Details for: DYNC1LI2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 460.3806
Cell Significance Index: -71.6100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 282.5621
Cell Significance Index: -71.6700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 192.2332
Cell Significance Index: -79.1900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 156.2941
Cell Significance Index: -73.7900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 144.0713
Cell Significance Index: -58.5300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 133.8880
Cell Significance Index: -68.8700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 110.1901
Cell Significance Index: -73.9400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 61.4302
Cell Significance Index: -58.6500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 59.8724
Cell Significance Index: -73.8200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 25.7199
Cell Significance Index: -68.9000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 18.8239
Cell Significance Index: -74.2800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 16.8650
Cell Significance Index: -51.8000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.6239
Cell Significance Index: -25.4400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 3.3390
Cell Significance Index: 230.9100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.4017
Cell Significance Index: 125.1000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.2934
Cell Significance Index: 31.2900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.7515
Cell Significance Index: 351.3400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.6358
Cell Significance Index: 324.6400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.5897
Cell Significance Index: 172.9200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.5500
Cell Significance Index: 279.4200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.3187
Cell Significance Index: 162.1500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.2942
Cell Significance Index: 60.3400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.2833
Cell Significance Index: 58.1700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.1802
Cell Significance Index: 34.0100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.0488
Cell Significance Index: 376.2000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.0286
Cell Significance Index: 141.2500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.9086
Cell Significance Index: 496.2300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.9001
Cell Significance Index: 24.5000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.8752
Cell Significance Index: 23.3700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.8509
Cell Significance Index: 52.3000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.8156
Cell Significance Index: 360.5900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.7820
Cell Significance Index: 488.3300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.7400
Cell Significance Index: 38.4400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.6859
Cell Significance Index: 36.0100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6613
Cell Significance Index: 597.1400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.6444
Cell Significance Index: 18.0100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6387
Cell Significance Index: 103.8800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5917
Cell Significance Index: 58.5300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.5397
Cell Significance Index: 69.1900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5371
Cell Significance Index: 371.4600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4986
Cell Significance Index: 94.8900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.4706
Cell Significance Index: 26.4100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4113
Cell Significance Index: 19.3300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.4044
Cell Significance Index: 28.6000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.3801
Cell Significance Index: 13.2100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.3155
Cell Significance Index: 53.8800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1316
Cell Significance Index: 4.6300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1310
Cell Significance Index: 9.7600 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1258
Cell Significance Index: 16.2600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1030
Cell Significance Index: 6.6500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0772
Cell Significance Index: 49.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0653
Cell Significance Index: 122.9900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0500
Cell Significance Index: 3.8400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0326
Cell Significance Index: 60.0400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0225
Cell Significance Index: 34.5900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0154
Cell Significance Index: 20.9600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0008
Cell Significance Index: -0.5900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0072
Cell Significance Index: -0.3200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0217
Cell Significance Index: -9.8300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0398
Cell Significance Index: -29.5000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0440
Cell Significance Index: -33.3200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0897
Cell Significance Index: -50.5600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1130
Cell Significance Index: -11.5500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1256
Cell Significance Index: -8.4400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1268
Cell Significance Index: -4.8000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.1287
Cell Significance Index: -1.1900 - Cell Name: peg cell (CL4033014)
Fold Change: -0.1502
Cell Significance Index: -3.4700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1628
Cell Significance Index: -34.2800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1768
Cell Significance Index: -11.1400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1999
Cell Significance Index: -23.2900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2147
Cell Significance Index: -61.7700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2159
Cell Significance Index: -3.7000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2347
Cell Significance Index: -34.1100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2496
Cell Significance Index: -29.4400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.3203
Cell Significance Index: -6.9400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3274
Cell Significance Index: -5.4800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.3623
Cell Significance Index: -8.6900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3789
Cell Significance Index: -43.2600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3929
Cell Significance Index: -10.3300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4098
Cell Significance Index: -46.9500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.5231
Cell Significance Index: -10.9500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6287
Cell Significance Index: -65.4600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.6614
Cell Significance Index: -18.9600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.6671
Cell Significance Index: -13.0200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.6851
Cell Significance Index: -19.5500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7270
Cell Significance Index: -57.5800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.7654
Cell Significance Index: -16.3000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.9498
Cell Significance Index: -58.2300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -1.0461
Cell Significance Index: -52.8700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.0968
Cell Significance Index: -29.3900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.1468
Cell Significance Index: -36.7300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.3313
Cell Significance Index: -34.2200 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -1.4512
Cell Significance Index: -20.3400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.4649
Cell Significance Index: -47.9600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.4801
Cell Significance Index: -47.1400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -1.5083
Cell Significance Index: -22.6000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -1.5459
Cell Significance Index: -33.8500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.5629
Cell Significance Index: -54.7500 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -1.5641
Cell Significance Index: -9.4500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -1.5680
Cell Significance Index: -57.5600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 271492504
Symbol: DC1L2_HUMAN
Name: Cytoplasmic dynein 1 light intermediate chain 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 29420470
Title: Cryo-EM shows how dynactin recruits two dyneins for faster movement.
PubMed ID: 29420470
DOI: 10.1038/nature25462
PubMed ID: 36071160
Title: Structure of dynein-dynactin on microtubules shows tandem adaptor binding.
PubMed ID: 36071160
Sequence Information:
- Length: 492
- Mass: 54099
- Checksum: AF7B4E49E3983DCC
- Sequence:
MAPVGVEKKL LLGPNGPAVA AAGDLTSEEE EGQSLWSSIL SEVSTRARSK LPSGKNILVF GEDGSGKTTL MTKLQGAEHG KKGRGLEYLY LSVHDEDRDD HTRCNVWILD GDLYHKGLLK FAVSAESLPE TLVIFVADMS RPWTVMESLQ KWASVLREHI DKMKIPPEKM RELERKFVKD FQDYMEPEEG CQGSPQRRGP LTSGSDEENV ALPLGDNVLT HNLGIPVLVV CTKCDAVSVL EKEHDYRDEH LDFIQSHLRR FCLQYGAALI YTSVKEEKNL DLLYKYIVHK TYGFHFTTPA LVVEKDAVFI PAGWDNEKKI AILHENFTTV KPEDAYEDFI VKPPVRKLVH DKELAAEDEQ VFLMKQQSLL AKQPATPTRA SESPARGPSG SPRTQGRGGP ASVPSSSPGT SVKKPDPNIK NNAASEGVLA SFFNSLLSKK TGSPGSPGAG GVQSTAKKSG QKTVLSNVQE ELDRMTRKPD SMVTNSSTEN EA
Genular Protein ID: 3511536041
Symbol: Q63HJ8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 209
- Mass: 23552
- Checksum: FF8FAB33A0230879
- Sequence:
MAPVGVEKKL LLGPNGPAVA AAGDLTSEEE EGQSLWSSIL SEVSTRARSK LPSGKNILVF GEDGSGKTTL MTKLQGAEHG KKGRGLEYLY LSVHDEDRDD HTRCNVWILD GDLYHKGLLK FAVSAESLPE TLVIFVADMS RPWTVMESLQ KWASVLREHI DKMKIPPEKM RELERKFVKD FQDYMEPEEG CQGSPLSNRV EQMRPRNHW
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.