Details for: DNAH6

Gene ID: 1768

Symbol: DNAH6

Ensembl ID: ENSG00000115423

Description: dynein axonemal heavy chain 6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 134.2375
    Cell Significance Index: -20.8800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 82.2415
    Cell Significance Index: -20.8600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 15.9205
    Cell Significance Index: -15.2000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.7565
    Cell Significance Index: 166.1600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.4181
    Cell Significance Index: 129.4400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.5214
    Cell Significance Index: 169.5400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7881
    Cell Significance Index: 358.7000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.0330
    Cell Significance Index: 29.4800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.8298
    Cell Significance Index: 18.1700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.7231
    Cell Significance Index: 137.6100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.6339
    Cell Significance Index: 92.1500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5017
    Cell Significance Index: 179.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4051
    Cell Significance Index: 80.3900
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.3557
    Cell Significance Index: 3.4800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.3311
    Cell Significance Index: 4.9900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3217
    Cell Significance Index: 31.8200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3100
    Cell Significance Index: 169.3100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2742
    Cell Significance Index: 189.6300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2129
    Cell Significance Index: 192.2000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1796
    Cell Significance Index: 4.4900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1598
    Cell Significance Index: 26.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1214
    Cell Significance Index: 228.6700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1096
    Cell Significance Index: 11.9200
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.1086
    Cell Significance Index: 1.0800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1003
    Cell Significance Index: 5.6300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0511
    Cell Significance Index: 3.0700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0442
    Cell Significance Index: 28.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0382
    Cell Significance Index: 70.4600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0195
    Cell Significance Index: 29.9900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0159
    Cell Significance Index: 0.9800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0143
    Cell Significance Index: 0.6500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0134
    Cell Significance Index: 5.9300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0084
    Cell Significance Index: -11.4500
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0200
    Cell Significance Index: -0.1900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0213
    Cell Significance Index: -15.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0219
    Cell Significance Index: -1.3800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0237
    Cell Significance Index: -17.5200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0268
    Cell Significance Index: -12.1700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0316
    Cell Significance Index: -23.9400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0326
    Cell Significance Index: -0.9400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0379
    Cell Significance Index: -21.3800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0385
    Cell Significance Index: -24.0200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0415
    Cell Significance Index: -0.9000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0437
    Cell Significance Index: -0.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0498
    Cell Significance Index: -1.7500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0572
    Cell Significance Index: -16.4700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0583
    Cell Significance Index: -1.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0776
    Cell Significance Index: -13.9900
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.0783
    Cell Significance Index: -0.4100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0811
    Cell Significance Index: -5.6100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0850
    Cell Significance Index: -5.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1035
    Cell Significance Index: -17.6800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1083
    Cell Significance Index: -13.8800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1131
    Cell Significance Index: -13.9100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1182
    Cell Significance Index: -24.8900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1314
    Cell Significance Index: -18.0500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1425
    Cell Significance Index: -18.4100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1485
    Cell Significance Index: -3.0800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1658
    Cell Significance Index: -5.3100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1669
    Cell Significance Index: -19.6900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1713
    Cell Significance Index: -19.6300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1730
    Cell Significance Index: -20.1600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1783
    Cell Significance Index: -18.2200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1785
    Cell Significance Index: -18.5900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1929
