Details for: ATXN3

Gene ID: 4287

Symbol: ATXN3

Ensembl ID: ENSG00000066427

Description: ataxin 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 257.8671
    Cell Significance Index: -40.1100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 146.0712
    Cell Significance Index: -37.0500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 85.6557
    Cell Significance Index: -40.4400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 85.5370
    Cell Significance Index: -34.7500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 74.7494
    Cell Significance Index: -38.4500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 36.6067
    Cell Significance Index: -34.9500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 34.1456
    Cell Significance Index: -42.1000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.1073
    Cell Significance Index: -30.8800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.8865
    Cell Significance Index: -37.2000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.9715
    Cell Significance Index: -36.7700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.9907
    Cell Significance Index: -43.3700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.8267
    Cell Significance Index: 55.1700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 2.0639
    Cell Significance Index: 593.8400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.6709
    Cell Significance Index: 335.1900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.3111
    Cell Significance Index: 152.7900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.1730
    Cell Significance Index: 65.8200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.0298
    Cell Significance Index: 14.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8587
    Cell Significance Index: 170.4100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8330
    Cell Significance Index: 90.6000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8329
    Cell Significance Index: 135.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8134
    Cell Significance Index: 291.7700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7204
    Cell Significance Index: 43.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7020
    Cell Significance Index: 96.4000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6613
    Cell Significance Index: 18.4800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5946
    Cell Significance Index: 26.3000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5836
    Cell Significance Index: 57.7400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5792
    Cell Significance Index: 37.3700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5694
    Cell Significance Index: 102.6500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.5662
    Cell Significance Index: 21.4400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.4965
    Cell Significance Index: 7.1300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4824
    Cell Significance Index: 37.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4661
    Cell Significance Index: 57.3200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3899
    Cell Significance Index: 26.2200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3839
    Cell Significance Index: 26.5500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3759
    Cell Significance Index: 166.2000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3206
    Cell Significance Index: 175.1100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2851
    Cell Significance Index: 14.8500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2505
    Cell Significance Index: 226.2200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.2184
    Cell Significance Index: 1.4800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1878
    Cell Significance Index: 5.4100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1686
    Cell Significance Index: 317.3700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1584
    Cell Significance Index: 8.2300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1581
    Cell Significance Index: 20.2700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1553
    Cell Significance Index: 7.3000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1489
    Cell Significance Index: 6.7500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1339
    Cell Significance Index: 7.0300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1237
    Cell Significance Index: 23.5400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1135
    Cell Significance Index: 2.4600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1022
    Cell Significance Index: 64.9200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0991
    Cell Significance Index: 152.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0956
    Cell Significance Index: 176.2300
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.0855
    Cell Significance Index: 1.2300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0786
    Cell Significance Index: 35.6800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0604
    Cell Significance Index: 82.1900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0458
    Cell Significance Index: 1.5900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0373
    Cell Significance Index: 0.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0332
    Cell Significance Index: 1.5500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0309
    Cell Significance Index: 3.6500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0039
    Cell Significance Index: 0.1000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0162
    Cell Significance Index: -0.5700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0233
    Cell Significance Index: -17.1100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0257
    Cell Significance Index: -3.7400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0342
    Cell Significance Index: -2.4200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0360
    Cell Significance Index: -0.9600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0394
    Cell Significance Index: -29.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0435
    Cell Significance Index: -32.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0537
    Cell Significance Index: -6.9400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0664
    Cell Significance Index: -37.4700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0720
    Cell Significance Index: -44.9400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0863
    Cell Significance Index: -14.7300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0888
    Cell Significance Index: -9.0700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0951
    Cell Significance Index: -6.0000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1056
    Cell Significance Index: -7.8700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1741
    Cell Significance Index: -4.7400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1962
    Cell Significance Index: -22.4800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1999
    Cell Significance Index: -5.7300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2072
    Cell Significance Index: -2.4700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2081
    Cell Significance Index: -43.8300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2288
    Cell Significance Index: -5.7200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2291
    Cell Significance Index: -4.8800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2489
    Cell Significance Index: -4.1700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2946
    Cell Significance Index: -30.6800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2964
    Cell Significance Index: -6.4900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.3478
    Cell Significance Index: -4.3800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3879
    Cell Significance Index: -9.9100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4423
    Cell Significance Index: -35.0300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4564
    Cell Significance Index: -12.0000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4833
    Cell Significance Index: -2.9200
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.4957
    Cell Significance Index: -4.4000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.5166
    Cell Significance Index: -31.7500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5286
    Cell Significance Index: -16.9300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5301
    Cell Significance Index: -32.5000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.5342
    Cell Significance Index: -5.8200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.5351
    Cell Significance Index: -7.9000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.5359
    Cell Significance Index: -27.0900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.5502
    Cell Significance Index: -10.1700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5775
    Cell Significance Index: -16.4800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.6443
    Cell Significance Index: -17.2700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6743
    Cell Significance Index: -19.8600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6802
    Cell Significance Index: -15.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ATXN3 is a ubiquitin C-terminal hydrolase (UCH) that is primarily expressed in the nervous system, particularly in neurons and glial cells. The ATXN3 protein consists of 368 amino acids and contains a characteristic ubiquitin-like domain, which is essential for its enzymatic activity. The gene is highly expressed in the brain, with highest levels detected in the cerebellum, brainstem, and spinal cord. **Pathways and Functions** ATXN3 is involved in several cellular pathways that regulate protein homeostasis, including: 1. **Deubiquitination**: ATXN3 is a deubiquitinating enzyme (DUB) that removes ubiquitin chains from target proteins, thereby regulating protein degradation and turnover. 2. **Protein quality control**: ATXN3 plays a crucial role in maintaining protein quality control by regulating the degradation of misfolded or incompletely synthesized proteins. 3. **Actin cytoskeleton organization**: ATXN3 is involved in regulating the actin cytoskeleton, which is essential for maintaining cell shape and movement. 4. **Cellular response to stress**: ATXN3 is activated in response to cellular stress, including heat shock, oxidative stress, and amino acid starvation. **Clinical Significance** Mutations in the ATXN3 gene are associated with several neurodegenerative disorders, including: 1. **Spinocerebellar ataxia type 3 (SCA3)**: A rare, autosomal dominant disorder characterized by progressive ataxia, dysarthria, and dysphagia. 2. **Other ataxias**: ATXN3 mutations have also been associated with other ataxias, including spinocerebellar ataxia type 2 (SCA2) and spinocerebellar ataxia type 6 (SCA6). 3. **Frontotemporal dementia**: ATXN3 mutations have been linked to frontotemporal dementia, a group of neurodegenerative disorders characterized by progressive cognitive and motor decline. In conclusion, ATXN3 is a critical gene that plays a key role in maintaining protein homeostasis and regulating various cellular processes. Mutations in the ATXN3 gene are associated with several neurodegenerative disorders, highlighting the importance of this gene in maintaining human health. Further research is necessary to fully understand the mechanisms underlying ATXN3-related disorders and to develop effective therapeutic strategies for these diseases.

