Details for: MLF1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 221.8647
Cell Significance Index: -34.5100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 133.5339
Cell Significance Index: -33.8700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 81.1268
Cell Significance Index: -33.4200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 71.0620
Cell Significance Index: -33.5500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 68.2080
Cell Significance Index: -27.7100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 28.7093
Cell Significance Index: -27.4100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 28.0626
Cell Significance Index: -34.6000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.0872
Cell Significance Index: -32.3800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.7138
Cell Significance Index: -34.3900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 2.2633
Cell Significance Index: 173.6800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.1848
Cell Significance Index: 137.7000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.5037
Cell Significance Index: 112.0700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.4718
Cell Significance Index: 42.1900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.3492
Cell Significance Index: 59.6800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 1.2788
Cell Significance Index: 18.8800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.2227
Cell Significance Index: 46.3000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.2188
Cell Significance Index: 665.5900 - Cell Name: germ cell (CL0000586)
Fold Change: 1.2045
Cell Significance Index: 9.1000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.1199
Cell Significance Index: 13.3500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.0182
Cell Significance Index: 46.1500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.0085
Cell Significance Index: 52.3900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.9880
Cell Significance Index: 13.4800 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.9712
Cell Significance Index: 125.4700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.9385
Cell Significance Index: 109.3700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7762
Cell Significance Index: 155.7000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7603
Cell Significance Index: 686.4600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6353
Cell Significance Index: 62.8500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.6330
Cell Significance Index: 13.2500 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 0.6141
Cell Significance Index: 1.7600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4866
Cell Significance Index: 79.1400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.4014
Cell Significance Index: 51.4600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3995
Cell Significance Index: 54.8700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.3891
Cell Significance Index: 10.5900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3640
Cell Significance Index: 160.9500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.3480
Cell Significance Index: 16.3600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3370
Cell Significance Index: 20.2300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.3277
Cell Significance Index: 5.7900 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 0.2705
Cell Significance Index: 1.6700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.2695
Cell Significance Index: 18.1200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2310
Cell Significance Index: 41.6400 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.2305
Cell Significance Index: 1.8400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.2286
Cell Significance Index: 7.9500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2168
Cell Significance Index: 5.4200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2020
Cell Significance Index: 24.8400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1718
Cell Significance Index: 61.6100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1693
Cell Significance Index: 11.7100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0980
Cell Significance Index: 1.6400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0846
Cell Significance Index: 58.4900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0835
Cell Significance Index: 15.8900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0613
Cell Significance Index: 2.8600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0531
Cell Significance Index: 1.1500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0072
Cell Significance Index: 13.4900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0042
Cell Significance Index: 0.1200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0037
Cell Significance Index: 0.1300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0072
Cell Significance Index: -0.5100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0106
Cell Significance Index: -19.4900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0110
Cell Significance Index: -8.0800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0129
Cell Significance Index: -19.9100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0132
Cell Significance Index: -6.0100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0146
Cell Significance Index: -19.9100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0281
Cell Significance Index: -21.2500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0314
Cell Significance Index: -23.2700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0315
Cell Significance Index: -20.0100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0469
Cell Significance Index: -2.4700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0477
Cell Significance Index: -4.8700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0506
Cell Significance Index: -1.3000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0523
Cell Significance Index: -29.4800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0602
Cell Significance Index: -37.5900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0636
Cell Significance Index: -12.6300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0955
Cell Significance Index: -27.4900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1059
Cell Significance Index: -6.5100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1120
Cell Significance Index: -16.2900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1156
Cell Significance Index: -3.3000 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1232
Cell Significance Index: -1.4000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1287
Cell Significance Index: -2.7500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1321
Cell Significance Index: -22.5500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1480
Cell Significance Index: -16.9600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1636
Cell Significance Index: -34.4600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1639
Cell Significance Index: -4.5800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1909
Cell Significance Index: -10.7100 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2103
Cell Significance Index: -4.8600 - Cell Name: theca cell (CL0000503)
Fold Change: -0.2136
Cell Significance Index: -1.2600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2172
Cell Significance Index: -4.2400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.2342
Cell Significance Index: -3.5100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2548
Cell Significance Index: -6.7000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2587
Cell Significance Index: -30.5100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2684
Cell Significance Index: -13.9800 - Cell Name: glioblast (CL0000030)
Fold Change: -0.2803
Cell Significance Index: -1.7600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2983
Cell Significance Index: -6.3500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3052
Cell Significance Index: -24.1700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3191
Cell Significance Index: -33.2300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3663
Cell Significance Index: -22.4600 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.4243
Cell Significance Index: -6.0400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.4471
Cell Significance Index: -13.1700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.4599
Cell Significance Index: -10.0700 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.4692
Cell Significance Index: -7.5700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5152
Cell Significance Index: -33.2400 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.5744
Cell Significance Index: -7.3700 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.5832
Cell Significance Index: -6.3400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.5907
Cell Significance Index: -15.8300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 240054257
Symbol: MLF1_HUMAN
Name: Myeloid leukemia factor 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8570204
Title: The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1.