    Cell Significance Index: -14.3800
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.1949
    Cell Significance Index: -2.1100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2016
    Cell Significance Index: -6.6000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2029
    Cell Significance Index: -14.3500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2037
    Cell Significance Index: -3.4900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.2073
    Cell Significance Index: -2.6100
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.2090
    Cell Significance Index: -1.9200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2092
    Cell Significance Index: -4.5200
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.2203
    Cell Significance Index: -3.1300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2213
    Cell Significance Index: -16.9800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2269
    Cell Significance Index: -3.2500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2337
    Cell Significance Index: -18.5100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2386
    Cell Significance Index: -7.6000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2915
    Cell Significance Index: -12.6800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2939
    Cell Significance Index: -15.3100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3188
    Cell Significance Index: -20.5700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3274
    Cell Significance Index: -6.3900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3500
    Cell Significance Index: -16.4500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3598
    Cell Significance Index: -8.6300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3665
    Cell Significance Index: -12.8400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3775
    Cell Significance Index: -19.6100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3811
    Cell Significance Index: -17.7700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3846
    Cell Significance Index: -4.1900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4041
    Cell Significance Index: -10.0800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4154
    Cell Significance Index: -21.8100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4184
    Cell Significance Index: -8.4000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4220
    Cell Significance Index: -9.7500
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.4286
    Cell Significance Index: -5.0000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4388
    Cell Significance Index: -11.2800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4529
    Cell Significance Index: -9.6800
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.4594
    Cell Significance Index: -7.5700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4698
    Cell Significance Index: -9.2900
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.4863
    Cell Significance Index: -4.6100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4952
    Cell Significance Index: -10.5100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4971
    Cell Significance Index: -13.5300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.5121
    Cell Significance Index: -3.4700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DNAH6 is a member of the dynein heavy chain family, which is composed of six subunits (α, β, γ, δ, ε, and ζ). The β subunits, including DNAH6, are crucial for the assembly and function of the dynein complex. DNAH6 is specifically localized to the axoneme, where it interacts with other dynein subunits to form the dynein complex. The protein exhibits a conserved structure, with a long N-terminal domain and a shorter C-terminal domain. DNAH6 is also characterized by its ability to bind to microtubules and participate in minus-end-directed motility. **Pathways and Functions:** DNAH6 is integral to the dynein complex, which is responsible for the movement of cilia and axonemes. The dynein complex is composed of multiple subunits, including DNAH6, that work together to generate force and propel cilia. The minus-end-directed microtubule motor activity of DNAH6 enables the coordinated movement of cilia, which is essential for various cellular functions, including: 1. **Cilia movement**: DNAH6 is essential for the movement of cilia, which is critical for sensing the extracellular environment, regulating cell signaling, and maintaining cellular homeostasis. 2. **Axoneme maintenance**: DNAH6 is involved in the assembly and maintenance of the axoneme, which is essential for the proper functioning of cilia and flagella. 3. **Cell motility**: DNAH6 is also involved in the motility of cells, including neurons and epithelial cells, where it plays a crucial role in the movement of cells and the regulation of cellular behavior. **Clinical Significance:** Dysregulation of DNAH6 has been implicated in various human diseases, including: 1. **Kartagener syndrome**: A rare genetic disorder characterized by chronic sinusitis, bronchiectasis, and situs inversus, which is caused by mutations in the DNAH5 gene, but DNAH6 has been found to be mutated in some cases. 2. **Primary ciliary dyskinesia (PCD)**: A group of disorders characterized by defective ciliary function, which is caused by mutations in multiple genes, including DNAH5 and DNAH6. 3. **Neurological disorders**: DNAH6 has been implicated in the pathogenesis of various neurological disorders, including Parkinson's disease, Alzheimer's disease, and autism spectrum disorder. In conclusion, DNAH6 is a critical component of the dynein complex, which plays a pivotal role in the movement and maintenance of cilia. Its dysregulation has been implicated in various human diseases, highlighting the importance of this gene in maintaining cellular homeostasis and regulating cellular behavior. Further research is necessary to elucidate the mechanisms underlying DNAH6-mediated functions and to develop therapeutic strategies for the treatment of diseases associated with DNAH6 dysfunction.

