Details for: MAP2

Gene ID: 4133

Symbol: MAP2

Ensembl ID: ENSG00000078018

Description: microtubule associated protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 240.9530
    Cell Significance Index: -99.2600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 181.8553
    Cell Significance Index: -73.8800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 77.6754
    Cell Significance Index: -74.1600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.5534
    Cell Significance Index: -34.0400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 10.1394
    Cell Significance Index: 243.1700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 8.1229
    Cell Significance Index: 511.9600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 7.7036
    Cell Significance Index: 473.5000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 5.9870
    Cell Significance Index: 170.8500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 5.5553
    Cell Significance Index: 373.5400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 4.9161
    Cell Significance Index: 1763.3300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.3889
    Cell Significance Index: 246.2800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 4.2229
    Cell Significance Index: 186.7900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.9881
    Cell Significance Index: 151.0200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.4897
    Cell Significance Index: 700.0300
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 3.4666
    Cell Significance Index: 26.7200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.4615
    Cell Significance Index: 2394.1200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.2442
    Cell Significance Index: 49.1400
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 2.0473
    Cell Significance Index: 26.5500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 2.0103
    Cell Significance Index: 34.4500
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 1.6531
    Cell Significance Index: 17.2200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.3922
    Cell Significance Index: 63.1100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7033
    Cell Significance Index: 635.0500
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.4172
    Cell Significance Index: 5.5700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3087
    Cell Significance Index: 30.5400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0775
    Cell Significance Index: 4.0700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0558
    Cell Significance Index: 9.0700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0213
    Cell Significance Index: 4.0500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0159
    Cell Significance Index: -0.1900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0253
    Cell Significance Index: -0.8900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0348
    Cell Significance Index: -25.7700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0402
    Cell Significance Index: -75.6200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0448
    Cell Significance Index: -82.6500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0450
    Cell Significance Index: -28.5600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0501
    Cell Significance Index: -31.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0571
    Cell Significance Index: -77.5800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0579
    Cell Significance Index: -89.1900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1158
    Cell Significance Index: -65.3200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1164
    Cell Significance Index: -85.3400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1329
    Cell Significance Index: -58.7400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1420
    Cell Significance Index: -107.4800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1450
    Cell Significance Index: -24.7600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1656
    Cell Significance Index: -4.7700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1660
    Cell Significance Index: -75.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1769
    Cell Significance Index: -96.6300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2111
    Cell Significance Index: -44.4700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2868
    Cell Significance Index: -5.6700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2903
    Cell Significance Index: -83.5300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.3186
    Cell Significance Index: -34.6500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.3508
    Cell Significance Index: -63.2300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.3726
    Cell Significance Index: -73.9400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.4601
    Cell Significance Index: -53.6200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.4873
    Cell Significance Index: -62.4700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5448
    Cell Significance Index: -62.4200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.5478
    Cell Significance Index: -79.6300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.5512
    Cell Significance Index: -25.7000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.5577
    Cell Significance Index: -68.5700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.6094
    Cell Significance Index: -71.8700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.6483
    Cell Significance Index: -83.7600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.6554
    Cell Significance Index: -7.1400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6614
    Cell Significance Index: -17.0000
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.6695
    Cell Significance Index: -6.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.6731
    Cell Significance Index: -92.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.6968
