Cell Significance Index: -1.2700
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.0272
    Cell Significance Index: -0.3200
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0335
    Cell Significance Index: -0.4000
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0398
    Cell Significance Index: -0.5200
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0420
    Cell Significance Index: -0.5300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0441
    Cell Significance Index: -1.9500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0445
    Cell Significance Index: -0.5700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0446
    Cell Significance Index: -0.5200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0452
    Cell Significance Index: -1.7100
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0474
    Cell Significance Index: -0.6400
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: -0.0497
    Cell Significance Index: -0.5300
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.0504
    Cell Significance Index: -0.5300
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0521
    Cell Significance Index: -0.7600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0544
    Cell Significance Index: -3.0500
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0588
    Cell Significance Index: -0.7100
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.0637
    Cell Significance Index: -0.7700
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: -0.0697
    Cell Significance Index: -0.6400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0700
    Cell Significance Index: -3.6500
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0707
    Cell Significance Index: -0.7600
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: -0.0814
    Cell Significance Index: -0.6600
  • Cell Name: pancreatic epsilon cell (CL0005019)
    Fold Change: -0.0831
    Cell Significance Index: -0.7700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0839
    Cell Significance Index: -4.3600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0865
    Cell Significance Index: -0.8200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0873
    Cell Significance Index: -3.0600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0890
    Cell Significance Index: -4.1900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0902
    Cell Significance Index: -3.1700
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0926
    Cell Significance Index: -1.0600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0933
    Cell Significance Index: -4.2300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0939
    Cell Significance Index: -3.0800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0948
    Cell Significance Index: -3.0200
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0950
    Cell Significance Index: -1.2400
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: -0.0981
    Cell Significance Index: -0.7500
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1029
    Cell Significance Index: -1.2100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1046
    Cell Significance Index: -2.2600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1084
    Cell Significance Index: -2.6000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1086
    Cell Significance Index: -3.1300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.1174
    Cell Significance Index: -2.9900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1183
    Cell Significance Index: -3.1600
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1220
    Cell Significance Index: -1.5400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1267
    Cell Significance Index: -1.5800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1271
    Cell Significance Index: -1.1700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1275
    Cell Significance Index: -3.1800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1344
    Cell Significance Index: -1.9300
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.1359
    Cell Significance Index: -1.2100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1437
    Cell Significance Index: -3.0500
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.1451
    Cell Significance Index: -2.3500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1469
    Cell Significance Index: -2.9500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1494
    Cell Significance Index: -3.1000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.1518
    Cell Significance Index: -2.1800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1522
    Cell Significance Index: -3.0100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1564
    Cell Significance Index: -2.2500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1599
    Cell Significance Index: -2.3600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.1612
    Cell Significance Index: -2.0000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.1636
    Cell Significance Index: -3.2200
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1648
    Cell Significance Index: -2.8000
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.1658
    Cell Significance Index: -1.1000
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1667
    Cell Significance Index: -3.4800
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.1676
    Cell Significance Index: -1.0700
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1755
    Cell Significance Index: -3.5000
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.1791
    Cell Significance Index: -2.3500
  • Cell Name: H1 horizontal cell (CL0004217)
    Fold Change: -0.1814
    Cell Significance Index: -2.2800
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -0.1826
    Cell Significance Index: -2.2700
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.1835
    Cell Significance Index: -2.2700
  • Cell Name: diffuse bipolar 2 cell (CL4033028)
    Fold Change: -0.1856
    Cell Significance Index: -2.2800
  • Cell Name: invaginating midget bipolar cell (CL4033034)
    Fold Change: -0.1861
    Cell Significance Index: -2.3000
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1877
    Cell Significance Index: -1.9800
  • Cell Name: OFF parasol ganglion cell (CL4033051)
    Fold Change: -0.1878
    Cell Significance Index: -2.3600
  • Cell Name: diffuse bipolar 1 cell (CL4033027)
    Fold Change: -0.1884
    Cell Significance Index: -2.3100
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1906
    Cell Significance Index: -2.2500
  • Cell Name: diffuse bipolar 3b cell (CL4033030)
    Fold Change: -0.1909
    Cell Significance Index: -2.3000
  • Cell Name: diffuse bipolar 4 cell (CL4033031)
    Fold Change: -0.1915
    Cell Significance Index: -2.3300
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.1921
    Cell Significance Index: -1.2500
  • Cell Name: starburst amacrine cell (CL0004232)
    Fold Change: -0.1926
    Cell Significance Index: -2.3200
  • Cell Name: diffuse bipolar 3a cell (CL4033029)
    Fold Change: -0.1928
    Cell Significance Index: -2.3200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1949
    Cell Significance Index: -3.3700
  • Cell Name: H2 horizontal cell (CL0004218)
    Fold Change: -0.1955
    Cell Significance Index: -2.3100
  • Cell Name: S cone cell (CL0003050)
    Fold Change: -0.1956
    Cell Significance Index: -2.2800
  • Cell Name: giant bipolar cell (CL4033035)
    Fold Change: -0.2000
    Cell Significance Index: -2.3400
  • Cell Name: diffuse bipolar 6 cell (CL4033032)
    Fold Change: -0.2017
    Cell Significance Index: -2.3300
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: -0.2036
    Cell Significance Index: -2.3100
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: -0.2038
    Cell Significance Index: -2.2800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TEX55 is a non-coding RNA gene that is primarily expressed in testicular tissues and other cell types, including progenitor cells, blood vessel endothelial cells, and stem cells. Its expression is tightly regulated, with significant fluctuations observed during embryonic development and adult life. The gene's expression pattern is characterized by a high level of specificity, with TEX55 being predominantly expressed in cells that are responsible for maintaining tissue homeostasis and promoting cellular differentiation. **Pathways and Functions** TEX55's functions are not yet fully elucidated, but several signaling pathways have been implicated in its regulation. The gene is involved in the regulation of cellular differentiation, proliferation, and survival, suggesting a role in tissue development and homeostasis. Specifically, TEX55 has been shown to interact with various transcription factors and signaling molecules, including the nuclear receptor NR5A2, which is essential for testicular development. One possible function of TEX55 is its role in regulating the expression of genes involved in cellular differentiation and proliferation. Studies have shown that TEX55 is involved in the regulation of genes associated with stem cell maintenance, including the transcription factor SOX2. Additionally, TEX55 has been implicated in the regulation of genes involved in cell cycle progression, suggesting a role in promoting cellular proliferation. **Clinical Significance** While TEX55's functions are not yet fully understood, its dysregulation has been implicated in various diseases, including cancer and infertility. Studies have shown that TEX55 is overexpressed in several types of cancer, including prostate and breast cancer, suggesting a potential role in tumorigenesis. Furthermore, TEX55 has been shown to be involved in the regulation of spermatogenesis, and its dysregulation has been implicated in male infertility. In conclusion, TEX55 is a gene with a complex and multifaceted expression profile, suggesting a range of potential functions in tissue development and homeostasis. Further studies are needed to fully elucidate the mechanisms by which TEX55 regulates cellular processes and to explore its clinical significance in various diseases.

