Details for: SNX5

Gene ID: 27131

Symbol: SNX5

Ensembl ID: ENSG00000089006

Description: sorting nexin 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 221.7362
    Cell Significance Index: -34.4900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 130.5770
    Cell Significance Index: -33.1200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 104.2366
    Cell Significance Index: -42.9400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 95.0137
    Cell Significance Index: -38.6000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 92.6242
    Cell Significance Index: -43.7300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 84.7614
    Cell Significance Index: -43.6000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 65.3481
    Cell Significance Index: -43.8500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 40.8958
    Cell Significance Index: -39.0500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 32.0044
    Cell Significance Index: -39.4600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.4498
    Cell Significance Index: -36.0300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.7539
    Cell Significance Index: -33.0300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.3344
    Cell Significance Index: -40.7800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.8857
    Cell Significance Index: -15.0700
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 5.4495
    Cell Significance Index: 57.9000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.9249
    Cell Significance Index: 209.3700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.8634
    Cell Significance Index: 369.7900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.8370
    Cell Significance Index: 216.6400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.5366
    Cell Significance Index: 41.0300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4613
    Cell Significance Index: 1319.4200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.4305
    Cell Significance Index: 42.0100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.3072
    Cell Significance Index: 17.8400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.2401
    Cell Significance Index: 152.4900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.2116
    Cell Significance Index: 32.4700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1811
    Cell Significance Index: 645.0500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.1553
    Cell Significance Index: 12.5600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.0108
    Cell Significance Index: 182.2100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.9481
    Cell Significance Index: 130.2000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.8219
    Cell Significance Index: 58.1300
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.7668
    Cell Significance Index: 9.8200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7660
    Cell Significance Index: 34.7200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7101
    Cell Significance Index: 45.8200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.6973
    Cell Significance Index: 18.9800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6698
    Cell Significance Index: 34.8000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.6575
    Cell Significance Index: 5.2500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6203
    Cell Significance Index: 124.4300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.6190
    Cell Significance Index: 5.7000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6144
    Cell Significance Index: 17.1700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.6098
    Cell Significance Index: 28.4300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5937
    Cell Significance Index: 17.1100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5908
    Cell Significance Index: 40.8600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5277
    Cell Significance Index: 233.3100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.5172
    Cell Significance Index: 24.3100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4608
    Cell Significance Index: 59.0700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4489
    Cell Significance Index: 9.7300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4057
    Cell Significance Index: 65.9800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.3469
    Cell Significance Index: 9.2800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.2747
    Cell Significance Index: 5.7500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2316
    Cell Significance Index: 17.2600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2309
    Cell Significance Index: 82.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2086
    Cell Significance Index: 10.8700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1693
    Cell Significance Index: 21.8800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.1649
    Cell Significance Index: 3.8100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1643
    Cell Significance Index: 4.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1303
    Cell Significance Index: 7.3100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0779
    Cell Significance Index: 146.7300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0458
    Cell Significance Index: 4.5300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0373
    Cell Significance Index: 27.3800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0263
    Cell Significance Index: 5.0100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0258
    Cell Significance Index: 19.5000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0245
    Cell Significance Index: 15.5400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0166
    Cell Significance Index: 0.5800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0108