Genular Protein ID: 1370088988

Symbol: ATX3_HUMAN

Name: Ataxin-3

UniProtKB Accession Codes:

P54252 A7LFZ5 D6RDL9 E9PB63 O15284 O15285 O15286 Q8N189 Q96TC3 Q96TC4 Q9H3N0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EC 1 ELM 1 EMBL 12 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 39 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 2 RefSeq 4 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7874163

Title: CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.

PubMed ID: 7874163

DOI: 10.1038/ng1194-221

PubMed ID: 9274833

Title: Machado-Joseph disease gene products carrying different carboxyl termini.

PubMed ID: 9274833

DOI: 10.1016/s0168-0102(97)00056-4

PubMed ID: 11450850

Title: The genomic structure and expression of MJD, the Machado-Joseph disease gene.

PubMed ID: 11450850

DOI: 10.1007/s100380170060

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9580663

Title: Ataxin-3 is transported into the nucleus and associates with the nuclear matrix.

PubMed ID: 9580663

DOI: 10.1093/hmg/7.6.991

PubMed ID: 12297501

Title: Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities.

PubMed ID: 12297501

DOI: 10.1074/jbc.m205259200

PubMed ID: 17696782

Title: Josephin domain-containing proteins from a variety of species are active de-ubiquitination enzymes.

PubMed ID: 17696782

DOI: 10.1515/bc.2007.107

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23625928

Title: JosD1, a membrane-targeted deubiquitinating enzyme, is activated by ubiquitination and regulates membrane dynamics, cell motility, and endocytosis.

