Details for: ZBTB21

Gene ID: 49854

Symbol: ZBTB21

Ensembl ID: ENSG00000173276

Description: zinc finger and BTB domain containing 21

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 126.9084
    Cell Significance Index: -19.7400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 73.5284
    Cell Significance Index: -18.6500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 43.4764
    Cell Significance Index: -17.9100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 41.0063
    Cell Significance Index: -19.3600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 39.2485
    Cell Significance Index: -15.9500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 16.8160
    Cell Significance Index: -16.0600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.1644
    Cell Significance Index: -19.9300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.1374
    Cell Significance Index: -19.1200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.0709
    Cell Significance Index: -20.0100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.5032
    Cell Significance Index: 71.7600
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.4394
    Cell Significance Index: 23.7200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.3853
    Cell Significance Index: 18.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0775
    Cell Significance Index: 106.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.0691
    Cell Significance Index: 29.1000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.0531
    Cell Significance Index: 16.9000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0305
    Cell Significance Index: 167.6000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8024
    Cell Significance Index: 724.5000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.6602
    Cell Significance Index: 17.6900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6253
    Cell Significance Index: 37.5400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6088
    Cell Significance Index: 122.1200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4535
    Cell Significance Index: 23.5600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3890
    Cell Significance Index: 27.5100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3556
    Cell Significance Index: 16.1200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3499
    Cell Significance Index: 7.5800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3257
    Cell Significance Index: 144.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3207
    Cell Significance Index: 39.4300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3037
    Cell Significance Index: 108.9200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3000
    Cell Significance Index: 20.7500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2862
    Cell Significance Index: 51.6000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2677
    Cell Significance Index: 16.8700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2611
    Cell Significance Index: 51.8100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.2520
    Cell Significance Index: 157.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1948
    Cell Significance Index: 26.7500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1947
    Cell Significance Index: 37.0500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.1842
    Cell Significance Index: 21.0300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1646
    Cell Significance Index: 7.7400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1142
    Cell Significance Index: 62.3900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0984
    Cell Significance Index: 5.1300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.0950
    Cell Significance Index: 1.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0882
    Cell Significance Index: 4.1100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0857
    Cell Significance Index: 11.0800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0830
    Cell Significance Index: 5.3600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0801
    Cell Significance Index: 2.1400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0718
    Cell Significance Index: 1.9200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0605
    Cell Significance Index: 10.3300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0504
    Cell Significance Index: 1.7700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0426
    Cell Significance Index: 5.4600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0382
    Cell Significance Index: 4.3800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0376
    Cell Significance Index: 70.7900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0344
    Cell Significance Index: 52.9400
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.0273
    Cell Significance Index: 0.2900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0187
    Cell Significance Index: 11.8900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0135
    Cell Significance Index: 24.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0036
    Cell Significance Index: -2.7000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0044
    Cell Significance Index: -3.2600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0083
    Cell Significance Index: -11.2500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0109
    Cell Significance Index: -1.5800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0127
    Cell Significance Index: -7.1800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0132
    Cell Significance Index: -5.9800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0153
    Cell Significance Index: -1.1400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0187
    Cell Significance Index: -14.1200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0221
    Cell Significance Index: -1.2400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0235
    Cell Significance Index: -0.5000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0306