PubMed ID: 8570204
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15116101
Title: cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP.
PubMed ID: 15116101
PubMed ID: 15861129
Title: Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3.
PubMed ID: 15861129
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 22151054
Title: Structural insights of the MLF1/14-3-3 interaction.
PubMed ID: 22151054
Sequence Information:
- Length: 268
- Mass: 30627
- Checksum: 08774217329F737A
- Sequence:
MFRMLNSSFE DDPFFSESIL AHRENMRQMI RSFSEPFGRD LLSISDGRGR AHNRRGHNDG EDSLTHTDVS SFQTMDQMVS NMRNYMQKLE RNFGQLSVDP NGHSFCSSSV MTYSKIGDEP PKVFQASTQT RRAPGGIKET RKAMRDSDSG LEKMAIGHHI HDRAHVIKKS KNKKTGDEEV NQEFINMNES DAHAFDEEWQ SEVLKYKPGR HNLGNTRMRS VGHENPGSRE LKRREKPQQS PAIEHGRRSN VLGDKLHIKG SSVKSNKK
Genular Protein ID: 2277235006
Symbol: Q5HYH4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 256
- Mass: 28808
- Checksum: 63B188D3DFA82062
- Sequence:
MRQMIRSFSE PFGRDLLSIS DGRGRAHNRR GHNDGEDSLT ATSCSLVPFG DFGHTDVSSF QTMDQMVSNM RNYMQKLERN FGQLSVDPNG HSFCSSSVMT YSKIGDEPPK VFQASTQTRR APGGIKETRK AMRDSDSGLE KMAIGHHIHD RAHVIKKSKN KKTGDEEVNQ EFINMNESDA HAFDEEWQSE VLKYKPGRHN LGNTRMRSVG HENPGSRELK RGEKPQQSPA IEHGRRSNVL GDKLHIKGSS VKSNKK
Genular Protein ID: 3199779746
Symbol: A0A140VKD2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 243
- Mass: 27625
- Checksum: 061E87A385C3E063
- Sequence:
MRQMIRSFSE PFGRDLLSIS DGRGRAHNRR GHNDGEDSLT HTDVSSFQTM DQMVSNMRNY MQKLERNFGQ LSVDPNGHSF CSSSVMTYSK IGDEPPKVFQ ASTQTRRAPG GIKETRKAMR DSDSGLEKMA IGHHIHDRAH VIKKSKNKKT GDEEVNQEFI NMNESDAHAF DEEWQSEVLK YKPGRHNLGN TRMRSVGHEN PGSRELKRRE KPQQSPAIEH GRRSNVLGDK LHIKGSSVKS NKK
Genular Protein ID: 517724634
Symbol: B2RD48_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 268
- Mass: 30615
- Checksum: 08706B173293837A
- Sequence:
MFRMLNSSFE DDPFFSESTL AHRENMRQMI RSFSEPFGRD LLSISDGRGR AHNRRGHNDG EDSLTHTDVS SFQTMDQMVS NMRNYMQKLE RNFGQLSVDP NGHSFCSSSV MTYSKIGDEP PKVFQASTQT RRAPGGIKET RKAMRDSDSG LEKMAIGHHI HDRAHVIKKS KNKKTGDEEV NQEFINMNES DAHAFDEEWQ SEVLKYKPGR HNLGNTRMRS VGHENPGSRE LKRREKPQQS PAIEHGRRSN VLGDKLHIKG SSVKSNKK
Genular Protein ID: 2042308157
Symbol: Q2TLE4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 243
- Mass: 27615
- Checksum: 05D187A3860CE17C
- Sequence:
MRQMIRSFSE PFGRDLLSIS DGRGRAHNRR GHNDGEDSLT HTDVSSFQTM DQMVSNMRNY MQKLERNFGQ LSVDPNGHSF CSSSVMTYSK IGDEPPKVFQ ASTQTRRASG GIKETRKAMR DSDSGLEKMA IGHHIHDRAH VIKKSKNKKT GDEEVNQEFI NMNESDAHAF DEEWQSEVLK YKPGRHNLGN TRMRSVGHEN PGSRELKRRE KPQQSPAIEH GRRSNVLGDK LHIKGSSVKS NKK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.