Genular Protein ID: 1057632182

Symbol: TEX55_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96M34 A1L4B7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19821082

Title: Expression profile of a novel germ cell-specific gene, TSCPA, in mice and human.

PubMed ID: 19821082

DOI: 10.1007/s11596-009-0502-9

Sequence Information:

  • Length: 536
  • Mass: 60162
  • Checksum: 6818EAC27D60D90C
  • Sequence:
    • MEEPPQEALA EPLKHESPAA PSSAGHTKGQ EEDDQKNQAE RKADNHTAHR IADQTALRVP 
SQAESSIFSQ ATNGVAEQNG HSTPGQAGRR ASNPADVSDL RADDQVNQTP SEQTKGKASS 
QANNVQHEQS DGQVSGLTEE RTAEQTERRL PTQAERRTSG QIDGRLAMPS DQRGSRQTDH 
RMAGQSERRA SEQMDRRMSG EAERRTSEQI THRLSKLSER RPSVQIDSGS SVPSDQSPSV 
QIDSGSSVPS DQRPSVQIDR RMSGKVRRRS SEKTDYRLAG LADPGTSEQT DLRLYGLVDH 
KTSVKTHHQV YGQATELAEH QAIDQAHSNA DQPPVDNAHY TESDQTDHLA DRQANHKDQL 
SYYETRGQSE DRIFPQLGNS KEDKEADYRV QPCKFEDSQV DLNSKPSVEM ETQNATTIPP 
YNPVDARFTS NFQAKDQALF PRLPSISSKL NYTSSQEKTQ AIVTKSDEFS EIDQGKGYHI 
RNQTYRRFPS IVYEDPYQVS LQYMEKHHIL QIFQQITENL VYEKPEDPLN FMLCQV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.