Details for: FANCC
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 147.4812
Cell Significance Index: -22.9400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 93.9212
Cell Significance Index: -23.8200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 46.7930
Cell Significance Index: -19.0100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 45.8144
Cell Significance Index: -21.6300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 19.9111
Cell Significance Index: -19.0100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 19.3194
Cell Significance Index: -23.8200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.1559
Cell Significance Index: -17.8500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.0725
Cell Significance Index: -23.9600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 3.1166
Cell Significance Index: 53.4100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.3728
Cell Significance Index: 133.1500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.1057
Cell Significance Index: 417.8900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 2.0756
Cell Significance Index: 301.7200 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 1.8220
Cell Significance Index: 18.3800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.6480
Cell Significance Index: 313.6200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.5694
Cell Significance Index: 43.8600 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.5276
Cell Significance Index: 13.5600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.4523
Cell Significance Index: 37.3300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.1521
Cell Significance Index: 88.4100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.9829
Cell Significance Index: 24.5700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.9648
Cell Significance Index: 193.5400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.9113
Cell Significance Index: 90.1500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8767
Cell Significance Index: 142.5800 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.8741
Cell Significance Index: 17.0600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.8550
Cell Significance Index: 37.8200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.7988
Cell Significance Index: 30.2500 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 0.7968
Cell Significance Index: 8.3000 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.7237
Cell Significance Index: 12.1900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5323
Cell Significance Index: 480.6400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5115
Cell Significance Index: 30.7100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5062
Cell Significance Index: 55.0600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4744
Cell Significance Index: 170.1600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.4328
Cell Significance Index: 26.6000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.4202
Cell Significance Index: 9.2000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4194
Cell Significance Index: 19.0100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.4182
Cell Significance Index: 643.7700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4076
Cell Significance Index: 8.8300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.3807
Cell Significance Index: 702.1000 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 0.3598
Cell Significance Index: 1.3600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.3325
Cell Significance Index: 17.3200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2464
Cell Significance Index: 463.9100 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.2366
Cell Significance Index: 1.4600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.2365
Cell Significance Index: 5.7700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2254
Cell Significance Index: 143.1600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2041
Cell Significance Index: 4.9000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1948
Cell Significance Index: 264.8200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.1878
Cell Significance Index: 4.0200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1636
Cell Significance Index: 19.0600 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.1634
Cell Significance Index: 2.3500 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 0.1457
Cell Significance Index: 1.8400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1229
Cell Significance Index: 8.5000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1079
Cell Significance Index: 3.7900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.1053
Cell Significance Index: 7.0800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1021
Cell Significance Index: 46.3500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0801
Cell Significance Index: 14.4400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0635
Cell Significance Index: 7.8100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0546
Cell Significance Index: 24.1500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.0420
Cell Significance Index: 4.3700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0344
Cell Significance Index: 0.9900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.0172
Cell Significance Index: 0.2300 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.0146
Cell Significance Index: 0.2100 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 0.0130
Cell Significance Index: 0.2100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0029
Cell Significance Index: 0.1900 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0006
Cell Significance Index: -0.3500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0208
Cell Significance Index: -15.4100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0227
Cell Significance Index: -0.4700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0252
Cell Significance Index: -18.5000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0281
Cell Significance Index: -21.3000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0317
Cell Significance Index: -17.8600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0377
Cell Significance Index: -23.5500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0389
Cell Significance Index: -6.6500 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0447
Cell Significance Index: -0.6600 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.0561
Cell Significance Index: -0.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0644
Cell Significance Index: -8.8400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0665
Cell Significance Index: -1.7800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0692
Cell Significance Index: -19.9200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0699
Cell Significance Index: -3.2600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0715
Cell Significance Index: -8.4300 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0909
Cell Significance Index: -11.6500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0930
Cell Significance Index: -1.9800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0994
Cell Significance Index: -20.9400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1060
Cell Significance Index: -4.9800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1205
Cell Significance Index: -13.8000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1244
Cell Significance Index: -12.7100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1407
Cell Significance Index: -18.1800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1503
Cell Significance Index: -7.8100 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1504
Cell Significance Index: -2.2200 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.1757
Cell Significance Index: -2.1000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1793
Cell Significance Index: -10.9900 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.2080
Cell Significance Index: -2.6300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2244
Cell Significance Index: -14.4800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2319
Cell Significance Index: -16.4000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2332
Cell Significance Index: -3.3400 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.2452
Cell Significance Index: -3.7300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2559
Cell Significance Index: -19.0700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2570
Cell Significance Index: -20.3600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2743
Cell Significance Index: -8.9800 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2761
Cell Significance Index: -4.1600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2794
Cell Significance Index: -8.9500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2991
Cell Significance Index: -9.5300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3155
Cell Significance Index: -5.2800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2050860821
Symbol: FANCC_HUMAN
Name: Fanconi anemia group C protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1574115
Title: Cloning of cDNAs for Fanconi's anaemia by functional complementation.
PubMed ID: 1574115
DOI: 10.1038/356763a0
PubMed ID: 1641028
PubMed ID: 8490620
Title: Characterisation of the exon structure of the Fanconi anaemia group C gene by vectorette PCR.
PubMed ID: 8490620
DOI: 10.1093/hmg/2.1.35
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7517562
Title: The Fanconi anemia polypeptide FACC is localized to the cytoplasm.
