Details for: FDFT1

Gene ID: 2222

Symbol: FDFT1

Ensembl ID: ENSG00000079459

Description: farnesyl-diphosphate farnesyltransferase 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 4.25
    Marker Score: 75493
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.76
    Marker Score: 9058
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 2.51
    Marker Score: 5294
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.33
    Marker Score: 14913
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.31
    Marker Score: 4684.5
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 2.17
    Marker Score: 3490
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 2.15
    Marker Score: 2321
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 2.12
    Marker Score: 6657
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 2.09
    Marker Score: 3815
  • Cell Name: club cell (CL0000158)
    Fold Change: 2.05
    Marker Score: 2394
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.05
    Marker Score: 8044
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 2.04
    Marker Score: 13284
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 2.02
    Marker Score: 8279
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.99
    Marker Score: 2927
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.98
    Marker Score: 2846
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.96
    Marker Score: 67808.5
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.94
    Marker Score: 22495.5
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.87
    Marker Score: 4272
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 1.87
    Marker Score: 1672
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.87
    Marker Score: 7825
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.84
    Marker Score: 1851
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.81
    Marker Score: 2181.5
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.8
    Marker Score: 2870
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.8
    Marker Score: 10671
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.79
    Marker Score: 2537
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.79
    Marker Score: 15385
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.78
    Marker Score: 935
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.77
    Marker Score: 3131
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 1.76
    Marker Score: 648
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.75
    Marker Score: 1267
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 1.75
    Marker Score: 1650
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.71
    Marker Score: 1427
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.7
    Marker Score: 490
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.69
    Marker Score: 16981.5
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.67
    Marker Score: 3935
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.66
    Marker Score: 8700
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.65
    Marker Score: 772
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.65
    Marker Score: 521.5
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.65
    Marker Score: 3447
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.64
    Marker Score: 14253
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.63
    Marker Score: 1287
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.63
    Marker Score: 660
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.62
    Marker Score: 467
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.62
    Marker Score: 3875
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.61
    Marker Score: 10282
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.61
    Marker Score: 2014
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.6
    Marker Score: 34066
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.59
    Marker Score: 1064
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.59
    Marker Score: 509
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.56
    Marker Score: 1139
  • Cell Name: oocyte (CL0000023)
    Fold Change: 1.56
    Marker Score: 385
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.55
    Marker Score: 5992
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.55
    Marker Score: 6003
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 1.54
    Marker Score: 1818
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.53
    Marker Score: 2675
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.53
    Marker Score: 2607.5
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 1.52
    Marker Score: 1429
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.51
    Marker Score: 529
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.51
    Marker Score: 3423
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.51
    Marker Score: 1595
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.51
    Marker Score: 15264
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.5
    Marker Score: 1598
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.5
    Marker Score: 1018.5
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.49
    Marker Score: 708
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.49
    Marker Score: 23945
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 1.49
    Marker Score: 1440
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.49
    Marker Score: 867
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.48
    Marker Score: 10985
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.47
    Marker Score: 4012
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.47
    Marker Score: 37746
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 1.47
    Marker Score: 720
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 1.47
    Marker Score: 1529
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 1.46
    Marker Score: 898
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 1.46
    Marker Score: 1400
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 1.45
    Marker Score: 849
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.45
    Marker Score: 6950
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.44
    Marker Score: 1593
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 1.44
    Marker Score: 2574
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.44
    Marker Score: 165259
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 1.44
    Marker Score: 1730
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.43
    Marker Score: 11200
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 1.43
    Marker Score: 1378
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.43
    Marker Score: 3555
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 1.42
    Marker Score: 478
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.42
    Marker Score: 4887
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.42
    Marker Score: 1002
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.42
    Marker Score: 780
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 1.42
    Marker Score: 1069
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 1.41
    Marker Score: 697
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.41
    Marker Score: 3350
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.41
    Marker Score: 1875
  • Cell Name: peptic cell (CL0000155)
    Fold Change: 1.41
    Marker Score: 589
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.4
    Marker Score: 74228
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.4
    Marker Score: 2744
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.4
    Marker Score: 1803
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.39
    Marker Score: 4395.5
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 1.39
    Marker Score: 493
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 1.38
    Marker Score: 438
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 1.38
    Marker Score: 18499.5
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.37
    Marker Score: 938