Genular Protein ID: 2873524810

Symbol: DYH6_HUMAN

Name: Axonemal beta dynein heavy chain 6

UniProtKB Accession Codes:

Q9C0G6 A0PJN9 B5MEE0 B7ZL99 O95493 Q53QZ1 Q53TE5 Q8N1W6 Q92861 Q96BL6 Q9H030 Q9H5E1

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 5 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 16 EMDB 1 Ensembl 1 GO 10 Gene3D 13 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 18 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 11 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 RefSeq 4 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8812413

Title: Multiple mouse chromosomal loci for dynein-based motility.

PubMed ID: 8812413

DOI: 10.1006/geno.1996.0422

PubMed ID: 11175280

Title: Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

PubMed ID: 11175280

DOI: 10.1038/sj.ejhg.5200555

PubMed ID: 11214970

Title: Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 11214970

DOI: 10.1093/dnares/7.6.347

PubMed ID: 28206990

Title: A familial study of azoospermic men identifies three novel causative mutations in three new human azoospermia genes.

PubMed ID: 28206990

DOI: 10.1038/gim.2016.225

Sequence Information:

  • Length: 4158
  • Mass: 475983
  • Checksum: 8ADAA07BC375F683
  • Sequence:
    • MTFRATDSEF DLTNIEEYAE NSALSRLNNI KAKQRVSYVT STENESDTQI LTFRHITKAQ 
EKTRKRQQPI KLEPLPVLKV YQDHKQPEYI HEQNRFQLMT AGIIKRPVSI AKKSFATSST 
QFLEHQDAVK KMQIHRPYVE VFSPSPPKLP HTGIGKRGLF GTRSSAYPKY TFHDREEVVK 
ANIRDPLQII KIIRENEHLG FLYMIPAVPR SSIEYDTYNL KVVSYENINK NDYYTISQRA 
VTHIYNEDIE FIEIDRWEQE YLYHRELTKI PIFSLFRKWK AFSVWRKNVR SKKITGCQKS 
LQKNLFIVNP HLRPALLKIN ELCYHLSFMG LCYIEKCHTY TLQEFKAAQV IRLAEVTERL 
GEFRNEAKYV VRRACRFALR AAGFVPDDCA FGPFEDYHKV QSSGSFINTP HELPTYGDSE 
KMTYTEQASK RHYCMRLTCF IRLNDYLIEN TMHILTVNAV NSLLNHLTDK LKRTPSADVI 
QKWITEEKPE VPDKKGTLMV EKQEEDESLI PMFLTELMLT VQSLLFEPSL EDFLDGILGA 
VNHCQNTVLS VPNLVPDSYF DAFTSPYINN KLEGKTCGTG PSLAAVFEDD KNFHTIISQI 
KETIQAAFES ARIYAATFEK FQIFFKENES LDLQALKLQE PDINFFSEQL EKYHKQHKDA 
VALRPTRNVG LLLIDTRLLR EKLIPSPLRC LEVLNFMLPR QSKKKVDAII FEAQDAEYKL 
EFVPTTTTEY VHSLLFLDEI QERIESLEDE GNIVTQMYKL MEQYQVPTPP EDFAVFATMK 
PSIVAVRNAI DKSVGDRESS IKQFCVHLGS DLEELNNEVN EVKLQAQDPQ ILDISADQDK 
IRLILNNLQS VLADLQKRAF QYKSYQKNFK VEVSKFEALE EVSAELKLKQ LLWDSFSEWD 
KLQQEWLKSK FDCLDPEVLN GQVSKYAKFV TQLEKGLPPN SVVPQLKYKV EKMKEKLPVI 
IDLRNPTLKA RHWAAIEQTV DATLVDAEIP LTLERLSQLH VFDFGQEIQD ISGQASGEAA 
LEAILKKVED SWKTTEFVIL PHRDSKDVFI LGGTDDIQVL LDDSTINVAT LASSRYLGPL 
KTRVDEWQKQ LALFNQTLEE WLTCQRNWLY LESIFNAPDI QRQLPAEAKM FLQVDKSWKE 
IMRKVNRLPN ALRAATQPGL LETFQNNNAL LDQIQKCLEA YLESKRVIFP RFYFLSNDEL 
LEILAQTRNP QAVQPHLRKC FDSISKLEFA LMPPAEGKIP GIDGEPEKVY TNDILAMLSP 
EGERVSLGKG LKARGNVEEW LGKVEEAMFT SLRRLCKAAI ADYQGKLRTD WVVAGHPSQV 
ILTVSQIMWC RDLTECLETE HSNHIQALKN FEKVNFERLN ALAAIVQGSL PKLHRNILTA 
LITIDVHARD IVTELVQSKV ETVESFDWQR QLRYYWDIDL DNCVARMALS QYTYGYEYLG 
ACPRLVITPL TDRCYLCLMG ALQLDLGGAP AGPAGTGKTE TTKDLAKALA IQCVVFNCSD 
GLDYKMMGRF FSGLAQSGAW CCFDEFNRID IEVLSVIAQQ LITIRNAKAA KLSRFMFEGR 
