Details for: FBLN1

Gene ID: 2192

Symbol: FBLN1

Ensembl ID: ENSG00000077942

Description: fibulin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 297.4698
    Cell Significance Index: -46.2700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 184.1562
    Cell Significance Index: -46.7100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 91.7030
    Cell Significance Index: -37.2600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 90.3367
    Cell Significance Index: -42.6500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 38.8115
    Cell Significance Index: -37.0600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 37.5277
    Cell Significance Index: -46.2700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.5470
    Cell Significance Index: -45.5700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 10.1753
    Cell Significance Index: 271.7000
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 9.9818
    Cell Significance Index: 61.7600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.0446
    Cell Significance Index: -27.7800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 7.5559
    Cell Significance Index: 147.4700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 7.3566
    Cell Significance Index: 67.7500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 7.1951
    Cell Significance Index: 150.6100
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 7.0477
    Cell Significance Index: 40.4100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 6.5129
    Cell Significance Index: 208.6000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 6.2977
    Cell Significance Index: 42.6700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 5.3039
    Cell Significance Index: 152.0400
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 4.5337
    Cell Significance Index: 28.1700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.8429
    Cell Significance Index: 49.2200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 3.1797
    Cell Significance Index: 573.2100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 2.5121
    Cell Significance Index: 27.3100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.4884
    Cell Significance Index: 86.4700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.1316
    Cell Significance Index: 262.1000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.9474
    Cell Significance Index: 1063.5400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.8006
    Cell Significance Index: 247.2700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.7861
    Cell Significance Index: 38.7000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.5136
    Cell Significance Index: 42.3000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2550
    Cell Significance Index: 249.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.0195
    Cell Significance Index: 52.9600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8446
    Cell Significance Index: 108.2700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.8009
    Cell Significance Index: 354.0900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.7317
    Cell Significance Index: 36.9800
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 0.7036
    Cell Significance Index: 7.6800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6794
    Cell Significance Index: 129.2900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4953
    Cell Significance Index: 22.4500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4253
    Cell Significance Index: 30.0800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.4188
    Cell Significance Index: 6.4800
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.3984
    Cell Significance Index: 0.9200
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: 0.3575
    Cell Significance Index: 1.7100
  • Cell Name: chondroblast (CL0000058)
    Fold Change: 0.3543
    Cell Significance Index: 2.0800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.3468
    Cell Significance Index: 4.9800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3267
    Cell Significance Index: 294.9800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2622
    Cell Significance Index: 25.9400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2192
    Cell Significance Index: 12.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1871
    Cell Significance Index: 118.8500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1509
    Cell Significance Index: 24.5400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0648
    Cell Significance Index: 119.5500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0460
    Cell Significance Index: 0.7700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0021
    Cell Significance Index: 0.0500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0017
    Cell Significance Index: 2.6700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0014
    Cell Significance Index: 2.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0139
    Cell Significance Index: -0.4900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0255
    Cell Significance Index: -2.7800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0367
    Cell Significance Index: -49.9200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0432
    Cell Significance Index: -32.6700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0489
    Cell Significance Index: -1.4100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0574
    Cell Significance Index: -42.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0740
    Cell Significance Index: -54.8400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0827
    Cell Significance Index: -51.6200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0879
    Cell Significance Index: -39.9100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0906
    Cell Significance Index: -51.1000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0932
    Cell Significance Index: -2.3300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.1128
    Cell Significance Index: -40.4700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1350
    Cell Significance Index: -15.7400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1416
    Cell Significance Index: -40.7400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1784
    Cell Significance Index: -10.9400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.1908
    Cell Significance Index: -38.2800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1974
    Cell Significance Index: -28.7000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2056
    Cell Significance Index: -12.6400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2186
    Cell Significance Index: -5.9500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2637
    Cell Significance Index: -55.5400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2953
    Cell Significance Index: -38.1500
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.3180
    Cell Significance Index: -2.0000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.3285
    Cell Significance Index: -22.7200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3310
    Cell Significance Index: -56.5200
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.3643
    Cell Significance Index: -3.4600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.3731
    Cell Significance Index: -22.4000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.4042
    Cell Significance Index: -41.2900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4255
    Cell Significance Index: -31.7100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4362
    Cell Significance Index: -45.4200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4508
    Cell Significance Index: -21.1900
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.4523
    Cell Significance Index: -4.3600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4697
    Cell Significance Index: -53.8100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4718
    Cell Significance Index: -36.2100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.5635
    Cell Significance Index: -8.9400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5672
    Cell Significance Index: -29.5500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6620
    Cell Significance Index: -44.5100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6696
    Cell Significance Index: -43.2000
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.8332
    Cell Significance Index: -13.7300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.8414
    Cell Significance Index: -17.9200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8609
    Cell Significance Index: -22.1300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.8927
    Cell Significance Index: -20.6300
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.9477
    Cell Significance Index: -7.5400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.0021
    Cell Significance Index: -26.3500
  • Cell Name: muscle fibroblast (CL1001609)
    Fold Change: -1.0105
    Cell Significance Index: -6.1900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.0251
    Cell Significance Index: -21.2700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -1.1052
    Cell Significance Index: -48.0600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.1100
    Cell Significance Index: -49.1000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.1129
    Cell Significance Index: -58.4300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.1567
    Cell Significance Index: -34.0700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** Fibulin-1 is a type of ECM protein that belongs to the fibulin family, which is characterized by its ability to form elastic fibers and interact with various ECM components. FBLN1 is predominantly expressed in skin fibroblasts, connective tissue fibroblasts, and other cell types involved in tissue repair and maintenance. Its expression is also observed in embryonic development, where it plays a crucial role in embryo implantation and tissue morphogenesis. **Pathways and Functions:** Fibulin-1 interacts with various ECM components, including collagen, elastin, and fibrinogen, to regulate cell adhesion, motility, and signaling pathways. Some of the key pathways and functions of FBLN1 include: 1. **Negative regulation of cell adhesion:** FBLN1 inhibits cell adhesion by interacting with integrins and other ECM components, thereby modulating cell migration and tissue repair. 2. **Negative regulation of cell motility:** FBLN1 restricts cell motility by interacting with cytoskeletal components and modulating the activity of motor proteins. 3. **Negative regulation of the ERK1/2 cascade:** FBLN1 inhibits the activation of the ERK1/2 signaling pathway, which is involved in cell proliferation and differentiation. 4. **Negative regulation of protein phosphorylation:** FBLN1 modulates protein phosphorylation by interacting with protein kinases and phosphatases, thereby regulating cell signaling and survival pathways. **Clinical Significance:** Dysregulation of FBLN1 has been implicated in various diseases, including: 1. **Elastic fiber disorders:** Mutations in the FBLN1 gene have been associated with elastic fiber disorders, such as cutis laxa and Williams syndrome. 2. **Cancer:** FBLN1 has been shown to be overexpressed in various types of cancer, including breast, lung, and colon cancer, where it may contribute to tumor progression and metastasis. 3. **Autoimmune diseases:** FBLN1 may play a role in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and lupus, where it may contribute to tissue damage and inflammation. In conclusion, FBLN1 is a critical protein component of the extracellular matrix that regulates cell adhesion, motility, and signaling pathways. Its dysregulation has been implicated in various diseases, highlighting the importance of FBLN1 in maintaining tissue homeostasis and immune function. Further research is needed to fully elucidate the mechanisms of FBLN1 and its clinical significance.

