Details for: MYLIP
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 1.91
Marker Score: 591 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 1.9
Marker Score: 951 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 1.89
Marker Score: 1,482 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.75
Marker Score: 6,867 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 1.7
Marker Score: 4,771 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 1.61
Marker Score: 691 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.6
Marker Score: 692 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.55
Marker Score: 2,911 - Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 1.42
Marker Score: 4,158 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.41
Marker Score: 13,277 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.35
Marker Score: 4,987 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.34
Marker Score: 13,574 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.34
Marker Score: 308 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.33
Marker Score: 2,773 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.31
Marker Score: 890 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.27
Marker Score: 14,260 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 1.25
Marker Score: 1,055 - Cell Name: reticular cell (CL0000432)
Fold Change: 1.24
Marker Score: 453 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 1.24
Marker Score: 1,796 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 1.18
Marker Score: 2,365 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.17
Marker Score: 1,729 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 1.17
Marker Score: 5,029 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 1.15
Marker Score: 2,876 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 1.15
Marker Score: 3,641 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.15
Marker Score: 39,120 - Cell Name: immature B cell (CL0000816)
Fold Change: 1.14
Marker Score: 758 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.14
Marker Score: 1,925 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.11
Marker Score: 744 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 1.11
Marker Score: 385 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 1.11
Marker Score: 338 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 1.11
Marker Score: 260 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.1
Marker Score: 1,698 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 1.1
Marker Score: 58,124 - Cell Name: pericyte (CL0000669)
Fold Change: 1.09
Marker Score: 635 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 1.09
Marker Score: 1,182 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 1.08
Marker Score: 820 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.08
Marker Score: 1,840 - Cell Name: lymphocyte (CL0000542)
Fold Change: 1.08
Marker Score: 546 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.07
Marker Score: 256 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 1.06
Marker Score: 2,936 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 1.06
Marker Score: 208 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.06
Marker Score: 262 - Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 1.06
Marker Score: 261 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 1.04
Marker Score: 1,116 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 1.03
Marker Score: 888 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.03
Marker Score: 566 - Cell Name: podocyte (CL0000653)
Fold Change: 1.03
Marker Score: 380 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.03
Marker Score: 687 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 1.03
Marker Score: 2,327 - Cell Name: pro-B cell (CL0000826)
Fold Change: 1.02
Marker Score: 988 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.02
Marker Score: 4,401 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.02
Marker Score: 15,924 - Cell Name: oocyte (CL0000023)
Fold Change: 1.02
Marker Score: 251 - Cell Name: vasa recta ascending limb cell (CL1001131)
Fold Change: 1.01
Marker Score: 267 - Cell Name: endothelial cell (CL0000115)
Fold Change: 1.01
Marker Score: 904 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.01
Marker Score: 10,395 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 1.01
Marker Score: 302 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: 1
Marker Score: 213 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1
Marker Score: 1,050 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1
Marker Score: 939 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,587 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,810 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.99
Marker Score: 655 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 0.98
Marker Score: 5,172 - Cell Name: peptic cell (CL0000155)
Fold Change: 0.98
Marker Score: 411 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,373 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.98
Marker Score: 399 - Cell Name: ionocyte (CL0005006)
Fold Change: 0.98
Marker Score: 297 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.98
Marker Score: 4,078 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.97
Marker Score: 928 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.97
Marker Score: 979 - Cell Name: tracheobronchial smooth muscle cell (CL0019019)
Fold Change: 0.97
Marker Score: 284 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.96
Marker Score: 633 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 0.96
Marker Score: 324 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 0.95
Marker Score: 1,699 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.95
Marker Score: 6,187 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.95
Marker Score: 592 - Cell Name: basal cell (CL0000646)
Fold Change: 0.95
Marker Score: 1,224 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 0.95
Marker Score: 1,308 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.95
Marker Score: 844 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.94
Marker Score: 433 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.94
Marker Score: 9,491 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 0.94
Marker Score: 385 - Cell Name: naive T cell (CL0000898)
Fold Change: 0.94
Marker Score: 606 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 0.94
Marker Score: 298 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.94
Marker Score: 1,445 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.94
Marker Score: 974 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,378 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 0.94
Marker Score: 734 - Cell Name: group 3 innate lymphoid cell (CL0001071)
Fold Change: 0.93
Marker Score: 392 - Cell Name: mature T cell (CL0002419)
Fold Change: 0.93
Marker Score: 9,236 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.93
Marker Score: 1,092 - Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
Fold Change: 0.93
Marker Score: 209 - Cell Name: smooth muscle cell of small intestine (CL1000275)
Fold Change: 0.93
Marker Score: 243 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 478 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 0.92
Marker Score: 542 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 436 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.92
Marker Score: 258 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.92
Marker Score: 581 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.91
Marker Score: 370
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3256065672
Symbol: MYLIP_HUMAN
Name: E3 ubiquitin-protein ligase MYLIP
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10593918
Title: MIR is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.
PubMed ID: 10593918
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 15498874
Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.
PubMed ID: 15498874
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14550572
Title: Functional activities and cellular localization of the ezrin, radixin, moesin (ERM) and RING zinc finger domains in MIR.
PubMed ID: 14550572
PubMed ID: 12826659
Title: MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain.
PubMed ID: 12826659
PubMed ID: 19520913
Title: LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor.
PubMed ID: 19520913
PubMed ID: 20427281
Title: The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.
PubMed ID: 20427281
PubMed ID: 22109552
Title: FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.
PubMed ID: 22109552
PubMed ID: 21685362
Title: The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.
PubMed ID: 21685362
DOI: 10.1101/gad.2056211
Sequence Information:
- Length: 445
- Mass: 49910
- Checksum: 342E643B0532B45C
- Sequence:
MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN RISQQMDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KEALLAGHLL CSPEQAVELS ALLAQTKFGD YNQNTAKYNY EELCAKELSS ATLNSIVAKH KELEGTSQAS AEYQVLQIVS AMENYGIEWH SVRDSEGQKL LIGVGPEGIS ICKDDFSPIN RIAYPVVQMA TQSGKNVYLT VTKESGNSIV LLFKMISTRA ASGLYRAITE THAFYRCDTV TSAVMMQYSR DLKGHLASLF LNENINLGKK YVFDIKRTSK EVYDHARRAL YNAGVVDLVS RNNQSPSHSP LKSSESSMNC SSCEGLSCQQ TRVLQEKLRK LKEAMLCMVC CEEEINSTFC PCGHTVCCES CAAQLQSCPV CRSRVEHVQH VYLPTHTSLL NLTVI
Genular Protein ID: 3094889449
Symbol: Q5TIA5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
Sequence Information:
- Length: 264
- Mass: 29463
- Checksum: 50DDE3EC4DCC6A64
- Sequence:
MENYGIEWHS VRDSEGQKLL IGVGPEGISI CKDDFSPINR IAYPVVQMAT QSGKNVYLTV TKESGNSIVL LFKMISTRAA SGLYRAITET HAFYRCDTVT SAVMMQYSRD LKGHLASLFL NENINLGKKY VFDIKRTSKE VYDHARRALY NAGVVDLVSR NNQSPSHSPL KSSESSMNCS SCEGLSCQQT RVLQEKLRKL KEAMLCMVCC EEEINSTFCP CGHTVCCESC AAQLQSCPVC RSRVEHVQHV YLPTHTSLLN LTVI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.