Details for: MFGE8
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 288.0191
Cell Significance Index: -44.8000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 167.9129
Cell Significance Index: -42.5900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 85.1685
Cell Significance Index: -40.2100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 79.1617
Cell Significance Index: -32.1600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 36.3841
Cell Significance Index: -44.8600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 33.6635
Cell Significance Index: -32.1400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 14.9653
Cell Significance Index: -40.0900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 11.3899
Cell Significance Index: -44.9500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 9.9920
Cell Significance Index: -30.6900 - Cell Name: lactocyte (CL0002325)
Fold Change: 5.3821
Cell Significance Index: 695.3300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 4.5509
Cell Significance Index: 213.8900 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 3.9289
Cell Significance Index: 26.6200 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 3.2526
Cell Significance Index: 41.6600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 2.9197
Cell Significance Index: 71.2400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.7790
Cell Significance Index: 381.6400 - Cell Name: supporting cell (CL0000630)
Fold Change: 2.6901
Cell Significance Index: 12.4300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.3142
Cell Significance Index: 145.8600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.2446
Cell Significance Index: 39.6700 - Cell Name: perivascular cell (CL4033054)
Fold Change: 2.0532
Cell Significance Index: 9.4800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.0373
Cell Significance Index: 58.4000 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 1.7744
Cell Significance Index: 28.6300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.4831
Cell Significance Index: 809.9400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.1251
Cell Significance Index: 28.9200 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.0719
Cell Significance Index: 137.4100 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.0010
Cell Significance Index: 14.0400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.9560
Cell Significance Index: 33.2200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.9519
Cell Significance Index: 73.0500 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.8224
Cell Significance Index: 11.8100 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.7378
Cell Significance Index: 14.4000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6276
Cell Significance Index: 62.0900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6251
Cell Significance Index: 564.4000 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.5887
Cell Significance Index: 15.4800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5150
Cell Significance Index: 10.7800 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.4860
Cell Significance Index: 3.8800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.3624
Cell Significance Index: 5.3500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3291
Cell Significance Index: 53.5200 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.2964
Cell Significance Index: 2.4900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2823
Cell Significance Index: 56.0300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2765
Cell Significance Index: 122.2300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2653
Cell Significance Index: 50.4800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1859
Cell Significance Index: 20.2300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1361
Cell Significance Index: 61.7700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0548
Cell Significance Index: 103.1400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.0528
Cell Significance Index: 0.6300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0223
Cell Significance Index: 41.2100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0136
Cell Significance Index: 20.9200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0131
Cell Significance Index: 0.2200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0002
Cell Significance Index: -0.3000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0038
Cell Significance Index: -0.2700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0058
Cell Significance Index: -1.0400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0067
Cell Significance Index: -0.5000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0253
Cell Significance Index: -0.7300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0353
Cell Significance Index: -26.1200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0405
Cell Significance Index: -25.2700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0416
Cell Significance Index: -26.4300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0419
Cell Significance Index: -31.6800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0421
Cell Significance Index: -1.4800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0481
Cell Significance Index: -35.2700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0507
Cell Significance Index: -3.5100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0579
Cell Significance Index: -32.6500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0658
Cell Significance Index: -13.1900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0719
Cell Significance Index: -3.2600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0842
Cell Significance Index: -30.1900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.0916
Cell Significance Index: -5.5000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0980
Cell Significance Index: -11.4200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1221
Cell Significance Index: -15.0100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1336
Cell Significance Index: -38.4400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1427
Cell Significance Index: -14.5800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1512
Cell Significance Index: -25.8200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1563
Cell Significance Index: -32.9300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1638
Cell Significance Index: -9.1900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1645
Cell Significance Index: -7.6700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2358
Cell Significance Index: -34.2800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2413
Cell Significance Index: -28.4600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2647
Cell Significance Index: -17.0800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2728
Cell Significance Index: -6.9700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.3014
Cell Significance Index: -6.5300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3056
Cell Significance Index: -15.9200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3092
Cell Significance Index: -35.4200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3438
Cell Significance Index: -21.0800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3492
Cell Significance Index: -39.8600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.3880
Cell Significance Index: -19.6100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3916
Cell Significance Index: -40.7700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.4172
Cell Significance Index: -11.6600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4525
Cell Significance Index: -35.8400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4944
Cell Significance Index: -15.8400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.5004
Cell Significance Index: -30.7600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5062
Cell Significance Index: -10.7800 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.5564
Cell Significance Index: -8.4500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.6520
Cell Significance Index: -43.8400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7431
Cell Significance Index: -39.0200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.8243
Cell Significance Index: -42.8200 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.8530
Cell Significance Index: -5.3400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.8919
Cell Significance Index: -26.2000 - Cell Name: peg cell (CL4033014)
Fold Change: -0.9267
Cell Significance Index: -21.4100 - Cell Name: theca cell (CL0000503)
Fold Change: -0.9438
Cell Significance Index: -5.5500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.9469
Cell Significance Index: -34.7600 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: -0.9835
Cell Significance Index: -6.1900 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.9970
Cell Significance Index: -15.8200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.0108
Cell Significance Index: -44.7100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2806348298
Symbol: MFGM_HUMAN
Name: Lactadherin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8639264
Title: Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain.
PubMed ID: 8639264
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1909932
Title: A Mr 46,000 human milk fat globule protein that is highly expressed in human breast tumors contains factor VIII-like domains.
PubMed ID: 1909932
PubMed ID: 9535276
Title: Isolation and characterization of full and truncated forms of human breast carcinoma protein BA46 from human milk fat globule membranes.
