Details for: GPX4

Gene ID: 2879

Symbol: GPX4

Ensembl ID: ENSG00000167468

Description: glutathione peroxidase 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 922.3041
    Cell Significance Index: -143.4600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 526.3689
    Cell Significance Index: -133.5100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 370.2655
    Cell Significance Index: -152.5300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 311.9699
    Cell Significance Index: -126.7400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 311.1586
    Cell Significance Index: -146.9100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 276.7187
    Cell Significance Index: -142.3400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 220.1306
    Cell Significance Index: -147.7100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 135.0625
    Cell Significance Index: -128.9500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 122.9160
    Cell Significance Index: -151.5500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 40.2174
    Cell Significance Index: -158.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 36.5566
    Cell Significance Index: -97.9300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 35.9537
    Cell Significance Index: -110.4300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 18.1807
    Cell Significance Index: -39.7900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 5.5310
    Cell Significance Index: 257.8800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 5.2882
    Cell Significance Index: 248.5400
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 5.0258
    Cell Significance Index: 30.9300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 4.8169
    Cell Significance Index: 340.6700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 4.5909
    Cell Significance Index: 131.6000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 4.5194
    Cell Significance Index: 2468.1400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 4.2412
    Cell Significance Index: 582.4300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 4.0278
    Cell Significance Index: 300.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 3.6757
    Cell Significance Index: 192.9900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 3.5672
    Cell Significance Index: 438.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 3.4569
    Cell Significance Index: 623.1700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 3.3810
    Cell Significance Index: 436.8000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 3.3267
    Cell Significance Index: 1470.8100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 3.2154
    Cell Significance Index: 59.4300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.9683
    Cell Significance Index: 80.8000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.4460
    Cell Significance Index: 313.5600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.0978
    Cell Significance Index: 135.3400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.5817
    Cell Significance Index: 186.5300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.4767
    Cell Significance Index: 51.3200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.2735
    Cell Significance Index: 33.4900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.2491
    Cell Significance Index: 14.1900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.1599
    Cell Significance Index: 30.9700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.1346
    Cell Significance Index: 23.7500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7132
    Cell Significance Index: 141.5400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6641
    Cell Significance Index: 65.6900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6062
    Cell Significance Index: 121.6100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4570
    Cell Significance Index: 86.9600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4417
    Cell Significance Index: 398.7900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.3863
    Cell Significance Index: 292.3700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3518
    Cell Significance Index: 126.1800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.2749
    Cell Significance Index: 201.5900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1306
    Cell Significance Index: 4.5900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1159
    Cell Significance Index: 3.4100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1003
    Cell Significance Index: 5.2100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0370
    Cell Significance Index: 69.6400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0101
    Cell Significance Index: 1.6500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0135
    Cell Significance Index: -1.3800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0445
    Cell Significance Index: -0.7500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0871
    Cell Significance Index: -160.6900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0906
    Cell Significance Index: -57.5300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.1138
    Cell Significance Index: -175.2200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1414
    Cell Significance Index: -192.2000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1428
    Cell Significance Index: -1.3200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1497
    Cell Significance Index: -9.4400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.1622
    Cell Significance Index: -120.1800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.2140
    Cell Significance Index: -148.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2398
    Cell Significance Index: -135.2500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2728
    Cell Significance Index: -123.8000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.2902
    Cell Significance Index: -181.2100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3585
    Cell Significance Index: -61.2200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.3873
    Cell Significance Index: -4.2100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3977
    Cell Significance Index: -31.5000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4469
    Cell Significance Index: -128.6000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4963
