Details for: EXTL2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 155.0353
Cell Significance Index: -24.1200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 84.8041
Cell Significance Index: -21.5100 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 57.3131
Cell Significance Index: -23.6100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 53.5878
Cell Significance Index: -25.3000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 50.2145
Cell Significance Index: -20.4000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 21.3775
Cell Significance Index: -20.4100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 20.1183
Cell Significance Index: -24.8100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.1494
Cell Significance Index: -24.5100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.3760
Cell Significance Index: -25.1600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.6184
Cell Significance Index: 70.1600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 2.5819
Cell Significance Index: 43.2100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.3748
Cell Significance Index: 63.4100 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.4054
Cell Significance Index: 8.7000 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 1.2770
Cell Significance Index: 26.7300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.0682
Cell Significance Index: 37.1200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.0488
Cell Significance Index: 103.7500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.0302
Cell Significance Index: 45.5700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.9986
Cell Significance Index: 200.3200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.9199
Cell Significance Index: 117.9300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7867
Cell Significance Index: 710.3500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6334
Cell Significance Index: 125.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.5967
Cell Significance Index: 81.9500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5602
Cell Significance Index: 91.1200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5289
Cell Significance Index: 57.5300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.5107
Cell Significance Index: 19.3400 - Cell Name: theca cell (CL0000503)
Fold Change: 0.5106
Cell Significance Index: 3.0000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4543
Cell Significance Index: 162.9600 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.4537
Cell Significance Index: 11.9300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.4533
Cell Significance Index: 28.5700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.4114
Cell Significance Index: 24.7000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.3357
Cell Significance Index: 18.8400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.2792
Cell Significance Index: 32.5400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2460
Cell Significance Index: 11.1500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.2330
Cell Significance Index: 127.2200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2297
Cell Significance Index: 43.7100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2230
Cell Significance Index: 15.4300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2184
Cell Significance Index: 39.3700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2151
Cell Significance Index: 11.1800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2133
Cell Significance Index: 94.3000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1989
Cell Significance Index: 5.7300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.1847
Cell Significance Index: 9.6200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1648
Cell Significance Index: 10.1300 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.1601
Cell Significance Index: 2.0500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1339
Cell Significance Index: 92.6400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1269
Cell Significance Index: 15.6000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1240
Cell Significance Index: 3.1000 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.0717
Cell Significance Index: 0.7800 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.0474
Cell Significance Index: 1.2100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0347
Cell Significance Index: 1.8200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0160
Cell Significance Index: 30.0800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0126
Cell Significance Index: 8.0300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0079
Cell Significance Index: 14.5100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0058
Cell Significance Index: 8.9400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0057
Cell Significance Index: 0.4400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0040
Cell Significance Index: 0.2800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.0037
Cell Significance Index: 0.0500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0083
Cell Significance Index: -11.3400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0085
Cell Significance Index: -6.2300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0242
Cell Significance Index: -18.3000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0256
Cell Significance Index: -11.6300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0280
Cell Significance Index: -4.0700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0302
Cell Significance Index: -1.0600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0319
Cell Significance Index: -23.6200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0432
Cell Significance Index: -24.3900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0465
Cell Significance Index: -29.0300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0683
Cell Significance Index: -19.6400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0722
Cell Significance Index: -7.3800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0761
Cell Significance Index: -3.5500 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.0838
Cell Significance Index: -1.3300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0869
Cell Significance Index: -14.8500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1118
Cell Significance Index: -3.1300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1269
Cell Significance Index: -16.4000 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1282
Cell Significance Index: -2.6600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1380
Cell Significance Index: -29.0700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1531
Cell Significance Index: -3.2500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1535
Cell Significance Index: -10.3200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1561
Cell Significance Index: -4.2500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1631
Cell Significance Index: -2.8000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1669
Cell Significance Index: -19.1200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1814
Cell Significance Index: -4.3500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1863
Cell Significance Index: -21.9700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1874
Cell Significance Index: -12.0900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1911
Cell Significance Index: -4.1400 - Cell Name: kidney cell (CL1000497)
Fold Change: -0.1916
Cell Significance Index: -1.5300 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.2076
Cell Significance Index: -2.4800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.2274
Cell Significance Index: -1.9100 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.2284
Cell Significance Index: -1.4300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2316
Cell Significance Index: -24.1100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2331
Cell Significance Index: -4.5500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2348
Cell Significance Index: -5.0000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2384
Cell Significance Index: -17.7700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2599
Cell Significance Index: -12.2200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2730
Cell Significance Index: -21.6200 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.3615
Cell Significance Index: -5.0700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3651
Cell Significance Index: -10.4200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3661
Cell Significance Index: -9.7900 - Cell Name: peg cell (CL4033014)
Fold Change: -0.3978
Cell Significance Index: -9.1900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4151
Cell Significance Index: -25.4500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.4268
Cell Significance Index: -12.2400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.4441
Cell Significance Index: -13.0800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2267400315
Symbol: EXTL2_HUMAN
Name: Exostosin-like 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9450183
Title: Identification and characterization of a novel member of the EXT gene family, EXTL2.
