Details for: NKTR
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 682.7275
Cell Significance Index: -106.2000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 391.5537
Cell Significance Index: -99.3200 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 275.5205
Cell Significance Index: -113.5000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 242.0769
Cell Significance Index: -114.2900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 231.0113
Cell Significance Index: -93.8500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 210.8148
Cell Significance Index: -108.4400 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 170.3968
Cell Significance Index: -114.3400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 98.8434
Cell Significance Index: -94.3700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 90.7940
Cell Significance Index: -111.9500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 37.5085
Cell Significance Index: -100.4800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 32.0532
Cell Significance Index: -98.4500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 28.7477
Cell Significance Index: -113.4400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 25.7198
Cell Significance Index: -56.2900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 3.8589
Cell Significance Index: 216.5400 - Cell Name: preadipocyte (CL0002334)
Fold Change: 3.2241
Cell Significance Index: 62.9300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.5467
Cell Significance Index: 505.4100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.4722
Cell Significance Index: 495.9200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 2.4342
Cell Significance Index: 35.0100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.2476
Cell Significance Index: 145.0100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.2081
Cell Significance Index: 61.7100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.0996
Cell Significance Index: 753.0900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.9111
Cell Significance Index: 117.4700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.8047
Cell Significance Index: 247.8400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.7533
Cell Significance Index: 190.7100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.6447
Cell Significance Index: 74.5500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.5982
Cell Significance Index: 83.2500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.4026
Cell Significance Index: 107.6300 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.2986
Cell Significance Index: 15.4800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.2395
Cell Significance Index: 857.2600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.2353
Cell Significance Index: 222.6900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.1897
Cell Significance Index: 649.7500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.1632
Cell Significance Index: 51.4500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.1612
Cell Significance Index: 78.0800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.1540
Cell Significance Index: 33.2500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.1122
Cell Significance Index: 136.7500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.0092
Cell Significance Index: 119.0200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.9906
Cell Significance Index: 37.5100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.9472
Cell Significance Index: 121.4200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.8912
Cell Significance Index: 565.9800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.8615
Cell Significance Index: 45.2300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.7986
Cell Significance Index: 9.9100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.7851
Cell Significance Index: 347.1200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.6920
Cell Significance Index: 1302.9800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6275
Cell Significance Index: 566.6000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.5552
Cell Significance Index: 13.3200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4853
Cell Significance Index: 22.8100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.4171
Cell Significance Index: 769.1600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.3878
Cell Significance Index: 597.0100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3469
Cell Significance Index: 7.5200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.2986
Cell Significance Index: 135.5400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1958
Cell Significance Index: 266.2700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1042
Cell Significance Index: 3.6200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0709
Cell Significance Index: 2.4900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0367
Cell Significance Index: 3.6300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0298
Cell Significance Index: 0.5100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0223
Cell Significance Index: 1.0400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0041
Cell Significance Index: -2.9900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0352
Cell Significance Index: -26.1100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0380
Cell Significance Index: -7.2300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0474
Cell Significance Index: -8.0900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0833
Cell Significance Index: -63.0300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1040
Cell Significance Index: -64.9300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1259
Cell Significance Index: -9.3800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1587
Cell Significance Index: -89.4800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1629
Cell Significance Index: -4.3500 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.1664
Cell Significance Index: -1.2800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1683
Cell Significance Index: -11.9000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.2030
Cell Significance Index: -33.0200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2352
Cell Significance Index: -30.3900 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.2505
Cell Significance Index: -4.2200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2955
Cell Significance Index: -4.9500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2976
Cell Significance Index: -62.6800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2990
Cell Significance Index: -15.5300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3007
Cell Significance Index: -30.7200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3172
Cell Significance Index: -8.3400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3231
Cell Significance Index: -46.9700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3521
Cell Significance Index: -101.3100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.3645
Cell Significance Index: -25.2100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4420
Cell Significance Index: -27.8600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5468
Cell Significance Index: -63.7200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.6561
Cell Significance Index: -75.1700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6881
Cell Significance Index: -71.6500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.6977
Cell Significance Index: -18.9900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.7757
Cell Significance Index: -46.5700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.7993
Cell Significance Index: -19.9800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.8331
Cell Significance Index: -23.8800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.8800
Cell Significance Index: -100.4500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -1.1750
Cell Significance Index: -33.5300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.2851
Cell Significance Index: -101.7800 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.3584
Cell Significance Index: -20.0500 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -1.3860
Cell Significance Index: -21.0500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -1.5154
Cell Significance Index: -31.7200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.6975
Cell Significance Index: -45.4900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.8121
Cell Significance Index: -111.1000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.8275
Cell Significance Index: -38.9200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.8414
Cell Significance Index: -39.3600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.8542
Cell Significance Index: -47.3700 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -1.8622
Cell Significance Index: -28.3300 - Cell Name: peg cell (CL4033014)
Fold Change: -1.9257
Cell Significance Index: -44.4900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -2.0099
Cell Significance Index: -44.0100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3746892291
Symbol: NKTR_HUMAN
Name: Natural-killer cells cyclophilin-related protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8421688
Title: A cyclophilin-related protein involved in the function of natural killer cells.
