Details for: E2F4

Gene ID: 1874

Symbol: E2F4

Ensembl ID: ENSG00000205250

Description: E2F transcription factor 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 83.1581
    Cell Significance Index: -21.0900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 56.1507
    Cell Significance Index: -26.5100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 56.1221
    Cell Significance Index: -22.8000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 50.3514
    Cell Significance Index: -25.9000
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 27.5161
    Cell Significance Index: -4.2800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 24.2159
    Cell Significance Index: -23.1200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.2074
    Cell Significance Index: -18.7500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.4024
    Cell Significance Index: -19.8300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.3253
    Cell Significance Index: -24.9600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.1637
    Cell Significance Index: -15.8600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.3309
    Cell Significance Index: 79.9000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0725
    Cell Significance Index: 174.4400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.9599
    Cell Significance Index: 25.6300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7748
    Cell Significance Index: 21.0900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6680
    Cell Significance Index: 34.8000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6534
    Cell Significance Index: 45.1900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5767
    Cell Significance Index: 16.6200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5710
    Cell Significance Index: 7.7900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5571
    Cell Significance Index: 15.5700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.5068
    Cell Significance Index: 17.6100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4876
    Cell Significance Index: 87.9000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4706
    Cell Significance Index: 57.8700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4114
    Cell Significance Index: 56.5000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4025
    Cell Significance Index: 80.7400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3737
    Cell Significance Index: 16.9400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3632
    Cell Significance Index: 72.0800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3620
    Cell Significance Index: 25.6000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3593
    Cell Significance Index: 158.8700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3515
    Cell Significance Index: 66.9000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3439
    Cell Significance Index: 40.5600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3342
    Cell Significance Index: 21.5600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.3090
    Cell Significance Index: 3.5100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2972
    Cell Significance Index: 15.4400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2879
    Cell Significance Index: 13.5300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2674
    Cell Significance Index: 7.0300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2381
    Cell Significance Index: 11.1000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2358
    Cell Significance Index: 212.9300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2299
    Cell Significance Index: 125.5400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2278
    Cell Significance Index: 16.9800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1874
    Cell Significance Index: 4.0600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1736
    Cell Significance Index: 4.9800
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.1625
    Cell Significance Index: 1.3700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1493
    Cell Significance Index: 14.7700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1437
    Cell Significance Index: 99.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1273
    Cell Significance Index: 45.6500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1218
    Cell Significance Index: 2.5500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1120
    Cell Significance Index: 14.3600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1057
    Cell Significance Index: 13.6600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.0883
    Cell Significance Index: 0.9600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0758
    Cell Significance Index: 2.0300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0695
    Cell Significance Index: 11.8700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0298
    Cell Significance Index: 1.8800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0284
    Cell Significance Index: 0.8400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.0081
    Cell Significance Index: 0.1500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0005
    Cell Significance Index: 1.0400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0032
    Cell Significance Index: -2.4500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0056
    Cell Significance Index: -4.1400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0079
    Cell Significance Index: -14.6200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0083
    Cell Significance Index: -5.1800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0092
    Cell Significance Index: -0.1900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0095
    Cell Significance Index: -14.6200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0122
    Cell Significance Index: -8.9500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0167
    Cell Significance Index: -22.7500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0184
    Cell Significance Index: -10.3500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0210
    Cell Significance Index: -13.3100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0227
    Cell Significance Index: -0.3800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0284
    Cell Significance Index: -2.9000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0331
    Cell Significance Index: -1.0600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0389
