Details for: GBP2

Gene ID: 2634

Symbol: GBP2

Ensembl ID: ENSG00000162645

Description: guanylate binding protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 190.6198
    Cell Significance Index: -29.6500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 91.8613
    Cell Significance Index: -23.3000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 75.6650
    Cell Significance Index: -31.1700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 60.7893
    Cell Significance Index: -28.7000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 58.3998
    Cell Significance Index: -30.0400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 43.6498
    Cell Significance Index: -29.2900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 24.0803
    Cell Significance Index: -29.6900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.7520
    Cell Significance Index: -23.8100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.5645
    Cell Significance Index: -29.8500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.3273
    Cell Significance Index: -16.9500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 3.3791
    Cell Significance Index: 99.2400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.7631
    Cell Significance Index: 75.2100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.5223
    Cell Significance Index: 323.3500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.2169
    Cell Significance Index: 115.1600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.9196
    Cell Significance Index: 248.0000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.7292
    Cell Significance Index: 31.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.4812
    Cell Significance Index: 69.6200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.3378
    Cell Significance Index: 23.6400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.1285
    Cell Significance Index: 12.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.0342
    Cell Significance Index: 77.0800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9982
    Cell Significance Index: 901.3200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8845
    Cell Significance Index: 121.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7627
    Cell Significance Index: 137.5000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.7528
    Cell Significance Index: 21.5800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5956
    Cell Significance Index: 58.9200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5594
    Cell Significance Index: 247.3300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.5511
    Cell Significance Index: 27.8500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4775
    Cell Significance Index: 33.0200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.4693
    Cell Significance Index: 12.5800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4530
    Cell Significance Index: 55.7100
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.4108
    Cell Significance Index: 2.9500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.4073
    Cell Significance Index: 7.9500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3139
    Cell Significance Index: 171.4400
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.2299
    Cell Significance Index: 1.4200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2003
    Cell Significance Index: 4.3400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1220
    Cell Significance Index: 3.4100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1207
    Cell Significance Index: 19.6300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.1077
    Cell Significance Index: 1.1200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1054
    Cell Significance Index: 2.6400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1043
    Cell Significance Index: 7.3800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1036
    Cell Significance Index: 19.7200
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.0679
    Cell Significance Index: 0.3700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0363
    Cell Significance Index: 16.4800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0324
    Cell Significance Index: 1.4700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0243
    Cell Significance Index: 15.1600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0205
    Cell Significance Index: 0.7200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0120
    Cell Significance Index: 0.3200
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.0048
    Cell Significance Index: -0.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0065
    Cell Significance Index: -12.3100
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: -0.0076
    Cell Significance Index: -0.0400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0125
    Cell Significance Index: -0.1100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0140
    Cell Significance Index: -2.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0144
    Cell Significance Index: -10.6900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0181
    Cell Significance Index: -33.4200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0211
    Cell Significance Index: -32.4800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0250
    Cell Significance Index: -33.9900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0264
    Cell Significance Index: -5.2500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0282
    Cell Significance Index: -15.9300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0282
    Cell Significance Index: -21.3300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0324
    Cell Significance Index: -20.5600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0346
    Cell Significance Index: -3.5300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0393
