Details for: NUCB2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 284.6118
Cell Significance Index: -44.2700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 151.3542
Cell Significance Index: -62.3500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 140.0589
Cell Significance Index: -66.1300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 133.7207
Cell Significance Index: -54.3300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 122.9429
Cell Significance Index: -63.2400 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 98.9461
Cell Significance Index: -66.4000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 73.9227
Cell Significance Index: -18.7500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 56.8216
Cell Significance Index: -54.2500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 47.5686
Cell Significance Index: -58.6500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 18.5975
Cell Significance Index: -49.8200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 15.6612
Cell Significance Index: -61.8000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 13.6710
Cell Significance Index: -41.9900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 10.7733
Cell Significance Index: 288.1800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 10.0841
Cell Significance Index: -22.0700 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: 7.2834
Cell Significance Index: 151.9000 - Cell Name: peg cell (CL4033014)
Fold Change: 6.5092
Cell Significance Index: 150.3900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 5.0132
Cell Significance Index: 233.7400 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 4.9940
Cell Significance Index: 31.8800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 4.3844
Cell Significance Index: 510.9500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 3.3953
Cell Significance Index: 219.0500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 2.4996
Cell Significance Index: 426.8200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 2.1503
Cell Significance Index: 349.7300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.8160
Cell Significance Index: 48.4900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.7584
Cell Significance Index: 131.0500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.5865
Cell Significance Index: 217.8700 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.5241
Cell Significance Index: 9.4700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.3936
Cell Significance Index: 151.5900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.3281
Cell Significance Index: 79.7300 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 1.1546
Cell Significance Index: 7.6600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.1067
Cell Significance Index: 222.0000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.0965
Cell Significance Index: 48.5000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9927
Cell Significance Index: 356.0700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.9296
Cell Significance Index: 35.2000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.8858
Cell Significance Index: 24.1100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.8820
Cell Significance Index: 481.6600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8603
Cell Significance Index: 776.7900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.8232
Cell Significance Index: 42.8800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.7086
Cell Significance Index: 140.6200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.7037
Cell Significance Index: 14.7300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.6118
Cell Significance Index: 78.4300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.5603
Cell Significance Index: 38.7500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4675
Cell Significance Index: 88.9700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.4471
Cell Significance Index: 5.3300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.4293
Cell Significance Index: 55.4600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3374
Cell Significance Index: 20.7400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.3323
Cell Significance Index: 15.6200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3217
Cell Significance Index: 142.2300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2921
Cell Significance Index: 202.0200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.2245
Cell Significance Index: 2.5500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2224
Cell Significance Index: 27.3400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1948
Cell Significance Index: 12.2800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1648
Cell Significance Index: 9.2500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1200
Cell Significance Index: 225.9400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1198
Cell Significance Index: 21.6000 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.1179
Cell Significance Index: 3.1000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1036
Cell Significance Index: 5.4400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0829
Cell Significance Index: 62.7500 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.0425
Cell Significance Index: 0.8300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0403
Cell Significance Index: 62.1000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0339
Cell Significance Index: 62.5500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0065
Cell Significance Index: 4.1500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0112
Cell Significance Index: -15.2400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0177
Cell Significance Index: -13.1300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0248
Cell Significance Index: -18.1600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0485
Cell Significance Index: -30.3100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0557
Cell Significance Index: -25.2700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0565
Cell Significance Index: -5.5900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0607
Cell Significance Index: -4.6600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0613
Cell Significance Index: -34.5800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0704
Cell Significance Index: -0.9600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0837
Cell Significance Index: -8.5500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1031
Cell Significance Index: -21.7200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1231
Cell Significance Index: -2.0600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1435
Cell Significance Index: -2.4600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1486
Cell Significance Index: -17.5200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1595
Cell Significance Index: -11.2800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1631
Cell Significance Index: -10.9700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1652
Cell Significance Index: -4.2200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1694
Cell Significance Index: -48.7400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1782
Cell Significance Index: -5.1400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1989
Cell Significance Index: -6.9100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2122
Cell Significance Index: -5.9300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2326
Cell Significance Index: -33.8100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2799
Cell Significance Index: -31.9500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3196
Cell Significance Index: -36.6200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.4422
Cell Significance Index: -20.0500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5357
Cell Significance Index: -55.7800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5608
Cell Significance Index: -29.1300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.5867
Cell Significance Index: -15.0800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5901
Cell Significance Index: -18.9000 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.7068
Cell Significance Index: -4.3500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7138
Cell Significance Index: -43.7600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7225
Cell Significance Index: -57.2300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.8589
Cell Significance Index: -24.6200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.8694
Cell Significance Index: -20.8500 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.8976
Cell Significance Index: -7.5400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.0983
Cell Significance Index: -23.3900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -1.1226
Cell Significance Index: -32.9700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -1.1460
Cell Significance Index: -42.0700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.1679
Cell Significance Index: -31.3000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1148242881
Symbol: NUCB2_HUMAN
Name: DNA-binding protein NEFA
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7811391
Title: Human protein NEFA, a novel DNA binding/EF-hand/leucine zipper protein. Molecular cloning and sequence analysis of the cDNA, isolation and characterization of the protein.