    Cell Significance Index: -71.1800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.7010
    Cell Significance Index: -19.5900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.7668
    Cell Significance Index: -53.0300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.8685
    Cell Significance Index: -99.1400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.9213
    Cell Significance Index: -95.9300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.9365
    Cell Significance Index: -30.6600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9393
    Cell Significance Index: -57.5900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.9399
    Cell Significance Index: -48.9600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.9420
    Cell Significance Index: -13.4900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -1.0537
    Cell Significance Index: -74.5200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.0894
    Cell Significance Index: -86.2800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.0937
    Cell Significance Index: -65.6600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.1139
    Cell Significance Index: -23.8100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.1343
    Cell Significance Index: -36.1300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.1603
    Cell Significance Index: -89.0400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.2242
    Cell Significance Index: -91.2400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.2334
    Cell Significance Index: -15.3800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.2392
    Cell Significance Index: -26.3000
  • Cell Name: glioblast (CL0000030)
    Fold Change: -1.2453
    Cell Significance Index: -7.8200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.2823
    Cell Significance Index: -44.5600
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -1.3151
    Cell Significance Index: -18.3900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.3344
    Cell Significance Index: -26.7900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.3984
    Cell Significance Index: -90.2200
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.4392
    Cell Significance Index: -16.7900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.4640
    Cell Significance Index: -68.8100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.4678
    Cell Significance Index: -31.8000
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -1.6877
    Cell Significance Index: -12.2700
  • Cell Name: neuron (CL0000540)
    Fold Change: -1.7734
    Cell Significance Index: -16.8100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.8317
    Cell Significance Index: -95.1500
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -1.8353
    Cell Significance Index: -11.9400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.8594
    Cell Significance Index: -23.0600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.9244
    Cell Significance Index: -61.6400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.9340
    Cell Significance Index: -24.4100
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.9407
    Cell Significance Index: -24.4900
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -1.9693
    Cell Significance Index: -23.5500
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -2.0173
    Cell Significance Index: -20.7400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.1182
    Cell Significance Index: -74.2100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -2.3495
    Cell Significance Index: -28.4800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Microtubule binding:** MAP2 is known to bind to microtubules, stabilizing their structure and promoting their polymerization. 2. **Regulation of microtubule polymerization:** MAP2 regulates microtubule polymerization, influencing the dynamics of microtubule assembly and disassembly. 3. **Tau protein binding:** MAP2 interacts with tau protein, which is a key component of neurofibrillary tangles in Alzheimer's disease. 4. **Dendritic and axonal organization:** MAP2 plays a crucial role in regulating dendritic and axonal morphology, influencing neuronal connectivity and synaptic plasticity. **Pathways and Functions:** 1. **Microtubule cytoskeleton organization:** MAP2 regulates microtubule organization, influencing the dynamics of microtubule assembly and disassembly. 2. **Protein localization:** MAP2 regulates protein localization, facilitating the transport of proteins and organelles along microtubules. 3. **Regulation of microtubule polymerization:** MAP2 regulates microtubule polymerization, influencing the dynamics of microtubule assembly and disassembly. 4. **Neurotransmitter transport:** MAP2 regulates the transport of neurotransmitters and synaptic vesicles, influencing synaptic transmission and plasticity. **Clinical Significance:** 1. **Neurodegenerative diseases:** MAP2 dysregulation has been implicated in neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 2. **Neurodevelopmental disorders:** MAP2 dysfunction has been linked to neurodevelopmental disorders, such as autism spectrum disorder and schizophrenia. 3. **CNS development:** MAP2 plays a critical role in regulating neuronal development and differentiation, highlighting its importance in CNS development and patterning. 4. **Neuroprotection:** MAP2 has been shown to have neuroprotective properties, suggesting its potential as a therapeutic target for neurodegenerative diseases. **Conclusion:** MAP2 is a multifaceted protein that plays a critical role in regulating microtubule dynamics, protein localization, and neuronal development. Its dysregulation has been implicated in various neurological disorders, highlighting its importance as a therapeutic target for neurodegenerative diseases. Further research is needed to fully elucidate the mechanisms of MAP2 function and its role in neurological disorders, but its significance in CNS development and function is already well-established.

