Details for: RBMX
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 517.5987
Cell Significance Index: -80.5100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 288.2393
Cell Significance Index: -73.1100 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 234.6415
Cell Significance Index: -96.6600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 206.4506
Cell Significance Index: -97.4700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 188.1275
Cell Significance Index: -96.7700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 145.9937
Cell Significance Index: -97.9700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 78.1942
Cell Significance Index: -96.4100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 27.5098
Cell Significance Index: -73.7000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 25.5699
Cell Significance Index: -100.9000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 24.2686
Cell Significance Index: -74.5400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 19.7662
Cell Significance Index: -43.2600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 5.3701
Cell Significance Index: 186.6100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 4.2929
Cell Significance Index: 46.6700 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 3.9256
Cell Significance Index: 82.1700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 3.8781
Cell Significance Index: 101.9800 - Cell Name: kidney cell (CL1000497)
Fold Change: 3.5232
Cell Significance Index: 28.1300 - Cell Name: theca cell (CL0000503)
Fold Change: 3.0774
Cell Significance Index: 18.0800 - Cell Name: odontoblast (CL0000060)
Fold Change: 3.0387
Cell Significance Index: 389.5400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.6438
Cell Significance Index: 325.0900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.6141
Cell Significance Index: 358.9900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.5413
Cell Significance Index: 119.4400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.5026
Cell Significance Index: 34.1500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.4604
Cell Significance Index: 443.5400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.3145
Cell Significance Index: 129.8800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.2521
Cell Significance Index: 446.9300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.2197
Cell Significance Index: 143.2100 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.0657
Cell Significance Index: 266.8800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.8924
Cell Significance Index: 24.2400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.8586
Cell Significance Index: 50.5900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.7743
Cell Significance Index: 209.2400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.5937
Cell Significance Index: 122.3000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.5554
Cell Significance Index: 687.6600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.3498
Cell Significance Index: 737.1400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.2159
Cell Significance Index: 33.9800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.2062
Cell Significance Index: 241.9600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.1931
Cell Significance Index: 427.9300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.1072
Cell Significance Index: 82.5200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.0984
Cell Significance Index: 77.6800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.0282
Cell Significance Index: 29.6300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.8943
Cell Significance Index: 54.9700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.6756
Cell Significance Index: 115.3600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.6340
Cell Significance Index: 33.2900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6010
Cell Significance Index: 59.4500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.5677
Cell Significance Index: 26.4700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5191
Cell Significance Index: 23.5300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.4623
Cell Significance Index: 8.1700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.4536
Cell Significance Index: 11.6600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.4211
Cell Significance Index: 12.0700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.3364
Cell Significance Index: 4.0100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3108
Cell Significance Index: 585.1500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2886
Cell Significance Index: 18.1900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2758
Cell Significance Index: 249.0700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2392
Cell Significance Index: 12.4300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2309
Cell Significance Index: 43.9400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1716
Cell Significance Index: 264.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1706
Cell Significance Index: 108.3800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1572
Cell Significance Index: 289.8500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1024
Cell Significance Index: 46.4600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0629
Cell Significance Index: 85.5300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0111
Cell Significance Index: 0.3900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0108
Cell Significance Index: 8.1500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0096
Cell Significance Index: 7.0400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0329
Cell Significance Index: -20.5200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0385
Cell Significance Index: -28.4900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0605
Cell Significance Index: -1.3100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0843
Cell Significance Index: -2.2500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0989
