Details for: EHD4

Gene ID: 30844

Symbol: EHD4

Ensembl ID: ENSG00000103966

Description: EH domain containing 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 167.4111
    Cell Significance Index: -26.0400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 101.9936
    Cell Significance Index: -25.8700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 66.3677
    Cell Significance Index: -27.3400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 57.3036
    Cell Significance Index: -23.2800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 50.6624
    Cell Significance Index: -26.0600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 24.5616
    Cell Significance Index: -23.4500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.1930
    Cell Significance Index: -26.1300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.1979
    Cell Significance Index: -24.6400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.1725
    Cell Significance Index: -22.0300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.6801
    Cell Significance Index: -26.3600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 4.1183
    Cell Significance Index: 213.9400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 3.7291
    Cell Significance Index: 34.3400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.6966
    Cell Significance Index: 73.4000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 2.6205
    Cell Significance Index: 29.7700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.5819
    Cell Significance Index: 45.6300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.2149
    Cell Significance Index: 30.2200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.6685
    Cell Significance Index: 300.7800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.5630
    Cell Significance Index: 23.4200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3295
    Cell Significance Index: 163.4800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.0303
    Cell Significance Index: 46.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.0178
    Cell Significance Index: 131.5000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8359
    Cell Significance Index: 64.1500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.8013
    Cell Significance Index: 59.7200
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.7533
    Cell Significance Index: 5.4100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7074
    Cell Significance Index: 638.7000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6379
    Cell Significance Index: 13.8200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.5938
    Cell Significance Index: 8.5400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5709
    Cell Significance Index: 16.4500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5578
    Cell Significance Index: 35.9900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5017
    Cell Significance Index: 54.5800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4987
    Cell Significance Index: 23.4400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4873
    Cell Significance Index: 266.1200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.4814
    Cell Significance Index: 56.7800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4647
    Cell Significance Index: 45.9700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4333
    Cell Significance Index: 70.4700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3532
    Cell Significance Index: 8.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2865
    Cell Significance Index: 56.8500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.2245
    Cell Significance Index: 4.1500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1736
    Cell Significance Index: 4.3400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1670
    Cell Significance Index: 73.8200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1625
    Cell Significance Index: 27.7500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1153
    Cell Significance Index: 4.0500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0857
    Cell Significance Index: 16.3000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0761
    Cell Significance Index: 0.4600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0610
    Cell Significance Index: 3.0800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0567
    Cell Significance Index: 39.2200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0453
    Cell Significance Index: 2.3600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0345
    Cell Significance Index: 0.5100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0268
    Cell Significance Index: 36.4600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0213
    Cell Significance Index: 39.2600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0173
    Cell Significance Index: 26.6500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0150
    Cell Significance Index: 28.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0061
    Cell Significance Index: 1.2200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0029
    Cell Significance Index: 1.8600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0096
    Cell Significance Index: -7.3000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0131
    Cell Significance Index: -1.8000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0168
    Cell Significance Index: -12.4400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0171
    Cell Significance Index: -1.2100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0179
    Cell Significance Index: -11.1900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0226
    Cell Significance Index: -10.2800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0237
    Cell Significance Index: -17.3500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0282
    Cell Significance Index: -2.8800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0362
    Cell Significance Index: -20.4200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0476
    Cell Significance Index: -1.2700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0585
    Cell Significance Index: -20.9900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0615
    Cell Significance Index: -7.8800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0726
    Cell Significance Index: -10.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0749
    Cell Significance Index: -21.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0804
    Cell Significance Index: -16.9400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0860
    Cell Significance Index: -5.4200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0926
    Cell Significance Index: -2.7200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0947
    Cell Significance Index: -11.0400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0947
    Cell Significance Index: -3.2900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1010
    Cell Significance Index: -2.1500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1094
    Cell Significance Index: -5.1000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1112
    Cell Significance Index: -12.7500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1434
    Cell Significance Index: -3.7700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1617
    Cell Significance Index: -16.8400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1923
    Cell Significance Index: -6.1600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2150
    Cell Significance Index: -24.5400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2198
    Cell Significance Index: -4.5600
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: -0.2496
    Cell Significance Index: -2.5900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2705
    Cell Significance Index: -14.2000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2779
    Cell Significance Index: -17.0400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2798
    Cell Significance Index: -7.8200
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.2820
    Cell Significance Index: -1.7500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2970
    Cell Significance Index: -23.5200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3414
    Cell Significance Index: -19.1600
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.3445
    Cell Significance Index: -4.0100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3687
    Cell Significance Index: -24.7900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3729
    Cell Significance Index: -9.9700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4091
    Cell Significance Index: -12.0500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4096
    Cell Significance Index: -4.2400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4575
    Cell Significance Index: -28.1200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4586
    Cell Significance Index: -13.1500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4775
    Cell Significance Index: -9.3200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4897
    Cell Significance Index: -10.2500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.4921
    Cell Significance Index: -8.2900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5070
    Cell Significance Index: -18.6100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5589
    Cell Significance Index: -8.2500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EHD4 is a member of the EH domain-containing protein family, which is characterized by the presence of an EH domain, a PDZ domain, and a UBA domain. The EH domain is essential for binding to specific phosphotyrosine-containing motifs, while the PDZ domain facilitates protein-protein interactions. EHD4 is primarily localized to the plasma membrane, where it regulates endocytosis and exocytosis. The protein is highly expressed in various cell types, including epithelial cells, endothelial cells, and immune cells. **Pathways and Functions:** EHD4 plays a crucial role in regulating endocytosis, a process essential for cellular homeostasis. It interacts with various proteins, including clathrin, AP-2, and dynamin, to modulate the internalization of receptors, cargo, and signaling molecules. EHD4 also influences protein trafficking, cell migration, and signaling pathways, such as the regulation of peptidyl-tyrosine phosphorylation. The protein's interactions with GTP-binding proteins, such as Rho GTPases, suggest a role in cytoskeletal dynamics and cell shape changes. **Clinical Significance:** EHD4's involvement in various cellular processes makes it a potential target for therapeutic interventions in diseases characterized by dysregulated endocytosis, such as cancer, neurodegenerative disorders, and autoimmune diseases. For instance, EHD4's role in regulating endocytosis and protein trafficking has been implicated in the progression of cancer, where it may contribute to the development of resistance to therapies. In addition, EHD4's interactions with GTP-binding proteins may be relevant to the pathogenesis of neurodegenerative diseases, such as Alzheimer's and Parkinson's. **Significantly Expressed Cells:** EHD4 is highly expressed in various cell types, including: 1. Bladder urothelial cells 2. Epithelial cells of the urethra 3. Peritubular capillary endothelial cells 4. Endothelial cells of the uterus 5. Kidney capillary endothelial cells 6. Endothelial cells of the vascular tree 7. Basal cells of prostate epithelium 8. Hofbauer cells 9. Type EC enteroendocrine cells 10. Mural cells **Conclusion:** In summary, EHD4 is a multifunctional protein involved in various cellular processes, including endocytosis, protein trafficking, and signaling pathways. Its clinical significance in diseases characterized by dysregulated endocytosis and protein trafficking makes it a potential target for therapeutic interventions. Further research is necessary to fully elucidate the role of EHD4 in human health and disease. **References:** (Not provided, as the text does not include specific references. However, a comprehensive literature review on EHD4 can be conducted to gather relevant information and cite relevant studies.) **Implications:** The identification of EHD4 as a key regulator of endocytosis and protein trafficking has significant implications for our understanding of cellular processes and disease mechanisms. Further research on EHD4's role in human health and disease can lead to the development of novel therapeutic strategies for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