    Cell Significance Index: -2.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0452
    Cell Significance Index: -9.5300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0467
    Cell Significance Index: -4.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0533
    Cell Significance Index: -1.5400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0541
    Cell Significance Index: -6.3900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0544
    Cell Significance Index: -15.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0618
    Cell Significance Index: -7.2000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0773
    Cell Significance Index: -4.7500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0781
    Cell Significance Index: -1.6200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0827
    Cell Significance Index: -2.3100
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: -0.0976
    Cell Significance Index: -0.2200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1164
    Cell Significance Index: -8.9300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1307
    Cell Significance Index: -5.7800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1575
    Cell Significance Index: -5.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1658
    Cell Significance Index: -17.2600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1705
    Cell Significance Index: -1.0300
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.1817
    Cell Significance Index: -2.5500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1895
    Cell Significance Index: -15.0100
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.1920
    Cell Significance Index: -1.4800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1945
    Cell Significance Index: -10.2100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1990
    Cell Significance Index: -5.6800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2104
    Cell Significance Index: -12.9000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2129
    Cell Significance Index: -6.8200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2189
    Cell Significance Index: -11.0600
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2202
    Cell Significance Index: -3.2500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2742
    Cell Significance Index: -9.5300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2936
    Cell Significance Index: -3.5000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2966
    Cell Significance Index: -7.8000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3028
    Cell Significance Index: -5.9100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3343
    Cell Significance Index: -7.3200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3619
    Cell Significance Index: -8.3600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3639
    Cell Significance Index: -13.3600
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.3659
    Cell Significance Index: -3.8200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3825
    Cell Significance Index: -7.0700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3832
    Cell Significance Index: -12.1200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3859
    Cell Significance Index: -9.2600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3902
    Cell Significance Index: -6.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ZBTB21 is characterized by its ability to bind to specific DNA sequences, thereby regulating transcriptional activity. Its protein structure consists of a BTB domain, a zinc finger domain, and a Poz domain, which confer its ability to interact with RNA polymerase II and other transcriptional regulators. ZBTB21 is highly expressed in various cell types, including hematopoietic progenitor cells, embryonic stem cells, and epithelial cells. Its expression is tightly regulated by post-translational modifications, such as phosphorylation and ubiquitination, which modulate its activity and localization. **Pathways and Functions:** ZBTB21 is involved in several key pathways, including: 1. **Transcriptional Repression:** ZBTB21 acts as a transcriptional repressor by binding to specific DNA sequences and recruiting co-repressors, such as histone deacetylases and chromatin-modifying enzymes, to silence gene expression. 2. **Immune Cell Development:** ZBTB21 plays a crucial role in regulating the development and differentiation of immune cells, including T cells, B cells, and dendritic cells. 3. **Epithelial Barrier Function:** ZBTB21 is involved in maintaining epithelial barrier function, particularly in the gut and respiratory epithelium, by regulating the expression of tight junction proteins and antimicrobial peptides. 4. **Stromal Cell Regulation:** ZBTB21 regulates the function of stromal cells in bone marrow, liver, and other organs, influencing their ability to support hematopoiesis and tissue repair. **Clinical Significance:** Dysregulation of ZBTB21 has been implicated in various autoimmune and inflammatory disorders, including: 1. **Autoimmune Diseases:** ZBTB21 has been linked to autoimmune diseases, such as rheumatoid arthritis, lupus, and multiple sclerosis, where it contributes to the dysregulation of immune cell development and function. 2. **Inflammatory Disorders:** ZBTB21 has been implicated in inflammatory disorders, such as asthma and inflammatory bowel disease, where it regulates the expression of genes involved in inflammation and tissue repair. 3. **Cancer:** ZBTB21 has been identified as a tumor suppressor gene in various types of cancer, including leukemia and lymphoma, where it regulates the expression of genes involved in cell proliferation and survival. In conclusion, ZBTB21 is a critical transcriptional repressor protein that plays a pivotal role in regulating immune cell development, differentiation, and function. Its dysregulation has been implicated in various autoimmune and inflammatory disorders, highlighting its potential as a therapeutic target for the treatment of these diseases.