    Cell Significance Index: -17.6500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0424
    Cell Significance Index: -1.4900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0561
    Cell Significance Index: -11.8200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0718
    Cell Significance Index: -20.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0734
    Cell Significance Index: -10.6700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0749
    Cell Significance Index: -3.9300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0810
    Cell Significance Index: -2.0700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0822
    Cell Significance Index: -9.4200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0864
    Cell Significance Index: -10.0700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0963
    Cell Significance Index: -2.0500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1084
    Cell Significance Index: -8.3200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1245
    Cell Significance Index: -14.2100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.1336
    Cell Significance Index: -2.3600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1691
    Cell Significance Index: -11.3700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1792
    Cell Significance Index: -4.4800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2123
    Cell Significance Index: -5.6800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2290
    Cell Significance Index: -23.8500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2447
    Cell Significance Index: -15.0400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2782
    Cell Significance Index: -22.0300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3263
    Cell Significance Index: -18.3100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3500
    Cell Significance Index: -17.6900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3592
    Cell Significance Index: -15.8900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3677
    Cell Significance Index: -22.5500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3933
    Cell Significance Index: -10.1100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4162
    Cell Significance Index: -12.2600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4204
    Cell Significance Index: -2.5400
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.4387
    Cell Significance Index: -2.8600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4513
    Cell Significance Index: -17.0900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4522
    Cell Significance Index: -7.7500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5155
    Cell Significance Index: -18.0600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5477
    Cell Significance Index: -15.6300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5611
    Cell Significance Index: -17.8700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** E2F4 shares structural and functional similarities with other E2F family members, including E2F1, E2F2, and E2F3. It contains a DNA-binding domain, which allows it to interact with specific DNA sequences and regulate transcription. E2F4 is also capable of forming heterodimers with other E2F family members, such as E2F1 and E2F3, to regulate transcriptional activity. Additionally, E2F4 can interact with other transcriptional regulators, such as p107 and p130, to modulate its activity. **Pathways and Functions** E2F4 is involved in various cellular pathways, including: 1. **Cell Cycle Regulation**: E2F4 plays a critical role in regulating the G1/S transition, where it promotes the expression of genes necessary for cell cycle progression. 2. **Transcriptional Regulation**: E2F4 regulates the expression of genes involved in cell cycle progression, apoptosis, and differentiation. 3. **DNA Damage Response**: E2F4 is involved in the response to DNA damage, where it regulates the expression of genes involved in DNA repair and cell cycle arrest. 4. **Apoptosis**: E2F4 can promote apoptosis in certain cell types, such as cancer cells, by regulating the expression of pro-apoptotic genes. **Clinical Significance** E2F4 has been implicated in various diseases, including: 1. **Cancer**: E2F4 is often deregulated in cancer, leading to uncontrolled cell proliferation and tumorigenesis. 2. **Neurological Disorders**: E2F4 has been implicated in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, where it regulates the expression of genes involved in neuronal survival and differentiation. 3. **Immune System Disorders**: E2F4 is involved in the regulation of immune cell development and function, making it a potential target for immunotherapeutic interventions. In conclusion, E2F4 is a critical transcription factor involved in regulating the cell cycle and transcriptional processes. Its dysregulation has been implicated in various diseases, including cancer, neurological disorders, and immune system disorders. Further research is necessary to fully understand the mechanisms of E2F4 regulation and its clinical significance. **Targeting E2F4 in Cancer Therapy** E2F4 is a promising target for cancer therapy due to its involvement in cell cycle regulation and transcriptional control. Inhibitors of E2F4 have been shown to exhibit anti-cancer activity in preclinical studies, suggesting potential therapeutic applications. However, further research is needed to fully understand the mechanisms of E2F4 regulation and to develop effective inhibitors for cancer treatment. **Targeting E2F4 in Neurological Disorders** E2F4 has been implicated in the regulation of neuronal survival and differentiation, making it a potential target for neurological disorders. Inhibitors of E2F4 have been shown to exhibit neuroprotective effects in preclinical studies, suggesting potential therapeutic applications. However, further research is needed to fully understand the mechanisms of E2F4 regulation and to develop effective inhibitors for neurological disorders. **Targeting E2F4 in Immune System Disorders** E2F4 is involved in the regulation of immune cell development and function, making it a potential target for immunotherapeutic interventions. Inhibitors of E2F4 have been shown to exhibit immunomodulatory effects in preclinical studies, suggesting potential therapeutic applications. However, further research is needed to fully understand the mechanisms of E2F4 regulation and to develop effective inhibitors for immune system disorders.

