Details for: MAP4
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cardiac neuron (CL0010022)
Fold Change: 5.54
Marker Score: 6,902 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 4.66
Marker Score: 11,672 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 4.6
Marker Score: 102,731 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 3.78
Marker Score: 3,268 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 3.48
Marker Score: 1,936 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 3.14
Marker Score: 4,223 - Cell Name: renal principal cell (CL0005009)
Fold Change: 3.08
Marker Score: 2,373 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 2.99
Marker Score: 1,563 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 2.92
Marker Score: 10,364 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.9
Marker Score: 5,577 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.88
Marker Score: 3,480 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.83
Marker Score: 60,412 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.82
Marker Score: 3,246 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.81
Marker Score: 11,751 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: 2.79
Marker Score: 2,125 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 2.74
Marker Score: 1,002 - Cell Name: contractile cell (CL0000183)
Fold Change: 2.71
Marker Score: 1,468 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.67
Marker Score: 5,851 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 2.62
Marker Score: 2,502 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.58
Marker Score: 1,511 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 2.55
Marker Score: 13,392 - Cell Name: mesangial cell (CL0000650)
Fold Change: 2.54
Marker Score: 3,061 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.36
Marker Score: 20,680 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.36
Marker Score: 2,668 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 2.32
Marker Score: 1,524 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.31
Marker Score: 1,382 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.31
Marker Score: 730 - Cell Name: fat cell (CL0000136)
Fold Change: 2.28
Marker Score: 1,272 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 2.27
Marker Score: 3,295 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 2.24
Marker Score: 1,182 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 2.22
Marker Score: 712 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.19
Marker Score: 10,147 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.18
Marker Score: 2,326 - Cell Name: astrocyte (CL0000127)
Fold Change: 2.17
Marker Score: 1,881 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.15
Marker Score: 627 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 2.13
Marker Score: 893 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.1
Marker Score: 2,324 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.05
Marker Score: 78,016 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 2.05
Marker Score: 1,346 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2
Marker Score: 8,356 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 2
Marker Score: 2,155 - Cell Name: podocyte (CL0000653)
Fold Change: 1.98
Marker Score: 731 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.97
Marker Score: 22,217 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.96
Marker Score: 3,992 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.95
Marker Score: 31,245 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.94
Marker Score: 14,857 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.94
Marker Score: 956 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.93
Marker Score: 7,992 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 1.92
Marker Score: 1,580 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.91
Marker Score: 487 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.91
Marker Score: 9,394 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.9
Marker Score: 19,649 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 1.89
Marker Score: 2,596 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.87
Marker Score: 2,652 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.87
Marker Score: 37,226 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.86
Marker Score: 63,443 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.86
Marker Score: 1,082 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 1.86
Marker Score: 1,398 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.85
Marker Score: 694 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.84
Marker Score: 3,459 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.84
Marker Score: 667 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 1.83
Marker Score: 694 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.83
Marker Score: 888 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.83
Marker Score: 18,370 - Cell Name: basal cell (CL0000646)
Fold Change: 1.82
Marker Score: 2,349 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.81
Marker Score: 7,007 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.8
Marker Score: 2,536 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.79
Marker Score: 4,289 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.79
Marker Score: 65,911 - Cell Name: fast muscle cell (CL0000190)
Fold Change: 1.78
Marker Score: 538 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.78
Marker Score: 26,638 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.78
Marker Score: 60,147 - Cell Name: hepatoblast (CL0005026)
Fold Change: 1.78
Marker Score: 5,826 - Cell Name: preosteoblast (CL0007010)
Fold Change: 1.75
Marker Score: 495 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.74
Marker Score: 3,087 - Cell Name: endothelial cell (CL0000115)
Fold Change: 1.74
Marker Score: 1,559 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 1.73
Marker Score: 449 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.73
Marker Score: 968 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.72
Marker Score: 14,779 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.72
Marker Score: 2,473 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.71
Marker Score: 1,925 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.7
Marker Score: 1,512 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 1.7
Marker Score: 1,118 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.69
Marker Score: 4,594 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 1.68
Marker Score: 4,246 - Cell Name: neuron (CL0000540)
Fold Change: 1.68
Marker Score: 6,850 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.68
Marker Score: 1,587 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.68
Marker Score: 1,582 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.68
Marker Score: 1,767 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.68
Marker Score: 1,182 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.67
Marker Score: 631 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.67
Marker Score: 2,018 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.66
Marker Score: 453 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.64
Marker Score: 1,744 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.64
Marker Score: 1,508 - Cell Name: pericyte (CL0000669)
Fold Change: 1.63
Marker Score: 950 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.62
Marker Score: 99,826 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 1.62
Marker Score: 544 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.62
Marker Score: 5,747 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.62
Marker Score: 466
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3841448485
Symbol: MAP4_HUMAN
Name: Microtubule-associated protein 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1718985
Title: A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences.
