Details for: MCAM

Gene ID: 4162

Symbol: MCAM

Ensembl ID: ENSG00000076706

Description: melanoma cell adhesion molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 115.3982
    Cell Significance Index: -29.2700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 59.6455
    Cell Significance Index: -28.1600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.4150
    Cell Significance Index: -29.2600
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 5.4210
    Cell Significance Index: 25.0300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.3330
    Cell Significance Index: -16.3800
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 2.1246
    Cell Significance Index: 35.0100
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.7269
    Cell Significance Index: 10.7300
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.2593
    Cell Significance Index: 7.4400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.9647
    Cell Significance Index: 68.2300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.4005
    Cell Significance Index: 2.4200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.3483
    Cell Significance Index: 6.1500
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.3214
    Cell Significance Index: 2.7000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.2526
    Cell Significance Index: 2.8700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2187
    Cell Significance Index: 99.2800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.1870
    Cell Significance Index: 2.6900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1490
    Cell Significance Index: 280.5700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1408
    Cell Significance Index: 97.3700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1347
    Cell Significance Index: 59.5500
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.0919
    Cell Significance Index: 0.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0355
    Cell Significance Index: 1.9900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0298
    Cell Significance Index: 1.3900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0285
    Cell Significance Index: 10.2200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0138
    Cell Significance Index: 1.8900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.0123
    Cell Significance Index: 1.2800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0002
    Cell Significance Index: 0.0900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0010
    Cell Significance Index: -0.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0033
    Cell Significance Index: -0.4200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0093
    Cell Significance Index: -14.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0159
    Cell Significance Index: -11.7900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0167
    Cell Significance Index: -10.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0174
    Cell Significance Index: -3.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0193
    Cell Significance Index: -12.0500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0201
    Cell Significance Index: -27.3400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0206
    Cell Significance Index: -37.9200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0286
    Cell Significance Index: -5.6800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0298
    Cell Significance Index: -16.8100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0320
    Cell Significance Index: -23.4300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0397
    Cell Significance Index: -30.0400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0550
    Cell Significance Index: -4.2200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0721
    Cell Significance Index: -12.3200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0773
    Cell Significance Index: -13.9400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0797
    Cell Significance Index: -11.5900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0806
    Cell Significance Index: -23.1800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0857
    Cell Significance Index: -18.0500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1094
    Cell Significance Index: -14.1300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1470
    Cell Significance Index: -18.0800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1526
    Cell Significance Index: -7.1700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1839
    Cell Significance Index: -21.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1889
    Cell Significance Index: -19.3000
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.1956
    Cell Significance Index: -1.4100
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: -0.2028
    Cell Significance Index: -1.2700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2139
    Cell Significance Index: -25.2300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2309
    Cell Significance Index: -26.3600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2575
    Cell Significance Index: -16.6100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2611
    Cell Significance Index: -4.3700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3263
    Cell Significance Index: -25.8400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3356
    Cell Significance Index: -25.0100
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3432
    Cell Significance Index: -5.3100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.3615
    Cell Significance Index: -3.9300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3655
    Cell Significance Index: -19.0400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3851
    Cell Significance Index: -23.6700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3949
    Cell Significance Index: -19.9600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4436
    Cell Significance Index: -29.8300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4865
    Cell Significance Index: -30.6600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5057
    Cell Significance Index: -26.5500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5405
    Cell Significance Index: -33.1400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5577
    Cell Significance Index: -28.9700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5822
    Cell Significance Index: -20.2300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5905
    Cell Significance Index: -10.1200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6002
    Cell Significance Index: -26.5500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.6096
    Cell Significance Index: -27.6300
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: -0.6271
    Cell Significance Index: -3.3000
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.6306
    Cell Significance Index: -5.3600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.6311
    Cell Significance Index: -13.2100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6471
    Cell Significance Index: -22.6700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6516
    Cell Significance Index: -20.8700
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: -0.6812
