Details for: AFF1

Gene ID: 4299

Symbol: AFF1

Ensembl ID: ENSG00000172493

Description: ALF transcription elongation factor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 433.4431
    Cell Significance Index: -67.4200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 268.4478
    Cell Significance Index: -68.0900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 148.6111
    Cell Significance Index: -61.2200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 143.1790
    Cell Significance Index: -58.1700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 60.9798
    Cell Significance Index: -58.2200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 56.9201
    Cell Significance Index: -70.1800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 29.5442
    Cell Significance Index: -64.6600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 25.6490
    Cell Significance Index: -68.7100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 21.2603
    Cell Significance Index: -65.3000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.0231
    Cell Significance Index: -71.1200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 4.7980
    Cell Significance Index: 123.3300
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 4.0700
    Cell Significance Index: 65.6700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 3.9599
    Cell Significance Index: 96.6200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 3.8074
    Cell Significance Index: 74.3100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 3.7858
    Cell Significance Index: 54.4500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.3353
    Cell Significance Index: 93.2100
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 3.3019
    Cell Significance Index: 29.3100
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 3.0442
    Cell Significance Index: 31.5300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.9212
    Cell Significance Index: 224.1700
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.7437
    Cell Significance Index: 18.5900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 2.6110
    Cell Significance Index: 31.1300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.5694
    Cell Significance Index: 509.9100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.1343
    Cell Significance Index: 147.6000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.0613
    Cell Significance Index: 335.2500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.7944
    Cell Significance Index: 38.3600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5988
    Cell Significance Index: 320.7100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.5385
    Cell Significance Index: 277.3400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.4666
    Cell Significance Index: 36.6600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.4666
    Cell Significance Index: 18.1900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.4469
    Cell Significance Index: 177.9200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.3786
    Cell Significance Index: 77.3600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.3711
    Cell Significance Index: 86.4200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.3260
    Cell Significance Index: 2496.7900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.1965
    Cell Significance Index: 16.3300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.1541
    Cell Significance Index: 19.4400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.0613
    Cell Significance Index: 15.2400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0575
    Cell Significance Index: 115.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.9624
    Cell Significance Index: 611.2500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.6695
    Cell Significance Index: 45.0200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6485
    Cell Significance Index: 41.8400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6032
    Cell Significance Index: 544.6700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.4862
    Cell Significance Index: 896.7500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4790
    Cell Significance Index: 13.8000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4629
    Cell Significance Index: 20.9800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3816
    Cell Significance Index: 168.7000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3420
    Cell Significance Index: 236.5700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2781
    Cell Significance Index: 428.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2777
    Cell Significance Index: 52.8400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2557
    Cell Significance Index: 139.6200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2466
    Cell Significance Index: 111.9300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1948
    Cell Significance Index: 26.7600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1695
    Cell Significance Index: 16.7700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.1655
    Cell Significance Index: 1.0000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1649
    Cell Significance Index: 8.3400
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.1414
    Cell Significance Index: 1.7800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1219
    Cell Significance Index: 4.2900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0894
    Cell Significance Index: 32.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0893
    Cell Significance Index: 121.4500
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.0659
    Cell Significance Index: 0.7000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0492
    Cell Significance Index: 8.4000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.0216
    Cell Significance Index: 2.2500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0024
    Cell Significance Index: 0.1100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0218