PubMed ID: 9535276
PubMed ID: 10411933
Title: Medin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid.
PubMed ID: 10411933
PubMed ID: 9260929
Title: Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion.
PubMed ID: 9260929
PubMed ID: 18780401
Title: Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry.
PubMed ID: 18780401
PubMed ID: 19204935
Title: SED1/MFG-E8: a bi-motif protein that orchestrates diverse cellular interactions.
PubMed ID: 19204935
DOI: 10.1002/jcb.22076
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
Sequence Information:
- Length: 387
- Mass: 43105
- Checksum: 9EA357581933789D
- Sequence:
MPRPRLLAAL CGALLCAPSL LVALDICSKN PCHNGGLCEE ISQEVRGDVF PSYTCTCLKG YAGNHCETKC VEPLGLENGN IANSQIAASS VRVTFLGLQH WVPELARLNR AGMVNAWTPS SNDDNPWIQV NLLRRMWVTG VVTQGASRLA SHEYLKAFKV AYSLNGHEFD FIHDVNKKHK EFVGNWNKNA VHVNLFETPV EAQYVRLYPT SCHTACTLRF ELLGCELNGC ANPLGLKNNS IPDKQITASS SYKTWGLHLF SWNPSYARLD KQGNFNAWVA GSYGNDQWLQ VDLGSSKEVT GIITQGARNF GSVQFVASYK VAYSNDSANW TEYQDPRTGS SKIFPGNWDN HSHKKNLFET PILARYVRIL PVAWHNRIAL RLELLGC
Genular Protein ID: 764302802
Symbol: H0YKB5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
Sequence Information:
- Length: 379
- Mass: 42452
- Checksum: F729FE48A465820F
- Sequence:
MWPFPEGGNT IPILHTDICS KNPCHNGGLC EEISQEVRGD VFPSYTCTCL KGYAGNHCET KCVEPLGLEN GNIANSQIAA SSVRVTFLGL QHWVPELARL NRAGMVNAWT PSSNDDNPWI QVNLLRRMWV TGVVTQGASR LASHEYLKAF KVAYSLNGHE FDFIHDVNKK HKEFVGNWNK NAVHVNLFET PVEAQYVRLY PTSCHTACTL RFELLGCELN GCANPLGLKN NSIPDKQITA SSSYKTWGLH LFSWNPSYAR LDKQGNFNAW VAGSYGNDQW LQVDLGSSKE VTGIITQGAR NFGSVQFVAS YKVAYSNDSA NWTEYQDPRT GSSKIFPGNW DNHSHKKNLF ETPILARYVR ILPVAWHNRI ALRLELLGC
Genular Protein ID: 2390116639
Symbol: B3KTQ2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 379
- Mass: 42460
- Checksum: 46315D0D512AB1BF
- Sequence:
MWPFPEGGNT IPILHTDICS KNPCHNGGLC EEISQEVRGD VFPSYTCTCL KGYAGNHCET KCVEPLGMEN GNIANSQIAA SSVRVTFLGL QHWVPELARL NRAGMVNAWT SSSNDDNPWI QVNLLRRMWV TGVVTQGASR LASHEYLKAF KVAYSLNGHE FDFIHDVNKK HKEFVGNWNK NAVHVNLFET PVEAQYVRLY PTSCHTACTL RFELLGCELN GCANPLGLKN NSIPDKQITA SSSYKTWGLH LFSWNPSYAR LDKQGNFNAW VAGSYGNDQW LQVDLGSSKE VTGIITQGAR NFGSVQFVAS YKVAYSNDSA NWTEYQDPRT GSSKIFPGNW DNHSHKKNLF ETPILARYVR ILPVAWHNRI ALRLELLGC
Genular Protein ID: 1077221976
Symbol: B4E396_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 343
- Mass: 38405
- Checksum: DF753637EEDA74F8
- Sequence:
MPRPRLLAAL CGALLRAPSL LVALECVESL GMENGNIANS QIAASSVRVT FLGLQHWVPE LARLNRAGMV NAWTPSSNDD NPWIQVNLLR RMWVTGVVTQ GASRLASHEY LKAFKVAYSL NGHEFDFIHD VNKKHKEFVG NWNKNAVHVN LFETPVEAQY VRLYPTSCHT ACTLRFELLG CELNGCANPL GLKNNSIPDK QITASSSYKT WGLHLFSWNP SYARLDKQGN FNAWVAGSYG NDQWLQVDLG SSKEVTGIIT QGARNFGSVQ FVASYKVAYS NDSANWTEYQ DPRTGSSKIF PGNWDNHSHK KNLFETPILA RYVRILPVAW HNRIALRLEL LGC
Genular Protein ID: 2111086864
Symbol: A0A8Q3SIZ9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
Sequence Information:
- Length: 243
- Mass: 27039
- Checksum: 5802C187477E6984
- Sequence:
MPRPRLLAAL CGALLCAPSL LVALDICSKN PCHNGGLCEE ISQEVRGDVF PSYTCTCLKG YAGNHCETKC VEPLGLENGN IANSQIAASS VRVTFLGLQH WVPELARLNR AGMVNAWTPS SNDDNPWIQV NLLRRMWVTG VVTQGASRLA SHEYLKAFKV AYSLNGHEFD FIHDVNKKHK EFVGNWNKNA VHVNLFETPV EAQYVRLYPT SCHTACTLRF ELLGCELNAR KADLRRGADD REQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.