Details for: NPHS1

Gene ID: 4868

Symbol: NPHS1

Ensembl ID: ENSG00000161270

Description: NPHS1 adhesion molecule, nephrin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: kidney cell (CL1000497)
    Fold Change: 2.6064
    Cell Significance Index: 20.8100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.7904
    Cell Significance Index: 25.3200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.5891
    Cell Significance Index: 14.2700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2701
    Cell Significance Index: 5.9200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2375
    Cell Significance Index: 4.0700
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.2249
    Cell Significance Index: 1.8600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1917
    Cell Significance Index: 31.1800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1777
    Cell Significance Index: 9.9700
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.1744
    Cell Significance Index: 2.4200
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.1707
    Cell Significance Index: 2.2100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1408
    Cell Significance Index: 8.4600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1088
    Cell Significance Index: 10.7700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1080
    Cell Significance Index: 2.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1038
    Cell Significance Index: 4.5900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0919
    Cell Significance Index: 3.4800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0772
    Cell Significance Index: 1.6500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0764
    Cell Significance Index: 14.5400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0753
    Cell Significance Index: 1.9800
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.0712
    Cell Significance Index: 1.0000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0613
    Cell Significance Index: 2.7800
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.0594
    Cell Significance Index: 0.7200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0505
    Cell Significance Index: 10.0300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0493
    Cell Significance Index: 8.4100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0447
    Cell Significance Index: 0.6100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0400
    Cell Significance Index: 8.0200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0387
    Cell Significance Index: 4.2100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0373
    Cell Significance Index: 6.7200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0358
    Cell Significance Index: 1.6700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0328
    Cell Significance Index: 0.7100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0325
    Cell Significance Index: 1.1300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0306
    Cell Significance Index: 10.9800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0156
    Cell Significance Index: 1.0500
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.0048
    Cell Significance Index: 0.0500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0028
    Cell Significance Index: 0.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0027
    Cell Significance Index: 4.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0018
    Cell Significance Index: 3.2300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0009
    Cell Significance Index: 1.7700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0003
    Cell Significance Index: -0.3400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0004
    Cell Significance Index: -0.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0004
    Cell Significance Index: -0.3300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0017
    Cell Significance Index: -0.9700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0037
    Cell Significance Index: -2.3400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0050
    Cell Significance Index: -0.3500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0051
    Cell Significance Index: -3.8700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0057
    Cell Significance Index: -4.2100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0057
    Cell Significance Index: -1.6500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0058
    Cell Significance Index: -2.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0062
    Cell Significance Index: -3.4000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0063
    Cell Significance Index: -3.9200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0094
    Cell Significance Index: -1.1500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0098
    Cell Significance Index: -0.1400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0101
    Cell Significance Index: -0.6200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0103
    Cell Significance Index: -1.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0108
    Cell Significance Index: -0.2700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0135
    Cell Significance Index: -2.8500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0181
    Cell Significance Index: -2.1100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0185
    Cell Significance Index: -2.1200
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.0226
    Cell Significance Index: -0.1800
  • Cell Name: diffuse bipolar 2 cell (CL4033028)
    Fold Change: -0.0228
    Cell Significance Index: -0.2800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0234
    Cell Significance Index: -3.2100
  • Cell Name: invaginating midget bipolar cell (CL4033034)
    Fold Change: -0.0235
    Cell Significance Index: -0.2900
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.0243
    Cell Significance Index: -0.2100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0265
    Cell Significance Index: -0.4000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0281
    Cell Significance Index: -2.8700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0290
    Cell Significance Index: -3.7500
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0303
    Cell Significance Index: -0.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0360
