Details for: EIF4G2

Gene ID: 1982

Symbol: EIF4G2

Ensembl ID: ENSG00000110321

Description: eukaryotic translation initiation factor 4 gamma 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 710.2757
    Cell Significance Index: -110.4800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 461.6718
    Cell Significance Index: -117.1000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 308.2431
    Cell Significance Index: -126.9800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 267.7492
    Cell Significance Index: -108.7800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 267.1975
    Cell Significance Index: -126.1500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 239.4703
    Cell Significance Index: -123.1800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 188.5631
    Cell Significance Index: -126.5300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 115.2928
    Cell Significance Index: -110.0800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 99.6224
    Cell Significance Index: -122.8300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 37.3219
    Cell Significance Index: -99.9800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 32.9773
    Cell Significance Index: -130.1300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 31.0179
    Cell Significance Index: -95.2700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 20.0312
    Cell Significance Index: -43.8400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 3.9806
    Cell Significance Index: 104.6700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 3.9674
    Cell Significance Index: 206.6600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.9252
    Cell Significance Index: 106.8400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 3.6209
    Cell Significance Index: 445.2300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 3.3337
    Cell Significance Index: 600.9700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.1267
    Cell Significance Index: 146.9500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.9519
    Cell Significance Index: 78.8200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 2.4523
    Cell Significance Index: 51.3300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.3865
    Cell Significance Index: 111.2700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.2881
    Cell Significance Index: 147.6200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.2757
    Cell Significance Index: 65.2400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.2478
    Cell Significance Index: 78.1100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.1854
    Cell Significance Index: 257.7300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.1840
    Cell Significance Index: 299.9300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.1694
    Cell Significance Index: 278.1100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.1309
    Cell Significance Index: 1163.7100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 2.0499
    Cell Significance Index: 906.2900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.9298
    Cell Significance Index: 87.4700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.7833
    Cell Significance Index: 132.9100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.7521
    Cell Significance Index: 50.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.5935
    Cell Significance Index: 82.7800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.4552
    Cell Significance Index: 188.0100
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.3608
    Cell Significance Index: 31.4400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2848
    Cell Significance Index: 254.9700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2281
    Cell Significance Index: 133.5800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.1481
    Cell Significance Index: 21.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0120
    Cell Significance Index: 203.0200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.9365
    Cell Significance Index: 66.2300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.8769
    Cell Significance Index: 8.0800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.8580
    Cell Significance Index: 45.0500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.7804
    Cell Significance Index: 13.7900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.7077
    Cell Significance Index: 8.0400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6272
    Cell Significance Index: 38.5500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5677
    Cell Significance Index: 203.6300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.5154
    Cell Significance Index: 58.8300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4934
    Cell Significance Index: 84.2500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4618
    Cell Significance Index: 45.6800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4249
    Cell Significance Index: 383.6600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1288
    Cell Significance Index: 24.5100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1099
    Cell Significance Index: 3.8600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0857
    Cell Significance Index: 1.4400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0786
    Cell Significance Index: 59.4900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0427
    Cell Significance Index: 31.3300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0317
    Cell Significance Index: 1.7800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0154
    Cell Significance Index: -29.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0393
    Cell Significance Index: -29.1000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0611
    Cell Significance Index: -112.6300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0658
    Cell Significance Index: -41.1000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0679
    Cell Significance Index: -104.4900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0879
    Cell Significance Index: -55.8100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0884
    Cell Significance Index: -120.2500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0920
    Cell Significance Index: -63.6400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1066
    Cell Significance Index: -10.8900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1589
    Cell Significance Index: -89.6300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1615
    Cell Significance Index: -73.3200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.1906
    Cell Significance Index: -31.0100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2140
    Cell Significance Index: -16.4300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2226
    Cell Significance Index: -7.1300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2295
    Cell Significance Index: -6.7400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2325
    Cell Significance Index: -48.9700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2773
    Cell Significance Index: -7.7500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.3541
    Cell Significance Index: -3.8500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3749
    Cell Significance Index: -107.8700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.4428
    Cell Significance Index: -2.7200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4555
    Cell Significance Index: -28.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5163
    Cell Significance Index: -59.1500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5390
    Cell Significance Index: -6.4300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5456
    Cell Significance Index: -11.6200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.5612
    Cell Significance Index: -81.5700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6853
    Cell Significance Index: -9.3500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.7085
    Cell Significance Index: -82.5700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.8733
    Cell Significance Index: -52.4300
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.8827
    Cell Significance Index: -11.3100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.0087
    Cell Significance Index: -79.8900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.0698
    Cell Significance Index: -27.3300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.0833
    Cell Significance Index: -23.4700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.1746
    Cell Significance Index: -78.9800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.2132
    Cell Significance Index: -7.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.2276
    Cell Significance Index: -127.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.5592
    Cell Significance Index: -41.7800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.9423
    Cell Significance Index: -119.0800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.9623
    Cell Significance Index: -47.0600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.9676
    Cell Significance Index: -49.1900
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -2.1580
    Cell Significance Index: -17.2300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -2.2130
    Cell Significance Index: -97.8900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -2.2974
    Cell Significance Index: -39.3700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -2.4459
    Cell Significance Index: -65.4300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subunit of the eIF4F complex:** EIF4G2 is a subunit of the eIF4F complex, which is responsible for recruiting ribosomes to mRNA, facilitating translation initiation. 2. **Antiviral mechanism:** EIF4G2 is involved in antiviral mechanisms, particularly in the context of interferon-stimulated genes (ISGs). 3. **Immune regulation:** EIF4G2 is expressed in immune cells, such as IgG plasmablasts and myeloid leukocytes, and is involved in immune responses. 4. **Cell growth and development:** EIF4G2 is involved in promoting cell growth and development, as evidenced by its expression in skeletal muscle satellite stem cells and GABAergic neurons. 5. **Widespread expression:** EIF4G2 is expressed in various cell types, including thyroid follicular cells, lung endothelial cells, and chromaffin cells. **Pathways and Functions:** 1. **Eukaryotic translation initiation:** EIF4G2 facilitates the recruitment of ribosomes to mRNA, promoting translation initiation. 2. **Antiviral mechanism:** EIF4G2 is involved in antiviral mechanisms, particularly in the context of ISGs. 3. **Immune regulation:** EIF4G2 is involved in immune responses, including the regulation of cytokine signaling and the positive regulation of dendritic spine development. 4. **Cell growth and development:** EIF4G2 promotes cell growth and development, as evidenced by its expression in skeletal muscle satellite stem cells and GABAergic neurons. 5. **Regulation of cell cycle:** EIF4G2 is involved in regulating the cell cycle, particularly in the context of positive regulation of cell growth. **Clinical Significance:** 1. **Cancer:** Alterations in EIF4G2 expression have been implicated in various cancers, including thyroid cancer and lung cancer. 2. **Neurological disorders:** EIF4G2 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Immune disorders:** EIF4G2 has been implicated in immune disorders, such as autoimmune diseases and immunodeficiency disorders. 4. **Viral infections:** EIF4G2 has been implicated in viral infections, including HIV and influenza. In conclusion, EIF4G2 is a multifaceted gene that plays a crucial role in eukaryotic translation initiation, immune regulation, and cell growth and development. Its widespread expression across different cell types highlights its importance in various biological processes, and its involvement in various diseases underscores its potential as a therapeutic target. Further research is needed to fully elucidate the mechanisms by which EIF4G2 regulates these processes and to explore its therapeutic potential.

