Details for: AFF1

Gene ID: 4299

Symbol: AFF1

Ensembl ID: ENSG00000172493

Description: ALF transcription elongation factor 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 3.5
    Marker Score: 2,301
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.43
    Marker Score: 8,596
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 3.37
    Marker Score: 2,594
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 3.23
    Marker Score: 4,339
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 3.17
    Marker Score: 2,743
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.17
    Marker Score: 13,249
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 3.15
    Marker Score: 10,314
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.14
    Marker Score: 3,561
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 3.04
    Marker Score: 2,699
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.91
    Marker Score: 5,595
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.86
    Marker Score: 61,083
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.79
    Marker Score: 4,058
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.74
    Marker Score: 1,363
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.73
    Marker Score: 799
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.7
    Marker Score: 3,102
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.69
    Marker Score: 60,148
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.63
    Marker Score: 2,510
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.61
    Marker Score: 1,417
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 2.61
    Marker Score: 1,811
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 2.53
    Marker Score: 915
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 2.5
    Marker Score: 1,316
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.49
    Marker Score: 1,489
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.46
    Marker Score: 2,980
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.44
    Marker Score: 770
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 2.42
    Marker Score: 698
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.38
    Marker Score: 1,323
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.37
    Marker Score: 2,556
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.36
    Marker Score: 5,171
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.32
    Marker Score: 736
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: 2.3
    Marker Score: 744
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 2.26
    Marker Score: 822
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.18
    Marker Score: 1,218
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.16
    Marker Score: 1,424
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.14
    Marker Score: 2,368
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.13
    Marker Score: 2,659
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 2.13
    Marker Score: 8,895
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.08
    Marker Score: 873
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 2.02
    Marker Score: 5,090
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.02
    Marker Score: 18,959
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 2.01
    Marker Score: 629
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2
    Marker Score: 32,177
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2
    Marker Score: 986
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.99
    Marker Score: 3,474
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.98
    Marker Score: 503
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.97
    Marker Score: 1,998
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.94
    Marker Score: 6,906
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.94
    Marker Score: 71,514
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.94
    Marker Score: 2,075
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.92
    Marker Score: 6,842
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.82
    Marker Score: 1,065
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.79
    Marker Score: 1,042
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.79
    Marker Score: 16,966
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.77
    Marker Score: 601
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.76
    Marker Score: 525
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.74
    Marker Score: 911
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.74
    Marker Score: 450
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.71
    Marker Score: 105,209
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.68
    Marker Score: 1,452
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.67
    Marker Score: 2,368
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.66
    Marker Score: 3,911
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.66
    Marker Score: 619
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.64
    Marker Score: 3,342
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.62
    Marker Score: 789
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.62
    Marker Score: 444
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.6
    Marker Score: 1,686
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.57
    Marker Score: 507
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.57
    Marker Score: 1,068
  • Cell Name: oocyte (CL0000023)
    Fold Change: 1.57
    Marker Score: 387
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.56
    Marker Score: 1,104
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.56
    Marker Score: 6,477
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.56
    Marker Score: 494
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.54
    Marker Score: 310
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.53
    Marker Score: 668
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.52
    Marker Score: 1,533
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.52
    Marker Score: 573
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.5
    Marker Score: 550
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.49
    Marker Score: 1,122
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.49
    Marker Score: 12,792
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: 1.49
    Marker Score: 448
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.47
    Marker Score: 339
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.47
    Marker Score: 543
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.47
    Marker Score: 15,155
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 1.45
    Marker Score: 822
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.44
    Marker Score: 9,274
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.38
    Marker Score: 5,966
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.38
    Marker Score: 1,464
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.37
    Marker Score: 1,463
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.37
    Marker Score: 3,906
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.36
    Marker Score: 7,326
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.35
    Marker Score: 1,209
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.33
    Marker Score: 1,602
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.33
    Marker Score: 537
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.32
    Marker Score: 327
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.32
    Marker Score: 740
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.32
    Marker Score: 363
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.32
    Marker Score: 20,626
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.31
    Marker Score: 23,241
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.31
    Marker Score: 1,201
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.31
    Marker Score: 13,239
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.3
    Marker Score: 342