Genular Protein ID: 2971769449

Symbol: EHD4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9H223 Q9HAR1 Q9NZN2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 8 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 1 ExpressionAtlas 1 GO 25 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12097419

Title: Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies.

PubMed ID: 12097419

DOI: 10.4049/jimmunol.169.2.1102

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10673336

Title: EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.

PubMed ID: 10673336

DOI: 10.1006/geno.1999.6087

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17233914

Title: Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans.

PubMed ID: 17233914

DOI: 10.1186/1471-2121-8-3

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18331452

Title: A role for EHD4 in the regulation of early endosomal transport.

PubMed ID: 18331452

DOI: 10.1111/j.1600-0854.2008.00732.x

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 541
  • Mass: 61175
  • Checksum: 72DDE551829B7BF5
  • Sequence:
    • MFSWMGRQAG GRERAGGADA VQTVTGGLRS LYLRKVLPLE EAYRFHEFHS PALEDADFEN 
KPMILLVGQY STGKTTFIRY LLEQDFPGMR IGPEPTTDSF IAVMYGETEG STPGNALVVD 
PKKPFRKLSR FGNAFLNRFM CSQLPNQVLK SISVIDSPGI LSGEKQRISR GYDFCQVLQW 
FAERVDRIIL LFDAHKLDIS DEFSEAIKAF RGQDDKIRVV LNKADQVDTQ QLMRVYGALM 
WSLGKVINTP EVLRVYIGSF WAQPLQNTDN RRLFEAEAQD LFRDIQSLPQ KAAVRKLNDL 
IKRARLAKVH AYIISYLKKE MPSVFGKENK KRELISRLPE IYIQLQREYQ ISAGDFPEVK 
AMQEQLENYD FTKFHSLKPK LIEAVDNMLS NKISPLMNLI SQEETSTPTQ LVQGGAFDGT 
TEGPFNQGYG EGAKEGADEE EWVVAKDKPV YDELFYTLSP INGKISGVNA KKEMVTSKLP 
NSVLGKIWKL ADCDCDGMLD EEEFALAKHL IKIKLDGYEL PSSLPPHLVP PSHRKSLPKA 
D

Genular Protein ID: 3928544329

Symbol: A8K9B9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K9B9

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 3 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 541
  • Mass: 61156
  • Checksum: 72DA74A32CFB7BF5
  • Sequence:
    • MFSWMGRQAG GHERAGGADA VQTVTGGLRS LYLRKVLPLE EAYRFHEFHS PALEDADFEN 
KPMILLVGQY STGKTTFIRY LLEQDFPGMR IGPEPTTDSF IAVMYGETEG STPGNALVVD 
PKKPFRKLSR FGNAFLNRFM CSQLPNQVLK SISVIDSPGI LSGEKQRISR GYDFCQVLQW 
FAERVDRIIL LFDAHKLDIS DEFSEAIKAF RGQDDKIRVV LNKADQVDTQ QLMRVYGALM 
WSLGKVINTP EVLRVYIGSF WAQPLQNTDN RRLFEAEAQD LFRDIQSLPQ KAAVRKLNDL 
IKRARLAKVH AYIISYLKKE MPSVFGKENK KRELISRLPE IYIQLQREYQ ISAGDFPEVK 
AMQEQLENYD FTKFHSLKPK LIEAVDNMLS NKISPLMNLI SQEETSTPTQ LVQGGAFDGT 
TEGPFNQGYG EGAKEGADEE EWVVAKDKPV YDELFYTLSP INGKISGVNA KKEMVTSKLP 
NSVLGKIWKL ADCDCDGMLD EEEFALAKHL IKIKLDGYEL PSSLPPHLVP PSHRKSLPKA 
D

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.