Genular Protein ID: 4278198136

Symbol: E2F4_HUMAN

Name: Transcription factor E2F4

UniProtKB Accession Codes:

Q16254 A6NGR8 B5BU56 Q12991 Q15328

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 10 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 9 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7958924

Title: E2F-4, a new member of the E2F transcription factor family, interacts with p107.

PubMed ID: 7958924

DOI: 10.1101/gad.8.22.2665

PubMed ID: 7958925

Title: E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo.

PubMed ID: 7958925

DOI: 10.1101/gad.8.22.2680

PubMed ID: 7892279

Title: E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle.

PubMed ID: 7892279

DOI: 10.1073/pnas.92.6.2403

PubMed ID: 10797289

Title: Genomic structure and mutation screening of the E2F4 gene in human tumors.

PubMed ID: 10797289

DOI: 10.1002/(sici)1097-0215(20000601)86:5<672::aid-ijc11>3.0.co;2-x

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9074408

Title: The predominant E2F complex in human primary haemopoietic cells and in AML blasts contains E2F-4, DP-1 and p130.

PubMed ID: 9074408

DOI: 10.1046/j.1365-2141.1997.d01-2086.x

PubMed ID: 11418595

Title: E2F transcriptional activation requires TRRAP and GCN5 cofactors.

PubMed ID: 11418595

DOI: 10.1074/jbc.m102067200

PubMed ID: 14532282

Title: HCF-1 functions as a coactivator for the zinc finger protein Krox20.

PubMed ID: 14532282

DOI: 10.1074/jbc.m303470200

PubMed ID: 15107404

Title: Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity.

PubMed ID: 15107404

DOI: 10.1101/gad.1183304

PubMed ID: 16360038

Title: Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

PubMed ID: 16360038

DOI: 10.1016/j.cell.2005.09.044

PubMed ID: 17671431

Title: LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes.

PubMed ID: 17671431

DOI: 10.4161/cc.6.15.4512

PubMed ID: 17531812

Title: Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence.

PubMed ID: 17531812

DOI: 10.1016/j.molcel.2007.04.015

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 22002537

Title: Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence.

PubMed ID: 22002537

DOI: 10.1038/emboj.2011.370

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10090723

Title: Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP.

PubMed ID: 10090723

DOI: 10.1101/gad.13.6.666

PubMed ID: 10679953

Title: Various AGC repeat numbers in the coding region of the human transcription factor gene E2F-4.

PubMed ID: 10679953

DOI: 10.1002/(sici)1098-1004(200003)15:3<296::aid-humu18>3.0.co;2-x

Sequence Information:

  • Length: 413
  • Mass: 43960
  • Checksum: BAAC95DE1B7E0832
  • Sequence:
    • MAEAGPQAPP PPGTPSRHEK SLGLLTTKFV SLLQEAKDGV LDLKLAADTL AVRQKRRIYD 
ITNVLEGIGL IEKKSKNSIQ WKGVGPGCNT REIADKLIEL KAEIEELQQR EQELDQHKVW 
VQQSIRNVTE DVQNSCLAYV THEDICRCFA GDTLLAIRAP SGTSLEVPIP EGLNGQKKYQ 
IHLKSVSGPI EVLLVNKEAW SSPPVAVPVP PPEDLLQSPS AVSTPPPLPK PALAQSQEAS 
RPNSPQLTPT AVPGSAEVQG MAGPAAEITV SGGPGTDSKD SGELSSLPLG PTTLDTRPLQ 
SSALLDSSSS SSSSSSSSSN SNSSSSSGPN PSTSFEPIKA DPTGVLELPK ELSEIFDPTR 
ECMSSELLEE LMSSEVFAPL LRLSPPPGDH DYIYNLDESE GVCDLFDVPV LNL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.