    Cell Significance Index: -5.1000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7014
    Cell Significance Index: -26.5600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.7314
    Cell Significance Index: -20.4400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7382
    Cell Significance Index: -18.9800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.7797
    Cell Significance Index: -22.3500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.8112
    Cell Significance Index: -29.7800
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.8362
    Cell Significance Index: -11.4500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.8501
    Cell Significance Index: -24.9700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.8576
    Cell Significance Index: -25.2600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.8624
    Cell Significance Index: -28.2400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.8631
    Cell Significance Index: -27.4900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.8736
    Cell Significance Index: -11.0000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.8823
    Cell Significance Index: -23.5600
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.9217
    Cell Significance Index: -11.2200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.9525
    Cell Significance Index: -33.4700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9612
    Cell Significance Index: -20.4000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.9660
    Cell Significance Index: -25.8400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.9698
    Cell Significance Index: -25.5000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.9797
    Cell Significance Index: -42.6000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.9876
    Cell Significance Index: -40.4700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.9889
    Cell Significance Index: -14.6000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -1.0083
    Cell Significance Index: -31.8900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.0222
    Cell Significance Index: -27.3900
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -1.0225
    Cell Significance Index: -20.8100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MCAM is a transmembrane glycoprotein composed of three immunoglobulin-like domains, which are responsible for its cell surface binding properties. It is a member of the immunoglobulin superfamily, which includes molecules such as integrins, selectins, and cadherins. MCAM is expressed on the surface of various cell types, including pericytes, smooth muscle cells, and endothelial cells, and is involved in cell adhesion, migration, and signaling. Its expression is upregulated in response to inflammatory cytokines, growth factors, and other signaling molecules. **Pathways and Functions:** MCAM is involved in several key signaling pathways, including: 1. **Rho GTPase Cycle:** MCAM interacts with various Rho GTPases, including Rac1, Rac2, Rac3, Rhoa, Rhob, Rhoc, Rhod, Rhof, Rhog, and Rho, to regulate cell migration, cytoskeleton organization, and cell proliferation. 2. **Cell Migration:** MCAM facilitates cell migration by interacting with integrins, which are involved in the regulation of cell adhesion and migration. 3. **Angiogenesis:** MCAM is involved in the regulation of angiogenesis by interacting with endothelial cells and promoting the formation of new blood vessels. 4. **Inflammation:** MCAM is upregulated in response to inflammatory cytokines and growth factors, and is involved in the regulation of inflammatory responses. **Clinical Significance:** MCAM has been implicated in various diseases, including: 1. **Cancer:** MCAM is overexpressed in several types of cancer, including melanoma, breast cancer, and lung cancer, and is involved in tumor progression and metastasis. 2. **Cardiovascular Disease:** MCAM is involved in the regulation of vascular remodeling and is upregulated in response to cardiovascular disease. 3. **Inflammation:** MCAM is upregulated in response to inflammatory cytokines and is involved in the regulation of inflammatory responses. 4. **Neurological Disorders:** MCAM is involved in the regulation of neuronal migration and is upregulated in response to neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, MCAM is a key player in cell adhesion, migration, and angiogenesis, and its dysregulation is implicated in various diseases, including cancer, cardiovascular disease, and inflammation. Further studies are needed to fully understand the role of MCAM in these diseases and to develop therapeutic strategies to target MCAM for the treatment of these conditions. **Significantly Expressed Cells:** MCAM is expressed on the surface of various cell types, including: 1. **Renal Interstitial Pericyte:** MCAM is expressed on the surface of renal interstitial pericytes and is involved in the regulation of renal function. 2. **Kidney Interstitial Cell:** MCAM is expressed on the surface of kidney interstitial cells and is involved in the regulation of kidney function. 3. **Endocardial Cell:** MCAM is expressed on the surface of endocardial cells and is involved in the regulation of cardiac function. 4. **Supporting Cell:** MCAM is expressed on the surface of supporting cells and is involved in the regulation of tissue function. 5. **Ciliary Muscle Cell:** MCAM is expressed on the surface of ciliary muscle cells and is involved in the regulation of ocular function. 6. **Contractile Cell:** MCAM is expressed on the surface of contractile cells and is involved in the regulation of muscle function. 7. **Type EC Enteroendocrine Cell:** MCAM is expressed on the surface of type EC enteroendocrine cells and is involved in the regulation of gastrointestinal function. 8. **Smooth Muscle Cell:** MCAM is expressed on the surface of smooth muscle cells and is involved in the regulation of muscle function. **Proteins:** MCAM is composed of a single protein chain, which is composed of three immunoglobulin-like domains. The protein is involved in cell surface binding and signaling, and is upregulated in response to inflammatory cytokines and growth factors. **Ensembl ID:** The Ensembl ID for MCAM is ENSG00000076706. **Pathways/Ontology:** MCAM is involved in several key pathways, including: 1. **Anatomical structure morphogenesis** 2. **Angiogenesis** 3. **Cell adhesion** 4. **External side of plasma membrane** 5. **Extracellular region** 6. **Extracellular space** 7. **Focal adhesion** 8. **Glomerular filtration** 9. **Plasma membrane** 10. **Positive regulation of cell migration** 11. **Rac1 gtpase cycle** 12. **Rac2 gtpase cycle** 13. **Rac3 gtpase cycle** 14. **Rhoa gtpase cycle** 15. **Rhob gtpase cycle** 16. **Rhoc gtpase cycle** 17. **Rhod gtpase cycle** 18. **Rhof gtpase cycle** 19. **Rhog gtpase cycle** 20. **Rho gtpase cycle** 21. **Signaling by rho gtpases** 22. **Signal transduction** 23. **Vascular wound healing** In conclusion, MCAM is a key player in cell adhesion, migration, and angiogenesis, and its dysregulation is implicated in various diseases, including cancer, cardiovascular disease, and inflammation. Further studies are needed to fully understand the role of MCAM in these diseases and to develop therapeutic strategies to target MCAM for the treatment of these conditions.