    Cell Significance Index: -4.2400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0360
    Cell Significance Index: -3.7500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0393
    Cell Significance Index: -2.0400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0452
    Cell Significance Index: -2.8500
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -0.0459
    Cell Significance Index: -0.5700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0481
    Cell Significance Index: -3.6900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0494
    Cell Significance Index: -2.3200
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0510
    Cell Significance Index: -0.7000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0515
    Cell Significance Index: -3.8400
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0517
    Cell Significance Index: -0.6500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0537
    Cell Significance Index: -4.2500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0543
    Cell Significance Index: -1.5500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0544
    Cell Significance Index: -1.7200
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0599
    Cell Significance Index: -0.8700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0623
    Cell Significance Index: -2.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0623
    Cell Significance Index: -4.0200
  • Cell Name: diffuse bipolar 4 cell (CL4033031)
    Fold Change: -0.0649
    Cell Significance Index: -0.7900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0667
    Cell Significance Index: -3.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0673
    Cell Significance Index: -1.8800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0681
    Cell Significance Index: -1.3300
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0691
    Cell Significance Index: -0.4100
  • Cell Name: diffuse bipolar 3a cell (CL4033029)
    Fold Change: -0.0756
    Cell Significance Index: -0.9100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0757
    Cell Significance Index: -1.9500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0769
    Cell Significance Index: -2.4500
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0784
    Cell Significance Index: -1.1900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0794
    Cell Significance Index: -2.7800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0805
    Cell Significance Index: -2.8300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0864
    Cell Significance Index: -2.5500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0916
    Cell Significance Index: -3.0000
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0922
    Cell Significance Index: -0.6000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0991
    Cell Significance Index: -2.6500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1026
    Cell Significance Index: -2.4600
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.1032
    Cell Significance Index: -1.7000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1032
    Cell Significance Index: -3.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** Nephrin is a transmembrane protein composed of four immunoglobulin-like domains, which are crucial for its function in cell-cell adhesion. It is highly expressed in podocytes, the specialized cells of the glomerular filtration barrier. Nephrin is also found in other tissues, including the brain, where it is involved in the development and maintenance of the blood-brain barrier. The protein's structure and localization are critical for its function, as it interacts with other proteins to form the slit diaphragm, a complex structure that regulates the passage of molecules across the glomerular filtration barrier. **Pathways and Functions:** Nephrin's primary function is to maintain the integrity of the slit diaphragm, a complex structure that regulates the passage of molecules across the glomerular filtration barrier. The formation and maintenance of the slit diaphragm involve the interaction of nephrin with other proteins, including podocin, nephrotin, and CD2AP. This complex structure regulates the passage of molecules, including ions, glucose, and proteins, across the glomerular filtration barrier. Nephrin's function in the slit diaphragm also regulates the activity of the Wnt/β-catenin signaling pathway, which is involved in cell proliferation, differentiation, and survival. In addition to its role in maintaining the slit diaphragm, nephrin has been implicated in other cellular processes, including cell adhesion, migration, and signaling. Nephrin's interaction with other proteins, such as N-cadherin and β-catenin, regulates the formation and maintenance of cell-cell adhesions and junctions. Nephrin's role in these processes is critical for the development and function of the glomerular filtration barrier and other tissues, including the brain and skeletal muscle. **Clinical Significance:** Dysfunction or loss of nephrin has been implicated in various kidney diseases, including nephrotic syndrome and focal segmental glomerulosclerosis (FSGS). Nephrotic syndrome is characterized by the loss of large amounts of protein in the urine, leading to edema, hypoalbuminemia, and hyperlipidemia. FSGS is a common cause of nephrotic syndrome, and its pathogenesis is thought to involve the disruption of the slit diaphragm, leading to the loss of large amounts of protein in the urine. In addition to its role in kidney disease, nephrin's dysfunction has also been implicated in other diseases, including nephrotic syndrome, focal segmental glomerulosclerosis (FSGS), and certain types of cancer, such as renal cell carcinoma. The development of therapies targeting nephrin and the slit diaphragm has provided new hope for the treatment of these diseases. In conclusion, nephrin is a critical component of the slit diaphragm, a structure that regulates the passage of molecules across the glomerular filtration barrier. Its dysfunction has been implicated in various kidney diseases, including nephrotic syndrome and FSGS. Further research into the role of nephrin in human disease will provide new insights into the pathogenesis of these diseases and the development of effective therapies.