EIKLVMTCAA FITMNPGYAG RTELPDNLKA LFRPFAMMVP NYALIAEVIL YSEGFESSKI 
LARKMTQMYK LCSEQLSQQD HYDFGMRAVK SVLVMAGSLK RENPDLNEDV VLIRALQDSN 
LPKFLTDDAL LFSGIISDLF PGVQIPEHDY GILQSTIVDV MNRQNLQPEM CMVRKVIQFY 
ETMLVRHGVM LVGPTGGGKT TVYRILAETL GNLQKLGIEN SFYQAVKTYV LNPKSITMGE 
LYGEVNNLTL EWKDGLMALS VRAAVNDTSE DHKWIISDGP VDALWIENMN TVLDDNKMLC 
LANSERIKLT PQIHMLFEVQ DLRVASPATV SRCGMVFVDP EELKWMPYVK TWMKGISKKL 
TEETQEYILN LFQRYVDEGL HFINKKCSQA IPQVDISKVT TLCCLLESLI LGKDGVNLAM 
EQTKLNTILC QTFVFCYLWS LGGNLTENYY DSFDTFIRTQ FDDNPDARLP NSGDLWSIHM 
DFDTKRLDPW ERIIPTFKYN RDVPFFEMLV PTTDTVRYGY LMEKLLAVKH SVLFTGITGV 
GKSVIAKGLL NKIQESAGYV PVYLNFSAQT SSARTQEIIE SKLERKRKNI LGAPGNKRIV 
IFVDDLNMPR LDRYGSQPPI ELLRQYQDFG GFYDRNKLFW KEIQDVTIIS ACAPPGGGRN 
PVTPRFIRHF SMLCLPMPSE HSLKQIFQAI LNGFLSDFPP AVKQTASSIV EASVEIYNKM 
SVDLLPTPAK SHYVFNLRDL SKCVQGILQC DPGTIREEIQ IFRLFCHECQ RVFHDRLINN 
EDKHYFHVIL TEMANKHFGI AIDLEYFLNK PIIFGDFIKF GADKADRIYD DMPDIEKTAN 
VLQDYLDDYN LTNPKEVKLV FFQDAIEHVS RIARMIRQER GNALLVGVGG TGKQSLTRLA 
AHICGYKCLQ IELSRGYNYD SFHEDLRKLY KMAGVEDKNM VFLFTDTQIV VEEFLEDINN 
ILNSGEVPNL FEKDELEQVL AATRPRAKEV GISEGNRDEV FQYFISKVRQ KLHIVLCMSP 
VGEAFRSRCR MFPSLVNCCT IDWFVQWPRE ALLSVSKTFF SQVDAGNEEL KEKLPLMCVN 
VHLSVSSMAE RYYNELRRRY YTTPTSYLEL INLYLSMLSE KRKQIISARD RVKNGLTKLL 
ETNILVDKMK LDLSALEPVL LAKSEDVEAL MEKLAVDQES ADQVRNTVQE DEATAKVKAE 
ETQAIADDAQ RDLDEALPAL DAANKALDSL DKADISEIRV FTKPPDLVMT VMEAISILLN 
AKPDWPSAKQ LLGDSNFLKR LLEYDKENIK PQILAKLQKY INNPDFVPEK VEKVSKACKS 
MCMWVRAMDL YSRVVKVVEP KRQKLRAAQA ELDITMATLR EKQALLRQVE DQIQALQDEY 
DKGVNEKESL AKTMALTKAR LVRAGKLTAA LEDEQVRWEE SIQKFEEEIS NITGNVFIAA 
ACVAYYGAFT AQYRQSLIEC WIQDCQSLEI PIDPSFSLIN ILGDPYEIRQ WNTDGLPRDL 
ISTENGILVT QGRRWPLMID PQDQANRWIR NKESKSGLKI IKLTDSNFLR ILENSIRLGL 
PVLLEELKET LDPALEPILL KQIFISGGRL LIRLGDSDID YDKNFRFYMT TKMPNPHYLP 
EVCIKVTIIN FTVTKSGLED QLLSDVVRLE KPRLEEQRIK LIVRINTDKN QLKTIEEKIL 
RMLFTSEGNI LDNEELIDTL QDSKITSGAI KTRLEEAEST EQMINVAREK YRPVATQGSV 
MYFVIASLSE IDPMYQYSLK YFKQLFNTTI ETSVKTENLQ QRLDVLLEQT LLTAYVNVSR 
GLFEQHKLIY SFMLCVEMMR QQGTLSDAEW NFFLRGSAGL EKERPPKPEA PWLPTATWFA 
CCDLEESFPV FHGLTQNILS HPISIRLGSF ETYINPQKWE GYSKMKHEDK HMRQEKEAAH 
QDPWSAGLSS FHKLILIKCC KEEKVVFALT DFVIENLGKQ FIETPPVDLP TLYQDMSCNT 
PLVFILSTGS DPMGAFQRFA RESGYSERVQ SISLGQGQGP IAEKMVKDAM KSGNWVFLQN 
CHLAVSWMLA MEELIKTFTD PDSAIKDTFR LFLSSMPSNT FPVTVLQNSV KVTNEPPKGL 
RANIRRAFTE MTPSFFEENI LGKKWRQIIF GICFFHAIIQ ERKKFGPLGW NICYEFNDSD 
RECALLNLKL YCKEGKIPWD ALIYITGEIT YGGRVTDSWD QRCLRTILKR FFSPETLEED 
YKYSESGIYF APMADSLQEF KDYIENLPLI DDPEIFGMHE NANLVFQYKE TSTLINTILE 
VQPRSSTGGE GKSNDEIVQE LVASVQTRVP EKLEMEGASE SLFVKDLQGR LNSLTTVLGQ 
EVDRFNNLLK LIHTSLETLN KAIAGFVVMS EEMEKVYNSF LNNQVPALWS NTAYPSLKPL 
GSWVKDLILR TSFVDLWLKR GQPKSYWISG FFFPQGFLTG TLQNHARKYN LPIDELSFKY 
SVIPTYRDQA AVIEAAKTVQ FGQELPMDME LPSPEDGVLV HGMFMDASRW DDKEMVIEDA 
LPGQMNPVLP VVHFEPQQNY KPSPTLYHCP LYKTGARAGT LSTTGHSTNF VVTVLLPSKR 
SKDYWIAKGS ALLCQLSE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.