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AFF1, also known as ALF transcription elongation factor 1, is a protein that belongs to the FMR2 family. It is predominantly expressed in various cell types, including skeletal muscle fibroblasts, renal principal cells, and hepatoblasts. AFF1's primary function is to facilitate the elongation of transcription, a process essential for the regulation of gene expression. Its involvement in transcription elongation complex and super elongation complex pathways underscores its significance in maintaining genomic stability. **Pathways and Functions:** AFF1 is integral to the regulation of gene expression through its involvement in transcription elongation. It interacts with various proteins, including transcription elongation factor complex and super elongation complex, to facilitate the elongation of transcription. This process involves the recruitment of RNA polymerase II and the deposition of nucleotides onto the RNA transcript. AFF1's ability to modulate transcription elongation complex activity highlights its potential role in regulating cellular responses to environmental cues and developmental processes. **Clinical Significance:** Mutations in the AFF1 gene have been associated with neurodevelopmental disorders, such as intellectual disability and autism spectrum disorder. These mutations disrupt the normal functioning of AFF1, leading to aberrant transcription elongation and subsequent cellular dysfunction. The identification of AFF1 as a causative gene for these disorders underscores the importance of its role in maintaining genomic stability and regulating gene expression. In addition to its association with neurodevelopmental disorders, AFF1's involvement in transcription elongation complex and super elongation complex pathways suggests its potential role in various diseases, including cancer and neurodegenerative disorders. Further research into the functions and mechanisms of AFF1 is necessary to fully elucidate its significance in human health and disease. **Conclusion:** In conclusion, AFF1 is a transcription elongation factor that plays a critical role in regulating gene expression. Its involvement in transcription elongation complex and super elongation complex pathways underscores its significance in maintaining genomic stability. The identification of AFF1 as a causative gene for neurodevelopmental disorders highlights its importance in cellular processes. Further research into the functions and mechanisms of AFF1 is necessary to fully elucidate its significance in human health and disease.

Genular Protein ID: 2330154227

Symbol: AFF1_HUMAN

Name: AF4/FMR2 family member 1

UniProtKB Accession Codes:

P51825 B4DTU1 E9PBM3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CORUM 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 6 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 3 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 6 SAM 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8506309

Title: Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.

PubMed ID: 8506309

DOI: 10.1073/pnas.90.10.4631

PubMed ID: 8443374

Title: A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias.

PubMed ID: 8443374

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 1423625

Title: The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene.

PubMed ID: 1423625

DOI: 10.1016/0092-8674(92)90603-a

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22195968

Title: The little elongation complex regulates small nuclear RNA transcription.

PubMed ID: 22195968

DOI: 10.1016/j.molcel.2011.12.008

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22895430

Title: The super elongation complex (SEC) family in transcriptional control.

PubMed ID: 22895430

DOI: 10.1038/nrm3417

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23260655

Title: Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.