Genular Protein ID: 984223866

Symbol: FBLN1_HUMAN

Name: Fibulin-1

UniProtKB Accession Codes:

P23142 B0QY42 B1AHL4 P23143 P23144 P37888 Q5TIC4 Q8TBH8 Q9HBQ5 Q9UC21 Q9UGR4 Q9UH41

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 2 CPTAC 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 4 ExpressionAtlas 1 GO 29 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 2 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SMART 3 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2269669

Title: Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure.

PubMed ID: 2269669

DOI: 10.1083/jcb.111.6.3155

PubMed ID: 9106159

Title: Human fibulin-1D: molecular cloning, expression and similarity with S1-5 protein, a new member of the fibulin gene family.

PubMed ID: 9106159

DOI: 10.1016/s0945-053x(97)90021-4

PubMed ID: 10318851

Title: Translational control of specific genes during differentiation of HL-60 cells.

PubMed ID: 10318851

DOI: 10.1074/jbc.274.20.14295

PubMed ID: 15498874

Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.

PubMed ID: 15498874

DOI: 10.1073/pnas.0404089101

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11829738

Title: Structural and functional characterization of the human and mouse fibulin-1 gene promoters: role of Sp1 and Sp3.

PubMed ID: 11829738

DOI: 10.1042/0264-6021:3620041

PubMed ID: 2527614

Title: Fibulin, a novel protein that interacts with the fibronectin receptor beta subunit cytoplasmic domain.

PubMed ID: 2527614

DOI: 10.1016/0092-8674(89)90097-4

PubMed ID: 1400330

Title: Fibulin binds to itself and to the carboxyl-terminal heparin-binding region of fibronectin.

PubMed ID: 1400330

DOI: 10.1016/s0021-9258(19)88674-x

PubMed ID: 7534784

Title: The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study.