    Cell Significance Index: -28.8100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0783
    Cell Significance Index: -28.0700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0855
    Cell Significance Index: -24.6100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0885
    Cell Significance Index: -10.3100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0909
    Cell Significance Index: -19.1400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0980
    Cell Significance Index: -19.6500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1140
    Cell Significance Index: -13.0700
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.1299
    Cell Significance Index: -2.2400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1473
    Cell Significance Index: -21.4100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1557
    Cell Significance Index: -17.7700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1682
    Cell Significance Index: -3.8900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1744
    Cell Significance Index: -8.1300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1804
    Cell Significance Index: -21.2800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1944
    Cell Significance Index: -11.9200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1984
    Cell Significance Index: -20.6600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2078
    Cell Significance Index: -3.5000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2409
    Cell Significance Index: -15.5400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.2845
    Cell Significance Index: -2.3900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3717
    Cell Significance Index: -29.4400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3754
    Cell Significance Index: -28.8100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.4005
    Cell Significance Index: -5.7600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4254
    Cell Significance Index: -11.3800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4343
    Cell Significance Index: -29.2100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4627
    Cell Significance Index: -28.4400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4630
    Cell Significance Index: -9.8600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4877
    Cell Significance Index: -30.7400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5512
    Cell Significance Index: -30.9300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5768
    Cell Significance Index: -7.8700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5836
    Cell Significance Index: -30.6400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.6142
    Cell Significance Index: -9.0700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6298
    Cell Significance Index: -18.5500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.6321
    Cell Significance Index: -9.7800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6486
    Cell Significance Index: -28.6900
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.6578
    Cell Significance Index: -16.4300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6769
    Cell Significance Index: -24.8500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.7104
    Cell Significance Index: -24.8900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.7455
    Cell Significance Index: -30.5500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7495
    Cell Significance Index: -28.3800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.7561
    Cell Significance Index: -19.3200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** GBP2 is a 47-kDa protein that belongs to the GBP family, characterized by its ability to bind guanosine 5'-triphosphate (GTP). This binding event triggers a series of conformational changes that enable GBP2 to interact with various signaling molecules, including interferons and cytokines. The protein's unique structure and function allow it to regulate multiple immune responses, including the activation of the innate immune response, cytokine signaling, and the regulation of immune cell function. **Pathways and Functions** GBP2 is involved in several key immune pathways, including: 1. **Activation of innate immune response**: GBP2 regulates the activation of pattern recognition receptors (PRRs) and the subsequent production of pro-inflammatory cytokines, which are essential for initiating an immune response against pathogens. 2. **Cytokine signaling**: GBP2 interacts with cytokine receptors, modulating the signaling pathways that regulate immune cell function and inflammation. 3. **Immune response to lipopolysaccharide (LPS)**: GBP2 regulates the production of pro-inflammatory cytokines in response to LPS, a key component of Gram-negative bacterial cell walls. 4. **Regulation of immune cell function**: GBP2 modulates the activity of immune cells, including T cells, macrophages, and dendritic cells, influencing their ability to recognize and respond to pathogens. **Clinical Significance** The dysregulation of GBP2 has been implicated in various diseases, including: 1. **Inflammatory disorders**: GBP2 has been shown to play a role in the pathogenesis of inflammatory diseases, such as rheumatoid arthritis and atherosclerosis. 2. **Cancer**: GBP2 has been implicated in the regulation of tumor immune evasion and the promotion of cancer progression. 3. **Autoimmune diseases**: GBP2 has been shown to contribute to the development of autoimmune diseases, such as multiple sclerosis and lupus. 4. **Viral infections**: GBP2 has been implicated in the regulation of immune responses to viral infections, including HIV and influenza. In summary, GBP2 is a multifunctional protein that plays a critical role in regulating immune responses and maintaining tissue homeostasis. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding its mechanisms of action and potential therapeutic targets.

