Details for: BIN1

Gene ID: 274

Symbol: BIN1

Ensembl ID: ENSG00000136717

Description: bridging integrator 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.67
    Marker Score: 6390
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 2.47
    Marker Score: 1010.5
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 2.35
    Marker Score: 851
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.18
    Marker Score: 4785.5
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.16
    Marker Score: 3758
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.12
    Marker Score: 9077
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.09
    Marker Score: 13340.5
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.08
    Marker Score: 1033
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 2.06
    Marker Score: 1570
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 2.05
    Marker Score: 20318
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.05
    Marker Score: 6466
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.02
    Marker Score: 106692.5
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 2
    Marker Score: 3643
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.96
    Marker Score: 1078
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.92
    Marker Score: 7862
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 1.92
    Marker Score: 3423
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.85
    Marker Score: 3750
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 1.84
    Marker Score: 1728
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.83
    Marker Score: 11903
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 1.83
    Marker Score: 1766
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 1.77
    Marker Score: 4315
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.77
    Marker Score: 3461
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.74
    Marker Score: 752
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.73
    Marker Score: 17841.5
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.71
    Marker Score: 6064
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.7
    Marker Score: 16003
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 1.69
    Marker Score: 4929.5
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 1.69
    Marker Score: 1580
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.68
    Marker Score: 7252
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.68
    Marker Score: 3949
  • Cell Name: B-1b B cell (CL0000821)
    Fold Change: 1.67
    Marker Score: 385
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.67
    Marker Score: 2015
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.65
    Marker Score: 4629.5
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.63
    Marker Score: 61961.5
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.63
    Marker Score: 24383
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 1.6
    Marker Score: 1404
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 1.6
    Marker Score: 2350
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.58
    Marker Score: 96865.5
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 1.56
    Marker Score: 1145
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.56
    Marker Score: 2952
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 1.56
    Marker Score: 512.5
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.55
    Marker Score: 1133
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.54
    Marker Score: 770
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.53
    Marker Score: 456
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.53
    Marker Score: 11703
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.53
    Marker Score: 919
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.52
    Marker Score: 55960
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.5
    Marker Score: 12892.5
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 1.49
    Marker Score: 1330
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.46
    Marker Score: 1835
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.46
    Marker Score: 2016
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 1.46
    Marker Score: 1103
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.45
    Marker Score: 3631
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 1.45
    Marker Score: 505
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 1.44
    Marker Score: 1597.5
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 1.43
    Marker Score: 1601
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 1.42
    Marker Score: 2433
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 1.42
    Marker Score: 815
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.41
    Marker Score: 28066
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 1.4
    Marker Score: 1508
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.4
    Marker Score: 2155
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 1.39
    Marker Score: 814
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.39
    Marker Score: 15643
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.38
    Marker Score: 2321
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 1.38
    Marker Score: 651
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 1.37
    Marker Score: 1221
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.37
    Marker Score: 914
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 1.37
    Marker Score: 484
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.36
    Marker Score: 15833.5
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.36
    Marker Score: 13759
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.35
    Marker Score: 12803.5
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.35
    Marker Score: 5208
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.33
    Marker Score: 1343
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.32
    Marker Score: 1303
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 1.32
    Marker Score: 1408
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.31
    Marker Score: 2744
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.31
    Marker Score: 5423
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 1.29
    Marker Score: 392
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 1.29
    Marker Score: 1086
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.28
    Marker Score: 43668
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.28
    Marker Score: 3655
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 1.28
    Marker Score: 1048
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.28
    Marker Score: 1805
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 1.25
    Marker Score: 731
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.25
    Marker Score: 828
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 1.25
    Marker Score: 825
  • Cell Name: ILC1, human (CL0001077)
    Fold Change: 1.24
    Marker Score: 314
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 1.23
    Marker Score: 414
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.2
    Marker Score: 1445
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.19
    Marker Score: 1117
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.18
    Marker Score: 3368
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 1.18
    Marker Score: 577
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 1.17
    Marker Score: 648
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.17
    Marker Score: 378
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 1.17
    Marker Score: 1107
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.17
    Marker Score: 848
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.17
    Marker Score: 336
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.16
    Marker Score: 1782
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.16
    Marker Score: 1247
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.16
    Marker Score: 246