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key characteristics:** * The protein is a transmembrane protein that is expressed in the endoplasmic reticulum. * It is a key enzyme in the cholesterol biosynthetic pathway. * It is a regulator of cholesterol biosynthesis by binding to the Srebp complex and facilitating its interaction with the farnesyltransferase complex. * It also regulates the activity of other enzymes in the cholesterol biosynthetic pathway. **Pathways and functions:** * Activation of gene expression by Srebp (SREBP) * Regulation of cholesterol biosynthesis by pparalpha * Regulation of lipid metabolism by ppara * Farnesyl diphosphate farnesyltransferase activity **Clinical significance:** * Mutations in the FDFT1 gene have been linked to several human diseases, including familial hypercholesterolemia and atherosclerosis. * Overexpression of FDFT1 has been linked to the development of liver cancer. * Inhibition of FDFT1 has been shown to reduce cholesterol levels and improve atherosclerotic disease in animal models. **Additional information:** * The protein is a transmembrane protein that is composed of 14 transmembrane domains. * It is a chaperone protein that is involved in the folding and stability of other proteins in the endoplasmic reticulum. * It is a highly conserved protein that is found in organisms from yeast to humans.

Genular Protein ID: 4054647806

Symbol: FDFT_HUMAN

Name: Squalene synthase

UniProtKB Accession Codes:

P37268 B3KQ95 B4DJE5 B4DT56 B7Z1J3 Q96GT0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 36 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 2 EMBL 16 EPD 1 Ensembl 16 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 35 PDBsum 30 PIR 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 3 RefSeq 12 Rhea 10 SABIO-RK 1 SFLD 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8474436

Title: Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation.

PubMed ID: 8474436

DOI: 10.1128/mcb.13.5.2706-2717.1993

PubMed ID: 7685352

Title: Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase.

PubMed ID: 7685352

DOI: 10.1016/s0021-9258(18)31461-3

PubMed ID: 8294001

Title: Cloning, expression and characterisation of the cDNA encoding human hepatic squalene synthase, and its relationship to phytoene synthase.

PubMed ID: 8294001

DOI: 10.1016/0378-1119(93)90462-c

PubMed ID: 7864626

Title: Expression, purification, and characterization of the human squalene synthase: use of yeast and baculoviral systems.

PubMed ID: 7864626

DOI: 10.1006/abbi.1995.1095

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29909962

Title: Squalene synthase deficiency: clinical, biochemical, and molecular characterization of a defect in cholesterol biosynthesis.

PubMed ID: 29909962

DOI: 10.1016/j.ajhg.2018.05.004

PubMed ID: 10896663

Title: Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis.

PubMed ID: 10896663

DOI: 10.1074/jbc.m004132200

PubMed ID: 24531458

Title: Structural insights into the catalytic mechanism of human squalene synthase.

PubMed ID: 24531458

DOI: 10.1107/s1399004713026230

PubMed ID: 18350552

Title: K45R variant of squalene synthase increases total cholesterol levels in two study samples from a French Canadian population.

PubMed ID: 18350552

DOI: 10.1002/humu.20702

Sequence Information:

  • Length: 417
  • Mass: 48115
  • Checksum: D36CBC8382F827EC
  • Sequence:
    • MEFVKCLGHP EEFYNLVRFR IGGKRKVMPK MDQDSLSSSL KTCYKYLNQT SRSFAAVIQA 
LDGEMRNAVC IFYLVLRALD TLEDDMTISV EKKVPLLHNF HSFLYQPDWR FMESKEKDRQ 
VLEDFPTISL EFRNLAEKYQ TVIADICRRM GIGMAEFLDK HVTSEQEWDK YCHYVAGLVG 
IGLSRLFSAS EFEDPLVGED TERANSMGLF LQKTNIIRDY LEDQQGGREF WPQEVWSRYV 
KKLGDFAKPE NIDLAVQCLN ELITNALHHI PDVITYLSRL RNQSVFNFCA IPQVMAIATL 
AACYNNQQVF KGAVKIRKGQ AVTLMMDATN MPAVKAIIYQ YMEEIYHRIP DSDPSSSKTR 
QIISTIRTQN LPNCQLISRS HYSPIYLSFV MLLAALSWQY LTTLSQVTED YVQTGEH

