Details for: SMAD5

Gene ID: 4090

Symbol: SMAD5

Ensembl ID: ENSG00000113658

Description: SMAD family member 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 312.8993
    Cell Significance Index: -48.6700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 184.4322
    Cell Significance Index: -46.7800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 104.8668
    Cell Significance Index: -49.5100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 95.4322
    Cell Significance Index: -38.7700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 40.7649
    Cell Significance Index: -38.9200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 39.9041
    Cell Significance Index: -49.2000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.5224
    Cell Significance Index: -46.9400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.4656
    Cell Significance Index: -49.1900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.8837
    Cell Significance Index: -23.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.2412
    Cell Significance Index: 116.7400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.9904
    Cell Significance Index: 25.4900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.5793
    Cell Significance Index: 94.8100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.4798
    Cell Significance Index: 266.7600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4305
    Cell Significance Index: 283.8900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.3268
    Cell Significance Index: 182.2100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.1601
    Cell Significance Index: 142.6500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1532
    Cell Significance Index: 31.3900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.9743
    Cell Significance Index: 67.3800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9541
    Cell Significance Index: 53.5400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9276
    Cell Significance Index: 410.1100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8741
    Cell Significance Index: 313.5200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8564
    Cell Significance Index: 171.7900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7563
    Cell Significance Index: 413.0400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7555
    Cell Significance Index: 96.8600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6856
    Cell Significance Index: 19.1600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6023
    Cell Significance Index: 27.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5255
    Cell Significance Index: 24.5000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5168
    Cell Significance Index: 39.6600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.5154
    Cell Significance Index: 10.0600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4914
    Cell Significance Index: 25.5300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4894
    Cell Significance Index: 14.0300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4594
    Cell Significance Index: 32.4900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.4592
    Cell Significance Index: 7.7400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4143
    Cell Significance Index: 67.3900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3993
    Cell Significance Index: 11.5100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3561
    Cell Significance Index: 22.4500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3098
    Cell Significance Index: 214.2800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2376
    Cell Significance Index: 40.5800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2060
    Cell Significance Index: 39.2100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1973
    Cell Significance Index: 4.1300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1882
    Cell Significance Index: 20.4800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1745
    Cell Significance Index: 157.5800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1574
    Cell Significance Index: 4.1400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1463
    Cell Significance Index: 3.7600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.1010
    Cell Significance Index: 0.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0810
    Cell Significance Index: 36.7700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0728
    Cell Significance Index: 0.6700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0662
    Cell Significance Index: 7.8100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0602
    Cell Significance Index: 3.7000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0496
    Cell Significance Index: 93.3400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0295
    Cell Significance Index: 0.7900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0255
    Cell Significance Index: 16.2300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0115
    Cell Significance Index: 17.7800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0037
    Cell Significance Index: 6.7800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0031
    Cell Significance Index: 4.1700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0069
    Cell Significance Index: -5.0600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0098
    Cell Significance Index: -0.4600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0213
    Cell Significance Index: -15.7800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0413
    Cell Significance Index: -25.7800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0413
    Cell Significance Index: -31.2900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0461
    Cell Significance Index: -1.2300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0551
    Cell Significance Index: -1.9400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0609
    Cell Significance Index: -34.3200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0646
    Cell Significance Index: -6.4000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0738
    Cell Significance Index: -1.2400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0945