Genular Protein ID: 2248440657

Symbol: MUC18_HUMAN

Name: Cell surface glycoprotein MUC18

UniProtKB Accession Codes:

P43121 O95812 Q59E86 Q6PHR3 Q6ZTR2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 Ensembl 1 ExpressionAtlas 1 GO 11 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 9 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2602381

Title: MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily.

PubMed ID: 2602381

DOI: 10.1073/pnas.86.24.9891

PubMed ID: 8378324

Title: Genomic organization of the melanoma-associated glycoprotein MUC18: implications for the evolution of the immunoglobulin domains.

PubMed ID: 8378324

DOI: 10.1073/pnas.90.18.8514

PubMed ID: 11709656

Title: Identification and functional assessment of endothelial P1H12.

PubMed ID: 11709656

DOI: 10.1067/mlc.2001.118519

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8162602

Title: Isolation and functional characterization of the A32 melanoma-associated antigen.

PubMed ID: 8162602

PubMed ID: 8573133

Title: Identification of the S-endo 1 endothelial-associated antigen.

PubMed ID: 8573133

DOI: 10.1006/bbrc.1996.0037

PubMed ID: 8292890

Title: The progression associated antigen MUC18: a unique member of the immunoglobulin supergene family.

PubMed ID: 8292890

DOI: 10.1097/00008390-199310000-00006

PubMed ID: 11036077

Title: Outside-in signaling pathway linked to CD146 engagement in human endothelial cells.

PubMed ID: 11036077

DOI: 10.1074/jbc.m007065200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 646
  • Mass: 71607
  • Checksum: E46CB8AC7BA0738E
  • Sequence:
    • MGLPRLVCAF LLAACCCCPR VAGVPGEAEQ PAPELVEVEV GSTALLKCGL SQSQGNLSHV 
DWFSVHKEKR TLIFRVRQGQ GQSEPGEYEQ RLSLQDRGAT LALTQVTPQD ERIFLCQGKR 
PRSQEYRIQL RVYKAPEEPN IQVNPLGIPV NSKEPEEVAT CVGRNGYPIP QVIWYKNGRP 
LKEEKNRVHI QSSQTVESSG LYTLQSILKA QLVKEDKDAQ FYCELNYRLP SGNHMKESRE 
VTVPVFYPTE KVWLEVEPVG MLKEGDRVEI RCLADGNPPP HFSISKQNPS TREAEEETTN 
DNGVLVLEPA RKEHSGRYEC QGLDLDTMIS LLSEPQELLV NYVSDVRVSP AAPERQEGSS 
LTLTCEAESS QDLEFQWLRE ETGQVLERGP VLQLHDLKRE AGGGYRCVAS VPSIPGLNRT 
QLVNVAIFGP PWMAFKERKV WVKENMVLNL SCEASGHPRP TISWNVNGTA SEQDQDPQRV 
LSTLNVLVTP ELLETGVECT ASNDLGKNTS ILFLELVNLT TLTPDSNTTT GLSTSTASPH 
TRANSTSTER KLPEPESRGV VIVAVIVCIL VLAVLGAVLY FLYKKGKLPC RRSGKQEITL 
PPSRKSELVV EVKSDKLPEE MGLLQGSSGD KRAPGDQGEK YIDLRH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.