Genular Protein ID: 2558966379

Symbol: ZBT21_HUMAN

Name: Zinc finger and BTB domain-containing protein 21

UniProtKB Accession Codes:

Q9ULJ3 Q5R2W1 Q5R2W2 Q6P4R0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 10 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15629158

Title: Novel human BTB/POZ domain-containing zinc finger protein ZNF295 is directly associated with ZFP161.

PubMed ID: 15629158

DOI: 10.1016/j.bbrc.2004.12.048

PubMed ID: 10574462

Title: Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10574462

DOI: 10.1093/dnares/6.5.337

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 1066
  • Mass: 118870
  • Checksum: E1779E26943FDAC8
  • Sequence:
    • MEGLLHYINP AHAISLLSAL NEERLKGQLC DVLLIVGDQK FRAHKNVLAA SSEYFQSLFT 
NKENESQTVF QLDFCEPDAF DNVLNYIYSS SLFVEKSSLA AVQELGYSLG ISFLTNIVSK 
TPQAPFPTCP NRKKVFVEDD ENSSQKRSVI VCQSRNEAQG KTVSQNQPDV SHTSRPSPSI 
AVKANTNKPH VPKPIEPLHN LSLTEKSWPK DSSVVYAKSL EHSGSLDDPN RISLVKRNAV 
LPSKPLQDRE AMDDKPGVSG QLPKGKALEL ALKRPRPPVL SVCSSSETPY LLKETNKGNG 
QGEDRNLLYY SKLGLVIPSS GSGSGNQSID RSGPLVKSLL RRSLSMDSQV PVYSPSIDLK 
SSQGSSSVSS DAPGNVLCAL SQKSSLKDCS EKTALDDRPQ VLQPHRLRSF SASQSTDREG 
ASPVTEVRIK TEPSSPLSDP SDIIRVTVGD AATTAAASSS SVTRDLSLKT EDDQKDMSRL 
PAKRRFQADR RLPFKKLKVN EHGSPVSEDN FEEGSSPTLL DADFPDSDLN KDEFGELEGT 
RPNKKFKCKH CLKIFRSTAG LHRHVNMYHN PEKPYACDIC HKRFHTNFKV WTHCQTQHGI 
VKNPSPASSS HAVLDEKFQR KLIDIVRERE IKKALIIKLR RGKPGFQGQS SSQAQQVIKR 
NLRSRAKGAY ICTYCGKAYR FLSQFKQHIK MHPGEKPLGV NKVAKPKEHA PLASPVENKE 
VYQCRLCNAK LSSLLEQGSH ERLCRNAAVC PYCSLRFFSP ELKQEHESKC EYKKLTCLEC 
MRTFKSSFSI WRHQVEVHNQ NNMAPTENFS LPVLDHNGDV TGSSRPQSQP EPNKVNHIVT 
TKDDNVFSDS SEQVNFDSED SSCLPEDLSL SKQLKIQVKE EPVEEAEEEA PEASTAPKEA 
GPSKEASLWP CEKCGKMFTV HKQLERHQEL LCSVKPFICH VCNKAFRTNF RLWSHFQSHM 
SQASEESAHK ESEVCPVPTN SPSPPPLPPP PPLPKIQPLE PDSPTGLSEN PTPATEKLFV 
PQESDTLFYH APPLSAITFK RQFMCKLCHR TFKTAFSLWS HEQTHN

Genular Protein ID: 1727339573

Symbol: Q5H9S0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5H9S0

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 763
  • Mass: 84513
  • Checksum: 29D773E1EE294853
  • Sequence:
    • MEGLLHYINP AHAISLLSAL NEERLKGQLC DVLLIVGDQK FRAHKNVLAA SSEYFQSLFT 
NKENESQTVF QLDFCEPDAF DNVLNYIYSS SLFVEKSSLA AVQELGYSLG ISFLTNIVSK 
TPQAPFPTCP NRKKVFVEDD ENSSQKRSVI VCQSRNEAQG KTVSQNQPDV SHTSRPSPSI 
AVKANTNKPH VPKPIEPLHN LSLTEKSWPK DSSVVYAKSL EHSGSLDDPN RISLVKRNAV 
LPSKPLQDRE ATDDKPGVSG QLPKGKALEL ALKRPRPPVL SVCSSSETPY LLKETNKGNG 
QGEDRNLLYY SKLGLVIPSS GSGSGNQSID RSGPLVKSLL RRSLSMDSQA PVYSPSIDLK 
SSQGSSSVSS DAPGNVLCAL SQKSSLKDCS EKTALDDRPQ VLQPHRLRSF SASQSTDREG 
ASPVTEVRIK TEPSSPLSDP SDIIRVTVGD AATTAAASSS SVTRDLSLKT EDDQKDMSRL 
PAKRRFQADR RLPFKKLKVN EHGSPVSEDN FEEGSSPTLL DADFPDSDLN KDEFGELEGT 
RPNKKFKCKH CLKIFRSTAG LHRHVNMYHN PEKPYACDIC HKRFHTNFKV WTHCQTQHGI 
VKNPSPASSS HAVLDEKFQR KLIDIVRERE IKKALIIKLR RGKPGFQGQS SSQAQQVIKR 
NLRSRAKGAY ICTYCGKAYR FLSQFKQHIK MHPGEKPLGV NKVAKPKEHA PLASPVENKE 
VYQCRLCNAK LSSLLEQGSH ERLCRNAAVC PYCSLRFFSP ELK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.