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Other Information

**Key characteristics**: * Gene Name: BIN1 * Ensembl ID: ENSG00000136717 * Protein: BIN1_HUMAN * Protein function: Bridging integrator 1 * Pathway/Ontology: Actin filament binding, Aspartic-type endopeptidase inhibitor activity, Clathrin-mediated endocytosis, Clathrin binding, Cytoskeleton organization, Endocytosis, Gtpase binding, Identical protein binding, Membrane trafficking, Negative regulation of transcription by rna polymerase ii, Nucleus organization, Phospholipid binding, Protease binding, Protein-folding chaperone binding, Protein binding, Rna polymerase binding, Tau protein binding, Vesicle-mediated transport **Pathways and functions**: * BIN1 is involved in various cellular processes, including: * Actin filament binding: BIN1 physically interacts with actin filaments, which are essential for various cellular functions, including cell migration, cell adhesion, and signal transduction. * Aspartic-type endopeptidase inhibitor activity: BIN1 can inhibit the activity of aspartate proteases, which are enzymes that can damage cells and tissues. * Clathrin-mediated endocytosis: BIN1 is a key component of clathrin-mediated endocytosis, a process by which cells take in extracellular material. * Clathrin binding: BIN1 can bind to clathrin, a protein that is involved in the formation of clathrin-coated pits, which are cellular structures used for endocytosis. * Cytoskeleton organization: BIN1 is involved in the organization of the cytoskeleton, a network of cytoskeletal filaments that provides structural support and facilitates the movement of organelles and cells. * Endocytosis: BIN1 is involved in the process of endocytosis, a cellular mechanism by which cells take in extracellular material. * Gtpase binding: BIN1 can bind to GTPases, enzymes that are involved in cell signaling. * Identical protein binding: BIN1 can bind to an identical protein called B7Z2, which is also involved in cell signaling. * Membrane trafficking: BIN1 is involved in the trafficking of proteins between different cellular compartments. * Negative regulation of transcription by rna polymerase ii: BIN1 can bind to RNA polymerase II and inhibit its activity, which can lead to the regulation of gene expression. * Nucleus organization: BIN1 can also regulate the organization of the nucleus, including the formation of nuclear pores and the maintenance of nuclear integrity. * Phospholipid binding: BIN1 can bind to phospholipids, which are molecules that are involved in cell signaling. * Protease binding: BIN1 can bind to proteases, enzymes that can damage cells and tissues. * Protein-folding chaperone binding: BIN1 can bind to protein-folding chaperones, proteins that help to fold and maintain proteins. * Protein binding: BIN1 can bind to various proteins, including actin, clathrin, GTPases, B7Z2, and others. * Rna polymerase binding: BIN1 can bind to RNA polymerase II, an enzyme that is involved in gene expression. * Tau protein binding: BIN1 can bind to the tau protein, a protein that is involved in the structure and function of microtubules. * Vesicle-mediated transport: BIN1 can interact with vesicles, which are small membrane-bound structures that transport materials between cells. **Clinical significance**: The BIN1 gene has been implicated in various diseases, including multiple sclerosis, cancer, and neurodegenerative disorders. In multiple sclerosis, BIN1 is expressed in oligodendrocytes, a type of cell that is affected in the development of the central nervous system. BIN1 mutations have been linked to the development of multiple sclerosis, suggesting that the protein plays an important role in the disease process. In cancer, BIN1 is expressed in various tumor cells and is involved in their proliferation, migration, and survival. BIN1 mutations have been found in a significant proportion of human cancer cases, suggesting that the protein is a potential target for cancer therapy.

Genular Protein ID: 3599018716

Symbol: BIN1_HUMAN

Name: Myc box-dependent-interacting protein 1

UniProtKB Accession Codes:

O00499 O00297 O00545 O43867 O60552 O60553 O60554 O60555 O75514 O75515 O75516 O75517 O75518 Q659B7 Q92944 Q99688

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 11 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 27 EPD 1 Ensembl 11 EvolutionaryTrace 1 ExpressionAtlas 1 GO 55 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 MoonDB 1 NCBI Taxonomy 1 NIAGADS 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 7 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 11 Pumba 1 RNAct 1 Reactome 1 RefSeq 15 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCD-2DPAGE 1 UCSC 1 UniProtKB 5 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9195986

Title: Identification and characterization of a nerve terminal-enriched amphiphysin isoform.

PubMed ID: 9195986

DOI: 10.1074/jbc.272.26.16700

PubMed ID: 9182667

Title: Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of Ranvier in brain and around T tubules in skeletal muscle.