Genular Protein ID: 1426081677

Symbol: MTAP2_HUMAN

Name: Microtubule-associated protein 2

UniProtKB Accession Codes:

P11137 Q17S04 Q8IUX2 Q99975 Q99976

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EMBL 13 Ensembl 6 ExpressionAtlas 1 GO 38 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 10 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8294038

Title: Characterization of the transcripts encoding two isoforms of human microtubule-associated protein-2 (MAP-2).

PubMed ID: 8294038

DOI: 10.1016/0378-1119(93)90502-t

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2481044

Title: Sequence of a human MAP-2 region sharing epitopes with Alzheimer neurofibrillary tangles.

PubMed ID: 2481044

DOI: 10.1002/jnr.490240405

PubMed ID: 2455776

Title: Partial sequence of MAP2 in the region of a shared epitope with Alzheimer neurofibrillary tangles.

PubMed ID: 2455776

DOI: 10.1111/j.1471-4159.1988.tb01079.x

PubMed ID: 15536091

Title: Fyn phosphorylates human MAP-2c on tyrosine 67.

PubMed ID: 15536091

DOI: 10.1074/jbc.m411380200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 33894126

Title: Missense variants in DPYSL5 cause a neurodevelopmental disorder with corpus callosum agenesis and cerebellar abnormalities.

PubMed ID: 33894126

DOI: 10.1016/j.ajhg.2021.04.004

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 1827
  • Mass: 199526
  • Checksum: 2C4801C589086603
  • Sequence:
    • MADERKDEAK APHWTSAPLT EASAHSHPPE IKDQGGAGEG LVRSANGFPY REDEEGAFGE 
HGSQGTYSNT KENGINGELT SADRETAEEV SARIVQVVTA EAVAVLKGEQ EKEAQHKDQT 
AALPLAAEET ANLPPSPPPS PASEQTVTVE EDLLTASKME FHDQQELTPS TAEPSDQKEK 
ESEKQSKPGE DLKHAALVSQ PETTKTYPDK KDMQGTEEEK APLALFGHTL VASLEDMKQK 
TEPSLVVPGI DLPKEPPTPK EQKDWFIEMP TEAKKDEWGL VAPISPGPLT PMREKDVFDD 
IPKWEGKQFD SPMPSPFQGG SFTLPLDVMK NEIVTETSPF APAFLQPDDK KSLQQTSGPA 
TAKDSFKIEE PHEAKPDKMA EAPPSEAMTL PKDAHIPVVE EHVMGKVLEE EKEAINQETV 
QQRDTFTPSG QEPILTEKET ELKLEEKTTI SDKEAVPKES KPPKPADEEI GIIQTSTEHT 
FSEQKDQEPT TDMLKQDSFP VSLEQAVTDS AMTSKTLEKA MTEPSALIEK SSIQELFEMR 
VDDKDKIEGV GAATSAELDM PFYEDKSGMS KYFETSALKE EATKSIEPGS DYYELSDTRE 
SVHESIDTMS PMHKNGDKEF QTGKESQPSP PAQEAGYSTL AQSYPSDLPE EPSSPQERMF 
TIDPKVYGEK RDLHSKNKDD LTLSRSLGLG GRSAIEQRSM SINLPMSCLD SIALGFNFGR 
GHDLSPLASD ILTNTSGSMD EGDDYLPATT PALEKAPCFP VESKEEEQIE KVKATGEEST 
QAEISCESPF LAKDFYKNGT VMAPDLPEML DLAGTRSRLA SVSADAEVAR RKSVPSETVV 
EDSRTGLPPV TDENHVIVKT DSQLEDLGYC VFNKYTVPLP SPVQDSENLS GESGTFYEGT 
DDKVRRDLAT DLSLIEVKLA AAGRVKDEFS VDKEASAHIS GDKSGLSKEF DQEKKANDRL 
DTVLEKSEEH ADSKEHAKKT EEAGDEIETF GLGVTYEQAL AKDLSIPTDA SSEKAEKGLS 
SVPEIAEVEP SKKVEQGLDF AVQGQLDVKI SDFGQMASGL NIDDRRATEL KLEATQDMTP 
SSKAPQEADA FMGVESGHMK EGTKVSETEV KEKVAKPDLV HQEAVDKEES YESSGEHESL 
TMESLKADEG KKETSPESSL IQDEIAVKLS VEIPCPPAVS EADLATDERA DVQMEFIQGP 
KEESKETPDI SITPSDVAEP LHETIVSEPA EIQSEEEEIE AQGEYDKLLF RSDTLQITDL 
GVSGAREEFV ETCPSEHKGV IESVVTIEDD FITVVQTTTD EGESGSHSVR FAALEQPEVE 
RRPSPHDEEE FEVEEAAEAQ AEPKDGSPEA PASPEREEVA LSEYKTETYD DYKDETTIDD 
SIMDADSLWV DTQDDDRSIM TEQLETIPKE EKAEKEARRS SLEKHRKEKP FKTGRGRIST 
PERKVAKKEP STVSRDEVRR KKAVYKKAEL AKKTEVQAHS PSRKFILKPA IKYTRPTHLS 
CVKRKTTAAG GESALAPSVF KQAKDKVSDG VTKSPEKRSS LPRPSSILPP RRGVSGDRDE 
NSFSLNSSIS SSARRTTRSE PIRRAGKSGT STPTTPGSTA ITPGTPPSYS SRTPGTPGTP 
SYPRTPHTPG TPKSAILVPS EKKVAIIRTP PKSPATPKQL RLINQPLPDL KNVKSKIGST 
DNIKYQPKGG QVQIVTKKID LSHVTSKCGS LKNIRHRPGG GRVKIESVKL DFKEKAQAKV 
GSLDNAHHVP GGGNVKIDSQ KLNFREHAKA RVDHGAEIIT QSPGRSSVAS PRRLSNVSSS 
GSINLLESPQ LATLAEDVTA ALAKQGL