PubMed ID: 23260655

DOI: 10.1016/j.str.2012.11.011

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 1210
  • Mass: 131422
  • Checksum: F0E334DF8FC2FF04
  • Sequence:
    • MAAQSSLYND DRNLLRIREK ERRNQEAHQE KEAFPEKIPL FGEPYKTAKG DELSSRIQNM 
LGNYEEVKEF LSTKSHTHRL DASENRLGKP KYPLIPDKGS SIPSSSFHTS VHHQSIHTPA 
SGPLSVGNIS HNPKMAQPRT EPMPSLHAKS CGPPDSQHLT QDRLGQEGFG SSHHKKGDRR 
ADGDHCASVT DSAPERELSP LISLPSPVPP LSPIHSNQQT LPRTQGSSKV HGSSNNSKGY 
CPAKSPKDLA VKVHDKETPQ DSLVAPAQPP SQTFPPPSLP SKSVAMQQKP TAYVRPMDGQ 
DQAPSESPEL KPLPEDYRQQ TFEKTDLKVP AKAKLTKLKM PSQSVEQTYS NEVHCVEEIL 
KEMTHSWPPP LTAIHTPSTA EPSKFPFPTK DSQHVSSVTQ NQKQYDTSSK THSNSQQGTS 
SMLEDDLQLS DSEDSDSEQT PEKPPSSSAP PSAPQSLPEP VASAHSSSAE SESTSDSDSS 
SDSESESSSS DSEENEPLET PAPEPEPPTT NKWQLDNWLT KVSQPAAPPE GPRSTEPPRR 
HPESKGSSDS ATSQEHSESK DPPPKSSSKA PRAPPEAPHP GKRSCQKSPA QQEPPQRQTV 
GTKQPKKPVK ASARAGSRTS LQGEREPGLL PYGSRDQTSK DKPKVKTKGR PRAAASNEPK 
PAVPPSSEKK KHKSSLPAPS KALSGPEPAK DNVEDRTPEH FALVPLTESQ GPPHSGSGSR 
TSGCRQAVVV QEDSRKDRLP LPLRDTKLLS PLRDTPPPQS LMVKITLDLL SRIPQPPGKG 
SRQRKAEDKQ PPAGKKHSSE KRSSDSSSKL AKKRKGEAER DCDNKKIRLE KEIKSQSSSS 
SSSHKESSKT KPSRPSSQSS KKEMLPPPPV SSSSQKPAKP ALKRSRREAD TCGQDPPKSA 
SSTKSNHKDS SIPKQRRVEG KGSRSSSEHK GSSGDTANPF PVPSLPNGNS KPGKPQVKFD 
KQQADLHMRE AKKMKQKAEL MTDRVGKAFK YLEAVLSFIE CGIATESESQ SSKSAYSVYS 
ETVDLIKFIM SLKSFSDATA PTQEKIFAVL CMRCQSILNM AMFRCKKDIA IKYSRTLNKH 
FESSSKVAQA PSPCIASTGT PSPLSPMPSP ASSVGSQSSA GSVGSSGVAA TISTPVTIQN 
MTSSYVTITS HVLTAFDLWE QAEALTRKNK EFFARLSTNV CTLALNSSLV DLVHYTRQGF 
QQLQELTKTP

Genular Protein ID: 813006344

Symbol: Q14C88_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q14C88

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 ExpressionAtlas 1 GO 2 Gene3D 1 GenomeRNAi 1 InterPro 3 KEGG 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 4 PharmGKB 1 RefSeq 4 SAM 1 SMR 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1211
  • Mass: 131578
  • Checksum: FD08BE7A2BE38BFC
  • Sequence:
    • MAAQSSLYND DRNLLRIREK ERRNQEAHQE KEAFPEKIPL FGEPYKTAKG DELSSRIQNM 
LGNYEEVKEF LSTKSHTHRL DASENRLGKP KYPLIPDKGS SIPSSSFHTS VHHQSIHTPA 
SGPLSVGNIS HNPKMAQPRT EPMPSLHAKS CGPPDSQHLT QDRLGQEGFG SSHHKKGDRR 
ADGDHCASVT DSAPERELSP LISLPSPVPP LSPIHSNQQT LPRTQGSSKV HGSSNNSKGY 
CPAKSPKDLA VKVHDKETPQ DSLVAPAQPP SQTFPPPSLP SKSVAMQQKP TAYVRPMDGQ 
DQAPSESPEL KPLPEDYRQQ TFEKTDLKVP AKAKLTKLKM PSQSVEQTYS NEVHCVEEIL 
KEMTHSWPPP LTAIHTPSTA EPSKFPFPTK DSQHVSSVTQ NQKQYDTSSK THSNSQQGTS 
SMLEDDLQLS DSEDSDSEQT PEKPPSSSAP PSAPQSLPEP VASAHSSSAE SESTSDSDSS 
SDSESESSSS DSEENEPLET PAPEPEPPTT NKWQLDNWLT KVSQPAAPPE GPRSTEPPRR 
HPESKGSSDS ATSQEHSESK DPPPKSSSKA PRAPPEAPHP GKRSCQKSPA QQEPPQRQTV 
GTKQPKKPVK ASARAGSRTS LQGEREPGLL PYGSRDQTSK DKPKVKTKGR PRAAASNEPK 
PAVPPSSEKK KHKSSLPAPS KALSGPEPAK DNVEDRTPEH FALVPLTESQ GPPHSGSGSR 
TSGCRQAVVV QEDSRKDRLP LPLRDTKLLS PLRDTPPPQS LMVKITLDLL SRIPQPPGKG 
SRQRKAEDKQ PPAGKKHSSE KRSSDSSSKL AKKRKGEAER DCDNKKIRLE KEIKSQSSSS 
SSSHKESSKT KPSRPSSQSS KKEMLPPPPV SSSSQKPAKP ALKRSRREAD TCGQDPPKSA 
SSTKSNHKDS SIPKQRRVEG KGSRSSSEHK GSSGDTANPF PVPSLPNGNS KPGKPQVKFD 
KQQADLHMRE AKKMKQKAEL MTDRVGKAFK YLEAVLSFIE CGIATESESQ SSKSAYSVYS 
ETVDLIKFIM SLKSFSDATA PTQEKIFAVL CMRCQSILNM AMFRCKKDIA IKYSRTLNKH 
FESSSKVAQA PSPCIARSTG TPSPLSPMPS PASSVGSQSS AGSVGSSGVA ATISTPVTIQ 
NMTSSYVTIT SHVLTAFDLW EQAEALTRKN KEFFARLSTN VCTLALNSSL VDLVHYTRQG 
FQQLQELTKT P

