Details for: ETS1

Gene ID: 2113

Symbol: ETS1

Ensembl ID: ENSG00000134954

Description: ETS proto-oncogene 1, transcription factor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 219.9039
    Cell Significance Index: -34.2100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 134.5196
    Cell Significance Index: -34.1200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 86.3702
    Cell Significance Index: -35.5800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 84.4047
    Cell Significance Index: -34.2900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 37.4027
    Cell Significance Index: -35.7100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.7646
    Cell Significance Index: -34.2300
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 22.4366
    Cell Significance Index: 60.1100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.9464
    Cell Significance Index: -34.9000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.7737
    Cell Significance Index: -31.5400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.9111
    Cell Significance Index: -27.3700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.7632
    Cell Significance Index: -34.5800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 5.6853
    Cell Significance Index: 296.1400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 5.0916
    Cell Significance Index: 73.2300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.2872
    Cell Significance Index: 94.2300
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 3.2665
    Cell Significance Index: 23.4600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.7172
    Cell Significance Index: 211.1400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.6715
    Cell Significance Index: 49.0900
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.5463
    Cell Significance Index: 15.5100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.3248
    Cell Significance Index: 156.2300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.0266
    Cell Significance Index: 185.0600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0099
    Cell Significance Index: 164.2600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.9031
    Cell Significance Index: 10.2600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8465
    Cell Significance Index: 92.0800
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.8149
    Cell Significance Index: 8.4400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.7917
    Cell Significance Index: 37.2100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.5462
    Cell Significance Index: 3.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4278
    Cell Significance Index: 49.8600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.4224
    Cell Significance Index: 7.4700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4175
    Cell Significance Index: 28.8700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3704
    Cell Significance Index: 7.2300
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.3331
    Cell Significance Index: 2.6300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3059
    Cell Significance Index: 42.0100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2930
    Cell Significance Index: 7.9800
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.2840
    Cell Significance Index: 2.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2285
    Cell Significance Index: 22.6000
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 0.1516
    Cell Significance Index: 0.7000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1260
    Cell Significance Index: 3.6300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0732
    Cell Significance Index: 3.7000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0641
    Cell Significance Index: 8.2200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0532
    Cell Significance Index: 3.2700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0216
    Cell Significance Index: 0.9800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0158
    Cell Significance Index: 3.0000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0135
    Cell Significance Index: 1.0300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0055
    Cell Significance Index: 3.0300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0040
    Cell Significance Index: 0.2100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0061
    Cell Significance Index: -11.5400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0063
    Cell Significance Index: -4.3700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0091
    Cell Significance Index: -14.0600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0123
    Cell Significance Index: -7.6700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0133
    Cell Significance Index: -1.7200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0142
    Cell Significance Index: -10.5400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0151
    Cell Significance Index: -27.8700
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.0195
    Cell Significance Index: -0.1400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0220
    Cell Significance Index: -9.7200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0259
    Cell Significance Index: -35.2100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0291
    Cell Significance Index: -13.2000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0296
    Cell Significance Index: -5.8800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0303
    Cell Significance Index: -17.0600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0392
    Cell Significance Index: -29.7000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0415
    Cell Significance Index: -6.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0427
    Cell Significance Index: -27.1000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0445
    Cell Significance Index: -2.8700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0480
    Cell Significance Index: -9.6200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0483
    Cell Significance Index: -8.2500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0502
    Cell Significance Index: -36.8200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0838
    Cell Significance Index: -30.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0888
    Cell Significance Index: -18.7000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1031
    Cell Significance Index: -29.6600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1153
    Cell Significance Index: -13.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1387
    Cell Significance Index: -15.8900
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: -0.2343
    Cell Significance Index: -0.8200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2428
    Cell Significance Index: -24.8000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2442
    Cell Significance Index: -5.2000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3067
    Cell Significance Index: -31.9400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.3225
    Cell Significance Index: -5.5600
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -0.3631
    Cell Significance Index: -1.9800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3702
    Cell Significance Index: -26.1800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3803
    Cell Significance Index: -7.8900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3964
    Cell Significance Index: -18.4800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4453
    Cell Significance Index: -33.1900
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.4656
    Cell Significance Index: -4.8300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4757
    Cell Significance Index: -37.6800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4811
    Cell Significance Index: -15.4100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5016
    Cell Significance Index: -30.7500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5170
    Cell Significance Index: -34.7700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5240
    Cell Significance Index: -8.7700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.5607
    Cell Significance Index: -8.0300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5647
    Cell Significance Index: -35.5900
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.5679
    Cell Significance Index: -4.7700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.6053
    Cell Significance Index: -15.1300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6346
    Cell Significance Index: -35.6100
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.6697
    Cell Significance Index: -9.1700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6792
    Cell Significance Index: -35.6600
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.6880
    Cell Significance Index: -5.6100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7787
    Cell Significance Index: -20.8300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7848
    Cell Significance Index: -34.7200
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.7947
    Cell Significance Index: -12.7500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.8138
    Cell Significance Index: -13.4100
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.8320
    Cell Significance Index: -8.8400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.8570
    Cell Significance Index: -18.1900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transcription Factor**: ETS1 is a transcription factor that regulates the expression of genes by binding to specific DNA sequences. 2. **Proto-Oncogene**: ETS1 is classified as a proto-oncogene, which means it has the potential to become an oncogene if mutated or overexpressed. 3. **Cellular Specificity**: ETS1 is expressed in various cell types, including CD8-positive T cells, lung endothelial cells, and fibroblasts of the mammary gland. 4. **Regulatory Functions**: ETS1 regulates angiogenesis, inflammation, and immune response by controlling the expression of genes involved in these processes. **Pathways and Functions:** 1. **Angiogenesis**: ETS1 regulates angiogenesis by controlling the expression of genes involved in endothelial cell migration and tube formation. 2. **Immune Response**: ETS1 is involved in regulating the expression of genes involved in immune cell development and function, including T cell activation and cytokine production. 3. **Cell Differentiation**: ETS1 regulates cell differentiation by controlling the expression of genes involved in the development of specific cell types, such as T cells and endothelial cells. 4. **Chromatin Remodeling**: ETS1 regulates chromatin remodeling by controlling the expression of genes involved in chromatin structure and function. **Clinical Significance:** The ETS1 gene has been implicated in various diseases, including: 1. **Cancer**: ETS1 has been found to be overexpressed in several types of cancer, including lung, breast, and prostate cancer. 2. **Autoimmune Diseases**: ETS1 has been implicated in the regulation of immune responses and has been found to be overexpressed in autoimmune diseases such as rheumatoid arthritis and multiple sclerosis. 3. **Infectious Diseases**: ETS1 has been found to be involved in the regulation of immune responses to infectious diseases, including HIV and tuberculosis. In conclusion, the ETS1 gene is a critical regulator of cellular processes and immune response, and its dysregulation has been implicated in various diseases. Further research is needed to fully understand the functions of ETS1 and its role in human disease. **References:** * [Insert references here] Note: As an expert immunologist, I have summarized the key characteristics, pathways, and functions of the ETS1 gene, and discussed its clinical significance. However, a full review of the literature is necessary to provide a comprehensive understanding of the gene's role in human disease.

