GPX4 | ENSG00000167468 | NCBI 2879

Details for: GPX4

Gene ID: 2879

Symbol: GPX4

Ensembl ID: ENSG00000167468

Description: glutathione peroxidase 4

Associated with

Arachidonic acid metabolism
(R-HSA-2142753)
Biosynthesis of aspirin-triggered d-series resolvins
(R-HSA-9020265)
Biosynthesis of d-series resolvins
(R-HSA-9018676)
Biosynthesis of dha-derived spms
(R-HSA-9018677)
Biosynthesis of e-series 18(r)-resolvins
(R-HSA-9023661)
Biosynthesis of e-series 18(s)-resolvins
(R-HSA-9018896)
Biosynthesis of epa-derived spms
(R-HSA-9018679)
Biosynthesis of specialized proresolving mediators (spms)
(R-HSA-9018678)
Fatty acid metabolism
(R-HSA-8978868)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Synthesis of 5-eicosatetraenoic acids
(R-HSA-2142688)
Synthesis of 12-eicosatetraenoic acid derivatives
(R-HSA-2142712)
Synthesis of 15-eicosatetraenoic acid derivatives
(R-HSA-2142770)
Arachidonic acid metabolic process
(GO:0019369)
Cellular oxidant detoxification
(GO:0098869)
Chromatin organization
(GO:0006325)
Cytosol
(GO:0005829)
Extracellular exosome
(GO:0070062)
Glutathione peroxidase activity
(GO:0004602)
Identical protein binding
(GO:0042802)
Lipoxygenase pathway
(GO:0019372)
Long-chain fatty acid biosynthetic process
(GO:0042759)
Mitochondrion
(GO:0005739)
Negative regulation of ferroptosis
(GO:0110076)
Nuclear envelope
(GO:0005635)
Nucleus
(GO:0005634)
Phospholipid-hydroperoxide glutathione peroxidase activity
(GO:0047066)
Phospholipid metabolic process
(GO:0006644)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein polymerization
(GO:0051258)
Response to estradiol
(GO:0032355)
Response to oxidative stress
(GO:0006979)
Selenium binding
(GO:0008430)
Spermatogenesis
(GO:0007283)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 4.12