Genular Protein ID: 2534682353

Symbol: GBP2_HUMAN

Name: Guanylate-binding protein 2

UniProtKB Accession Codes:

P32456 Q6GPH0 Q6IAU2 Q86TB0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 8 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 GO 29 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1715024

Title: Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

PubMed ID: 1715024

DOI: 10.1128/mcb.11.9.4717-4725.1991

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706832

Title: GTPase properties of the interferon-induced human guanylate-binding protein 2.

PubMed ID: 8706832

DOI: 10.1016/0014-5793(96)00628-x

PubMed ID: 17266443

Title: Unique features of different members of the human guanylate-binding protein family.

PubMed ID: 17266443

DOI: 10.1089/jir.2007.0086

PubMed ID: 21151871

Title: Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

PubMed ID: 21151871

DOI: 10.1371/journal.pone.0014246

PubMed ID: 29024643

Title: GBPs inhibit motility of Shigella flexneri but are targeted for degradation by the bacterial ubiquitin ligase IpaH9.8.

PubMed ID: 29024643

DOI: 10.1016/j.chom.2017.09.007

PubMed ID: 29144452

Title: Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence.

PubMed ID: 29144452

DOI: 10.1038/nature24467

PubMed ID: 31091448

Title: Guanylate-binding proteins 2 and 5 exert broad antiviral activity by inhibiting furin-mediated processing of viral envelope proteins.

PubMed ID: 31091448

DOI: 10.1016/j.celrep.2019.04.063

PubMed ID: 33876762

Title: Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.

PubMed ID: 33876762

DOI: 10.1073/pnas.2022269118

Sequence Information:

  • Length: 591
  • Mass: 67209
  • Checksum: B09B3C2F3C3E1EA2
  • Sequence:
    • MAPEINLPGP MSLIDNTKGQ LVVNPEALKI LSAITQPVVV VAIVGLYRTG KSYLMNKLAG 
KKNGFSLGST VKSHTKGIWM WCVPHPKKPE HTLVLLDTEG LGDIEKGDNE NDSWIFALAI 
LLSSTFVYNS MGTINQQAMD QLHYVTELTD RIKANSSPGN NSVDDSADFV SFFPAFVWTL 
RDFTLELEVD GEPITADDYL ELSLKLRKGT DKKSKSFNDP RLCIRKFFPK RKCFVFDWPA 
PKKYLAHLEQ LKEEELNPDF IEQVAEFCSY ILSHSNVKTL SGGIPVNGPR LESLVLTYVN 
AISSGDLPCM ENAVLALAQI ENSAAVEKAI AHYEQQMGQK VQLPTETLQE LLDLHRDSER 
EAIEVFMKNS FKDVDQMFQR KLGAQLEARR DDFCKQNSKA SSDCCMALLQ DIFGPLEEDV 
KQGTFSKPGG YRLFTQKLQE LKNKYYQVPR KGIQAKEVLK KYLESKEDVA DALLQTDQSL 
SEKEKAIEVE RIKAESAEAA KKMLEEIQKK NEEMMEQKEK SYQEHVKQLT EKMERDRAQL 
MAEQEKTLAL KLQEQERLLK EGFENESKRL QKDIWDIQMR SKSLEPICNI L

Genular Protein ID: 4076545227

Symbol: Q8TCE5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8TCE5

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 481
  • Mass: 54035
  • Checksum: 2F8B66BEA92EED87
  • Sequence:
    • MAPEINLPGP MSLIDNTKGQ LVVNPEALKI LSAITQPVVV VAIVGLYRTG KSYLMNKLAG 
KKNGFSLGST VKSHTKGIWM WCVPHPKKPE HTLVLLDTEG LGDIEKGDNE NDSWIFALAI 
LLSSTFVYNS MGTINQQAMD QLHYVTELTD RIKANSSPGN NSVDDSADFV SFFPAFVWTL 
RDFTLELEVD GEPITADDYL ELSLKLRKGT DKKSKSFNDP RLCIRKFFPK RKCFVFDWPA 
PKKYLAHLEQ LKEEELNPDF IEQVAEFCSY ILSHSNVKTL SGGIPVNGPR LESLVLTYVN 
AISSGDLPCM ENAVLALAQI ENSAAVEKAI AHYEQQMGQK VQLPTETLQE LLDLHRDSER 
EAIEVFMKNS FKDVDQMFQR KLGAQLEARR DDFCKQNSKA SSDCCMALLQ DIFGPLEEDV 
KQGTFSKPGG YRLFTQKLQE LKNKYYQVPR KGIQAKEVLK KYLESKEDVA DALLQTDQSL 
S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.