PubMed ID: 7534784

DOI: 10.1177/43.4.7534784

PubMed ID: 7642629

Title: The interaction of fibulin-1 with fibrinogen. A potential role in hemostasis and thrombosis.

PubMed ID: 7642629

DOI: 10.1074/jbc.270.33.19458

PubMed ID: 8737292

Title: The extracellular matrix proteins fibulin-1 and fibulin-2 in the early human embryo.

PubMed ID: 8737292

DOI: 10.1007/bf02331415

PubMed ID: 8552629

Title: Estrogens increase the expression of fibulin-1, an extracellular matrix protein secreted by human ovarian cancer cells.

PubMed ID: 8552629

DOI: 10.1073/pnas.93.1.316

PubMed ID: 9278415

Title: The self-association and fibronectin-binding sites of fibulin-1 map to calcium-binding epidermal growth factor-like domains.

PubMed ID: 9278415

DOI: 10.1074/jbc.272.36.22600

PubMed ID: 9393974

Title: Suppression of anchorage-independent growth and matrigel invasion and delayed tumor formation by elevated expression of fibulin-1D in human fibrosarcoma-derived cell lines.

PubMed ID: 9393974

DOI: 10.1038/sj.onc.1201385

PubMed ID: 9811350

Title: Increased immunostaining of fibulin-1, an estrogen-regulated protein in the stroma of human ovarian epithelial tumors.

PubMed ID: 9811350

DOI: 10.1016/s0002-9440(10)65746-x

PubMed ID: 9466671

Title: Estradiol and fibulin-1 inhibit motility of human ovarian- and breast-cancer cells induced by fibronectin.

PubMed ID: 9466671

DOI: 10.1002/(sici)1097-0215(19980209)75:4<654::aid-ijc26>3.0.co;2-7

PubMed ID: 9927660

Title: The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling.

PubMed ID: 9927660

DOI: 10.1073/pnas.96.3.869

PubMed ID: 11792823

Title: Fibulin-1 suppression of fibronectin-regulated cell adhesion and motility.

PubMed ID: 11792823

DOI: 10.1242/jcs.114.24.4587

PubMed ID: 11238726

Title: Fibulin-1 binds the amino-terminal head of beta-amyloid precursor protein and modulates its physiological function.

PubMed ID: 11238726

DOI: 10.1046/j.1471-4159.2001.00144.x

PubMed ID: 12200142

Title: Interaction of oncogenic papillomavirus E6 proteins with fibulin-1.

PubMed ID: 12200142

DOI: 10.1016/s0006-291x(02)02041-7

PubMed ID: 11836357

Title: The fibulin-1 gene (FBLN1) is disrupted in a t(12;22) associated with a complex type of synpolydactyly.

PubMed ID: 11836357

DOI: 10.1136/jmg.39.2.98

PubMed ID: 11850827

Title: Estrogen induction and overexpression of fibulin-1C mRNA in ovarian cancer cells.

PubMed ID: 11850827

DOI: 10.1038/sj.onc.1205171

PubMed ID: 12644824

Title: Elevated expression and altered processing of fibulin-1 protein in human breast cancer.

PubMed ID: 12644824

DOI: 10.1038/sj.bjc.6600802

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24084572

Title: Mutation of fibulin-1 causes a novel syndrome involving the central nervous system and connective tissues.

PubMed ID: 24084572

DOI: 10.1038/ejhg.2013.210

Sequence Information:

  • Length: 703
  • Mass: 77214
  • Checksum: 302F7ED2DF34CA71
  • Sequence:
    • MERAAPSRRV PLPLLLLGGL ALLAAGVDAD VLLEACCADG HRMATHQKDC SLPYATESKE 
CRMVQEQCCH SQLEELHCAT GISLANEQDR CATPHGDNAS LEATFVKRCC HCCLLGRAAQ 
AQGQSCEYSL MVGYQCGQVF QACCVKSQET GDLDVGGLQE TDKIIEVEEE QEDPYLNDRC 
RGGGPCKQQC RDTGDEVVCS CFVGYQLLSD GVSCEDVNEC ITGSHSCRLG ESCINTVGSF 
RCQRDSSCGT GYELTEDNSC KDIDECESGI HNCLPDFICQ NTLGSFRCRP KLQCKSGFIQ 
DALGNCIDIN ECLSISAPCP IGHTCINTEG SYTCQKNVPN CGRGYHLNEE GTRCVDVDEC 
APPAEPCGKG HRCVNSPGSF RCECKTGYYF DGISRMCVDV NECQRYPGRL CGHKCENTLG 
SYLCSCSVGF RLSVDGRSCE DINECSSSPC SQECANVYGS YQCYCRRGYQ LSDVDGVTCE 
DIDECALPTG GHICSYRCIN IPGSFQCSCP SSGYRLAPNG RNCQDIDECV TGIHNCSINE 
TCFNIQGGFR CLAFECPENY RRSAATLQQE KTDTVRCIKS CRPNDVTCVF DPVHTISHTV 
ISLPTFREFT RPEEIIFLRA ITPPHPASQA NIIFDITEGN LRDSFDIIKR YMDGMTVGVV 
RQVRPIVGPF HAVLKLEMNY VVGGVVSHRN VVNVHIFVSE YWF