Genular Protein ID: 86579480

Symbol: B4DND3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DND3

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 28 DNASU 1 EC 2 EMBL 4 GO 4 Gene3D 1 GenomeRNAi 1 InterPro 6 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 8 RuleBase 1 SFLD 2 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 474
  • Mass: 53405
  • Checksum: 82E726FC8132DEC2
  • Sequence:
    • MAAAACGTKA MALFKRTLVL SPAAAPRGPG AGTAPRGCCL PPAAWPCKDW PRGEGGRLWS 
RLPQSHSHSH SHSHSCSSTS PTAVCVVCPQ DSLSSSLKTC YKYLNQTSRS FAAVIQALDG 
EMRNAVCIFY LVLRALDTLE DDMTISVEKK VPLLHNFHSF LYQPDWRFME SKEKDRQVLE 
DFPTISLEFR NLAEKYQTVI ADICRRMGIG MAEFLDKHVT SEQEWDKYCH YVAGLVGIGL 
SRLFSASEFE DPLVGEDTER ANSMGLFLQK TNIIRDYLED QQGGREFWPQ EVWSRYVKKL 
GDFAKPENID LAVQCLNELI TNALHHIPDV ITYLSRLRNQ SVFNFCAIPQ VMAIATLAAC 
YNNQQVFKGA VKIRKGQAVT LMMDATNMPA VKAIIYQYME EIYHRIPDSD PSSSKTRQII 
STIRTQNLPN CQLISRSHYS PIYLSFVMLL AALSWQYLTT LSQVTEDYVQ TGEH

Genular Protein ID: 2015382974

Symbol: A0A1W2PQ47_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A1W2PQ47

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChEBI 28 ChiTaRS 1 DNASU 1 EC 2 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 Rhea 8 RuleBase 1 SAM 1 SFLD 2 SMR 1 SUPFAM 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 476
  • Mass: 53629
  • Checksum: B9EC08472E44D84D
  • Sequence:
    • MAAAACGTKA MALFKRTLVL SPAAAPRGPG AGTAPRGCCL PPAAWPCKDW PRGEGGRLWS 
RLPQSHSHSH SHSHSHSCSS TSPTAVCVVC PQDSLSSSLK TCYKYLNQTS RSFAAVIQAL 
DGEMRNAVCI FYLVLRALDT LEDDMTISVE KKVPLLHNFH SFLYQPDWRF MESKEKDRQV 
LEDFPTISLE FRNLAEKYQT VIADICRRMG IGMAEFLDKH VTSEQEWDKY CHYVAGLVGI 
GLSRLFSASE FEDPLVGEDT ERANSMGLFL QKTNIIRDYL EDQQGGREFW PQEVWSRYVK 
KLGDFAKPEN IDLAVQCLNE LITNALHHIP DVITYLSRLR NQSVFNFCAI PQVMAIATLA 
ACYNNQQVFK GAVKIRKGQA VTLMMDATNM PAVKAIIYQY MEEIYHRIPD SDPSSSKTRQ 
IISTIRTQNL PNCQLISRSH YSPIYLSFVM LLAALSWQYL TTLSQVTEDY VQTGEH

Genular Protein ID: 3298542456

Symbol: B4DWP0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DWP0

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 16 DNASU 1 EMBL 2 GO 3 Gene3D 1 GenomeRNAi 1 InterPro 5 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 1 Pfam 1 RefSeq 1 Rhea 6 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 250
  • Mass: 28529
  • Checksum: E37F827A1D5D439D
  • Sequence:
    • MPWPPRRVLQ PGALPDRGQA EASEFEDPLV GEDTERANSM GLFLQKTNII RDYLEDQQGG 
REFWPQEVWS RYVKKLGDFA KPENIDLAVQ CLNELITNAL HHIPDVITYL SRLRNQSVFN 
FCAIPQVMAI ATLAACYNNQ QVFKGAVKIR KGQAVTLMMD ATNMPAVKAI IYQYMEEIYH 
RIPDSDPSSS KTRQIISTIR TQNLPNCQLI SRSHYSPIYL SFVMLLAALS WQYLTTLSQV 
TEDYVQTGEH

Genular Protein ID: 1050176898

Symbol: B7Z9R8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z9R8

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 28 DNASU 1 EC 2 EMBL 2 GO 4 Gene3D 1 GenomeRNAi 1 InterPro 6 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 8 RuleBase 1 SFLD 2 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 353
  • Mass: 40754
  • Checksum: 45C1DF579F179D2B
  • Sequence:
    • MRNAVCIFYL VLRALDTLED DMTISVEKKV PLLHNFHSFL YQPDWRFMES KEKDRQVLED 
FPTISLEFRN LAEKYQTVIA DICRRMGIGM AEFLDKHVTS EQEWDKYCHY VAGLVGIGLS 
RLFSASEFED PLVGEDTERA NSMGLFLQKT NIIRDYLEDQ QGGREFWPQE VWSRYVKKLG 
DFAKPENIDL AVQCLNELIT NALHHIPDVI TYLSRLRNQS VFNFCAIPQV MAIATLAACY 
NNQQVFKGAV KIRKGQAVTL MMDATNMPAV KAIIYQYMEE IYHRIPDSDP SSSKTRQIIS 
TIRTQNLPNC QLISRSHYSP IYLSFVMPLA ALSWQYLTTL SQVTEDYVQT GEH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.