Genular Protein ID: 2797946999

Symbol: NPHN_HUMAN

Name: Nephrin

UniProtKB Accession Codes:

O60500 A6NDH2 C3RX61

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 5 Ensembl 2 EvolutionaryTrace 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9660941

Title: Positionally cloned gene for a novel glomerular protein -- nephrin -- is mutated in congenital nephrotic syndrome.

PubMed ID: 9660941

DOI: 10.1016/s1097-2765(00)80057-x

PubMed ID: 19309778

Title: Novel human pathological mutations. Gene symbol: NPHS1. Disease: congenital nephrotic syndrome, Finnish type.

PubMed ID: 19309778

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 10550324

Title: Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney.

PubMed ID: 10550324

DOI: 10.1016/s0002-9440(10)65483-1

PubMed ID: 10393930

Title: Nephrin is specifically located at the slit diaphragm of glomerular podocytes.

PubMed ID: 10393930

DOI: 10.1073/pnas.96.14.7962

PubMed ID: 11562357

Title: Interaction with podocin facilitates nephrin signaling.

PubMed ID: 11562357

DOI: 10.1074/jbc.c100452200

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 28955049

Title: C1-Ten is a PTPase of nephrin, regulating podocyte hypertrophy through mTORC1 activation.

PubMed ID: 28955049

DOI: 10.1038/s41598-017-12382-8

PubMed ID: 9915943

Title: Structure of the gene for congenital nephrotic syndrome of the Finnish type (NPHS1) and characterization of mutations.

PubMed ID: 9915943

DOI: 10.1086/302182

PubMed ID: 10652016

Title: Novel mutation in the nephrin gene of a Japanese patient with congenital nephrotic syndrome of the Finnish type.

PubMed ID: 10652016

DOI: 10.1046/j.1523-1755.2000.00859.x

PubMed ID: 11726550

Title: Defective nephrin trafficking caused by missense mutations in the NPHS1 gene: insight into the mechanisms of congenital nephrotic syndrome.

PubMed ID: 11726550

DOI: 10.1093/hmg/10.23.2637

PubMed ID: 11317351

Title: Mutation spectrum in the nephrin gene (NPHS1) in congenital nephrotic syndrome.

PubMed ID: 11317351

DOI: 10.1002/humu.1111

PubMed ID: 17290294

Title: A familial childhood-onset relapsing nephrotic syndrome.

PubMed ID: 17290294

DOI: 10.1038/sj.ki.5002110

PubMed ID: 18614772

Title: Nephrin mutations can cause childhood-onset steroid-resistant nephrotic syndrome.

PubMed ID: 18614772

DOI: 10.1681/asn.2008010059

PubMed ID: 18503012

Title: Thirteen novel NPHS1 mutations in a large cohort of children with congenital nephrotic syndrome.

PubMed ID: 18503012

DOI: 10.1093/ndt/gfn271

PubMed ID: 20172850

Title: Nineteen novel NPHS1 mutations in a worldwide cohort of patients with congenital nephrotic syndrome (CNS).

PubMed ID: 20172850

DOI: 10.1093/ndt/gfq088

PubMed ID: 22009864

Title: Two novel NPHS1 mutations in a Chinese family with congenital nephrotic syndrome.

PubMed ID: 22009864

DOI: 10.4238/2011.october.18.1

PubMed ID: 20798252

Title: Immunosuppression and renal outcome in congenital and pediatric steroid-resistant nephrotic syndrome.

PubMed ID: 20798252

DOI: 10.2215/cjn.01190210

PubMed ID: 22732337

Title: Mutations in podocyte genes are a rare cause of primary FSGS associated with ESRD in adult patients.

PubMed ID: 22732337

DOI: 10.5414/cn107320

PubMed ID: 22565185

Title: A spectrum of novel NPHS1 and NPHS2 gene mutations in pediatric nephrotic syndrome patients from Pakistan.