PubMed ID: 9182667

DOI: 10.1083/jcb.137.6.1355

PubMed ID: 8782822

Title: BIN1 is a novel Myc-interacting protein with features of a tumour suppressor.

PubMed ID: 8782822

DOI: 10.1038/ng0996-69

PubMed ID: 9603201

Title: Multiple amphiphysin II splice variants display differential clathrin binding: identification of two distinct clathrin-binding sites.

PubMed ID: 9603201

DOI: 10.1046/j.1471-4159.1998.70062369.x

PubMed ID: 9223448

Title: cDNA cloning of a novel amphiphysin isoform and tissue-specific expression of its multiple splice variants.

PubMed ID: 9223448

DOI: 10.1006/bbrc.1997.6927

PubMed ID: 9395479

Title: Structural analysis of the human BIN1 gene. Evidence for tissue-specific transcriptional regulation and alternate RNA splicing.

PubMed ID: 9395479

DOI: 10.1074/jbc.272.50.31453

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 9418903

Title: A role for the putative tumor suppressor Bin1 in muscle cell differentiation.

PubMed ID: 9418903

DOI: 10.1128/mcb.18.1.566

PubMed ID: 10903846

Title: Bin2, a functionally nonredundant member of the BAR adaptor gene family.

PubMed ID: 10903846

DOI: 10.1006/geno.2000.6216

PubMed ID: 12668730

Title: Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking.

PubMed ID: 12668730

DOI: 10.1242/jcs.00403

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16530520

Title: The SH3 binding motif of HCV NS5A protein interacts with Bin1 and is important for apoptosis and infectivity.

PubMed ID: 16530520

DOI: 10.1053/j.gastro.2005.12.030

PubMed ID: 17676042

Title: Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy.

PubMed ID: 17676042

DOI: 10.1038/ng2086

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24755653

Title: Mutations in BIN1 associated with centronuclear myopathy disrupt membrane remodeling by affecting protein density and oligomerization.

PubMed ID: 24755653

DOI: 10.1371/journal.pone.0093060

PubMed ID: 27179792

Title: BIN1 regulates BACE1 intracellular trafficking and amyloid-beta production.

PubMed ID: 27179792

DOI: 10.1093/hmg/ddw146

PubMed ID: 27488240

Title: Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts.

PubMed ID: 27488240

DOI: 10.1186/s13024-016-0124-1

PubMed ID: 28893863

Title: Bin1 directly remodels actin dynamics through its BAR domain.

PubMed ID: 28893863

DOI: 10.15252/embr.201744137

PubMed ID: 20142620

Title: Phenotype of a patient with recessive centronuclear myopathy and a novel BIN1 mutation.

PubMed ID: 20142620

DOI: 10.1212/wnl.0b013e3181cef7f9

PubMed ID: 25260562

Title: Adult-onset autosomal dominant centronuclear myopathy due to BIN1 mutations.

PubMed ID: 25260562

DOI: 10.1093/brain/awu272

PubMed ID: 29950440

Title: A Roma founder BIN1 mutation causes a novel phenotype of centronuclear myopathy with rigid spine.

PubMed ID: 29950440

DOI: 10.1212/wnl.0000000000005862

Sequence Information:

  • Length: 593
  • Mass: 64699
  • Checksum: 0FF1956F0C7E3B50
  • Sequence:
    • MAEMGSKGVT AGKIASNVQK KLTRAQEKVL QKLGKADETK DEQFEQCVQN FNKQLTEGTR 
LQKDLRTYLA SVKAMHEASK KLNECLQEVY EPDWPGRDEA NKIAENNDLL WMDYHQKLVD 
QALLTMDTYL GQFPDIKSRI AKRGRKLVDY DSARHHYESL QTAKKKDEAK IAKPVSLLEK 
AAPQWCQGKL QAHLVAQTNL LRNQAEEELI KAQKVFEEMN VDLQEELPSL WNSRVGFYVN 
TFQSIAGLEE NFHKEMSKLN QNLNDVLVGL EKQHGSNTFT VKAQPSDNAP AKGNKSPSPP 
DGSPAATPEI RVNHEPEPAG GATPGATLPK SPSQLRKGPP VPPPPKHTPS KEVKQEQILS 
LFEDTFVPEI SVTTPSQFEA PGPFSEQASL LDLDFDPLPP VTSPVKAPTP SGQSIPWDLW 
EPTESPAGSL PSGEPSAAEG TFAVSWPSQT AEPGPAQPAE ASEVAGGTQP AAGAQEPGET 
AASEAASSSL PAVVVETFPA TVNGTVEGGS GAGRLDLPPG FMFKVQAQHD YTATDTDELQ 
LKAGDVVLVI PFQNPEEQDE GWLMGVKESD WNQHKELEKC RGVFPENFTE RVP