PubMed ID: 8421688
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 20676357
Title: Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PubMed ID: 20676357
Sequence Information:
- Length: 1462
- Mass: 165677
- Checksum: D98A1147763EF527
- Sequence:
MGAQDRPQCH FDIEINREPV GRIMFQLFSD ICPKTCKNFL CLCSGEKGLG KTTGKKLCYK GSTFHRVVKN FMIQGGDFSE GNGKGGESIY GGYFKDENFI LKHDRAFLLS MANRGKHTNG SQFFITTKPA PHLDGVHVVF GLVISGFEVI EQIENLKTDA ASRPYADVRV IDCGVLATKS IKDVFEKKRK KPTHSEGSDS SSNSSSSSES SSESELEHER SRRRKHKRRP KVKRSKKRRK EASSSEEPRN KHAMNPKGHS ERSDTNEKRS VDSSAKREKP VVRPEEIPPV PENRFLLRRD MPVVTAEPEP KIPDVAPIVS DQKPSVSKSG RKIKGRGTIR YHTPPRSRSC SESDDDDSSE TPPHWKEEMQ RLRAYRPPSG EKWSKGDKLS DPCSSRWDER SLSQRSRSWS YNGYYSDLST ARHSGHHKKR RKEKKVKHKK KGKKQKHCRR HKQTKKRRIL IPSDIESSKS STRRMKSSCD RERSSRSSSL SSHHSSKRDW SKSDKDVQSS LTHSSRDSYR SKSHSQSYSR GSSRSRTASK SSSHSRSRSK SRSSSKSGHR KRASKSPRKT ASQLSENKPV KTEPLRATMA QNENVVVQPV VAENIPVIPL SDSPPPSRWK PGQKPWKPSY ERIQEMKAKT THLLPIQSTY SLANIKETGS SSSYHKREKN SESDQSTYSK YSDRSSESSP RSRSRSSRSR SYSRSYTRSR SLASSHSRSR SPSSRSHSRN KYSDHSQCSR SSSYTSISSD DGRRAKRRLR SSGKKNSVSH KKHSSSSEKT LHSKYVKGRD RSSCVRKYSE SRSSLDYSSD SEQSSVQATQ SAQEKEKQGQ MERTHNKQEK NRGEEKSKSE RECPHSKKRT LKENLSDHLR NGSKPKRKNY AGSKWDSESN SERDVTKNSK NDSHPSSDKE EGEATSDSES EVSEIHIKVK PTTKSSTNTS LPDDNGAWKS SKQRTSTSDS EGSCSNSENN RGKPQKHKHG SKENLKREHT KKVKEKLKGK KDKKHKAPKR KQAFHWQPPL EFGEEEEEEI DDKQVTQESK EKKVSENNET IKDNILKTEK SSEEDLSGKH DTVTVSSDLD QFTKDDSKLS ISPTALNTEE NVACLQNIQH VEESVPNGVE DVLQTDDNME ICTPDRSSPA KVEETSPLGN ARLDTPDINI VLKQDMATEH PQAEVVKQES SMSESKVLGE VGKQDSSSAS LASAGESTGK KEVAEKSQIN LIDKKWKPLQ GVGNLAAPNA ATSSAVEVKV LTTVPEMKPQ GLRIEIKSKN KVRPGSLFDE VRKTARLNRR PRNQESSSDE QTPSRDDDSQ SRSPSRSRSK SETKSRHRTR SVSYSHSRSR SRSSTSSYRS RSYSRSRSRG WYSRGRTRSR SSSYRSYKSH RTSSRSRSRS SSYDPHSRSR SYTYDSYYSR SRSRSRSQRS DSYHRGRSYN RRSRSCRSYG SDSESDRSYS HHRSPSESSR YS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.