    Cell Significance Index: -25.8500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.5953
    Cell Significance Index: -10.5200
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.6293
    Cell Significance Index: -3.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.6508
    Cell Significance Index: -29.5000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.6891
    Cell Significance Index: -100.1700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.7617
    Cell Significance Index: -19.4600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.8214
    Cell Significance Index: -173.0000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.8383
    Cell Significance Index: -97.6900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.9810
    Cell Significance Index: -112.3900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.0524
    Cell Significance Index: -29.4100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.0606
    Cell Significance Index: -63.6700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.0950
    Cell Significance Index: -35.0700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.3194
    Cell Significance Index: -19.7700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.4143
    Cell Significance Index: -30.6400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -1.4695
    Cell Significance Index: -90.3200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.5131
    Cell Significance Index: -157.5500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -1.5543
    Cell Significance Index: -12.4100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.6935
    Cell Significance Index: -23.1100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.8296
    Cell Significance Index: -123.0200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -1.9136
    Cell Significance Index: -14.7500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.9159
    Cell Significance Index: -51.2500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.9514
    Cell Significance Index: -149.7500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -2.0191
    Cell Significance Index: -113.3000
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -2.0222
    Cell Significance Index: -34.8600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -2.0507
    Cell Significance Index: -125.7300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -2.1827
    Cell Significance Index: -42.6000
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -2.1950
    Cell Significance Index: -31.1900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -2.3594
    Cell Significance Index: -54.5100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -2.6469
    Cell Significance Index: -70.9300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -2.8606
    Cell Significance Index: -34.1000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.9099
    Cell Significance Index: -85.7100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -2.9561
    Cell Significance Index: -17.8600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -3.2198
    Cell Significance Index: -142.4200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -3.4562
    Cell Significance Index: -88.8400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** GPX4 is a dimeric enzyme composed of two identical subunits, each containing a selenocysteine (Sec) residue at position 46, which is critical for its catalytic activity. The enzyme is highly specific for reducing lipid hydroperoxides, including phospholipid hydroperoxides, and is also capable of reducing other oxidized compounds. GPX4 has a high Km for its substrates, indicating that it is a low-affinity enzyme, but its high Vmax values suggest that it can efficiently catalyze the reduction of lipid hydroperoxides under physiological conditions. The enzyme is also sensitive to changes in pH and temperature, which can affect its activity and stability. **Pathways and Functions** GPX4 is involved in several key pathways, including: 1. **Cellular oxidant detoxification**: GPX4 plays a crucial role in protecting cells from oxidative damage by reducing lipid hydroperoxides, which are produced during the metabolism of arachidonic acid and other polyunsaturated fatty acids. 2. **Lipid metabolism**: GPX4 is involved in the regulation of lipid metabolism, particularly in the context of the lipoxygenase pathway, which is responsible for the production of eicosanoids, including leukotrienes and resolvins. 3. **Inflammation regulation**: GPX4 has been implicated in the regulation of inflammation, particularly in the context of the resolution of inflammation, where it plays a role in the production of resolvins, which are specialized proresolving mediators (SPMs) that promote the resolution of inflammation. 4. **Spermatogenesis**: GPX4 has been shown to play a crucial role in spermatogenesis, where it is involved in the regulation of oxidative stress and the maintenance of sperm cell integrity. **Clinical Significance** GPX4 has been implicated in several clinical disorders, including: 1. **Atherosclerosis**: GPX4 has been shown to play a role in the regulation of lipid metabolism and the development of atherosclerosis, where it is involved in the production of oxidized lipids and the promotion of inflammation. 2. **Cancer**: GPX4 has been implicated in the regulation of oxidative stress and the development of cancer, where it is involved in the production of reactive oxygen species (ROS) and the promotion of tumorigenesis. 3. **Neurodegenerative diseases**: GPX4 has been shown to play a role in the regulation of oxidative stress and the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, where it is involved in the production of ROS and the promotion of neuronal damage. 4. **Respiratory diseases**: GPX4 has been implicated in the regulation of oxidative stress and the development of respiratory diseases, including chronic obstructive pulmonary disease (COPD) and asthma, where it is involved in the production of ROS and the promotion of inflammation. In conclusion, GPX4 is a critical enzyme that plays a key role in the regulation of cellular antioxidant defenses, particularly in the context of oxidative stress and inflammation. Its dysregulation has been implicated in several clinical disorders, including atherosclerosis, cancer, neurodegenerative diseases, and respiratory diseases. Further research is needed to fully understand the role of GPX4 in human health and disease.