Genular Protein ID: 102744991

Symbol: IF4G2_HUMAN

Name: Eukaryotic translation initiation factor 4 gamma 2

UniProtKB Accession Codes:

P78344 O60877 P78404 Q0VH00 Q0VH01 Q2NKW9 Q49A79 Q53EU1 Q58EZ2 Q8NI71 Q96C16

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9049310

Title: A new translational regulator with homology to eukaryotic translation initiation factor 4G.

PubMed ID: 9049310

DOI: 10.1093/emboj/16.4.817

PubMed ID: 9030685

Title: A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme.

PubMed ID: 9030685

DOI: 10.1101/gad.11.3.321

PubMed ID: 9032289

Title: DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death.

PubMed ID: 9032289

DOI: 10.1128/mcb.17.3.1615

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 9878069

Title: Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.

PubMed ID: 9878069

DOI: 10.1093/emboj/18.1.270

PubMed ID: 11511540

Title: Suppression of cap-dependent translation in mitosis.

PubMed ID: 11511540

DOI: 10.1101/gad.889201

PubMed ID: 11943866

Title: The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins.

PubMed ID: 11943866

DOI: 10.1073/pnas.082102499

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 17984221

Title: Proline-rich transcript in brain protein induces stress granule formation.

PubMed ID: 17984221

DOI: 10.1128/mcb.01226-07

PubMed ID: 18025107

Title: SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein.

