Details for: EIF3K
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 578.8027
Cell Significance Index: -90.0300 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 312.0785
Cell Significance Index: -128.5600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 301.4074
Cell Significance Index: -76.4500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 261.0550
Cell Significance Index: -123.2500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 252.6900
Cell Significance Index: -129.9800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 184.4350
Cell Significance Index: -123.7600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 87.4889
Cell Significance Index: -107.8700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 29.8603
Cell Significance Index: -117.8300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 29.5072
Cell Significance Index: -90.6300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 20.8895
Cell Significance Index: -55.9600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 18.7518
Cell Significance Index: -41.0400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 5.2127
Cell Significance Index: 243.0400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 4.8259
Cell Significance Index: 141.7300 - Cell Name: peg cell (CL4033014)
Fold Change: 4.6718
Cell Significance Index: 107.9400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 4.3821
Cell Significance Index: 205.9600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 4.0720
Cell Significance Index: 287.9900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 3.9991
Cell Significance Index: 258.0000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 3.8005
Cell Significance Index: 521.9200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.5751
Cell Significance Index: 97.3100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 3.5488
Cell Significance Index: 436.3600 - Cell Name: lactocyte (CL0002325)
Fold Change: 3.5149
Cell Significance Index: 454.1100 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 3.5016
Cell Significance Index: 39.7800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 3.4530
Cell Significance Index: 622.4800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 3.3886
Cell Significance Index: 1498.1600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 3.3330
Cell Significance Index: 393.0600 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 2.8616
Cell Significance Index: 52.8900 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.8193
Cell Significance Index: 49.8200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 2.6842
Cell Significance Index: 56.1900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.6457
Cell Significance Index: 197.1900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.5841
Cell Significance Index: 1411.2500 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.2160
Cell Significance Index: 58.2700 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 2.0678
Cell Significance Index: 22.4800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.7826
Cell Significance Index: 51.1000 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.7650
Cell Significance Index: 226.2600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.7412
Cell Significance Index: 90.4500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.5574
Cell Significance Index: 54.1200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.3642
Cell Significance Index: 232.9500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.0126
Cell Significance Index: 9.3300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.9768
Cell Significance Index: 28.1400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.9592
Cell Significance Index: 192.4200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.6284
Cell Significance Index: 16.7800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.5856
Cell Significance Index: 7.5000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5758
Cell Significance Index: 109.5700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5278
Cell Significance Index: 189.3100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.4789
Cell Significance Index: 351.1200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3111
Cell Significance Index: 19.6100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.2018
Cell Significance Index: 152.7700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0672
Cell Significance Index: 1.1300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0656
Cell Significance Index: 13.0100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0568
Cell Significance Index: 5.6200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0347
Cell Significance Index: 1.7500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0224
Cell Significance Index: 42.0900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0067
Cell Significance Index: -0.6800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0201
Cell Significance Index: -37.0500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0324
Cell Significance Index: -1.4700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0439
Cell Significance Index: -32.5500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0486
Cell Significance Index: -2.5500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0536
Cell Significance Index: -82.4500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: -0.0758
Cell Significance Index: -68.4100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0866
Cell Significance Index: -54.0800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0928
Cell Significance Index: -126.1200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.1230
Cell Significance Index: -78.1300 - Cell Name: kidney cell (CL1000497)
Fold Change: -0.1340
Cell Significance Index: -1.0700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1434
Cell Significance Index: -80.8800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1527
Cell Significance Index: -11.7200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1815
Cell Significance Index: -82.3800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1865
Cell Significance Index: -14.7700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2485
Cell Significance Index: -52.3500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3011
Cell Significance Index: -34.5000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.3305
Cell Significance Index: -3.9400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3591
Cell Significance Index: -103.3300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.4408
Cell Significance Index: -15.4900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.4686
Cell Significance Index: -76.2200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.4875
Cell Significance Index: -12.4600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.5274
Cell Significance Index: -14.7400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5718
Cell Significance Index: -66.6400 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.5883
Cell Significance Index: -8.6900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.6019
Cell Significance Index: -87.5000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.7169
Cell Significance Index: -22.9600 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.7332
Cell Significance Index: -30.0400 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.8110
Cell Significance Index: -92.5800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.9241
Cell Significance Index: -20.0200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -1.0120
Cell Significance Index: -56.7900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.0692
Cell Significance Index: -111.3300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -1.1668
Cell Significance Index: -15.9200 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.4258
Cell Significance Index: -24.5800 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -1.5540
Cell Significance Index: -23.2900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.8676
Cell Significance Index: -114.5000 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -2.0881
Cell Significance Index: -17.5400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -2.2680
Cell Significance Index: -100.3200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -2.3983
Cell Significance Index: -59.9500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -2.4913
Cell Significance Index: -73.3800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -2.6183
Cell Significance Index: -44.8700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -2.6205
Cell Significance Index: -91.8000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -2.6626
Cell Significance Index: -68.4400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -2.6843
Cell Significance Index: -87.8900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -2.6851
Cell Significance Index: -101.6800 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -2.8058
Cell Significance Index: -17.2700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -2.8230
Cell Significance Index: -89.9100 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -2.8839
Cell Significance Index: -60.1500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 123615038
Symbol: EIF3K_HUMAN
Name: Muscle-specific gene M9 protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14519125
Title: Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor eIF3.