Genular Protein ID: 4084921338

Symbol: GPX4_HUMAN

Name: N/A

UniProtKB Accession Codes:

P36969 O43381 Q6PJ59 Q9UPK2

Database IDs:

ABCD 1 AGR 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 79 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EC 2 EMBL 10 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 MoonProt 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 19 PDBsum 19 PIR 1 PIRSF 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PeroxiBase 3 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 7 RefSeq 2 Rhea 32 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8039723

Title: Cloning and sequencing of the cDNA encoding a human testis phospholipid hydroperoxide glutathione peroxidase.

PubMed ID: 8039723

DOI: 10.1016/0378-1119(94)90400-6

PubMed ID: 9705830

Title: Structural organization of the human selenium-dependent phospholipid hydroperoxide glutathione peroxidase gene (GPX4): chromosomal localization to 19p13.3.

PubMed ID: 9705830

DOI: 10.1006/bbrc.1998.9086

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11115402

Title: Evidence for the presence of phospholipid hydroperoxide glutathione peroxidase in human platelets: implications for its involvement in the regulatory network of the 12-lipoxygenase pathway of arachidonic acid metabolism.

PubMed ID: 11115402

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24439385

Title: Regulation of ferroptotic cancer cell death by GPX4.

PubMed ID: 24439385

DOI: 10.1016/j.cell.2013.12.010

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 36608588

Title: Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides.

PubMed ID: 36608588

DOI: 10.1016/j.redox.2022.102593

PubMed ID: 36828120

Title: FUNDC1 interacts with GPx4 to govern hepatic ferroptosis and fibrotic injury through a mitophagy-dependent manner.

PubMed ID: 36828120

DOI: 10.1016/j.jare.2023.02.012

PubMed ID: 17630701

Title: Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4 (GPx4).

PubMed ID: 17630701

DOI: 10.1021/bi700840d

PubMed ID: 27836545

Title: Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis.

PubMed ID: 27836545

DOI: 10.1016/j.bbrc.2016.11.035

PubMed ID: 12606444

Title: Genetic variations of gpx-4 and male infertility in humans.

PubMed ID: 12606444

DOI: 10.1095/biolreprod.102.007500

PubMed ID: 24706940

Title: Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia.

PubMed ID: 24706940

DOI: 10.1136/jmedgenet-2013-102218

Sequence Information:

  • Length: 197
  • Mass: 22175
  • Checksum: 1AE3BC7AE42FDDB1
  • Sequence:
    • MSLGRLCRLL KPALLCGALA APGLAGTMCA SRDDWRCARS MHEFSAKDID GHMVNLDKYR 
GFVCIVTNVA SQUGKTEVNY TQLVDLHARY AECGLRILAF PCNQFGKQEP GSNEEIKEFA 
AGYNVKFDMF SKICVNGDDA HPLWKWMKIQ PKGKGILGNA IKWNFTKFLI DKNGCVVKRY 
GPMEEPLVIE KDLPHYF

Genular Protein ID: 3687320844

Symbol: Q6PI42_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PI42

Database IDs:

ARBA 7 BRENDA 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 4 RuleBase 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 197
  • Mass: 22164
  • Checksum: F7556DFE719C6199
  • Sequence:
    • MSLGRLCRLL KPALLCGALA APGLAGTMCA SRDDWRCARS MHEFSAKDID GHMVNLDKYR 
GFVCIVTNVA SQXGKTEVNY TQLVDLHVRY AECGLRILAF PCNQFGKQEP GSNEEIKEFA 
AGYNVKFDMF SKICVNGDDA HPLWKWMKIQ PKGKGILGNA IKWNFTKFLI DKNGCVVKRY 
GPMEEPLVIE KDLPHYF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.