    Cell Significance Index: 7.4500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0074
    Cell Significance Index: 11.4600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0072
    Cell Significance Index: 13.3100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0111
    Cell Significance Index: -1.1300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0218
    Cell Significance Index: -29.6400
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.0311
    Cell Significance Index: -0.2300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0405
    Cell Significance Index: -18.3900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0460
    Cell Significance Index: -1.6000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0540
    Cell Significance Index: -40.0100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0541
    Cell Significance Index: -7.8700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0613
    Cell Significance Index: -10.4600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0702
    Cell Significance Index: -39.5900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0756
    Cell Significance Index: -47.1900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0783
    Cell Significance Index: -1.3100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1011
    Cell Significance Index: -29.0800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1168
    Cell Significance Index: -7.1800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1322
    Cell Significance Index: -3.7900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1333
    Cell Significance Index: -10.2300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1588
    Cell Significance Index: -5.0900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2084
    Cell Significance Index: -24.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2223
    Cell Significance Index: -25.4700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2285
    Cell Significance Index: -48.1300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.2612
    Cell Significance Index: -15.6800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2776
    Cell Significance Index: -5.1300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2842
    Cell Significance Index: -14.9200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2843
    Cell Significance Index: -29.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3072
    Cell Significance Index: -24.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3299
    Cell Significance Index: -20.7900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3491
    Cell Significance Index: -7.4400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3764
    Cell Significance Index: -9.4100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3950
    Cell Significance Index: -10.0900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4414
    Cell Significance Index: -29.6800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4679
    Cell Significance Index: -23.6400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4820
    Cell Significance Index: -4.9900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6139
    Cell Significance Index: -37.6400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6532
    Cell Significance Index: -19.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6669
    Cell Significance Index: -29.5000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.8010
    Cell Significance Index: -30.3300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8656
    Cell Significance Index: -22.2500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SNX5 is a cytoplasmic protein that belongs to the sorting nexin family, which is known for its involvement in regulating membrane trafficking and endosomal functions. The protein is characterized by its ability to interact with various proteins and lipids, including phosphatidylinositol (PI), dynactin, and cadherins. SNX5 is highly expressed in various cell types, including immune cells, epithelial cells, and hematopoietic cells. **Pathways and Functions:** SNX5 is involved in several cellular pathways, including: 1. **Membrane Trafficking:** SNX5 regulates the transport of cargoes between the endoplasmic reticulum (ER), Golgi apparatus, and plasma membrane. 2. **Endosomal Functions:** SNX5 modulates the sorting, degradation, and recycling of endosomal cargoes. 3. **Regulation of DNA-templated Transcription:** SNX5 positively regulates the transcription of genes involved in cell cycle progression and DNA repair. 4. **Insulin Receptor Signaling Pathway:** SNX5 is involved in the regulation of insulin receptor signaling, which is critical for glucose metabolism and energy homeostasis. 5. **Retrograde Transport:** SNX5 facilitates the transport of cargoes from the Golgi apparatus back to the ER. **Clinical Significance:** SNX5 has been implicated in various diseases, including: 1. **Immune Disorders:** SNX5 is highly expressed in immune cells, and alterations in its expression have been linked to autoimmune diseases, such as rheumatoid arthritis and lupus. 2. **Cancer:** SNX5 has been found to be overexpressed in several types of cancer, including breast, lung, and colon cancer, where it may contribute to tumor progression and metastasis. 3. **Neurological Disorders:** SNX5 has been implicated in the regulation of neuroinflammation and neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. 4. **Metabolic Disorders:** SNX5 is involved in the regulation of glucose metabolism and insulin signaling, making it a potential target for the treatment of metabolic disorders, such as type 2 diabetes. In conclusion, SNX5 is a multifunctional protein that plays a critical role in regulating membrane trafficking, endosomal functions, and cellular signaling pathways. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the molecular mechanisms underlying SNX5's functions and its potential as a therapeutic target.