    Cell Significance Index: -13.6100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0282
    Cell Significance Index: -4.1000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0424
    Cell Significance Index: -0.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0468
    Cell Significance Index: -34.6900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0503
    Cell Significance Index: -0.4100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0553
    Cell Significance Index: -40.5200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0579
    Cell Significance Index: -0.8600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0628
    Cell Significance Index: -35.4000
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.0762
    Cell Significance Index: -0.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0826
    Cell Significance Index: -62.5400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0884
    Cell Significance Index: -2.3600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1315
    Cell Significance Index: -13.4300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1664
    Cell Significance Index: -21.3300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1816
    Cell Significance Index: -38.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2127
    Cell Significance Index: -61.2000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2183
    Cell Significance Index: -11.3400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2253
    Cell Significance Index: -26.2600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3172
    Cell Significance Index: -16.5200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3957
    Cell Significance Index: -45.1700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4347
    Cell Significance Index: -49.8000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4707
    Cell Significance Index: -33.2900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.4744
    Cell Significance Index: -61.2900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4984
    Cell Significance Index: -23.4300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5089
    Cell Significance Index: -60.0200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5423
    Cell Significance Index: -11.2500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5630
    Cell Significance Index: -29.5600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.5789
    Cell Significance Index: -35.5800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5867
    Cell Significance Index: -8.6600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.6351
    Cell Significance Index: -7.9200
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.6536
    Cell Significance Index: -9.1400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6543
    Cell Significance Index: -28.9400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.6824
    Cell Significance Index: -50.8600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7523
    Cell Significance Index: -59.5800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.7631
    Cell Significance Index: -20.7700
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.7732
    Cell Significance Index: -5.9600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7837
    Cell Significance Index: -16.6900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.8080
    Cell Significance Index: -21.6500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.8234
    Cell Significance Index: -14.1100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AFF1, also known as ALF transcription elongation factor 1, is a protein that belongs to the FMR2 family. It is predominantly expressed in various cell types, including skeletal muscle fibroblasts, renal principal cells, and hepatoblasts. AFF1's primary function is to facilitate the elongation of transcription, a process essential for the regulation of gene expression. Its involvement in transcription elongation complex and super elongation complex pathways underscores its significance in maintaining genomic stability. **Pathways and Functions:** AFF1 is integral to the regulation of gene expression through its involvement in transcription elongation. It interacts with various proteins, including transcription elongation factor complex and super elongation complex, to facilitate the elongation of transcription. This process involves the recruitment of RNA polymerase II and the deposition of nucleotides onto the RNA transcript. AFF1's ability to modulate transcription elongation complex activity highlights its potential role in regulating cellular responses to environmental cues and developmental processes. **Clinical Significance:** Mutations in the AFF1 gene have been associated with neurodevelopmental disorders, such as intellectual disability and autism spectrum disorder. These mutations disrupt the normal functioning of AFF1, leading to aberrant transcription elongation and subsequent cellular dysfunction. The identification of AFF1 as a causative gene for these disorders underscores the importance of its role in maintaining genomic stability and regulating gene expression. In addition to its association with neurodevelopmental disorders, AFF1's involvement in transcription elongation complex and super elongation complex pathways suggests its potential role in various diseases, including cancer and neurodegenerative disorders. Further research into the functions and mechanisms of AFF1 is necessary to fully elucidate its significance in human health and disease. **Conclusion:** In conclusion, AFF1 is a transcription elongation factor that plays a critical role in regulating gene expression. Its involvement in transcription elongation complex and super elongation complex pathways underscores its significance in maintaining genomic stability. The identification of AFF1 as a causative gene for neurodevelopmental disorders highlights its importance in cellular processes. Further research into the functions and mechanisms of AFF1 is necessary to fully elucidate its significance in human health and disease.