Genular Protein ID: 2837595150

Symbol: Q6NYC5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6NYC5

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1064
  • Mass: 116420
  • Checksum: 2430DF8F0916426E
  • Sequence:
    • MADERKDEAK APHWTSAPLT EASAHSHPPE IKDQGGAGEG LVRSANGFPY REDEEGAFGE 
HGSQGTYSNT KENGINGELT SADRETAEEV SARIVQVVTA EAVAVLKGEQ EKEAQHKDQT 
AALPLAAEET ANLPPSPPPS PASEQTVTVE EDLLTASKME FHDQQELTPS TAEPSDQKEK 
ESEKQSKPGE DLKHAALVSQ PETTKTYPDK KDMQGTEEEK APLALFGHTL VASLEDMKQK 
TEPSLVVPGI DLPKEPPTPK EQKDWFIEMP TEAKKDEWGL VAPISPGPLT PMREKDVFDD 
IPKWEGKQFD SPMPSPFQGG SFTLPLDVMK NEIVTETSPF APAFLQPDDK KSLQQTSGPA 
TAKDSFKIEE PHEAKPDKMA EAPPSEAMTL PKDAHIPVVE EHVMGKVLEE EKEAINQETV 
QQRDTFTPSG QEPILTEKET ELKLEEKTTI SDKEAVPKES KPPKPADEEI GIIQTSTEHT 
FSEQKDQEPT TDMLKQDSFP VSLEQAVTDS AMTSKTLEKA MTEPSALIEK SSIQELFEMR 
VDDKDKIEGV GAATSAELDM PFYEDKSGMS KYFETSALKE EATKSIEPGS DYYELSDTRE 
SVHESIDTMS PMHKNGDKEF QTGKESQPSP PAQEAGYSTL AQSYPSDLPE EPSSPQERMF 
TIDPKVYGEK RDLHSKNKDD LTLSRSLGLG GRSAIEQRSM SINLPMSCLD SIALGFNFGR 
GHDLSPLASD ILTNTSGSMD EGDDYLPATT PALEKAPCFP VESKEEEQIE KVKATGEEST 
QAEISCESPF LAKDFYKNGT VMAPDLPEML DLAGTRSRLA SVSADAEVAR RKSVPSETVV 
EDSRTGLPPV TDENHVIVKT DSQLEDLGYC VFNKYTVPLP SPVQDSENLS GESGTFYEGT 
DDKVRRDLAT DLSLIEVKLA AAGRVKDEFS VDKEASAHIS GDKSGLSKEF DQEKKANDRL 
DTVLEKSEEH ADSKEHAKKT EEAGDEIETF RLGVTYEQAL AKDLSIPTDA SSEKAEKGLS 
SVPEIAEVEP SKKVEQGLDF AVQGQLDVKI SDFGQMASGL KKKK

Genular Protein ID: 3715988135

Symbol: A0A024R3Z1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A024R3Z1 A0A024R431

Database IDs:

BioGRID-ORCS 1 CTD 1 DisGeNET 1 EMBL 6 Ensembl 2 GO 3 GeneTree 1 HGNC 1 InterPro 3 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1858
  • Mass: 202866
  • Checksum: 86BEE214C34EDA10
  • Sequence:
    • MADERKDEAK APHWTSAPLT EASAHSHPPE IKDQGGAGEG LVRSANGFPY REDEEGAFGE 
HGSQGTYSNT KENGINGELT SADRETAEEV SARIVQVVTA EAVAVLKGEQ EKEAQHKDQT 
AALPLAAEET ANLPPSPPPS PASEQTVTVE EDLLTASKME FHDQQELTPS TAEPSDQKEK 
ESEKQSKPGE DLKHAALVSQ PETTKTYPDK KDMQGTEEEK APLALFGHTL VASLEDMKQK 
TEPSLVVPGI DLPKEPPTPK EQKDWFIEMP TEAKKDEWGL VAPISPGPLT PMREKDVFDD 
IPKWEGKQFD SPMPSPFQGG SFTLPLDVMK NEIVTETSPF APAFLQPDDK KSLQQTSGPA 
TAKDSFKIEE PHEAKPDKMA EAPPSEAMTL PKDAHIPVVE EHVMGKVLEE EKEAINQETV 
QQRDTFTPSG QEPILTEKET ELKLEEKTTI SDKEAVPKES KPPKPADEEI GIIQTSTEHT 
FSEQKDQEPT TDMLKQDSFP VSLEQAVTDS AMTSKTLEKA MTEPSALIEK SSIQELFEMR 
VDDKDKIEGV GAATSAELDM PFYEDKSGMS KYFETSALKE EATKSIEPGS DYYELSDTRE 
SVHESIDTMS PMHKNGDKEF QTGKESQPSP PAQEAGYSTL AQSYPSDLPE EPSSPQERMF 
TIDPKVYGEK RDLHSKNKDD LTLSRSLGLG GRSAIEQRSM SINLPMSCLD SIALGFNFGR 
GHDLSPLASD ILTNTSGSMD EGDDYLPATT PALEKAPCFP VESKEEEQIE KVKATGEEST 
QAEISCESPF LAKDFYKNGT VMAPDLPEML DLAGTRSRLA SVSADAEVAR RKSVPSETVV 
EDSRTGLPPV TDENHVIVKT DSQLEDLGYC VFNKYTVPLP SPVQDSENLS GESGTFYEGT 
DDKVRRDLAT DLSLIEVKLA AAGRVKDEFS VDKEASAHIS GDKSGLSKEF DQEKKANDRL 
DTVLEKSEEH ADSKEHAKKT EEAGDEIETF GLGVTYEQAL AKDLSIPTDA SSEKAEKGLS 
SVPEIAEVEP SKKVEQGLDF AVQGQLDVKI SDFGQMASGL NIDDRRATEL KLEATQDMTP 
SSKAPQEADA FMGVESGHMK EGTKVSETEV KEKVAKPDLV HQEAVDKEES YESSGEHESL 
TMESLKADEG KKETSPESSL IQDEIAVKLS VEIPCPPAVS EADLATDERA DVQMEFIQGP 
KEESKETPDI SITPSDVAEP LHETIVSEPA EIQSEEEEIE AQGEYDKLLF RSDTLQITDL 
GVSGAREEFV ETCPSEHKGV IESVVTIEDD FITVVQTTTD EGESGSHSVR FAALEQPEVE 
RRPSPHDEEE FEVEEAAEAQ AEPKDGSPEA PASPEREEVA LSEYKTETYD DYKDETTIDD 
SIMDADSLWV DTQDDDRSIM TEQLETIPKE EKAEKEARRS SLEKHRKEKP FKTGRGRIST 
PERKVAKKEP STVSRDEVRR KKAVYKKAEL AKKTEVQAHS PSRKFILKPA IKYTRPTHLS 
CVKRKTTAAG GESALAPSVF KQAKDKVSDG VTKSPEKRSS LPRPSSILPP RRGVSGDRDE 
NSFSLNSSIS SSARRTTRSE PIRRAGKSGT STPTTPGSTA ITPGTPPSYS SRTPGTPGTP 
SYPRTPHTPG TPKSAILVPS EKKVAIIRTP PKSPATPKQL RLINQPLPDL KNVKSKIGST 
DNIKYQPKGG QVRILNKKID FSKVQSRCGS KDNIKHSAGG GNVQIVTKKI DLSHVTSKCG 
SLKNIRHRPG GGRVKIESVK LDFKEKAQAK VGSLDNAHHV PGGGNVKIDS QKLNFREHAK 
ARVDHGAEII TQSPGRSSVA SPRRLSNVSS SGSINLLESP QLATLAEDVT AALAKQGL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.