    Cell Significance Index: -6.1000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0983
    Cell Significance Index: -10.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1074
    Cell Significance Index: -22.6200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1285
    Cell Significance Index: -8.6400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1382
    Cell Significance Index: -39.7600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1439
    Cell Significance Index: -16.4900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1614
    Cell Significance Index: -8.1600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1650
    Cell Significance Index: -23.9800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1963
    Cell Significance Index: -4.1800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2085
    Cell Significance Index: -26.9400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2093
    Cell Significance Index: -3.0100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2299
    Cell Significance Index: -26.2400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2305
    Cell Significance Index: -26.8600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2308
    Cell Significance Index: -17.2000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3302
    Cell Significance Index: -4.5100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.3618
    Cell Significance Index: -5.3400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3658
    Cell Significance Index: -7.8200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3665
    Cell Significance Index: -7.9400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3784
    Cell Significance Index: -19.8700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4000
    Cell Significance Index: -41.6500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4003
    Cell Significance Index: -13.9100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4648
    Cell Significance Index: -36.8100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5468
    Cell Significance Index: -9.3700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.5877
    Cell Significance Index: -26.0000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6151
    Cell Significance Index: -14.2100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.6522
    Cell Significance Index: -7.7800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6893
    Cell Significance Index: -26.1000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.7034
    Cell Significance Index: -10.3900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.7094
    Cell Significance Index: -10.6900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7880
    Cell Significance Index: -48.3100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.8450
    Cell Significance Index: -9.6000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.9790
    Cell Significance Index: -23.4800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.0221
    Cell Significance Index: -25.5500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.0749
    Cell Significance Index: -39.4600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0791
    Cell Significance Index: -35.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SMAD5 is a member of the SMAD family of proteins, which are essential signaling molecules that transmit TGF-β signals from the cell surface to the nucleus. SMAD5 is characterized by its ability to interact with other SMAD proteins, such as SMAD2 and SMAD3, to form heteromeric complexes that regulate the transcription of target genes. SMAD5 is also known for its ability to bind to specific DNA sequences, allowing it to regulate the expression of genes involved in embryonic development, cell differentiation, and tissue homeostasis. **Pathways and Functions:** SMAD5 is involved in various signaling pathways, including the TGF-β signaling pathway, the BMP (bone morphogenetic protein) signaling pathway, and the Wnt/β-catenin signaling pathway. These pathways regulate a wide range of cellular processes, including embryonic development, cell differentiation, tissue homeostasis, and immune responses. In the context of embryonic development, SMAD5 is essential for regulating the expression of genes involved in embryonic pattern specification, including the specification of cell fate, tissue patterning, and organogenesis. In adult tissues, SMAD5 regulates the expression of genes involved in cell differentiation, tissue homeostasis, and immune responses. **Clinical Significance:** SMAD5 dysregulation has been implicated in various diseases, including cancer, fibrosis, and developmental disorders. In cancer, SMAD5 has been shown to act as a tumor suppressor, regulating the expression of genes involved in cell proliferation, differentiation, and apoptosis. In fibrosis, SMAD5 has been shown to regulate the expression of genes involved in tissue remodeling and repair. In developmental disorders, SMAD5 dysregulation has been implicated in disorders such as achondroplasia, a genetic disorder characterized by short stature and skeletal abnormalities. SMAD5 has also been implicated in disorders such as pulmonary fibrosis, a condition characterized by scarring of lung tissue. **Significantly Expressed Cells:** SMAD5 is expressed in a wide range of cell types, including skeletal muscle satellite stem cells, interstitial cells of the ovary, lung endothelial cells, and ciliary muscle cells. These cells are involved in various cellular processes, including cell differentiation, tissue homeostasis, and immune responses. **Proteins:** The primary protein product of the SMAD5 gene is SMAD5_HUMAN (Mothers against decapentaplegic homolog 5). This protein is a key regulator of the TGF-β signaling pathway and is involved in various cellular processes, including embryonic development, cell differentiation, tissue homeostasis, and immune responses. In conclusion, SMAD5 is a critical regulator of various cellular processes, including embryonic development, cell differentiation, tissue homeostasis, and immune responses. Its dysregulation has been implicated in various diseases, including cancer, fibrosis, and developmental disorders. Further research is needed to fully understand the role of SMAD5 in maintaining tissue homeostasis and preventing disease.