Genular Protein ID: 1786107031

Symbol: ETS1_HUMAN

Name: Protein C-ets-1

UniProtKB Accession Codes:

P14921 A9UL17 F5GYX9 Q14278 Q16080 Q6N087 Q96AC5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CORUM 1 CPTAC 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 13 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 35 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 21 PDBsum 21 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3060801

Title: Structure, expression and alternative splicing of the human c-ets-1 proto-oncogene.

PubMed ID: 3060801

PubMed ID: 2847145

Title: Mammalian ets-1 and ets-2 genes encode highly conserved proteins.

PubMed ID: 2847145

DOI: 10.1073/pnas.85.21.7862

PubMed ID: 19377509

Title: Ets-1 p27: a novel Ets-1 isoform with dominant-negative effects on the transcriptional properties and the subcellular localization of Ets-1 p51.

PubMed ID: 19377509

DOI: 10.1038/onc.2009.72

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1614856

Title: Serum, AP-1 and Ets-1 stimulate the human ets-1 promoter.

PubMed ID: 1614856

DOI: 10.1093/nar/20.11.2699

PubMed ID: 8231246

Title: Quantitative and qualitative variation of ETS-1 transcripts in hematologic malignancies.

PubMed ID: 8231246

PubMed ID: 2997781

Title: The ets sequence from the transforming gene of avian erythroblastosis virus, E26, has unique domains on human chromosomes 11 and 21: both loci are transcriptionally active.

PubMed ID: 2997781

DOI: 10.1073/pnas.82.21.7294

PubMed ID: 9333025

Title: Modulation of ETS-1 transcriptional activity by huUBC9, a ubiquitin-conjugating enzyme.

PubMed ID: 9333025

DOI: 10.1038/sj.onc.1201301

PubMed ID: 10698492

Title: EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes.

PubMed ID: 10698492

DOI: 10.1038/sj.onc.1203385

PubMed ID: 11909962

Title: Sp100 interacts with ETS-1 and stimulates its transcriptional activity.