Genular Protein ID: 853832457

Symbol: A0A8S0LWY1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8S0LWY1

Database IDs:

ARBA 9 CDD 2 CTD 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 10 NCBI Taxonomy 1 OMA 1 PANTHER 2 PIRNR 1 PIRSF 1 PROSITE 8 PROSITE-ProRule 1 Pfam 4 RefSeq 1 SAM 1 SMART 3 SUPFAM 2

Sequence Information:

  • Length: 683
  • Mass: 74434
  • Checksum: B6B9ED49F590F612
  • Sequence:
    • MERAAPSRRV PLPLLLLGGL ALLAAGVDAD VLLEACCADG HRMATHQKDC SLPYATESKE 
CRMVQEQCCH SQLEELHCAT GISLANEQDR CATPHGDNAS LEATFVKRCC HCCLLGRAAQ 
AQGQSCEYSL MVGYQCGQVF QACCVKSQET GDLDVGGLQE TDKIIEVEEE QEDPYLNDRC 
RGGGPCKQQC RDTGDEVVCS CFVGYQLLSD GVSCEDVNEC ITGSHSCRLG ESCINTVGSF 
RCQRDSSCGT GYELTEDNSC KDIDECESGI HNCLPDFICQ NTLGSFRCRP KLQCKSGFIQ 
DALGNCIDIN ECLSISAPCP IGHTCINTEG SYTCQKNVPN CGRGYHLNEE GTRCVDVDEC 
APPAEPCGKG HRCVNSPGSF RCECKTGYYF DGISRMCVDV NECQRYPGRL CGHKCENTLG 
SYLCSCSVGF RLSVDGRSCE DINECSSSPC SQECANVYGS YQCYCRRGYQ LSDVDGVTCE 
DIDECALPTG GHICSYRCIN IPGSFQCSCP SSGYRLAPNG RNCQDIDECV TGIHNCSINE 
TCFNIQGGFR CLAFECPENY RRSAATRCER LPCHENRECS KLPLRITYYH LSFPTNIQAP 
AVVFRMGPSS AVPGDSMQLA ITGGNEEGFF TTRKVSPHSG VVALTKPVPE PRDLLLTVKM 
DLSRHGTVSS FVAKLFIFVS AEL

Genular Protein ID: 1016350031

Symbol: Q8NBH6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NBH6

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PROSITE 5 PROSITE-ProRule 1 Pfam 3 RefSeq 2 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 638
  • Mass: 70578
  • Checksum: EBC0DE3147A7621F
  • Sequence:
    • MSSWRPAVRT DTGWPLIRRT ARCHMLRNPK NAGWCRSSAA TASWRSCTVP RASAWPTSRT 
AVPRPMVGYQ CGQVFRACCV KSQETGDLDV GGLQETDKII EVEEEQEDPY LNDRCRGGGP 
CKQQCRDTGD EVVCSCFVGY QLLSDGVSCE DVNECITGSH SCRLGESCIN TVGSFRCQRD 
SSCGTGYELT EDNSCKDIDE CESGIHNCLP DFICQNTLGS FRCRPKLQCK SGFIQDALGN 
CIDINECLSI SAPCPIGHTC INTEGSYTCQ KNVPNCGRGY HLNEEGTRCV DVDECAPPAE 
PCGKGHRCVN SPGSFRCECK TGYYFDGISR MCVDVNECQR YPGRLCGHKC ENTLGSYLCS 
CSVGFRLSVD GRSCEDINEC SSSPCSQECA NVYGSYQCYC RRGYQLSDVD GVTCEDIDEC 
ALPTGGHICS YRCINIPGSF QCSCPSSGYR LAPNGRNCQD IDECVTGIHN CSINETCFNI 
QGGFRCLAFE CPENYRRSAA TLQQEKTDTV RCIKSCRPND VTCVFDPVHT ISHTVISLPT 
FREFTRPEEI IFLRAITPPH PASQANIIFD ITEGNLRDSF DIIKRYMDGM TVGVVRQVRP 
IVGPFHAVLK LEMNYVVGGV VSHRNVVNVH IFVSEYWF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.