Genular Protein ID: 3828878677

Symbol: SMAD5_HUMAN

Name: Mothers against decapentaplegic homolog 5

UniProtKB Accession Codes:

Q99717 O14688 Q15798 Q9UQA1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 4 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 17 Ensembl 3 ExpressionAtlas 1 GO 43 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8673135

Title: Mad-related genes in the human.

PubMed ID: 8673135

DOI: 10.1038/ng0796-347

PubMed ID: 9288787

Title: Localization of SMAD5 and its evaluation as a candidate myeloid tumor suppressor.

PubMed ID: 9288787

PubMed ID: 9264367

Title: Smad5, a tumor suppressor candidate at 5q31.1, is hemizygously lost and not mutated in the retained allele in human leukemia cell line HL60.

PubMed ID: 9264367

DOI: 10.1038/sj.leu.2400750

PubMed ID: 9484787

Title: hSmad5 gene, a human hSmad family member: its full length cDNA, genomic structure, promoter region and mutation analysis in human tumors.

PubMed ID: 9484787

DOI: 10.1038/sj.onc.1201614

PubMed ID: 9442019

Title: Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12.

PubMed ID: 9442019

DOI: 10.1074/jbc.273.4.1872

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9759503

Title: TGF-beta signal transduction.

PubMed ID: 9759503

DOI: 10.1146/annurev.biochem.67.1.753

PubMed ID: 10647776

Title: Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.

PubMed ID: 10647776

DOI: 10.1016/s1359-6101(99)00012-x

PubMed ID: 10708948

Title: The Smad pathway.

PubMed ID: 10708948

DOI: 10.1016/s1359-6101(99)00024-6

PubMed ID: 10708949

Title: TGF-beta signaling by Smad proteins.

PubMed ID: 10708949

DOI: 10.1016/s1359-6101(99)00025-8

PubMed ID: 12370310

Title: Identification of mZnf8, a mouse Kruppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.

PubMed ID: 12370310

DOI: 10.1128/mcb.22.21.7633-7644.2002

PubMed ID: 12064918

Title: Inhibition of Smad5 in human hematopoietic progenitors blocks erythroid differentiation induced by BMP4.

PubMed ID: 12064918

DOI: 10.1006/bcmd.2002.0487

PubMed ID: 12849988

Title: Mitochondrial localization of Smad5 in a human chondrogenic cell line.

PubMed ID: 12849988

DOI: 10.1016/s0006-291x(03)01139-2

PubMed ID: 15107829

Title: Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression.

PubMed ID: 15107829

DOI: 10.1038/sj.onc.1207660

PubMed ID: 15647271

Title: The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines.

PubMed ID: 15647271

DOI: 10.1074/jbc.m411234200

PubMed ID: 16516194

Title: Hgs physically interacts with Smad5 and attenuates BMP signaling.

PubMed ID: 16516194

DOI: 10.1016/j.yexcr.2006.01.019

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25755279

Title: Nuclear export of Smads by RanBP3L regulates bone morphogenetic protein signaling and mesenchymal stem cell differentiation.

PubMed ID: 25755279

DOI: 10.1128/mcb.00121-15

PubMed ID: 28675158

Title: Smad5 acts as an intracellular pH messenger and maintains bioenergetic homeostasis.

PubMed ID: 28675158

DOI: 10.1038/cr.2017.85

PubMed ID: 33510867

Title: Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes.

PubMed ID: 33510867

DOI: 10.1016/j.csbj.2020.12.044

Sequence Information:

  • Length: 465
  • Mass: 52258
  • Checksum: 4A1FD7EC7BD06728
  • Sequence:
    • MTSMASLFSF TSPAVKRLLG WKQGDEEEKW AEKAVDALVK KLKKKKGAME ELEKALSSPG 
QPSKCVTIPR SLDGRLQVSH RKGLPHVIYC RVWRWPDLQS HHELKPLDIC EFPFGSKQKE 
VCINPYHYKR VESPVLPPVL VPRHNEFNPQ HSLLVQFRNL SHNEPHMPQN ATFPDSFHQP 
NNTPFPLSPN SPYPPSPASS TYPNSPASSG PGSPFQLPAD TPPPAYMPPD DQMGQDNSQP 
MDTSNNMIPQ IMPSISSRDV QPVAYEEPKH WCSIVYYELN NRVGEAFHAS STSVLVDGFT 
DPSNNKSRFC LGLLSNVNRN STIENTRRHI GKGVHLYYVG GEVYAECLSD SSIFVQSRNC 
NFHHGFHPTT VCKIPSSCSL KIFNNQEFAQ LLAQSVNHGF EAVYELTKMC TIRMSFVKGW 
GAEYHRQDVT STPCWIEIHL HGPLQWLDKV LTQMGSPLNP ISSVS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.