PubMed ID: 11909962

DOI: 10.1128/mcb.22.8.2687-2702.2002

PubMed ID: 15247905

Title: SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion.

PubMed ID: 15247905

DOI: 10.1038/sj.onc.1207891

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 15592518

Title: SP100 inhibits ETS1 activity in primary endothelial cells.

PubMed ID: 15592518

DOI: 10.1038/sj.onc.1208245

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20378371

Title: Transcription factor Ets-1 in cytokine and chemokine gene regulation.

PubMed ID: 20378371

DOI: 10.1016/j.cyto.2010.03.006

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 8521493

Title: The solution structure of the human ETS1-DNA complex reveals a novel mode of binding and true side chain intercalation.

PubMed ID: 8521493

DOI: 10.1016/0092-8674(95)90189-2

PubMed ID: 18566588

Title: Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization.

PubMed ID: 18566588

DOI: 10.1038/emboj.2008.117

Sequence Information:

  • Length: 441
  • Mass: 50408
  • Checksum: 3B66BCC464B393FB
  • Sequence:
    • MKAAVDLKPT LTIIKTEKVD LELFPSPDME CADVPLLTPS SKEMMSQALK ATFSGFTKEQ 
QRLGIPKDPR QWTETHVRDW VMWAVNEFSL KGVDFQKFCM NGAALCALGK DCFLELAPDF 
VGDILWEHLE ILQKEDVKPY QVNGVNPAYP ESRYTSDYFI SYGIEHAQCV PPSEFSEPSF 
ITESYQTLHP ISSEELLSLK YENDYPSVIL RDPLQTDTLQ NDYFAIKQEV VTPDNMCMGR 
TSRGKLGGQD SFESIESYDS CDRLTQSWSS QSSFNSLQRV PSYDSFDSED YPAALPNHKP 
KGTFKDYVRD RADLNKDKPV IPAAALAGYT GSGPIQLWQF LLELLTDKSC QSFISWTGDG 
WEFKLSDPDE VARRWGKRKN KPKMNYEKLS RGLRYYYDKN IIHKTAGKRY VYRFVCDLQS 
LLGYTPEELH AMLDVKPDAD E

Genular Protein ID: 1132916760

Symbol: B4DW78_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DW78

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 300
  • Mass: 34054
  • Checksum: 4B55706D38D9B3DE
  • Sequence:
    • MKAAVDLKPT LTIIKTEKVD LELFPSPDME CADVPLLTPS SKEMMSQALK ATFSGFTKEQ 
QRLGIPKDPR QWTETHVRDW VMWAVNEFSL KGVDFQKFCM NGAALCALGK DCFLELAPDF 
VGDILWEHLE ILQKEDVKPY QVNGVNPAYP ESRYTSDYFI SYGIEHAQCV PPSEFSEPSF 
ITESYQTLHP ISSEELLSLK YENDYPSVIL RDPLQTDTLQ NDYFAIKQEV VTPDNMCMGR 
TSRGKLGGQD SFESIESYDS CDRLTQSWSS QSSFNSLQRV PSYDSFDSED YPAALPNHKP

Genular Protein ID: 3891433009

Symbol: A8K725_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K725

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 9 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 1 PROSITE 6 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 RuleBase 1 SMART 2 SMR 1 SUPFAM 2

Sequence Information:

  • Length: 441
  • Mass: 50321
  • Checksum: 0EE363BE4AA3DC6F
  • Sequence:
    • MKAAVDLKPT LTIIKTEKVD LELFPSPDME CADVPLLTPS SKEMMSQALK ATFSGFTKEQ 
QRLGIPKDPR QWTETHVRDW VTWAVNEFSL KGVDFQKFCM NGAALCALGK DCFLELAPDF 
VGDILWEHLE ILQKEDVKPY QVNGVNPAYP ESRYTSDYFI SYGIEHAQCV PPSEFSEPSF 
ITESYQTLHP ISSEELLSLK YENDYPSVIL RDPLQTDTLQ NDYFAIKQEV VTPDNMCMGR 
TSRGKLGGQD SFESIESYDS CDRLTQSWSS QSSFNSLQRV PSYDSFDSED YPAALPNHKP 
KGTFKDYVRD RADLNKDKPV IPAAALAGYT GSGPIQLWQF LLELLTDKSC QSFISWTGDG 
WEFKLSDPDE VARRWGKRKN KPKMNYEKLS RGLRYYYDKD IIHKTAGKRY VYRFVCDLQS 
LLGYTPEELH AMLGVKPDAD E

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.