PubMed ID: 7517562
PubMed ID: 8058745
Title: Localization of Fanconi anemia C protein to the cytoplasm of mammalian cells.
PubMed ID: 8058745
PubMed ID: 9242535
Title: The Fanconi anemia polypeptide, FAC, binds to the cyclin-dependent kinase, cdc2.
PubMed ID: 9242535
PubMed ID: 10572087
Title: A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF.
PubMed ID: 10572087
PubMed ID: 11520787
Title: The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality.
PubMed ID: 11520787
PubMed ID: 12724401
Title: A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome.
PubMed ID: 12724401
PubMed ID: 15299030
Title: The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR).
PubMed ID: 15299030
PubMed ID: 15502827
Title: X-linked inheritance of Fanconi anemia complementation group B.
PubMed ID: 15502827
DOI: 10.1038/ng1458
PubMed ID: 16116422
Title: A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.
PubMed ID: 16116422
DOI: 10.1038/ng1626
PubMed ID: 22266823
Title: Regulation of Rev1 by the Fanconi anemia core complex.
PubMed ID: 22266823
DOI: 10.1038/nsmb.2222
PubMed ID: 8499901
Title: A Leu554-to-Pro substitution completely abolishes the functional complementing activity of the Fanconi anemia (FACC) protein.
PubMed ID: 8499901
DOI: 10.1093/hmg/2.2.123
PubMed ID: 8348157
Title: A common mutation in the FACC gene causes Fanconi anaemia in Ashkenazi Jews.
PubMed ID: 8348157
DOI: 10.1038/ng0693-202
PubMed ID: 8128956
Title: Mutation analysis of the Fanconi anemia gene FACC.
PubMed ID: 8128956
PubMed ID: 8844212
Title: Novel mutations and polymorphisms in the Fanconi anemia group C gene.
PubMed ID: 8844212
DOI: 10.1002/(sici)1098-1004(1996)8:2<140::aid-humu6>3.0.co;2-f
Sequence Information:
- Length: 558
- Mass: 63429
- Checksum: C9DDFFAC725D050C
- Sequence:
MAQDSVDLSC DYQFWMQKLS VWDQASTLET QQDTCLHVAQ FQEFLRKMYE ALKEMDSNTV IERFPTIGQL LAKACWNPFI LAYDESQKIL IWCLCCLINK EPQNSGQSKL NSWIQGVLSH ILSALRFDKE VALFTQGLGY APIDYYPGLL KNMVLSLASE LRENHLNGFN TQRRMAPERV ASLSRVCVPL ITLTDVDPLV EALLICHGRE PQEILQPEFF EAVNEAILLK KISLPMSAVV CLWLRHLPSL EKAMLHLFEK LISSERNCLR RIECFIKDSS LPQAACHPAI FRVVDEMFRC ALLETDGALE IIATIQVFTQ CFVEALEKAS KQLRFALKTY FPYTSPSLAM VLLQDPQDIP RGHWLQTLKH ISELLREAVE DQTHGSCGGP FESWFLFIHF GGWAEMVAEQ LLMSAAEPPT ALLWLLAFYY GPRDGRQQRA QTMVQVKAVL GHLLAMSRSS SLSAQDLQTV AGQGTDTDLR APAQQLIRHL LLNFLLWAPG GHTIAWDVIT LMAHTAEITH EIIGFLDQTL YRWNRLGIES PRSEKLAREL LKELRTQV
Genular Protein ID: 1906147297
Symbol: A0A087WW44_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 492
- Mass: 56086
- Checksum: 63A50D0F9EF75636
- Sequence:
MAQDSVDLSC DYQFWMQKLS VWDQASTLET QQDTCLHVAQ FQEFLRKMYE ALKEMDSNTV IERFPTIGQL LAKACWNPFI LAYDESQKIL IWCLCCLINK EPQNSGQSKL NSWIQGVLSH ILSALRFDKE VALFTQGLGY APIDYYPGLL KNMVLSLASE LRENHLNGFN TQRRMAPERV ASLSRVCVPL ITLTDVDPLV EALLICHGRE PQEILQPEFF EAVNEAILLK KISLPMSAVV CLWLRHLPSL EKAMLHLFEK LISSERNCLR RIECFIKDSS LPQAACHPAI FRVVDEMFRC ALLETDGALE IIATIQVFTQ CFVEALEKAS KQLRFALKTY FPYTSPSLAM VLLQDPQDIP RGHWLQTLKH ISELLREAVE DQTHGSCGGP FESWFLFIHF GGWAEMVAEQ LLMSAAEPPT ALLWLLAFYY GPRDGRQQRA QTMMAYVMAT CRHGDLQPCG QRRSPVPTEV ARDETLPAHS PAKRRPFFPK VI
Genular Protein ID: 590067639
Symbol: B4E3W2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 115
- Mass: 13462
- Checksum: 5D832FCF479412FD
- Sequence:
MAQDSVDLSC DYQFWMQKLS VWDQASTLET QQDTCLHVAQ FQEFLRKMYE ALKEMDSNTV IERFPTIGQL LAKACWNPFI LAYDESQKIL IWCLCCLINK EPQNSGQSKL NSWIQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.