Genular Protein ID: 3376737744

Symbol: B4DJU9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DJU9

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 2 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1

Sequence Information:

  • Length: 849
  • Mass: 91610
  • Checksum: 9812BA3843CC0608
  • Sequence:
    • MTHSWPPPLT AIHTPSTAEP SKFPFPTKDS QHVSSVTQNQ KQYDTSSKTH SNSQQGTSSM 
LEDDLQLSDS EDSDSEQTPE KPPSSSAPPS APQSLPEPVA SAHSSSAESE STSDSDSSSD 
SESESSSSDS EENEPLETPA PEPEPPTTNK WQLDNWLTKV SQPAAPPEGP RSTEPPRRHP 
ESKGSSDSAT SQEHSESKDP PPKSSSKAPR APPEAPHPGK RSCQKSPAQQ EPPQRQTVGT 
KQPKKPVKAS ARAGSRTSLQ GEREPGLLPY GSRDQTSKDK PKVKTKGRPR AAASNEPKPA 
VPPSSEKKKH KSSLPAPSKA LSGPEPAKDN VEDRTPEHFA LVPLTESQGP PHSGSGSRTS 
GCRQAVVVQE DSRKDRLPLP LRDTKLLSPL RDTPPPQSLM VKITLDLLSR IPQPPGKGSR 
QRKAEDKQPP AGKKHSSEKR SSDSSSKLAK KRKGEAERDC DNKKIRLEKE IKSQSSSSSS 
SHKESSKTKP SRPSSQSSKK EMLPPPPVSS SSQKPAKPAL KRSRREADTC GQDPPKSASS 
TKSNHKDSSI PKQRRVEGKG SRSSSEHKGS SGDTANPFPV PSLPNGNSKP GKPQVKFDKQ 
QADLHMREAK KMKQKAELMT DRVGKAFKYL EAVLSFIECG IATESESQSS KSAYSVYSET 
VDLIKFIMSL KSFSDATAPT QEKIFAVLCM RCQSILNMAM FRCKKDIAIK YSRTLNKHFE 
SSSKVAQAPS PCIARSTGTP SPLSPMPSPA SSVGSQSSAG SVGSSGVAAT ISTPVTIQNM 
TSSYVTTTSH VLTAFDLWEQ AEALTRKNKE FFARLSTNVC TLALNSSLVD LVHYTRQGFQ 
QLQELTKTP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.