PubMed ID: 18025107

DOI: 10.1128/mcb.01500-07

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 907
  • Mass: 102362
  • Checksum: 4EF050B5EEA4DF91
  • Sequence:
    • MESAIAEGGA SRFSASSGGG GSRGAPQHYP KTAGNSEFLG KTPGQNAQKW IPARSTRRDD 
NSAANNSANE KERHDAIFRK VRGILNKLTP EKFDKLCLEL LNVGVESKLI LKGVILLIVD 
KALEEPKYSS LYAQLCLRLA EDAPNFDGPA AEGQPGQKQS TTFRRLLISK LQDEFENRTR 
NVDVYDKREN PLLPEEEEQR AIAKIKMLGN IKFIGELGKL DLIHESILHK CIKTLLEKKK 
RVQLKDMGED LECLCQIMRT VGPRLDHERA KSLMDQYFAR MCSLMLSKEL PARIRFLLQD 
TVELREHHWV PRKAFLDNGP KTINQIRQDA VKDLGVFIPA PMAQGMRSDF FLEGPFMPPR 
MKMDRDPLGG LADMFGQMPG SGIGTGPGVI QDRFSPTMGR HRSNQLFNGH GGHIMPPTQS 
QFGEMGGKFM KSQGLSQLYH NQSQGLLSQL QGQSKDMPPR FSKKGQLNAD EISLRPAQSF 
LMNKNQVPKL QPQITMIPPS AQPPRTQTPP LGQTPQLGLK TNPPLIQEKP AKTSKKPPPS 
KEELLKLTET VVTEYLNSGN ANEAVNGVRE MRAPKHFLPE MLSKVIILSL DRSDEDKEKA 
SSLISLLKQE GIATSDNFMQ AFLNVLDQCP KLEVDIPLVK SYLAQFAARA IISELVSISE 
LAQPLESGTH FPLFLLCLQQ LAKLQDREWL TELFQQSKVN MQKMLPEIDQ NKDRMLEILE 
GKGLSFLFPL LKLEKELLKQ IKLDPSPQTI YKWIKDNISP KLHVDKGFVN ILMTSFLQYI 
SSEVNPPSDE TDSSSAPSKE QLEQEKQLLL SFKPVMQKFL HDHVDLQVSA LYALQVHCYN 
SNFPKGMLLR FFVHFYDMEI IEEEAFLAWK EDITQEFPGK GKALFQVNQW LTWLETAEEE 
ESEEEAD

Genular Protein ID: 1868839823

Symbol: Q2TU89_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q2TU89

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 GO 3 Gene3D 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 701
  • Mass: 79614
  • Checksum: 08C279495DD0FC21
  • Sequence:
    • MLGNIKFIGE LGKLDLIHES ILHKCIKTLL EKKKRVQLKD MGEDLECLCQ IMRTVGPRLD 
HERAKSLMDQ YFARMCSLML SKELPARIRF LLQDTVELRE HHWVPRKAFL DNGPKTINQI 
RQDAVKDLGV FIPAPMAQGM RSDFFLEGPF MPPRMKMDRD PLGGLADMFG QMPGSGIGTG 
PGVIQDRFSP TMGRHRSNQL FNGHGGHIMP PTQSQFGEMG GKFMKSQGLS QLYHNQSQGL 
LSQLQGQSKD MPPRFSKKGQ LNADEISLRP AQSFLMNKNQ VPKLQPQITM IPPSAQPPRT 
QTPPLGQTPQ LGLKTNPPLI QEKPAKTSKK PPPSKEELLK LTETVVTEYL NSGNANEAVN 
GVREMRAPKH FLPEMLSKVI ILSLDRSDED KEKASSLISL LKQEGIATSD NFMQAFLNVL 
DQCPKLEVDI PLVKSYLAQF AARAIISELV SISELAQPLE SGTHFPLFLL CLQQLAKLQD 
REWLTELFQQ SKVNMQKMLP EIDQNKDRML EILEGKGLSF LFPLLKLEKE LLKQIKLDPS 
PQTIYKWIKD NISPKLHVDK GFVNILMTSF LQYISSEVNP PSDETDSSSA PSKEQLEQEK 
QLLLSFKPVM QKFLHDHVDL QVSALYALQV HCYNSNFPKG MLLRFFVHFY DMEIIEEEAF 
LAWKEDITQE FPGKGKALFQ VNQWLTWLET AEEEESEEEA D

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.