PubMed ID: 9450183
PubMed ID: 9473480
Title: Structure, chromosomal location, and expression profile of EXTR1 and EXTR2, new members of the multiple exostoses gene family.
PubMed ID: 9473480
PubMed ID: 10639137
Title: The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate.
PubMed ID: 10639137
PubMed ID: 10318803
Title: The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate.
PubMed ID: 10318803
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 330
- Mass: 37466
- Checksum: 6976BE7EC6F588C8
- Sequence:
MRCCHICKLP GRVMGIRVLR LSLVVILVLL LVAGALTALL PSVKEDKMLM LRREIKSQGK STMDSFTLIM QTYNRTDLLL KLLNHYQAVP NLHKVIVVWN NIGEKAPDEL WNSLGPHPIP VIFKQQTANR MRNRLQVFPE LETNAVLMVD DDTLISTPDL VFAFSVWQQF PDQIVGFVPR KHVSTSSGIY SYGSFEMQAP GSGNGDQYSM VLIGASFFNS KYLELFQRQP AAVHALIDDT QNCDDIAMNF IIAKHIGKTS GIFVKPVNMD NLEKETNSGY SGMWHRAEHA LQRSYCINKL VNIYDSMPLR YSNIMISQFG FPYANYKRKI
Genular Protein ID: 2983089596
Symbol: Q8N8F1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 329
- Mass: 37395
- Checksum: 7CE07064474BE340
- Sequence:
MRCCHICKLP GRVMGIRVLR LSLVVILVLL LVAGALTALL PSVKEDKMLM LRREIKSQGK STMDSFTLIM QTYNRTDLLL KLLNHYQAVP NLHKVIVVWN NIGEKAPDEL WNSLGPHPIP VIFKQQTANR MRNRLQVFPE LETNVLMVDD DTLISTPDLV FAFSVWQQFP DQIVGFVPRK HVSTSSGIYS YGSFEMQAPG SGNGDQYSMV LIGASFFNSK YLELFQRQPA AVHALIDDTQ NCDDIAMNFI IAKHIGKTSG IFVKPVNMDN LEKETNSGYS GMWHRAEHAL QRSYCINKLV NIYDSMPLRY SNIMISQFGF PYANYKRKI
Genular Protein ID: 1859259076
Symbol: F5GZK1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
Sequence Information:
- Length: 147
- Mass: 16751
- Checksum: 8E9DC29F7E68F006
- Sequence:
MRCCHICKLP GRVMGIRVLR LSLVVILVLL LVAGALTALL PSVKEDKMLM LRREIKSQGK STMDSFTLIM QTYNRTDLLL KLLNHYQAVP NLHKVIVVWN NIGEKAPDEL WNSLGPHPIP VIFKQQTANR MRNRLQVFPE LETNAIS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.