PubMed ID: 1718985
PubMed ID: 7857940
Title: Differential expression of alternatively spliced forms of MAP4: a repertoire of structurally different microtubule-binding domains.
PubMed ID: 7857940
DOI: 10.1021/bi00007a025
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1905296
Title: Non-neuronal 210 x 10(3) Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau.
PubMed ID: 1905296
DOI: 10.1242/jcs.98.1.27
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 10791892
Title: Ser787 in the proline-rich region of human MAP4 is a critical phosphorylation site that reduces its activity to promote tubulin polymerization.
PubMed ID: 10791892
DOI: 10.1247/csf.25.33
PubMed ID: 15144186
Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.
PubMed ID: 15144186
DOI: 10.1021/ac035352d
PubMed ID: 14759258
PubMed ID: 16093351
Title: Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4.
PubMed ID: 16093351
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17487921
Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.
PubMed ID: 17487921
PubMed ID: 17924679
Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
PubMed ID: 17924679
DOI: 10.1021/pr070152u
PubMed ID: 17693683
Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.
PubMed ID: 17693683
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 29180244
Title: Dual loss of p110delta PI3-kinase and SKAP (KNSTRN) expression leads to combined immunodeficiency and multisystem syndromic features.
PubMed ID: 29180244
PubMed ID: 34782749
Title: Regulators of tubulin polyglutamylation control nuclear shape and cilium disassembly by balancing microtubule and actin assembly.
PubMed ID: 34782749
Sequence Information:
- Length: 1152
- Mass: 121005
- Checksum: 061A69AC18593339
- Sequence:
MADLSLADAL TEPSPDIEGE IKRDFIATLE AEAFDDVVGE TVGKTDYIPL LDVDEKTGNS ESKKKPCSET SQIEDTPSSK PTLLANGGHG VEGSDTTGSP TEFLEEKMAY QEYPNSQNWP EDTNFCFQPE QVVDPIQTDP FKMYHDDDLA DLVFPSSATA DTSIFAGQND PLKDSYGMSP CNTAVVPQGW SVEALNSPHS ESFVSPEAVA EPPQPTAVPL ELAKEIEMAS EERPPAQALE IMMGLKTTDM APSKETEMAL AKDMALATKT EVALAKDMES PTKLDVTLAK DMQPSMESDM ALVKDMELPT EKEVALVKDV RWPTETDVSS AKNVVLPTET EVAPAKDVTL LKETERASPI KMDLAPSKDM GPPKENKKET ERASPIKMDL APSKDMGPPK ENKIVPAKDL VLLSEIEVAQ ANDIISSTEI SSAEKVALSS ETEVALARDM TLPPETNVIL TKDKALPLEA EVAPVKDMAQ LPETEIAPAK DVAPSTVKEV GLLKDMSPLS ETEMALGKDV TPPPETEVVL IKNVCLPPEM EVALTEDQVP ALKTEAPLAK DGVLTLANNV TPAKDVPPLS ETEATPVPIK DMEIAQTQKG ISEDSHLESL QDVGQSAAPT FMISPETVTG TGKKCSLPAE EDSVLEKLGE RKPCNSQPSE LSSETSGIAR PEEGRPVVSG TGNDITTPPN KELPPSPEKK TKPLATTQPA KTSTSKAKTQ PTSLPKQPAP TTIGGLNKKP MSLASGLVPA APPKRPAVAS ARPSILPSKD VKPKPIADAK APEKRASPSK PASAPASRSG SKSTQTVAKT TTAAAVASTG PSSRSPSTLL PKKPTAIKTE GKPAEVKKMT AKSVPADLSR PKSTSTSSMK KTTTLSGTAP AAGVVPSRVK ATPMPSRPST TPFIDKKPTS AKPSSTTPRL SRLATNTSAP DLKNVRSKVG STENIKHQPG GGRAKVEKKT EAAATTRKPE SNAVTKTAGP IASAQKQPAG KVQIVSKKVS YSHIQSKCGS KDNIKHVPGG GNVQIQNKKV DISKVSSKCG SKANIKHKPG GGDVKIESQK LNFKEKAQAK VGSLDNVGHL PAGGAVKTEG GGSEAPLCPG PPAGEEPAIS EAAPEAGAPT SASGLNGHPT LSGGGDQREA QTLDSQIQET SI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.