PubMed ID: 22565185

DOI: 10.1016/j.gene.2012.04.063

PubMed ID: 23595123

Title: A molecular genetic analysis of childhood nephrotic syndrome in a cohort of Saudi Arabian families.

PubMed ID: 23595123

DOI: 10.1038/jhg.2013.27

PubMed ID: 25804400

Title: SIPA1L3 identified by linkage analysis and whole-exome sequencing as a novel gene for autosomal recessive congenital cataract.

PubMed ID: 25804400

DOI: 10.1038/ejhg.2015.46

PubMed ID: 26560236

Title: NPHS1 gene mutations confirm congenital nephrotic syndrome in four Brazilian cases: a novel mutation is described.

PubMed ID: 26560236

DOI: 10.1111/nep.12667

Sequence Information:

  • Length: 1241
  • Mass: 134742
  • Checksum: 7F5AFAF078BCF532
  • Sequence:
    • MALGTTLRAS LLLLGLLTEG LAQLAIPASV PRGFWALPEN LTVVEGASVE LRCGVSTPGS 
AVQWAKDGLL LGPDPRIPGF PRYRLEGDPA RGEFHLHIEA CDLSDDAEYE CQVGRSEMGP 
ELVSPRVILS ILVPPKLLLL TPEAGTMVTW VAGQEYVVNC VSGDAKPAPD ITILLSGQTI 
SDISANVNEG SQQKLFTVEA TARVTPRSSD NRQLLVCEAS SPALEAPIKA SFTVNVLFPP 
GPPVIEWPGL DEGHVRAGQS LELPCVARGG NPLATLQWLK NGQPVSTAWG TEHTQAVARS 
VLVMTVRPED HGAQLSCEAH NSVSAGTQEH GITLQVTFPP SAIIILGSAS QTENKNVTLS 
CVSKSSRPRV LLRWWLGWRQ LLPMEETVMD GLHGGHISMS NLTFLARRED NGLTLTCEAF 
SEAFTKETFK KSLILNVKYP AQKLWIEGPP EGQKLRAGTR VRLVCLAIGG NPEPSLMWYK 
DSRTVTESRL PQESRRVHLG SVEKSGSTFS RELVLVTGPS DNQAKFTCKA GQLSASTQLA 
VQFPPTNVTI LANASALRPG DALNLTCVSV SSNPPVNLSW DKEGERLEGV AAPPRRAPFK 
GSAAARSVLL QVSSRDHGQR VTCRAHSAEL RETVSSFYRL NVLYRPEFLG EQVLVVTAVE 
QGEALLPVSV SANPAPEAFN WTFRGYRLSP AGGPRHRILS SGALHLWNVT RADDGLYQLH 
CQNSEGTAEA RLRLDVHYAP TIRALQDPTE VNVGGSVDIV CTVDANPILP GMFNWERLGE 
DEEDQSLDDM EKISRGPTGR LRIHHAKLAQ AGAYQCIVDN GVAPPARRLL RLVVRFAPQV 
EHPTPLTKVA AAGDSTSSAT LHCRARGVPN IVFTWTKNGV PLDLQDPRYT EHTYHQGGVH 
SSLLTIANVS AAQDYALFTC TATNALGSDQ TNIQLVSISR PDPPSGLKVV SLTPHSVGLE 
WKPGFDGGLP QRFCIRYEAL GTPGFHYVDV VPPQATTFTL TGLQPSTRYR VWLLASNALG 
DSGLADKGTQ LPITTPGLHQ PSGEPEDQLP TEPPSGPSGL PLLPVLFALG GLLLLSNASC 
VGGVLWQRRL RRLAEGISEK TEAGSEEDRV RNEYEESQWT GERDTQSSTV STTEAEPYYR 
SLRDFSPQLP PTQEEVSYSR GFTGEDEDMA FPGHLYDEVE RTYPPSGAWG PLYDEVQMGP 
WDLHWPEDTY QDPRGIYDQV AGDLDTLEPD SLPFELRGHL V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.