Cell Significance Index: -55.8000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1041
Cell Significance Index: -10.6300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.1471
Cell Significance Index: -23.9300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1544
Cell Significance Index: -2.2800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2322
Cell Significance Index: -48.9100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2822
Cell Significance Index: -41.0200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3158
Cell Significance Index: -90.8600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.3812
Cell Significance Index: -7.4400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.4966
Cell Significance Index: -33.3900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5051
Cell Significance Index: -58.8700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.5601
Cell Significance Index: -64.1700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.6165
Cell Significance Index: -15.7500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6985
Cell Significance Index: -11.6900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.7309
Cell Significance Index: -23.4100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.7542
Cell Significance Index: -78.5300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.7696
Cell Significance Index: -34.0400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.7813
Cell Significance Index: -19.5300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.8434
Cell Significance Index: -96.2700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.9366
Cell Significance Index: -10.6400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.9380
Cell Significance Index: -74.2900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.9816
Cell Significance Index: -37.1700 - Cell Name: peg cell (CL4033014)
Fold Change: -0.9999
Cell Significance Index: -23.1000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -1.0630
Cell Significance Index: -31.2200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -1.0970
Cell Significance Index: -18.8000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -1.1988
Cell Significance Index: -28.7500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.3066
Cell Significance Index: -90.3600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.4358
Cell Significance Index: -88.0300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -1.4899
Cell Significance Index: -13.7200 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -1.6127
Cell Significance Index: -39.3500 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -1.6176
Cell Significance Index: -9.9600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -1.8471
Cell Significance Index: -49.4100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -2.0514
Cell Significance Index: -43.6900 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -2.0588
Cell Significance Index: -60.6400 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -2.1131
Cell Significance Index: -30.3500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 617492948
Symbol: RBMX_HUMAN
Name: RNA-binding motif protein, X chromosome
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7692398
Title: hnRNP G: sequence and characterization of a glycosylated RNA-binding protein.
PubMed ID: 7692398
PubMed ID: 11420617
Title: Expression and conservation of processed copies of the RBMX gene.
PubMed ID: 11420617
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10332027
Title: T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.
PubMed ID: 10332027
DOI: 10.1093/hmg/8.6.959
PubMed ID: 11991638
Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
PubMed ID: 11991638
PubMed ID: 12165565
Title: hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1.
PubMed ID: 12165565
PubMed ID: 12761049
Title: HnRNP G and Tra2beta: opposite effects on splicing matched by antagonism in RNA binding.
PubMed ID: 12761049
DOI: 10.1093/hmg/ddg136
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16707624
Title: Heterogeneous nuclear ribonucleoprotein G shows tumor suppressive effect against oral squamous cell carcinoma cells.
PubMed ID: 16707624
PubMed ID: 17890166
Title: The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G.
PubMed ID: 17890166
PubMed ID: 18445477
Title: An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release.
PubMed ID: 18445477
PubMed ID: 18541147
Title: hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip.
PubMed ID: 18541147
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19282290
Title: Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA.
PubMed ID: 19282290
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21327109
Title: Novel domains in the hnRNP G/RBMX protein with distinct roles in RNA binding and targeting nascent transcripts.
PubMed ID: 21327109
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25678563
Title: Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes.
PubMed ID: 25678563
DOI: 10.1093/brain/awv005
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25256757
Title: The RBMX gene as a candidate for the Shashi X-linked intellectual disability syndrome.
PubMed ID: 25256757
DOI: 10.1111/cge.12511
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 37277488
Title: Gustavson syndrome is caused by an in-frame deletion in RBMX associated with potentially disturbed SH3 domain interactions.
PubMed ID: 37277488
Sequence Information:
- Length: 391
- Mass: 42332
- Checksum: 904FEB9BFC573546
- Sequence:
MVEADRPGKL FIGGLNTETN EKALEAVFGK YGRIVEVLLM KDRETNKSRG FAFVTFESPA DAKDAARDMN GKSLDGKAIK VEQATKPSFE SGRRGPPPPP RSRGPPRGLR GGRGGSGGTR GPPSRGGHMD DGGYSMNFNM SSSRGPLPVK RGPPPRSGGP PPKRSAPSGP VRSSSGMGGR APVSRGRDSY GGPPRREPLP SRRDVYLSPR DDGYSTKDSY SSRDYPSSRD TRDYAPPPRD YTYRDYGHSS SRDDYPSRGY SDRDGYGRDR DYSDHPSGGS YRDSYESYGN SRSAPPTRGP PPSYGGSSRY DDYSSSRDGY GGSRDSYSSS RSDLYSSGRD RVGRQERGLP PSMERGYPPP RDSYSSSSRG APRGGGRGGS RSDRGGGRSR Y
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.