Details for: ETV6
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 4.63
Marker Score: 3,213 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 4.47
Marker Score: 3,580 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 4.24
Marker Score: 1,531 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 3.75
Marker Score: 3,330 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 3.34
Marker Score: 7,322 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 3.05
Marker Score: 1,517 - Cell Name: contractile cell (CL0000183)
Fold Change: 3
Marker Score: 1,623 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 2.99
Marker Score: 861 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 2.76
Marker Score: 2,386 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.7
Marker Score: 1,575 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.41
Marker Score: 4,644 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.37
Marker Score: 2,687 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.36
Marker Score: 747 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.26
Marker Score: 1,347 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.25
Marker Score: 39,887 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 2.23
Marker Score: 3,236 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.22
Marker Score: 81,919 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 2.19
Marker Score: 1,801 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.18
Marker Score: 46,495 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.17
Marker Score: 2,393 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.02
Marker Score: 2,715 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.99
Marker Score: 44,390 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.97
Marker Score: 1,096 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.96
Marker Score: 1,865 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.9
Marker Score: 484 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.84
Marker Score: 861 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.84
Marker Score: 1,209 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 1.82
Marker Score: 890 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.82
Marker Score: 569 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.79
Marker Score: 523 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 1.78
Marker Score: 447 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.78
Marker Score: 1,909 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.77
Marker Score: 3,609 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.72
Marker Score: 1,006 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.72
Marker Score: 554 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.72
Marker Score: 7,180 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.7
Marker Score: 3,017 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.7
Marker Score: 2,055 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.7
Marker Score: 33,814 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.69
Marker Score: 1,301 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.69
Marker Score: 14,489 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.67
Marker Score: 26,767 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 1.67
Marker Score: 822 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.66
Marker Score: 15,649 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.64
Marker Score: 922 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.64
Marker Score: 12,558 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.64
Marker Score: 1,883 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.6
Marker Score: 605 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.59
Marker Score: 15,128 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.59
Marker Score: 1,716 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.58
Marker Score: 2,327 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.56
Marker Score: 1,351 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.56
Marker Score: 3,549 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.55
Marker Score: 529 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.54
Marker Score: 94,886 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.54
Marker Score: 559 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.52
Marker Score: 6,318 - Cell Name: megakaryocyte progenitor cell (CL0000553)
Fold Change: 1.47
Marker Score: 411 - Cell Name: microglial cell (CL0000129)
Fold Change: 1.47
Marker Score: 2,671 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.46
Marker Score: 2,253 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 1.46
Marker Score: 1,055 - Cell Name: thymocyte (CL0000893)
Fold Change: 1.45
Marker Score: 1,516 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.44
Marker Score: 701 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 1.43
Marker Score: 453 - Cell Name: club cell (CL0000158)
Fold Change: 1.43
Marker Score: 1,666 - Cell Name: secretory cell (CL0000151)
Fold Change: 1.42
Marker Score: 2,601 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.42
Marker Score: 1,756 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.41
Marker Score: 285 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.41
Marker Score: 958 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.4
Marker Score: 3,301 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.39
Marker Score: 520 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1.36
Marker Score: 392 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.35
Marker Score: 1,639 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.35
Marker Score: 954 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.35
Marker Score: 75,509 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 1.35
Marker Score: 472 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 1.35
Marker Score: 5,619 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.34
Marker Score: 1,672 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.34
Marker Score: 896 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 1.34
Marker Score: 7,008 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.33
Marker Score: 1,878 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.31
Marker Score: 20,491 - Cell Name: ciliated cell (CL0000064)
Fold Change: 1.31
Marker Score: 4,494 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.28
Marker Score: 9,521 - Cell Name: plasmacytoid dendritic cell, human (CL0001058)
Fold Change: 1.27
Marker Score: 335 - Cell Name: podocyte (CL0000653)
Fold Change: 1.27
Marker Score: 469 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.26
Marker Score: 4,661 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.25
Marker Score: 2,106 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.25
Marker Score: 750 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.24
Marker Score: 2,930 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.23
Marker Score: 18,408 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 1.23
Marker Score: 848 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.22
Marker Score: 12,398 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 1.22
Marker Score: 10,609 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 1.22
Marker Score: 445 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 1.21
Marker Score: 333 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 1.21
Marker Score: 822 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.2
Marker Score: 485 - Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 1.2
Marker Score: 2,274 - Cell Name: Schwann cell (CL0002573)
Fold Change: 1.19
Marker Score: 414
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1964543807
Symbol: ETV6_HUMAN
Name: Transcription factor ETV6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8168137
Title: Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation.
PubMed ID: 8168137
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8743990
Title: Genomic organization of TEL: the human ETS-variant gene 6.
PubMed ID: 8743990
DOI: 10.1101/gr.6.5.404
PubMed ID: 17344859
Title: Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
PubMed ID: 17344859
DOI: 10.1038/nature05690
PubMed ID: 7731705
Title: Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11.
PubMed ID: 7731705
PubMed ID: 7761424
Title: Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.
PubMed ID: 7761424
PubMed ID: 7780150
Title: The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.
PubMed ID: 7780150
PubMed ID: 9326218
Title: Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia.
PubMed ID: 9326218
PubMed ID: 10502316
Title: Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).
PubMed ID: 10502316
DOI: 10.1002/(sici)1098-2264(199911)26:3<192::aid-gcc2>3.0.co;2-e
PubMed ID: 10477709
Title: Fusion of a novel gene, BTL, to ETV6 in acute myeloid leukemias with a t(4;12)(q11-q12;p13).
PubMed ID: 10477709
PubMed ID: 12435397
Title: Functional regulation of TEL by p38-induced phosphorylation.
PubMed ID: 12435397
PubMed ID: 12203785
Title: A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome.
PubMed ID: 12203785
DOI: 10.1002/gcc.10090
PubMed ID: 12181402
Title: Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta.
PubMed ID: 12181402
DOI: 10.1056/nejmoa020150
PubMed ID: 12588862
Title: The human L(3)MBT Polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).
PubMed ID: 12588862
PubMed ID: 12590135
Title: The histone deacetylase 9 gene encodes multiple protein isoforms.
PubMed ID: 12590135
PubMed ID: 15806161
Title: Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia.
PubMed ID: 15806161
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 25581430
Title: Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy.
PubMed ID: 25581430
DOI: 10.1038/ng.3177
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 452
- Mass: 53000
- Checksum: DEC45682ECADECBB
- Sequence:
MSETPAQCSI KQERISYTPP ESPVPSYASS TPLHVPVPRA LRMEEDSIRL PAHLRLQPIY WSRDDVAQWL KWAENEFSLR PIDSNTFEMN GKALLLLTKE DFRYRSPHSG DVLYELLQHI LKQRKPRILF SPFFHPGNSI HTQPEVILHQ NHEEDNCVQR TPRPSVDNVH HNPPTIELLH RSRSPITTNH RPSPDPEQRP LRSPLDNMIR RLSPAERAQG PRPHQENNHQ ESYPLSVSPM ENNHCPASSE SHPKPSSPRQ ESTRVIQLMP SPIMHPLILN PRHSVDFKQS RLSEDGLHRE GKPINLSHRE DLAYMNHIMV SVSPPEEHAM PIGRIADCRL LWDYVYQLLS DSRYENFIRW EDKESKIFRI VDPNGLARLW GNHKNRTNMT YEKMSRALRH YYKLNIIRKE PGQRLLFRFM KTPDEIMSGR TDRLEHLESQ ELDEQIYQED EC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.