PubMed ID: 14519125
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15327989
Title: Identification of the p28 subunit of eukaryotic initiation factor 3(eIF3k) as a new interaction partner of cyclin D3.
PubMed ID: 15327989
PubMed ID: 15703437
Title: Binding of eukaryotic initiation factor 3 to ribosomal 40S subunits and its role in ribosomal dissociation and anti-association.
PubMed ID: 15703437
DOI: 10.1261/rna.7215305
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16766523
Title: Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit.
PubMed ID: 16766523
PubMed ID: 17581632
Title: Reconstitution reveals the functional core of mammalian eIF3.
PubMed ID: 17581632
PubMed ID: 17322308
Title: Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.
PubMed ID: 17322308
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18599441
Title: Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.
PubMed ID: 18599441
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25849773
Title: eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.
PubMed ID: 25849773
DOI: 10.1038/nature14267
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27462815
Title: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
PubMed ID: 27462815
DOI: 10.1038/nature18954
PubMed ID: 15180986
Title: Crystal structure of human eIF3k, the first structure of eIF3 subunits.
PubMed ID: 15180986
Sequence Information:
- Length: 218
- Mass: 25060
- Checksum: 6B2CBBE8A9D1F28F
- Sequence:
MAMFEQMRAN VGKLLKGIDR YNPENLATLE RYVETQAKEN AYDLEANLAV LKLYQFNPAF FQTTVTAQIL LKALTNLPHT DFTLCKCMID QAHQEERPIR QILYLGDLLE TCHFQAFWQA LDENMDLLEG ITGFEDSVRK FICHVVGITY QHIDRWLLAE MLGDLSDSQL KVWMSKYGWS ADESGQIFIC SQEESIKPKN IVEKIDFDSV SSIMASSQ
Genular Protein ID: 2602970541
Symbol: K7ERF1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 192
- Mass: 22095
- Checksum: A000C812F72DEB86
- Sequence:
MAMFEQMRAN VGKLLKGIDR YNPENLATLE RYVETQAKEN AYDLEANLAV LKLYQFNPAF FQTTVTAQIL LKALTNLPHT DFTLCKCMID QAHQEERPIR QILYLGDLLE TCHFQAFWQA LDENMDLLEG ITGFEDSVRK YSQLKVWMSK YGWSADESGQ IFICSQEESI KPKNIVEKID FDSVSSIMAS SQ
Genular Protein ID: 3622934257
Symbol: K7EK53_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 131
- Mass: 15118
- Checksum: 3207B3DA60A4D3E9
- Sequence:
MIDQAHQEER PIRQILYLGD LLETCHFQAF WQALDENMDL LEGITGFEDS VRKFICHVVG ITYQHIDRWL LAEMLGDLSD SQLKVWMSKY GWSADESGQI FICSQEESIK PKNIVEKIDF DSVSSIMASS Q
Genular Protein ID: 520076245
Symbol: U3LUI4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 24036361
Title: The translation initiation factor 3 subunit eIF3K interacts with PML and associates with PML nuclear bodies.
PubMed ID: 24036361
Sequence Information:
- Length: 185
- Mass: 21310
- Checksum: 5EB4C694227545CF
- Sequence:
MAMFEQMRAN VGKLLKGIDR YQFNPAFFQT TVTAQILLKA LTNLPHTDFT LCKCMIDQAH QEERPIRQIL YLGDLLETCH FQAFWQTLDE NMDLLEGITG FEDSVRKFIC HVVGITYQHI DRWLLAEMLG DLSDSQLKVW MSKYGWSADE SGQIFICSQE ESIKPKNIVE KIDFDSVSSI MASSQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.