Genular Protein ID: 3497018245

Symbol: B7Z2Z2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z2Z2

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 2 GenomeRNAi 1 InterPro 7 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 470
  • Mass: 51711
  • Checksum: DC211F88681AC56B
  • Sequence:
    • MAEMGSKGVT AGKIASNVQK KLTRAQEKVL QKLGKADETK DEQFEQCVQN FNKQLTEGTR 
LQKDLRTYLA SVKAMHEASK KLNECLQEVY EPDWPGRDEA NKIAENNDLL WMDYHQKLVD 
QALLTMDTYL GQFPDIKSRI AKRGRKLVDY DSARHHYESL QTAKKKDEAK IAKPVSLLEK 
AAPQWCQGKL QAHLVAQTNL LRNQAEEELI KAQKVFEEMN VDLQEELPSL WNSRVGFYVN 
TFQSIAGLEE NFHKEMSKLN QNLNDVLVGL EKQHGSNTFT VKAQPSDNAR AKGNKSPSPP 
DGSPAATPEI RVNHEPEPAG GATPGATLPK SPSQPAEASE VAGGTQPAAG AQEPGETAAS 
EAASSSLPAV VVETFPATVN GTVEGGSGAG RLDLPPGFMF KVQAQHDYTA TDTDELQLRA 
GDVVLVIPFQ NPEEQDEGWL MGVKESDWNQ HKELEKCRGV FPENFTGRVP

Genular Protein ID: 2427542689

Symbol: Q9BTH3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9BTH3

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 GO 2 Gene3D 2 GenomeRNAi 1 IntAct 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 6 SAM 2 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 439
  • Mass: 48286
  • Checksum: 350E428C8E198136
  • Sequence:
    • MAEMGSKGVT AGKIASNVQK KLTRAQEKVL QKLGKADETK DEQFEQCVQN FNKQLTEGTR 
LQKDLRTYLA SVKAMHEASK KLNECLQEVY EPDWPGRDEA NKIAENNDLL WMDYHQKLVD 
QALLTMDTYL GQFPDIKSRI AKRGRKLVDY DSARHHYESL QTAKKKDEAK IAKAEEELIK 
AQKVFEEMNV DLQEELPSLW NSRVGFYVNT FQSIAGLEEN FHKEMSKLNQ NLNDVLVGLE 
KQHGSNTFTV KAQPSDNAPA KGNKSPSPPD GSPAATPEIR VNHEPEPAGG ATPGATLPKS 
PSQPAEASEV AGGTQPAAGA QEPGETAASE AASSSLPAVV VETFPATVNG TVEGGSGAGR 
LDLPPGFMFK VQAQHDYTAT DTDELQLRAG DVVLVIPFQN PEEQDEGWLM GVKESDWNQH 
KELEKCRGVF PENFTERVP

Genular Protein ID: 3353487358

Symbol: B7Z6Y2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z6Y2

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 2 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 385
  • Mass: 43165
  • Checksum: 291A5612A0829A4A
  • Sequence:
    • MMRKVLQKLG KADETKDEQF EQCVQNFNKQ LTEGTRLQKD LRTYLASVKA MHEASKKLNE 
CLQEVYEPDW PGRDEANKIA ENNDLLWMDY HQKLVDQALL TMDTYLGQFP DIKSRIAKRG 
RKLVDYDSAR HHYESLQTAK KKDEAKIAKA EEELIKAQKV FEEMNVDLQE ELPSLWNSRV 
GFYVNTFQSI AGLEENFHKE MSKLNQNLND VLVGLEKQHG SNTFTVKAQP SDNAPAKGNK 
SPSPPDGSPA ATPEIRVNHE PEPAGGATPG ATLPKSPSQS SLPAVVVETF PATVNGTVEG 
GSGAGRLDLP PGFMFKVQAQ HDYTATDTDE LQLKAGDVVL VIPFQNPEEQ DEGWLMGVKE 
SDWNQHKELE KCRGVFPENF TERVP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.