PubMed ID: 7811391
PubMed ID: 9639681
Title: Assembly of a high-resolution map of the Acadian Usher syndrome region and localization of the nuclear EF-hand acidic gene.
PubMed ID: 9639681
PubMed ID: 12087473
Title: Serological identification and expression analysis of gastric cancer-associated genes.
PubMed ID: 12087473
PubMed ID: 20427483
Title: Troglitazone, a ligand of peroxisome proliferator-activated receptor-gamma, stabilizes NUCB2 (Nesfatin) mRNA by activating the ERK1/2 pathway: isolation and characterization of the human NUCB2 gene.
PubMed ID: 20427483
DOI: 10.1210/en.2009-1169
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 11749975
Title: Golgi retention of human protein NEFA is mediated by its N-terminal Leu/Ile-rich region.
PubMed ID: 11749975
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 30194280
Title: A biochemical and genetic discovery pipeline identifies PLCdelta4b as a nonreceptor activator of heterotrimeric G-proteins.
PubMed ID: 30194280
Sequence Information:
- Length: 420
- Mass: 50223
- Checksum: ABA74587B72C33FE
- Sequence:
MRWRTILLQY CFLLITCLLT ALEAVPIDID KTKVQNIHPV ESAKIEPPDT GLYYDEYLKQ VIDVLETDKH FREKLQKADI EEIKSGRLSK ELDLVSHHVR TKLDELKRQE VGRLRMLIKA KLDSLQDIGM DHQALLKQFD HLNHLNPDKF ESTDLDMLIK AATSDLEHYD KTRHEEFKKY EMMKEHERRE YLKTLNEEKR KEEESKFEEM KKKHENHPKV NHPGSKDQLK EVWEETDGLD PNDFDPKTFF KLHDVNSDGF LDEQELEALF TKELEKVYDP KNEEDDMVEM EEERLRMREH VMNEVDTNKD RLVTLEEFLK ATEKKEFLEP DSWETLDQQQ FFTEEELKEY ENIIALQENE LKKKADELQK QKEELQRQHD QLEAQKLEYH QVIQQMEQKK LQQGIPPSGP AGELKFEPHI
Genular Protein ID: 3885277042
Symbol: Q2L696_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 390
- Mass: 46630
- Checksum: DB4FA8B2882C4BA6
- Sequence:
MRWRTILLQY CFLLITCLLT ALEAVPIDID KTKVQNIHPV ESAKIEPPDT GLYYDEYLKQ VIDVLETDKH FREKLQKADI EEIKSGRLSK ELDLVSHHVR TKLDELKRQE VGRLRMLIKA KLDSLQDIGM DHQALLKQFD HLNHLNPDKF ESTDLDMLIK AATSDLEHYD KTRHEEFKKY EMMKEHERRE YLKTLNEEKR KEEESKFEEM KKKHENHPKV NHPGSKDQLK EVWEETDGLD PNDFDPKTFF KLHDVNSDGF LDEQELEALF TKELEKVYDP KNEEDDMVEM EEERLRMREH VMNETLDQQQ FFTEEELKEY ENIIALQENE LKKKADELQK QKEELQRQHD QLEAQKLEYH QVIQQMEQKK LQQGIPPSGP AGELKFEPHI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.