Genular Protein ID: 3228232873

Symbol: SNX5_HUMAN

Name: Sorting nexin-5

UniProtKB Accession Codes:

Q9Y5X3 B7ZKN3 D3DW26 Q52LC4 Q7KZN0 Q9BWP0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 3 ChiTaRS 1 ComplexPortal 2 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 EMDB 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11485546

Title: A large family of endosome-localized proteins related to sorting nexin 1.

PubMed ID: 11485546

DOI: 10.1042/0264-6021:3580007

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15561769

Title: Sorting nexin 5 is localized to a subdomain of the early endosomes and is recruited to the plasma membrane following EGF stimulation.

PubMed ID: 15561769

DOI: 10.1242/jcs.01561

PubMed ID: 16857196

Title: Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish.

PubMed ID: 16857196

DOI: 10.1016/j.febslet.2006.07.009

PubMed ID: 16968745

Title: Visualisation of macropinosome maturation by the recruitment of sorting nexins.

PubMed ID: 16968745

DOI: 10.1242/jcs.03167

PubMed ID: 17148574

Title: A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer.

PubMed ID: 17148574

DOI: 10.1242/jcs.03302

PubMed ID: 18854019

Title: A role for SNX5 in the regulation of macropinocytosis.

PubMed ID: 18854019

DOI: 10.1186/1471-2121-9-58

PubMed ID: 18596235

Title: The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport.

PubMed ID: 18596235

DOI: 10.1091/mbc.e08-03-0314

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19619496

Title: The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network.

PubMed ID: 19619496

DOI: 10.1016/j.devcel.2009.04.016

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21048941

Title: The SNX-PX-BAR family in macropinocytosis: the regulation of macropinosome formation by SNX-PX-BAR proteins.

PubMed ID: 21048941

DOI: 10.1371/journal.pone.0013763

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23085988

Title: Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules.

PubMed ID: 23085988

DOI: 10.1038/emboj.2012.283

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23602387

Title: Endosomal type Igamma PIP 5-kinase controls EGF receptor lysosomal sorting.

PubMed ID: 23602387

DOI: 10.1016/j.devcel.2013.03.010

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24610942

Title: Isoform 5 of PIPKIgamma regulates the endosomal trafficking and degradation of E-cadherin.

PubMed ID: 24610942

DOI: 10.1242/jcs.132423

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29444945

Title: Interaction of Human Cytomegalovirus Tegument Proteins ppUL35 and ppUL35A with Sorting Nexin 5 Regulates Glycoprotein B (gpUL55) Localization.

PubMed ID: 29444945

DOI: 10.1128/jvi.00013-18

PubMed ID: 15226359

Title: Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion.

PubMed ID: 15226359

DOI: 10.1084/jem.20031680

Sequence Information:

  • Length: 404
  • Mass: 46816
  • Checksum: 87A85620AF827EC6
  • Sequence:
    • MAAVPELLQQ QEEDRSKLRS VSVDLNVDPS LQIDIPDALS ERDKVKFTVH TKTTLPTFQS 
PEFSVTRQHE DFVWLHDTLI ETTDYAGLII PPAPTKPDFD GPREKMQKLG EGEGSMTKEE 
FAKMKQELEA EYLAVFKKTV SSHEVFLQRL SSHPVLSKDR NFHVFLEYDQ DLSVRRKNTK 
EMFGGFFKSV VKSADEVLFT GVKEVDDFFE QEKNFLINYY NRIKDSCVKA DKMTRSHKNV 
ADDYIHTAAC LHSLALEEPT VIKKYLLKVA ELFEKLRKVE GRVSSDEDLK LTELLRYYML 
NIEAAKDLLY RRTKALIDYE NSNKALDKAR LKSKDVKLAE AHQQECCQKF EQLSESAKEE 
LINFKRKRVA AFRKNLIEMS ELEIKHARNN VSLLQSCIDL FKNN

Genular Protein ID: 3636413531

Symbol: Q6P5V6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6P5V6

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 412
  • Mass: 47438
  • Checksum: 80F6EF89031F8D0D
  • Sequence:
    • LGECPLLPVR VAALRLAASS WSGARLRSVS VDLNVDPSLQ IDIPDALSER DKVKFTVHTK 
TTLPTFQSPE FSVTRQHEDF VWLHDTLIET TDYAGLIIPP APTKPDFDGP REKMQKLGEG 
EGSMTKEEFA KMKQELEAEY LAVFKKTVSS HEVFLQRLSS HPVLSKDRNF HVFLEYDQDL 
SVRRKNTKEM FGGFFKSVVK SADEVLFTGV KEVDDFFEQE KNFLINYYNR IKDSCVKADK 
MTRSHKNVAD DYIHTAACLH SLALEEPTVI KKYLLKVAEL FEKLRKVEGR VSSDEDLKLT 
ELLRYYMLNI EAAKDLLYRR TKALIDYENS NKALDKARLK SKDVKLAEAH QQECCQKFEQ 
LSESAKEELI NFKRKRVAAF RKNLIEMSEL EIKHARNNVS LLQSCIDLFK NN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.