Genular Protein ID: 2330154227

Symbol: AFF1_HUMAN

Name: AF4/FMR2 family member 1

UniProtKB Accession Codes:

P51825 B4DTU1 E9PBM3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 6 Ensembl 3 ExpressionAtlas 1 GO 3 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 6 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8506309

Title: Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.

PubMed ID: 8506309

DOI: 10.1073/pnas.90.10.4631

PubMed ID: 8443374

Title: A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias.

PubMed ID: 8443374

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 1423625

Title: The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene.

PubMed ID: 1423625

DOI: 10.1016/0092-8674(92)90603-a

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22195968

Title: The little elongation complex regulates small nuclear RNA transcription.

PubMed ID: 22195968

DOI: 10.1016/j.molcel.2011.12.008

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22895430

Title: The super elongation complex (SEC) family in transcriptional control.

PubMed ID: 22895430

DOI: 10.1038/nrm3417

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23260655

Title: Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.

PubMed ID: 23260655

DOI: 10.1016/j.str.2012.11.011

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 1210
  • Mass: 131422
  • Checksum: F0E334DF8FC2FF04
  • Sequence:
    • MAAQSSLYND DRNLLRIREK ERRNQEAHQE KEAFPEKIPL FGEPYKTAKG DELSSRIQNM 
LGNYEEVKEF LSTKSHTHRL DASENRLGKP KYPLIPDKGS SIPSSSFHTS VHHQSIHTPA 
SGPLSVGNIS HNPKMAQPRT EPMPSLHAKS CGPPDSQHLT QDRLGQEGFG SSHHKKGDRR 
ADGDHCASVT DSAPERELSP LISLPSPVPP LSPIHSNQQT LPRTQGSSKV HGSSNNSKGY 
CPAKSPKDLA VKVHDKETPQ DSLVAPAQPP SQTFPPPSLP SKSVAMQQKP TAYVRPMDGQ 
DQAPSESPEL KPLPEDYRQQ TFEKTDLKVP AKAKLTKLKM PSQSVEQTYS NEVHCVEEIL 
KEMTHSWPPP LTAIHTPSTA EPSKFPFPTK DSQHVSSVTQ NQKQYDTSSK THSNSQQGTS 
SMLEDDLQLS DSEDSDSEQT PEKPPSSSAP PSAPQSLPEP VASAHSSSAE SESTSDSDSS 
SDSESESSSS DSEENEPLET PAPEPEPPTT NKWQLDNWLT KVSQPAAPPE GPRSTEPPRR 
HPESKGSSDS ATSQEHSESK DPPPKSSSKA PRAPPEAPHP GKRSCQKSPA QQEPPQRQTV 
GTKQPKKPVK ASARAGSRTS LQGEREPGLL PYGSRDQTSK DKPKVKTKGR PRAAASNEPK 
PAVPPSSEKK KHKSSLPAPS KALSGPEPAK DNVEDRTPEH FALVPLTESQ GPPHSGSGSR 
TSGCRQAVVV QEDSRKDRLP LPLRDTKLLS PLRDTPPPQS LMVKITLDLL SRIPQPPGKG 
SRQRKAEDKQ PPAGKKHSSE KRSSDSSSKL AKKRKGEAER DCDNKKIRLE KEIKSQSSSS 
SSSHKESSKT KPSRPSSQSS KKEMLPPPPV SSSSQKPAKP ALKRSRREAD TCGQDPPKSA 
SSTKSNHKDS SIPKQRRVEG KGSRSSSEHK GSSGDTANPF PVPSLPNGNS KPGKPQVKFD 
KQQADLHMRE AKKMKQKAEL MTDRVGKAFK YLEAVLSFIE CGIATESESQ SSKSAYSVYS 
ETVDLIKFIM SLKSFSDATA PTQEKIFAVL CMRCQSILNM AMFRCKKDIA IKYSRTLNKH 
FESSSKVAQA PSPCIASTGT PSPLSPMPSP ASSVGSQSSA GSVGSSGVAA TISTPVTIQN 
MTSSYVTITS HVLTAFDLWE QAEALTRKNK EFFARLSTNV CTLALNSSLV DLVHYTRQGF 
QQLQELTKTP