PubMed ID: 23625928

DOI: 10.1074/jbc.m113.463406

PubMed ID: 23696636

Title: The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.

PubMed ID: 23696636

DOI: 10.1074/jbc.c113.477596

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28445460

Title: Polyglutamine tracts regulate beclin 1-dependent autophagy.

PubMed ID: 28445460

DOI: 10.1038/nature22078

PubMed ID: 30455355

Title: Physiological and pathophysiological characteristics of ataxin-3 isoforms.

PubMed ID: 30455355

DOI: 10.1074/jbc.ra118.005801

PubMed ID: 33157014

Title: Amino acids enhance polyubiquitination of Rheb and its binding to mTORC1 by blocking lysosomal ATXN3 deubiquitinase activity.

PubMed ID: 33157014

DOI: 10.1016/j.molcel.2020.10.004

PubMed ID: 12486728

Title: Structural modeling of ataxin-3 reveals distant homology to adaptins.

PubMed ID: 12486728

DOI: 10.1002/prot.10280

PubMed ID: 16020535

Title: The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition.

PubMed ID: 16020535

DOI: 10.1073/pnas.0501732102

PubMed ID: 16118278

Title: Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain.

PubMed ID: 16118278

DOI: 10.1073/pnas.0506344102

Sequence Information:

  • Length: 361
  • Mass: 41250
  • Checksum: 90C3EF73BB26CAFD
  • Sequence:
    • MESIFHEKQE GSLCAQHCLN NLLQGEYFSP VELSSIAHQL DEEERMRMAE GGVTSEDYRT 
FLQQPSGNMD DSGFFSIQVI SNALKVWGLE LILFNSPEYQ RLRIDPINER SFICNYKEHW 
FTVRKLGKQW FNLNSLLTGP ELISDTYLAL FLAQLQQEGY SIFVVKGDLP DCEADQLLQM 
IRVQQMHRPK LIGEELAQLK EQRVHKTDLE RVLEANDGSG MLDEDEEDLQ RALALSRQEI 
DMEDEEADLR RAIQLSMQGS SRNISQDMTQ TSGTNLTSEE LRKRREAYFE KQQQKQQQQQ 
QQQQQGDLSG QSSHPCERPA TSSGALGSDL GDAMSEEDML QAAVTMSLET VRNDLKTEGK 
K

Genular Protein ID: 190834089

Symbol: A0A0A0MS38_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MS38

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 310
  • Mass: 35104
  • Checksum: 6DF4BCD59A8748C5
  • Sequence:
    • MESIFHEKQE GSLCAQHCLN NLLQGEYFSP VELSSIAHQL DEEERMRMAE GGVTSEDYRT 
FLQQPSGNMD DSGFFSIQWF NLNSLLTGPE LISDTYLALF LAQLQQEGYS IFVVKGDLPD 
CEADQLLQMI RVQQMHRPKL IGEELAQLKE QRVHKTDLER VLEANDGSGM LDEDEEDLQR 
ALALSRQEID MEDEEADLRR AIQLSMQGSS RNISQDMTQT SGTNLTSEEL RKRREAYFEK 
QQQKQQQQQQ QQQQGDLSGQ SSHPCERPAT SSGALGSDLG DAMSEEDMLQ AAVTMSLETV 
RNDLKTEGKK

Genular Protein ID: 2317014892

Symbol: C9JQV6_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9JQV6

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MEROPS 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 291
  • Mass: 33394
  • Checksum: 6DACA61967CCB544
  • Sequence:
    • MESIFHEKVI SNALKVWGLE LILFNSPEYQ RLRIDPINER SFICNYKEHW FTVRKLGKQW 
FNLNSLLTGP ELISDTYLAL FLAQLQQEGY SIFVVKGDLP DCEADQLLQM IRVQQMHRPK 
LIGEELAQLK EQRVHKTDLE RVLEANDGSG MLDEDEEDLQ RALALSRQEI DMEDEEADLR 
RAIQLSMQGS SRNISQDMTQ TSGTNLTSEE LRKRREAYFE KQQQKQQQQQ QQQQQGDLSG 
QSSHPCERPA TSSGALGSDL GDAMSEEDML QAAVTMSLET VRNDLKTEGK K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.