Genular Protein ID: 813006344

Symbol: Q14C88_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q14C88

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 2 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 4 PharmGKB 1 RefSeq 4 SAM 1 SMR 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1211
  • Mass: 131578
  • Checksum: FD08BE7A2BE38BFC
  • Sequence:
    • MAAQSSLYND DRNLLRIREK ERRNQEAHQE KEAFPEKIPL FGEPYKTAKG DELSSRIQNM 
LGNYEEVKEF LSTKSHTHRL DASENRLGKP KYPLIPDKGS SIPSSSFHTS VHHQSIHTPA 
SGPLSVGNIS HNPKMAQPRT EPMPSLHAKS CGPPDSQHLT QDRLGQEGFG SSHHKKGDRR 
ADGDHCASVT DSAPERELSP LISLPSPVPP LSPIHSNQQT LPRTQGSSKV HGSSNNSKGY 
CPAKSPKDLA VKVHDKETPQ DSLVAPAQPP SQTFPPPSLP SKSVAMQQKP TAYVRPMDGQ 
DQAPSESPEL KPLPEDYRQQ TFEKTDLKVP AKAKLTKLKM PSQSVEQTYS NEVHCVEEIL 
KEMTHSWPPP LTAIHTPSTA EPSKFPFPTK DSQHVSSVTQ NQKQYDTSSK THSNSQQGTS 
SMLEDDLQLS DSEDSDSEQT PEKPPSSSAP PSAPQSLPEP VASAHSSSAE SESTSDSDSS 
SDSESESSSS DSEENEPLET PAPEPEPPTT NKWQLDNWLT KVSQPAAPPE GPRSTEPPRR 
HPESKGSSDS ATSQEHSESK DPPPKSSSKA PRAPPEAPHP GKRSCQKSPA QQEPPQRQTV 
GTKQPKKPVK ASARAGSRTS LQGEREPGLL PYGSRDQTSK DKPKVKTKGR PRAAASNEPK 
PAVPPSSEKK KHKSSLPAPS KALSGPEPAK DNVEDRTPEH FALVPLTESQ GPPHSGSGSR 
TSGCRQAVVV QEDSRKDRLP LPLRDTKLLS PLRDTPPPQS LMVKITLDLL SRIPQPPGKG 
SRQRKAEDKQ PPAGKKHSSE KRSSDSSSKL AKKRKGEAER DCDNKKIRLE KEIKSQSSSS 
SSSHKESSKT KPSRPSSQSS KKEMLPPPPV SSSSQKPAKP ALKRSRREAD TCGQDPPKSA 
SSTKSNHKDS SIPKQRRVEG KGSRSSSEHK GSSGDTANPF PVPSLPNGNS KPGKPQVKFD 
KQQADLHMRE AKKMKQKAEL MTDRVGKAFK YLEAVLSFIE CGIATESESQ SSKSAYSVYS 
ETVDLIKFIM SLKSFSDATA PTQEKIFAVL CMRCQSILNM AMFRCKKDIA IKYSRTLNKH 
FESSSKVAQA PSPCIARSTG TPSPLSPMPS PASSVGSQSS AGSVGSSGVA ATISTPVTIQ 
NMTSSYVTIT SHVLTAFDLW EQAEALTRKN KEFFARLSTN VCTLALNSSL VDLVHYTRQG 
FQQLQELTKT P

Genular Protein ID: 3376737744

Symbol: B4DJU9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DJU9

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1

Sequence Information:

  • Length: 849
  • Mass: 91610
  • Checksum: 9812BA3843CC0608
  • Sequence:
    • MTHSWPPPLT AIHTPSTAEP SKFPFPTKDS QHVSSVTQNQ KQYDTSSKTH SNSQQGTSSM 
LEDDLQLSDS EDSDSEQTPE KPPSSSAPPS APQSLPEPVA SAHSSSAESE STSDSDSSSD 
SESESSSSDS EENEPLETPA PEPEPPTTNK WQLDNWLTKV SQPAAPPEGP RSTEPPRRHP 
ESKGSSDSAT SQEHSESKDP PPKSSSKAPR APPEAPHPGK RSCQKSPAQQ EPPQRQTVGT 
KQPKKPVKAS ARAGSRTSLQ GEREPGLLPY GSRDQTSKDK PKVKTKGRPR AAASNEPKPA 
VPPSSEKKKH KSSLPAPSKA LSGPEPAKDN VEDRTPEHFA LVPLTESQGP PHSGSGSRTS 
GCRQAVVVQE DSRKDRLPLP LRDTKLLSPL RDTPPPQSLM VKITLDLLSR IPQPPGKGSR 
QRKAEDKQPP AGKKHSSEKR SSDSSSKLAK KRKGEAERDC DNKKIRLEKE IKSQSSSSSS 
SHKESSKTKP SRPSSQSSKK EMLPPPPVSS SSQKPAKPAL KRSRREADTC GQDPPKSASS 
TKSNHKDSSI PKQRRVEGKG SRSSSEHKGS SGDTANPFPV PSLPNGNSKP GKPQVKFDKQ 
QADLHMREAK KMKQKAELMT DRVGKAFKYL EAVLSFIECG IATESESQSS KSAYSVYSET 
VDLIKFIMSL KSFSDATAPT QEKIFAVLCM RCQSILNMAM FRCKKDIAIK YSRTLNKHFE 
SSSKVAQAPS PCIARSTGTP SPLSPMPSPA SSVGSQSSAG SVGSSGVAAT ISTPVTIQNM 
TSSYVTTTSH VLTAFDLWEQ AEALTRKNKE FFARLSTNVC TLALNSSLVD LVHYTRQGFQ 
QLQELTKTP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.